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The map label for this gene is inlA [H]

Identifier: 195977813

GI number: 195977813

Start: 703060

End: 705300

Strand: Direct

Name: inlA [H]

Synonym: Sez_0679

Alternate gene names: 195977813

Gene position: 703060-705300 (Clockwise)

Preceding gene: 195977811

Following gene: 195977814

Centisome position: 34.73

GC content: 42.12

Gene sequence:

>2241_bases
ATGAAAAGTAAAAAATTAATGCTAATGGCTAGCCTGTTTATGGCTTGTCACCTGCCCCTGACAGCTTGTCAGTCGACAAA
GCAGCAAACAAATCAGCCTAAGACAAAACAGACAGCTAAAAAAGCGACCAAAAAGAAACAGTCTAAAAAGGTTAAGCAAA
CAAGAAAAGACCGTAAGGGAGTAGCGGGGATTGACTTTCCAACTGATGACGGTTTTATCTTGACCAAGGATTCAAAAATC
TTATCTAGAACAGAAAACGGTATTGTTGTTGAGCATAATGGGCATTCGCATTTTATCTTTTATGCAGACCTCAAGGGCAG
TAAGTTTGAGTACCTGATTCCAAAAGACGCTGACCTAAATAAGCCTGAGCAGACCAAGGCAGCATCAGGTCATCACCATA
CTAGTGCTAATGACCCGCACCATCACTATGTGTTTAACCCAGCTGATATTGTAGCTGAGGACGCCTTAGGCTATATTGTC
CGTCATGGGGATCATTATCACTATATTCTAAAAAGCTCACTAGGTGGTCAGGTAGCCTACCCAGTGCCTAATCATGTGCC
GCTGTCAAATCCATCATCACCAGCTGGAAAATTTGCAGGTGTTGATTACCCAACTAGCGACGGCTTCTTATTTGATGGTA
CAGGGATTGTCGGTCGAACATCTTATGGCTTGATTGTTGACCACAATGGGCACAATCATTTAGTCACTTATGAAAGCCTG
CGTCACAGTAAGTGGAAGCATTTAATTGAAACACCAAAGGAAGAGGCACCGGCTAAGCCTGAAAGTGATCTTGAGAAAAC
AATCGCTTTGAAAAAAGCACATTTGGCTAAGTCATTAAATATTCCTGAGGACAGCATTCGTGTGGAGCATACAGAAGAAG
GTGTCATTCTTGACTATCCACATGGTGACCACCGTCATGCGACCTATATTGATGACATTGATTTATCAAAGCCATTTGAC
CCACATGCAGTAGATCCACATGCCAAGGATAGGATTGGTATGGCAACCTTGAGAAAGCTTGGCTTTGATGAGGAAGTCAT
TTCATCAATTATTCACGCCAGTGCGCCAACTGAGTTTCCATCAAGAGAACGAGACTTAGAGAAAATGAAGGCATGGTTGG
CGACTATTGAGTATCTCAATATTGGTGAAATCAAGGATCCTCTTAAGCGGGCAGGTCTAAACCTGATGCCTAATATACAG
ATTTTAGGTATTGGCTTTACACCAATTACTGATATTACACCGGTCTACCAGTTTAAGAACCTCAAACAATTGTGGATGAC
AAAGACTGGCATTACTAATTATGATTTCTTGAAGAACCTGCCAACACTTGAAGGAATTGACATTTCTCAAAATGGTGTTT
CTGACCTGAGCTTCCTTAAAGCCTTTCCACATTACAAGGTGATTTCGGCAGCAGGAAATGATATCACAGATATTTCTATT
TTGAAGGAATTGCCAAACCTAGAATCCGTTAACCTTGACTTTAACAAGATTACAGACATTTCTGCCTTGGCAAATGCTCA
AAAGCTAGTCGCTGTCAGCCTAGAGCACAATCAGATCAAGGATTTGGGTGCCTTATCACACAAGGGGCAATTGACCAAAC
TCTTTGTGTCAGACAATCCTGACCTTGATTTGTCAACGCTAAAATCCTCTGCACTTAAGGAAATTACTGCCAAGGAGGTT
AATTTACAAAGCCTTAGCTTTGTTAAGGACTTACCGGCGTTAGAGCAGCTAGTGGTTGACCAAAACAAGCTTAACAGCTT
GACAGGCCTTGAGCAAAATAAGAGCCTGATTCAGCTATCAGCTAACCAGAACATGATTAATAGCTTGGCCTTACCAGGTA
CACAAAATTCCTTGCAATCACTTAATCTTGAGGAGAATCAGCTGACTAATTTTGAGGGTGTGAATAGCTATCTAGCCCTA
GAGTCAATCAATGTTAATCGCAACAAGATCAATACTTTAGCCTTGAAGGAGCCTAATCAAACGCTGAAATACATTCAGGC
TGATGGTAATCACTTCCCAGCTGAGGAGCTAGCTGCTGAACAAGGACAATTCCCACAAGGAATTATCAAGAACTTCAAAG
CAGCAGAGGGTGGTAGTCTAAATAATGCTACGCCAGCAGCAGAACCTGCTCAAGACGAGCATAAACAGGCTGATACCGAT
CATGAGGAAGCAGATAGCCATGATCACGAGACAGCTGATGAGCATCATGATCATGACCACGATGACCATCATCATGGCTA
A

