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The map label for this gene is ftsW [H]

Identifier: 195977897

GI number: 195977897

Start: 797019

End: 798233

Strand: Direct

Name: ftsW [H]

Synonym: Sez_0767

Alternate gene names: 195977897

Gene position: 797019-798233 (Clockwise)

Preceding gene: 195977896

Following gene: 195977898

Centisome position: 39.38

GC content: 40.91

Gene sequence:

>1215_bases
ATGTTACCCAAGAGAAAATTAATTGATCAACGTCTTGATTATGCCATTATTTTTCCTGTTTTTTGTTTGCTAATATTTGG
TCTGGTATCTGTATATGTGGCAGCAAGTCATGATTTTCCGCAAAGCCTCGCCACTGTTATGCTTCAGCAGGTTCTCTGGA
TCCTTCTTGGAGCTGTCATTGCCTTTACCCTAATGTTTTTTAGCACAGAGATTCTGTGGAAATTAACACCTGTCTTTTAT
CTTTTGGGTGTGCTATTAATGGTTCTGCCACTCATCTTTTTTAGCCCTCGGCTGGTAGCTGCTACAGGGGCGAAAAATTG
GATTACGATTGGCTCAATGACCTTGTTTCAACCATCAGAATTTATGAAAATATCCTACATTCTGGCAATGTCTCGGTTAA
CGGTCTGGTTTAAGAGAAGGCAGGAGAGAAGTCGGTTTTTAGATGATTGGAAGCTCTTGGGCTTATACCTTGTCTTGACG
TTGCCGGTCATGGTCCTGCTAGCACTGCAAAAGGACTTAGGAACAGCTATGGTTTTTTTAGCCATCTTAGCTGGAATTAT
CTTAATTTCAGGGATTTCTTGGTGGCTTATTTTACCAGCCTTGGCACTAGTCTTTTTCCTAGTTTCAGCTTTTTTCTTTG
TTTTTTTGTTGCCAGAGGGAAAAGAATTCCTTTTAAAAATGGGAATGGATACCTACCAATTGAATCGTATTTCAGCTTGG
CTGACACCGTTTGATTTCTCAGATACCATTGCCTATCAGCAGACGCAAAGTATGATTTCGATTGGGAGTGGTGGCTTTTT
TGGTAAGGGCTTTAATCAGCTTGAGCTGTCAGTACCAGTCAGAGAAAGTGATATGATTTTTACAGTGATCGCTGAAAATT
TTGGCTTTCTTGGTGCAGCTAGCTTACTGATCTTGTATTTAATACTGATTTACCGCATGCTTAGGGTGACCTTTGCATCG
AATAACCTTTTTTATACCTACATTTCAACCGGCTTTATCATGATGATACTATTTCATATTTTTGAAAACATTGGCGCAGC
AGTTGGTCTGCTACCTTTGACCGGTATTCCCCTTCCCTTTATTTCTCAGGGCGGCTCCTCGTTGATTTCAAATCTGATTG
GGGTCGGTCTGATCCTATCGATGAACTACCAGCACGTCCTTGCTCATGAAAAGCAAAGCGAGCATGAGCTCAGCAGAAGC
TCACGTTATGTTTAA

Upstream 100 bases:

>100_bases
GGGATGACCTGCGGTGGTCATCTCTAGAGCTCCTTGCTTCTTTTTTTATGTAGACTAATGGTTTAGACTGCTAGCTTCTT
TGTTTAGAAAGTAGGACATC

Downstream 100 bases:

>100_bases
GAGGCATGTTTGGCTCTTGTTCGGTTAGAATGAGCTGCCAATCAGCCTTTTTTTATTTGTTTAATCGCTATAAAAATAAA
GAAAAATATGTTATAATTAA

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLATVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFY
LLGVLLMVLPLIFFSPRLVAATGAKNWITIGSMTLFQPSEFMKISYILAMSRLTVWFKRRQERSRFLDDWKLLGLYLVLT
LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALALVFFLVSAFFFVFLLPEGKEFLLKMGMDTYQLNRISAW
LTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLELSVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFAS
NNLFYTYISTGFIMMILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQSEHELSRS
SRYV

Sequences:

>Translated_404_residues
MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLATVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFY
LLGVLLMVLPLIFFSPRLVAATGAKNWITIGSMTLFQPSEFMKISYILAMSRLTVWFKRRQERSRFLDDWKLLGLYLVLT
LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALALVFFLVSAFFFVFLLPEGKEFLLKMGMDTYQLNRISAW
LTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLELSVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFAS
NNLFYTYISTGFIMMILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQSEHELSRS
SRYV
>Mature_404_residues
MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLATVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFY
LLGVLLMVLPLIFFSPRLVAATGAKNWITIGSMTLFQPSEFMKISYILAMSRLTVWFKRRQERSRFLDDWKLLGLYLVLT
LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALALVFFLVSAFFFVFLLPEGKEFLLKMGMDTYQLNRISAW
LTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLELSVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFAS
NNLFYTYISTGFIMMILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQSEHELSRS
SRYV

Specific function: This Is One Of The Proteins Responsible For The Rod Shape Of E. coli. Is Required For The Expression Of The Enzymatic Activity Of Pbp2, Which Is Thought To Synthesize Peptidoglycan In The Step Of Initiation Of Cell Elongation. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=390, Percent_Identity=30.7692307692308, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1786277, Length=338, Percent_Identity=26.6272189349112, Blast_Score=95, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45601; Mature: 45601

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLATVMLQQVLWILLGAVI
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
AFTLMFFSTEILWKLTPVFYLLGVLLMVLPLIFFSPRLVAATGAKNWITIGSMTLFQPSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEECCEEEECCHH
FMKISYILAMSRLTVWFKRRQERSRFLDDWKLLGLYLVLTLPVMVLLALQKDLGTAMVFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILAGIILISGISWWLILPALALVFFLVSAFFFVFLLPEGKEFLLKMGMDTYQLNRISAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHH
LTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLELSVPVRESDMIFTVIAENFGFLGAA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEHHHCCCHHHHH
SLLILYLILIYRMLRVTFASNNLFYTYISTGFIMMILFHIFENIGAAVGLLPLTGIPLPF
HHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ISQGGSSLISNLIGVGLILSMNYQHVLAHEKQSEHELSRSSRYV
HCCCHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLATVMLQQVLWILLGAVI
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
AFTLMFFSTEILWKLTPVFYLLGVLLMVLPLIFFSPRLVAATGAKNWITIGSMTLFQPSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEECCEEEECCHH
FMKISYILAMSRLTVWFKRRQERSRFLDDWKLLGLYLVLTLPVMVLLALQKDLGTAMVFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILAGIILISGISWWLILPALALVFFLVSAFFFVFLLPEGKEFLLKMGMDTYQLNRISAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHH
LTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLELSVPVRESDMIFTVIAENFGFLGAA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEHHHCCCHHHHH
SLLILYLILIYRMLRVTFASNNLFYTYISTGFIMMILFHIFENIGAAVGLLPLTGIPLPF
HHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ISQGGSSLISNLIGVGLILSMNYQHVLAHEKQSEHELSRSSRYV
HCCCHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]