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The map label for this gene is add [H]

Identifier: 195977881

GI number: 195977881

Start: 780412

End: 781437

Strand: Direct

Name: add [H]

Synonym: Sez_0749

Alternate gene names: 195977881

Gene position: 780412-781437 (Clockwise)

Preceding gene: 195977877

Following gene: 195977882

Centisome position: 38.55

GC content: 43.66

Gene sequence:

>1026_bases
TTGGAAACAAAAGATTTAAAGAAGCTTGCTAAAGCTGAGCTGCACTGCCATTTAGACGGTTCTTTGTCATTAGACACTAT
TCGTCAATTGGCGGCTTTGGCGCAGGTAGATGTTCCTCAAGATGATTCTGAGTTAAAGCAGCTGGTAACCGCACCGGAAA
CCTGCGGATCCTTGATGGATTATTTAAAAACCTTTGATTTTATCAGACCATTATTACAAACGCCTCAGGCTTTAACATTG
GCTGCTTATGATGTTGTGAAGCAGGCTGCCCTTGAAAATGTCATCTACATTGAAATTCGATTTGCTCCTGAGCTATCAAT
GGATCAGGGTCTGACCGCTACTCAGGTGGTAGAGGCAGTCCTAAAAGGACTTGAGCAAGGACAAAAAGAGTTTGGCATTG
TCGCTAAGGCTATTGTGTGTGGCATGCGTCAGTCCTCACTAGACATTAGCAGAGAGATTTTTGCAAATGTCTTAGAGTGG
GCCAACAAAGGCTTGGTAGGCTTTGATTTTGCAGGCAACGAGCTGGACTTTCCTCCAGCTGTCTTAGCAGATCTGATCAA
AGAGACTCAGGCCTATGGGTTACCATTTACGCTTCACGCTGGTGAGTGCGGCTGTCCAAACTATATTGTTGATGCTATTG
ATTTAGGTATCAAACGCTTAGGGCATGTGACGGCCATTCATAACCAAAAGGATTTATTGGCCAAGTTTATCGCCAATGAT
GTGACAGCAGAGCTATGCTTCACGAGTAATCTACAAACCAAGGCTGCTAGGACTGTTGAGGACTTTCCTTATATGCAGCT
AAGGCAGGCTGGCGCTAAATTATCCATTAACACAGACAATCGGACAGTATCAGATACTAACCTGACAAAGGAATACGAAC
TGTTTGTCAAGCATTTTGAGACAAGCGTCTCAGACTTTTTGGAACACAATCGTGATGCAATTAAGGCCAGCTTTACCAGT
CCAGCTGAAAAAGAAGCTTTATTGGCTCGTTTGGACAAGGCCTATCAGTCTTACATCAAGAAATGA

Upstream 100 bases:

>100_bases
AAAATGCGGTCCTTCCGTTGCTTTTTGAGAAAATGCTCACTTGCTTTTTGGCAATTTTTTGGTATCATACTAAAAAATAG
ACTTAATAAGGAGATACAGC

Downstream 100 bases:

>100_bases
TGCTTTTCTTGGCAAAGTATGATAAAATATACTGATATTTAGTTATTTTGGGAGGAAATTATGGCATTAGCCAAAATCGT
TTATGCCAGCATGACAGGAA

Product: adenosine deaminase Add

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSELKQLVTAPETCGSLMDYLKTFDFIRPLLQTPQALTL
AAYDVVKQAALENVIYIEIRFAPELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIKRLGHVTAIHNQKDLLAKFIAND
VTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSINTDNRTVSDTNLTKEYELFVKHFETSVSDFLEHNRDAIKASFTS
PAEKEALLARLDKAYQSYIKK

Sequences:

>Translated_341_residues
METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSELKQLVTAPETCGSLMDYLKTFDFIRPLLQTPQALTL
AAYDVVKQAALENVIYIEIRFAPELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIKRLGHVTAIHNQKDLLAKFIAND
VTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSINTDNRTVSDTNLTKEYELFVKHFETSVSDFLEHNRDAIKASFTS
PAEKEALLARLDKAYQSYIKK
>Mature_341_residues
METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSELKQLVTAPETCGSLMDYLKTFDFIRPLLQTPQALTL
AAYDVVKQAALENVIYIEIRFAPELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIKRLGHVTAIHNQKDLLAKFIAND
VTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSINTDNRTVSDTNLTKEYELFVKHFETSVSDFLEHNRDAIKASFTS
PAEKEALLARLDKAYQSYIKK

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=345, Percent_Identity=29.2753623188406, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI226693318, Length=333, Percent_Identity=24.024024024024, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI61175224, Length=228, Percent_Identity=26.7543859649123, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787910, Length=324, Percent_Identity=28.3950617283951, Blast_Score=120, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI32565969, Length=340, Percent_Identity=25.8823529411765, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17538512, Length=340, Percent_Identity=25.8823529411765, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI115537133, Length=323, Percent_Identity=23.8390092879257, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324188, Length=341, Percent_Identity=22.5806451612903, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24645260, Length=331, Percent_Identity=23.8670694864048, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 37749; Mature: 37749

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSELKQLVTAPETCGSLMD
CCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHH
YLKTFDFIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFAPELSMDQGLTATQVVEAV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCHHHHHHHH
LKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEWANKGLVGFDFAGNELDFPPA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHH
VLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIKRLGHVTAIHNQKDLLAKFIAND
HHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSINTDNRTVSDTNLTKEYELFVKHFE
HHHHHHHCCCCHHHHHHHHHHCCHHHHHHCCCEEEECCCCCEECCCCCHHHHHHHHHHHH
TSVSDFLEHNRDAIKASFTSPAEKEALLARLDKAYQSYIKK
HHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSELKQLVTAPETCGSLMD
CCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHH
YLKTFDFIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFAPELSMDQGLTATQVVEAV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCHHHHHHHH
LKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEWANKGLVGFDFAGNELDFPPA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHH
VLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIKRLGHVTAIHNQKDLLAKFIAND
HHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSINTDNRTVSDTNLTKEYELFVKHFE
HHHHHHHCCCCHHHHHHHHHHCCHHHHHHCCCEEEECCCCCEECCCCCHHHHHHHHHHHH
TSVSDFLEHNRDAIKASFTSPAEKEALLARLDKAYQSYIKK
HHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA