| Definition | Streptococcus equi subsp. zooepidemicus MGCS10565, complete genome. |
|---|---|
| Accession | NC_011134 |
| Length | 2,024,171 |
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The map label for this gene is murF [H]
Identifier: 195977779
GI number: 195977779
Start: 663012
End: 664376
Strand: Direct
Name: murF [H]
Synonym: Sez_0643
Alternate gene names: 195977779
Gene position: 663012-664376 (Clockwise)
Preceding gene: 195977778
Following gene: 195977780
Centisome position: 32.75
GC content: 44.32
Gene sequence:
>1365_bases GTGGCAAGAGTTGTTGATGCTCAAAATAGTCTTTCTGATTTAGACGACGTTCCTCTGAATCAGATTGAATTTGACAGTAG AAACATCACAAAAGGTGATCTTTTTTTACCGCTACAGGGTGAGCGAGATGGCCATGATTTTATTGACTTAGCCTTTGAAA ATGGGGCCGTAGCTACCTTTTCAGAAAGAGCAATCAGTGGCAGGCCTTATATACTAGTTGAGAATTGCTTGGCCGCTTTT CAAAAATTAGCCCAGTATTATATTGATAAGCTACGTGTCGACGTCATTGCTGTAACAGGCTCAAACGGTAAAACATCAAC CAAGGATATGATTGAAGCAGTCCTGGCAAAAGCTTATAAGACCTACAAAACCCAGGGCAATTATAATAATGACATTGGCT TGCCTTATACGGTGCTTCACATGCCAGAGGATACTGAGAAGATTGTTCTAGAGATGGGGCAGGATCATATGGGAGATATT CAGCTGCTCTCTAGAATTGCGAGACCTCATATTGCAGTGCTAACCCTTATTGGTGAGGCTCACTTAGCCTACTTTGGTTC TCGCGAGAAGATTGCCGAGGGAAAAATGCAAATCGTTGATGGGATGGACTCTAACGGGATTTTAATTGCTCCTGGTGATC CTATCCTTGATCCATATTTGCCGGATAGTCAGATGGTCATTCGCTTTGGCGATCATCAAGAGCTGGTGGTTGAGGATATC AAAGAGCGCAAGGACTCCTTGACCTTTAAGACTAATGTCTTACCAAGACCGGTCACTATTCCCTTAACTGGAAAATACAA TGCAACCAATGCTATGATAGCAGCCTATGTCGGCAGGCTCTTGGCTGTGCCTGATGAGGACATTATAGAAGCTCTAGAAG CAGTCAAGCTGACACGCCACCGAACCGAGTGGATCAAGGCGGCTAATGGCGCCGACCTTTTGGCGGATGTGTATAATGCT AATCCAACTGCTATGCGGTTAATTTTGGAAACCTTTGCTGCCATTCCGGCCAACCTTAATGGCAAAAAAATAGCTGTTTT AGCTGATATGAAGGAATTAGGCGCTGACTCAGTTGCTTTGCATTCTCAGCTGATTACCAGCTTAGACCCCAAGCGTATTG ATCAATTGGTCTTTTACGGTGATGATATTCAAGCCTTGGCCAAGCTAGCTAGTCAAGATTATCCAAGTGGCAGAGTTAGC TTCTTTAAAAAGAATAATCAAGAGGATCAATACGAGGACATGTGCCAGTACCTGTTGACTATTCTTGAGCCTAATGACCA GATGCTGCTAAAGGGCAGCCACTCCATGCTGCTAGCAAATGTGGTTGATCGCCTGACAGCTCCTCATGCTGGGAAGTCCT CCTAA
Upstream 100 bases:
>100_bases ATAGAAAGAATATTCCTAATATGTTATGCTATAATATAAGCAAAGCTTTAAAAACCAGTGTTTTAAGAGGAAAAATAAGA TGAAATTAACATTACATGAA
Downstream 100 bases:
>100_bases CACTTTTTCAGAAAAAACACATGAAACATCTTGTCCTCTCATTAAGATTAAGGTATAATGAAAAAATGTAGAAAGGGATG TTTATGAATTTTTTTGCAAT
Product: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase MurF
Products: NA
Alternate protein names: D-alanyl-D-alanine-adding enzyme; UDP-MurNAc-pentapeptide synthetase [H]
Number of amino acids: Translated: 454; Mature: 453
Protein sequence:
>454_residues MARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLPLQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAF QKLAQYYIDKLRVDVIAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMGQDHMGDI QLLSRIARPHIAVLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAPGDPILDPYLPDSQMVIRFGDHQELVVEDI KERKDSLTFKTNVLPRPVTIPLTGKYNATNAMIAAYVGRLLAVPDEDIIEALEAVKLTRHRTEWIKAANGADLLADVYNA NPTAMRLILETFAAIPANLNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQALAKLASQDYPSGRVS FFKKNNQEDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVDRLTAPHAGKSS
Sequences:
>Translated_454_residues MARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLPLQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAF QKLAQYYIDKLRVDVIAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMGQDHMGDI QLLSRIARPHIAVLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAPGDPILDPYLPDSQMVIRFGDHQELVVEDI KERKDSLTFKTNVLPRPVTIPLTGKYNATNAMIAAYVGRLLAVPDEDIIEALEAVKLTRHRTEWIKAANGADLLADVYNA NPTAMRLILETFAAIPANLNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQALAKLASQDYPSGRVS FFKKNNQEDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVDRLTAPHAGKSS >Mature_453_residues ARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLPLQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAFQ KLAQYYIDKLRVDVIAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMGQDHMGDIQ LLSRIARPHIAVLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAPGDPILDPYLPDSQMVIRFGDHQELVVEDIK ERKDSLTFKTNVLPRPVTIPLTGKYNATNAMIAAYVGRLLAVPDEDIIEALEAVKLTRHRTEWIKAANGADLLADVYNAN PTAMRLILETFAAIPANLNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQALAKLASQDYPSGRVSF FKKNNQEDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVDRLTAPHAGKSS
Specific function: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein [H]
COG id: COG0770
COG function: function code M; UDP-N-acetylmuramyl pentapeptide synthase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family [H]
Homologues:
Organism=Escherichia coli, GI1786274, Length=443, Percent_Identity=31.8284424379233, Blast_Score=169, Evalue=4e-43,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR005863 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.10 [H]
Molecular weight: Translated: 50191; Mature: 50060
Theoretical pI: Translated: 4.81; Mature: 4.81
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLPLQGERDGHDFIDLAFENGAVATF CCCEECCCCCHHHHCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCEEEEEECCCCEEEE SERAISGRPYILVENCLAAFQKLAQYYIDKLRVDVIAVTGSNGKTSTKDMIEAVLAKAYK HHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHH TYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMGQDHMGDIQLLSRIARPHIAVLTLIGEA HHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHCCCCEEEHHHHHHH HLAYFGSREKIAEGKMQIVDGMDSNGILIAPGDPILDPYLPDSQMVIRFGDHQELVVEDI HHHHCCCHHHHHCCCEEEECCCCCCCEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHH KERKDSLTFKTNVLPRPVTIPLTGKYNATNAMIAAYVGRLLAVPDEDIIEALEAVKLTRH HHHHHCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH RTEWIKAANGADLLADVYNANPTAMRLILETFAAIPANLNGKKIAVLADMKELGADSVAL HHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHCCCCHHHH HSQLITSLDPKRIDQLVFYGDDIQALAKLASQDYPSGRVSFFKKNNQEDQYEDMCQYLLT HHHHHHCCCHHHHHHHEEECCCHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHH ILEPNDQMLLKGSHSMLLANVVDRLTAPHAGKSS HHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCC >Mature Secondary Structure ARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLPLQGERDGHDFIDLAFENGAVATF CCEECCCCCHHHHCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCEEEEEECCCCEEEE SERAISGRPYILVENCLAAFQKLAQYYIDKLRVDVIAVTGSNGKTSTKDMIEAVLAKAYK HHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHH TYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMGQDHMGDIQLLSRIARPHIAVLTLIGEA HHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHCCCCEEEHHHHHHH HLAYFGSREKIAEGKMQIVDGMDSNGILIAPGDPILDPYLPDSQMVIRFGDHQELVVEDI HHHHCCCHHHHHCCCEEEECCCCCCCEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHH KERKDSLTFKTNVLPRPVTIPLTGKYNATNAMIAAYVGRLLAVPDEDIIEALEAVKLTRH HHHHHCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH RTEWIKAANGADLLADVYNANPTAMRLILETFAAIPANLNGKKIAVLADMKELGADSVAL HHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHCCCCHHHH HSQLITSLDPKRIDQLVFYGDDIQALAKLASQDYPSGRVSFFKKNNQEDQYEDMCQYLLT HHHHHHCCCHHHHHHHEEECCCHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHH ILEPNDQMLLKGSHSMLLANVVDRLTAPHAGKSS HHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]