Upstream 100 bases:

>100_bases
GAGAATGAATTAAAAATAAGAAAACAGTTGAAATCATTTGTTTTTTTGGTATAATTAACTAGTTAATATCTTATTTAACT
AGTTAATTTATGGAGGAAAG

Downstream 100 bases:

>100_bases
TGACGGCTAGTGCTGATCATTACCGAAATAAGAGGGGGATACGGCTGCTGAGGTAGCTTGGCTGTATTCCTTTTCTTGTT
TTTTGATGAAAAAGCTTAAA

Product: internalin A precursor InlA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 746; Mature: 746

Protein sequence:

>746_residues
MKSKKLMLMASLFMACHLPLTACQSTKQQTNQPKTKQTAKKATKKKQSKKVKQTRKDRKGVAGIDFPTDDGFILTKDSKI
LSRTENGIVVEHNGHSHFIFYADLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
RHGDHYHYILKSSLGGQVAYPVPNHVPLSNPSSPAGKFAGVDYPTSDGFLFDGTGIVGRTSYGLIVDHNGHNHLVTYESL
RHSKWKHLIETPKEEAPAKPESDLEKTIALKKAHLAKSLNIPEDSIRVEHTEEGVILDYPHGDHRHATYIDDIDLSKPFD
PHAVDPHAKDRIGMATLRKLGFDEEVISSIIHASAPTEFPSRERDLEKMKAWLATIEYLNIGEIKDPLKRAGLNLMPNIQ
ILGIGFTPITDITPVYQFKNLKQLWMTKTGITNYDFLKNLPTLEGIDISQNGVSDLSFLKAFPHYKVISAAGNDITDISI
LKELPNLESVNLDFNKITDISALANAQKLVAVSLEHNQIKDLGALSHKGQLTKLFVSDNPDLDLSTLKSSALKEITAKEV
NLQSLSFVKDLPALEQLVVDQNKLNSLTGLEQNKSLIQLSANQNMINSLALPGTQNSLQSLNLEENQLTNFEGVNSYLAL
ESINVNRNKINTLALKEPNQTLKYIQADGNHFPAEELAAEQGQFPQGIIKNFKAAEGGSLNNATPAAEPAQDEHKQADTD
HEEADSHDHETADEHHDHDHDDHHHG

Sequences:

