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The map label for this gene is gpmA

Identifier: 195977771

GI number: 195977771

Start: 655424

End: 656119

Strand: Direct

Name: gpmA

Synonym: Sez_0635

Alternate gene names: 195977771

Gene position: 655424-656119 (Clockwise)

Preceding gene: 195977770

Following gene: 195977772

Centisome position: 32.38

GC content: 43.39

Gene sequence:

>696_bases
ATGGTAAAATTGGTTTTCGCTCGTCATGGTGAGTCAGAATGGAACAAAGCAAACCTTTTCACTGGTTGGGCTGACGTTGA
TTTGTCCGAAAAGGGAACACAGCAGGCTATTGATGCTGGAAAATTGATCAAGGAAGCTGGTATTGCATTTGATCTTGCCT
TTACATCTGTGCTTAAGCGTGCTATCAAGACAACTAATCTTGCACTTGAGTATTCTGATCAGCTTTGGGTACCTGTTGAA
AAATCATGGCGCTTGAACGAGCGTCACTATGGCGGCTTGACTGGTAAAAACAAGGCAGAAGCAGCTGAGCAATTTGGTGA
TGAGCAGGTTCATATCTGGCGCCGTTCATATGATGTGTTGCCTCCTGATATGGCTAAGGATGATGAGCATTCAGCACATA
CTGATCGTCGTTACGCTCATCTTGATCATTCTGTTATTCCAGATGCAGAAAACCTGAAGGTGACACTAGAGCGTGCTCTT
CCTTTCTGGGAGGATAAGATTGCACCAGCCTTAGTTGATGGTAAAAATGTTTTTGTTGGAGCACATGGTAACTCTATTCG
TGCCCTTGTCAAACACATCAAGCAATTATCAGATGATGAGATTATGAATGTGGAAATCCCGAACTTCCCACCACTTGTGT
TTGAATTTGATGACAAGCTAAACCTTACTGCTGAGTACTACCTCGGCGGTGAATAA

Upstream 100 bases:

>100_bases
ATAAAGAGAGGAATAGACTAGCTTTTTTGCCCTATTTTTTGTAAAATAGGAGTTGTAAAAAGGCAAGAAGCCTTTAAACT
TAATAAGGAGATATTAACTA

Downstream 100 bases:

>100_bases
TGCTGTGAGGCCAGACCTAGTTCTGGCTTTTTTTGTTATGTGATAAAAAAGGCGTTTCCAACAGAAATGTGATATGATAG
TTAAAAAGTGGTAAAAGAAG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVE
KSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDDKLNLTAEYYLGGE

Sequences:

>Translated_231_residues
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVE
KSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDDKLNLTAEYYLGGE
>Mature_231_residues
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVE
KSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDDKLNLTAEYYLGGE

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI50593010, Length=234, Percent_Identity=50.8547008547009, Blast_Score=246, Evalue=1e-65,
Organism=Homo sapiens, GI4505753, Length=232, Percent_Identity=50.4310344827586, Blast_Score=229, Evalue=1e-60,
Organism=Homo sapiens, GI4502445, Length=233, Percent_Identity=45.0643776824034, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI40353764, Length=233, Percent_Identity=45.0643776824034, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI71274132, Length=232, Percent_Identity=47.8448275862069, Blast_Score=216, Evalue=1e-56,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=54.6583850931677, Blast_Score=167, Evalue=1e-41,
Organism=Escherichia coli, GI1786970, Length=229, Percent_Identity=54.585152838428, Blast_Score=266, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6322697, Length=232, Percent_Identity=51.2931034482759, Blast_Score=251, Evalue=6e-68,
Organism=Saccharomyces cerevisiae, GI6320183, Length=286, Percent_Identity=29.7202797202797, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324516, Length=278, Percent_Identity=29.8561151079137, Blast_Score=122, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6324857, Length=108, Percent_Identity=34.2592592592593, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24646216, Length=231, Percent_Identity=51.5151515151515, Blast_Score=242, Evalue=1e-64,
Organism=Drosophila melanogaster, GI85725270, Length=233, Percent_Identity=48.068669527897, Blast_Score=219, Evalue=1e-57,
Organism=Drosophila melanogaster, GI85725272, Length=233, Percent_Identity=48.068669527897, Blast_Score=219, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24650981, Length=233, Percent_Identity=48.068669527897, Blast_Score=219, Evalue=1e-57,
Organism=Drosophila melanogaster, GI28571817, Length=220, Percent_Identity=38.1818181818182, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI28571815, Length=220, Percent_Identity=38.1818181818182, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24648979, Length=220, Percent_Identity=38.1818181818182, Blast_Score=165, Evalue=3e-41,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_STRE4 (C0M8R8)

Other databases:

- EMBL:   FM204883
- RefSeq:   YP_002746010.1
- ProteinModelPortal:   C0M8R8
- EnsemblBacteria:   EBSTRT00000066657
- GeneID:   7695645
- GenomeReviews:   FM204883_GR
- KEGG:   seu:SEQ_0656
- GeneTree:   EBGT00050000027479
- OMA:   TGWKDPD
- ProtClustDB:   PRK14117
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 26141; Mature: 26141

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 9-9 ACT_SITE 182-182

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIAFDLAFTSVLKR
CEEEEEEECCCCCCCCCEEEECEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVL
HHHHHCEEEEECCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCC
PPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERALPFWEDKIAPALVDGKNVFVG
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEHHHCCCCHHHCCCCEEECCCEEEEE
AHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDDKLNLTAEYYLGGE
ECCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCEEEEEEECCC
>Mature Secondary Structure
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIAFDLAFTSVLKR
CEEEEEEECCCCCCCCCEEEECEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVL
HHHHHCEEEEECCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCC
PPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERALPFWEDKIAPALVDGKNVFVG
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEHHHCCCCHHHCCCCEEECCCEEEEE
AHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDDKLNLTAEYYLGGE
ECCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA