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The map label for this gene is bga [H]

Identifier: 195977873

GI number: 195977873

Start: 773887

End: 775671

Strand: Direct

Name: bga [H]

Synonym: Sez_0741

Alternate gene names: 195977873

Gene position: 773887-775671 (Clockwise)

Preceding gene: 195977871

Following gene: 195977874

Centisome position: 38.23

GC content: 41.85

Gene sequence:

>1785_bases
ATGAAGCAGTTTTGCGTAAAGGAGCAGTTTTACCTTGATGGCAAGCCGTTTAAGATATTATCAGGTGCCATTCATTACTT
TAGAATAGCTCCTGATAGCTGGCCTAGGGTGCTTTATCAGCTGAAAGCCTTAGGCTTTAATACAGTAGAAACCTATATTC
CTTGGAACATGCATGAGCCAAGGAAGGGACAGTTTACCTTTGAGGGGATTGCAGATGTTGAGGCGTTTTTGGATTTGGCA
CAGGAATATGGTCTATATGCTATTGTCAGACCTTCACCTTATATCTGTGCTGAATGGGAATTTGGTGGTTTGCCTGCTTG
GCTATTAACTGAAAATTGTCGTGTCAGATCAAGCGATGAGGTCTTTCTTAAGCATGTATCAGATTATTATGATGTGTTAC
TACCAAAGCTGGTGAAGCGTCAGTTAGATAATGGCGGCAATATTCTGATGTTTCAGCTTGAAAATGAGTATGGTTCTTAT
GGTGAAGAAAAGGATTATTTAAGAAAATTAAAAGAGCTTATGCTTGCTAAAGGCATTAGTGCCCCTCTTTTCACCTCAGA
TGGACCTTGGTTAGCCACGCTAGCATCAGGAAGTTTGATTGATGATGATGTTTTTGTGACAGGCAACTTTGGGTCAAACG
CTTCAAAACAATTTGCCAGCATGCAGGATTTTTTCCAAGCACATCAAAAGCAATGGCCTCTGATGTGTATGGAATTCTGG
TTGGGCTGGTTTAATCGCTGGAATGAGCCAATCATTCGAAGGGACCCCAAGGAAGCTGTTGATGCAATCATGGAAGCTAT
AGAGCTAGGCAGCATTAACCTTTATATGTTTTGTGGTGGCACTAATTTTGGCTTTATGAATGGCTCGTCAGCTCGTCTGC
AAAAGGATTTACCACAGATAACCTCCTATGATTACGACGCATTACTAGATGAGGCAGGAAACCCAACGAAGAAATATATC
CTGCTACAAGAACGTCTCAAGGAGCGTTACCCCCAATTATCCTTTGCAGAGCCAATGACCAGTCCTACGATGGCCTTAGA
GTCTATCAAGTTGTCGGCAAGGGTTAGTCTTTTTAAGACAATCAAAAATGTAAGCGCTCTTAAGAAGAGCTTTTATCCCT
GCAATATGGAGGAGCTAGATCAACCAACGGGCTACCTACTGTATAGAACGCACCTCGCTAGACATAGCAAGGAGGAGCGG
CTCAGGGTCATTGATGCTAGAGACCGCATTCAGCTCTTTTTAGATGAAAAGCACGTGAAAACCCAGTATCAGGAGGAAAT
CGGTCAGGATATACTGATACACCAAGAAGACGAGACCACACAGCTTGATCTTTTAGTTGAAAATATGGGACGTGTCAGCT
ATGGGCATAAGCTAACAGCACCAAGTCAACAAAAAGGATTAGGCAGAGGCTTAATGGCTGACTTGCATTTTGTAGGTCAT
TGGGAGCATTTTCTGCTAGATTTTCAAGAGCTGGATTGGATTGATTTTTCTGCAGGCTGGACTGATGGGGTGCCAGGATT
TTACGCCTATGATTTTGATTGTCAGCAGCCGGCAGATACCTATCTTGATTTGAGTCAATTCGGAAAAGGAATTGCCCTTG
TAAATGGTGTTAACCTAGGACGTTTTTGGAAGGTCGGTCCAACATTATCGCTTTATATTCCTAAGGGATTATTAAAGCAA
GGTCAAAATAGACTGCTGATATTTGAAACCGAAGGGCAGTTTAGTGAGTCAATTCGTTTAACTAAGGAACCAATTTATAA
TGATATAAAAGGAGAAAACTTATGA

Upstream 100 bases:

>100_bases
AAATAGCAAGCTGATGTCATATCTTACCAGTTATTGCTCAGATAGCTTGTCAATCAGTCATTGATCAAAGGCTGATGGTT
AATGAATAAAAGGAGATAAT

Downstream 100 bases:

>100_bases
CAATTGTTGCAGCACGTATTGACGGCCGGTTAATTCATGGTCAGGTAGCTAATCTATGGACGACAAAGCTAAACATTAGC
CGTATCATGGTGGTCGATAA

Product: beta-galactosidase precursor Bga

Products: NA

Alternate protein names: Lactase [H]

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MKQFCVKEQFYLDGKPFKILSGAIHYFRIAPDSWPRVLYQLKALGFNTVETYIPWNMHEPRKGQFTFEGIADVEAFLDLA
QEYGLYAIVRPSPYICAEWEFGGLPAWLLTENCRVRSSDEVFLKHVSDYYDVLLPKLVKRQLDNGGNILMFQLENEYGSY
GEEKDYLRKLKELMLAKGISAPLFTSDGPWLATLASGSLIDDDVFVTGNFGSNASKQFASMQDFFQAHQKQWPLMCMEFW
LGWFNRWNEPIIRRDPKEAVDAIMEAIELGSINLYMFCGGTNFGFMNGSSARLQKDLPQITSYDYDALLDEAGNPTKKYI
LLQERLKERYPQLSFAEPMTSPTMALESIKLSARVSLFKTIKNVSALKKSFYPCNMEELDQPTGYLLYRTHLARHSKEER
LRVIDARDRIQLFLDEKHVKTQYQEEIGQDILIHQEDETTQLDLLVENMGRVSYGHKLTAPSQQKGLGRGLMADLHFVGH
WEHFLLDFQELDWIDFSAGWTDGVPGFYAYDFDCQQPADTYLDLSQFGKGIALVNGVNLGRFWKVGPTLSLYIPKGLLKQ
GQNRLLIFETEGQFSESIRLTKEPIYNDIKGENL

Sequences:

>Translated_594_residues
MKQFCVKEQFYLDGKPFKILSGAIHYFRIAPDSWPRVLYQLKALGFNTVETYIPWNMHEPRKGQFTFEGIADVEAFLDLA
QEYGLYAIVRPSPYICAEWEFGGLPAWLLTENCRVRSSDEVFLKHVSDYYDVLLPKLVKRQLDNGGNILMFQLENEYGSY
GEEKDYLRKLKELMLAKGISAPLFTSDGPWLATLASGSLIDDDVFVTGNFGSNASKQFASMQDFFQAHQKQWPLMCMEFW
LGWFNRWNEPIIRRDPKEAVDAIMEAIELGSINLYMFCGGTNFGFMNGSSARLQKDLPQITSYDYDALLDEAGNPTKKYI
LLQERLKERYPQLSFAEPMTSPTMALESIKLSARVSLFKTIKNVSALKKSFYPCNMEELDQPTGYLLYRTHLARHSKEER
LRVIDARDRIQLFLDEKHVKTQYQEEIGQDILIHQEDETTQLDLLVENMGRVSYGHKLTAPSQQKGLGRGLMADLHFVGH
WEHFLLDFQELDWIDFSAGWTDGVPGFYAYDFDCQQPADTYLDLSQFGKGIALVNGVNLGRFWKVGPTLSLYIPKGLLKQ
GQNRLLIFETEGQFSESIRLTKEPIYNDIKGENL
>Mature_594_residues
MKQFCVKEQFYLDGKPFKILSGAIHYFRIAPDSWPRVLYQLKALGFNTVETYIPWNMHEPRKGQFTFEGIADVEAFLDLA
QEYGLYAIVRPSPYICAEWEFGGLPAWLLTENCRVRSSDEVFLKHVSDYYDVLLPKLVKRQLDNGGNILMFQLENEYGSY
GEEKDYLRKLKELMLAKGISAPLFTSDGPWLATLASGSLIDDDVFVTGNFGSNASKQFASMQDFFQAHQKQWPLMCMEFW
LGWFNRWNEPIIRRDPKEAVDAIMEAIELGSINLYMFCGGTNFGFMNGSSARLQKDLPQITSYDYDALLDEAGNPTKKYI
LLQERLKERYPQLSFAEPMTSPTMALESIKLSARVSLFKTIKNVSALKKSFYPCNMEELDQPTGYLLYRTHLARHSKEER
LRVIDARDRIQLFLDEKHVKTQYQEEIGQDILIHQEDETTQLDLLVENMGRVSYGHKLTAPSQQKGLGRGLMADLHFVGH
WEHFLLDFQELDWIDFSAGWTDGVPGFYAYDFDCQQPADTYLDLSQFGKGIALVNGVNLGRFWKVGPTLSLYIPKGLLKQ
GQNRLLIFETEGQFSESIRLTKEPIYNDIKGENL

Specific function: Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages [H]

COG id: COG1874

COG function: function code G; Beta-galactosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 35 family [H]

Homologues:

Organism=Homo sapiens, GI164519026, Length=600, Percent_Identity=35.6666666666667, Blast_Score=326, Evalue=5e-89,
Organism=Homo sapiens, GI31543093, Length=591, Percent_Identity=35.7021996615905, Blast_Score=321, Evalue=1e-87,
Organism=Homo sapiens, GI119372312, Length=604, Percent_Identity=35.0993377483444, Blast_Score=303, Evalue=2e-82,
Organism=Homo sapiens, GI119372308, Length=604, Percent_Identity=35.0993377483444, Blast_Score=303, Evalue=3e-82,
Organism=Homo sapiens, GI40255043, Length=604, Percent_Identity=34.7682119205298, Blast_Score=291, Evalue=1e-78,
Organism=Homo sapiens, GI208022658, Length=394, Percent_Identity=29.6954314720812, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI72000600, Length=596, Percent_Identity=34.2281879194631, Blast_Score=303, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17568491, Length=611, Percent_Identity=28.4779050736498, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24582088, Length=597, Percent_Identity=36.5159128978224, Blast_Score=336, Evalue=2e-92,
Organism=Drosophila melanogaster, GI24646169, Length=616, Percent_Identity=33.6038961038961, Blast_Score=317, Evalue=2e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR019801
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR001944 [H]

Pfam domain/function: PF01301 Glyco_hydro_35 [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 68330; Mature: 68330

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQFCVKEQFYLDGKPFKILSGAIHYFRIAPDSWPRVLYQLKALGFNTVETYIPWNMHEP
CCCCCCCHHEEECCCCHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCHHEEECCCCCCC
RKGQFTFEGIADVEAFLDLAQEYGLYAIVRPSPYICAEWEFGGLPAWLLTENCRVRSSDE
CCCCEEECHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCCCCCCEEECCCCCCCCCHH
VFLKHVSDYYDVLLPKLVKRQLDNGGNILMFQLENEYGSYGEEKDYLRKLKELMLAKGIS
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC
APLFTSDGPWLATLASGSLIDDDVFVTGNFGSNASKQFASMQDFFQAHQKQWPLMCMEFW
CCCEECCCCEEEEECCCCEECCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
LGWFNRWNEPIIRRDPKEAVDAIMEAIELGSINLYMFCGGTNFGFMNGSSARLQKDLPQI
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHCHHH
TSYDYDALLDEAGNPTKKYILLQERLKERYPQLSFAEPMTSPTMALESIKLSARVSLFKT
HCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IKNVSALKKSFYPCNMEELDQPTGYLLYRTHLARHSKEERLRVIDARDRIQLFLDEKHVK
HHHHHHHHHHCCCCCHHHCCCCCCEEEEEHHHHHCCHHHHEEEECCCCCEEEEECHHHHH
TQYQEEIGQDILIHQEDETTQLDLLVENMGRVSYGHKLTAPSQQKGLGRGLMADLHFVGH
HHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHC
WEHFLLDFQELDWIDFSAGWTDGVPGFYAYDFDCQQPADTYLDLSQFGKGIALVNGVNLG
HHHHHHHHHHCCEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCC
RFWKVGPTLSLYIPKGLLKQGQNRLLIFETEGQFSESIRLTKEPIYNDIKGENL
CEEECCCEEEEEECHHHHHCCCCCEEEEECCCCCCHHHCCCHHHHCCCCCCCCC
>Mature Secondary Structure
MKQFCVKEQFYLDGKPFKILSGAIHYFRIAPDSWPRVLYQLKALGFNTVETYIPWNMHEP
CCCCCCCHHEEECCCCHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCHHEEECCCCCCC
RKGQFTFEGIADVEAFLDLAQEYGLYAIVRPSPYICAEWEFGGLPAWLLTENCRVRSSDE
CCCCEEECHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCCCCCCEEECCCCCCCCCHH
VFLKHVSDYYDVLLPKLVKRQLDNGGNILMFQLENEYGSYGEEKDYLRKLKELMLAKGIS
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC
APLFTSDGPWLATLASGSLIDDDVFVTGNFGSNASKQFASMQDFFQAHQKQWPLMCMEFW
CCCEECCCCEEEEECCCCEECCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
LGWFNRWNEPIIRRDPKEAVDAIMEAIELGSINLYMFCGGTNFGFMNGSSARLQKDLPQI
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHCHHH
TSYDYDALLDEAGNPTKKYILLQERLKERYPQLSFAEPMTSPTMALESIKLSARVSLFKT
HCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IKNVSALKKSFYPCNMEELDQPTGYLLYRTHLARHSKEERLRVIDARDRIQLFLDEKHVK
HHHHHHHHHHCCCCCHHHCCCCCCEEEEEHHHHHCCHHHHEEEECCCCCEEEEECHHHHH
TQYQEEIGQDILIHQEDETTQLDLLVENMGRVSYGHKLTAPSQQKGLGRGLMADLHFVGH
HHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHC
WEHFLLDFQELDWIDFSAGWTDGVPGFYAYDFDCQQPADTYLDLSQFGKGIALVNGVNLG
HHHHHHHHHHCCEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCC
RFWKVGPTLSLYIPKGLLKQGQNRLLIFETEGQFSESIRLTKEPIYNDIKGENL
CEEECCCEEEEEECHHHHHCCCCCEEEEECCCCCCHHHCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8563148 [H]