>Translated_746_residues
MKSKKLMLMASLFMACHLPLTACQSTKQQTNQPKTKQTAKKATKKKQSKKVKQTRKDRKGVAGIDFPTDDGFILTKDSKI
LSRTENGIVVEHNGHSHFIFYADLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
RHGDHYHYILKSSLGGQVAYPVPNHVPLSNPSSPAGKFAGVDYPTSDGFLFDGTGIVGRTSYGLIVDHNGHNHLVTYESL
RHSKWKHLIETPKEEAPAKPESDLEKTIALKKAHLAKSLNIPEDSIRVEHTEEGVILDYPHGDHRHATYIDDIDLSKPFD
PHAVDPHAKDRIGMATLRKLGFDEEVISSIIHASAPTEFPSRERDLEKMKAWLATIEYLNIGEIKDPLKRAGLNLMPNIQ
ILGIGFTPITDITPVYQFKNLKQLWMTKTGITNYDFLKNLPTLEGIDISQNGVSDLSFLKAFPHYKVISAAGNDITDISI
LKELPNLESVNLDFNKITDISALANAQKLVAVSLEHNQIKDLGALSHKGQLTKLFVSDNPDLDLSTLKSSALKEITAKEV
NLQSLSFVKDLPALEQLVVDQNKLNSLTGLEQNKSLIQLSANQNMINSLALPGTQNSLQSLNLEENQLTNFEGVNSYLAL
ESINVNRNKINTLALKEPNQTLKYIQADGNHFPAEELAAEQGQFPQGIIKNFKAAEGGSLNNATPAAEPAQDEHKQADTD
HEEADSHDHETADEHHDHDHDDHHHG
>Mature_746_residues
MKSKKLMLMASLFMACHLPLTACQSTKQQTNQPKTKQTAKKATKKKQSKKVKQTRKDRKGVAGIDFPTDDGFILTKDSKI
LSRTENGIVVEHNGHSHFIFYADLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
RHGDHYHYILKSSLGGQVAYPVPNHVPLSNPSSPAGKFAGVDYPTSDGFLFDGTGIVGRTSYGLIVDHNGHNHLVTYESL
RHSKWKHLIETPKEEAPAKPESDLEKTIALKKAHLAKSLNIPEDSIRVEHTEEGVILDYPHGDHRHATYIDDIDLSKPFD
PHAVDPHAKDRIGMATLRKLGFDEEVISSIIHASAPTEFPSRERDLEKMKAWLATIEYLNIGEIKDPLKRAGLNLMPNIQ
ILGIGFTPITDITPVYQFKNLKQLWMTKTGITNYDFLKNLPTLEGIDISQNGVSDLSFLKAFPHYKVISAAGNDITDISI
LKELPNLESVNLDFNKITDISALANAQKLVAVSLEHNQIKDLGALSHKGQLTKLFVSDNPDLDLSTLKSSALKEITAKEV
NLQSLSFVKDLPALEQLVVDQNKLNSLTGLEQNKSLIQLSANQNMINSLALPGTQNSLQSLNLEENQLTNFEGVNSYLAL
ESINVNRNKINTLALKEPNQTLKYIQADGNHFPAEELAAEQGQFPQGIIKNFKAAEGGSLNNATPAAEPAQDEHKQADTD
HEEADSHDHETADEHHDHDHDDHHHG

Specific function: Unknown. A role in virulence could not be demonstrated [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 3 MucBP domains [H]

Homologues:

Organism=Homo sapiens, GI21389483, Length=206, Percent_Identity=25.2427184466019, Blast_Score=67, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17554124, Length=220, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR000601
- InterPro:   IPR001899 [H]

Pfam domain/function: PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 82705; Mature: 82705

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKKLMLMASLFMACHLPLTACQSTKQQTNQPKTKQTAKKATKKKQSKKVKQTRKDRKG
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
VAGIDFPTDDGFILTKDSKILSRTENGIVVEHNGHSHFIFYADLKGSKFEYLIPKDADLN
CCCCCCCCCCCEEEECCCHHHHHCCCCEEEEECCCEEEEEEEECCCCEEEEECCCCCCCC
KPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIVRHGDHYHYILKSSLGGQVAY
CCHHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEC
PVPNHVPLSNPSSPAGKFAGVDYPTSDGFLFDGTGIVGRTSYGLIVDHNGHNHLVTYESL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEECCCEEEEEECCCCCCEEEHHHH
RHSKWKHLIETPKEEAPAKPESDLEKTIALKKAHLAKSLNIPEDSIRVEHTEEGVILDYP
HHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCEEEECC
HGDHRHATYIDDIDLSKPFDPHAVDPHAKDRIGMATLRKLGFDEEVISSIIHASAPTEFP
CCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCC
SRERDLEKMKAWLATIEYLNIGEIKDPLKRAGLNLMPNIQILGIGFTPITDITPVYQFKN
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHH
LKQLWMTKTGITNYDFLKNLPTLEGIDISQNGVSDLSFLKAFPHYKVISAAGNDITDISI
HHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHH
LKELPNLESVNLDFNKITDISALANAQKLVAVSLEHNQIKDLGALSHKGQLTKLFVSDNP
HHHCCCCCEECCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCEEEEEECCCC
DLDLSTLKSSALKEITAKEVNLQSLSFVKDLPALEQLVVDQNKLNSLTGLEQNKSLIQLS
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCEEEEE
ANQNMINSLALPGTQNSLQSLNLEENQLTNFEGVNSYLALESINVNRNKINTLALKEPNQ
CCCCHHHHHCCCCCCHHHHHCCCCHHHCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCC
TLKYIQADGNHFPAEELAAEQGQFPQGIIKNFKAAEGGSLNNATPAAEPAQDEHKQADTD
EEHEEECCCCCCCHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCC
HEEADSHDHETADEHHDHDHDDHHHG
HHHCCCCCCCCCHHCCCCCCCCCCCC
>Mature Secondary Structure
MKSKKLMLMASLFMACHLPLTACQSTKQQTNQPKTKQTAKKATKKKQSKKVKQTRKDRKG
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
VAGIDFPTDDGFILTKDSKILSRTENGIVVEHNGHSHFIFYADLKGSKFEYLIPKDADLN
CCCCCCCCCCCEEEECCCHHHHHCCCCEEEEECCCEEEEEEEECCCCEEEEECCCCCCCC
KPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIVRHGDHYHYILKSSLGGQVAY
CCHHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEC
PVPNHVPLSNPSSPAGKFAGVDYPTSDGFLFDGTGIVGRTSYGLIVDHNGHNHLVTYESL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEECCCEEEEEECCCCCCEEEHHHH
RHSKWKHLIETPKEEAPAKPESDLEKTIALKKAHLAKSLNIPEDSIRVEHTEEGVILDYP
HHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCEEEECC
HGDHRHATYIDDIDLSKPFDPHAVDPHAKDRIGMATLRKLGFDEEVISSIIHASAPTEFP
CCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCC
SRERDLEKMKAWLATIEYLNIGEIKDPLKRAGLNLMPNIQILGIGFTPITDITPVYQFKN
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHH
LKQLWMTKTGITNYDFLKNLPTLEGIDISQNGVSDLSFLKAFPHYKVISAAGNDITDISI
HHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHH
LKELPNLESVNLDFNKITDISALANAQKLVAVSLEHNQIKDLGALSHKGQLTKLFVSDNP
HHHCCCCCEECCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCEEEEEECCCC
DLDLSTLKSSALKEITAKEVNLQSLSFVKDLPALEQLVVDQNKLNSLTGLEQNKSLIQLS
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCEEEEE
ANQNMINSLALPGTQNSLQSLNLEENQLTNFEGVNSYLALESINVNRNKINTLALKEPNQ
CCCCHHHHHCCCCCCHHHHHCCCCHHHCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCC
TLKYIQADGNHFPAEELAAEQGQFPQGIIKNFKAAEGGSLNNATPAAEPAQDEHKQADTD
EEHEEECCCCCCCHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCC
HEEADSHDHETADEHHDHDHDDHHHG
HHHCCCCCCCCCHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]