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The map label for this gene is ftsA [H]

Identifier: 195977732

GI number: 195977732

Start: 620288

End: 621652

Strand: Direct

Name: ftsA [H]

Synonym: Sez_0594

Alternate gene names: 195977732

Gene position: 620288-621652 (Clockwise)

Preceding gene: 195977731

Following gene: 195977733

Centisome position: 30.64

GC content: 45.2

Gene sequence:

>1365_bases
ATGGCTAGAAATGGCTTTTTTACTGGTTTGGACATTGGAACAAGCTCGATAAAGGTTTTGGTAGCAGAGTTTATCTCTGG
CGAGATGAATGTTATTGGTGTGAGCAATGTTCCGAGTACTGGCGTAAAAGATGGCATAATCATTGATATAGAGGCAGCAG
CCGCTGCTATTAAAACTGCAGTAGAACAAGCTGAAGAAAAAGCAGGAATGACGATTGAAAGGGTCAATGTTGGGCTGCCA
GCAAACCTCCTTCAAATTGAGCCGACACAAGGCATGATTCCTGTTCCTAGCGAATCAAAAGAAATCAAAGATGAAGACGT
TGATAGCGTTGTTAAGTCAGCACTAACCAAGAGCATTACTCCAGAGCGAGAGGTGATTTCCTTAGTCCCTGAAGAGTTTA
TTGTAGACGGCTTTCAGGGCATTCGAGATCCTCGTGGCATGATGGGGATCAGGCTTGAAATGCGCGGTCTGATTTACACT
GGACCAAGCACAATCCTGCATAACTTAAGAAAGACAGTTGAGCGTGCTGGAATTAAGGTTGAAAACATCATCATTTCTCC
TTTGGCAATGGCTAAGGCGGTGTTAAATGAAGGTGAACGTGAATTTGGTGCTACGGTCATTGACATGGGTGGAGGACAAA
CCACCGTTGCCTCAATGCGAGCACAGGAATTGCAGTACACCAATATCTATGCAGAGGGCGGCGAGTATATCACAAAGGAT
ATCTCTAAGGTTCTTAAAACGTCAATGTCAATTGCAGAGGCCTTGAAGTACAATTTTGGGCAGGCTGATATGGCAGAGGC
GAGTCTGACTGATACCGTTAAGGTTGATGTTGTTGGCAGTGATGAGCCCGTTGAGGTAACAGAGCGTTACTTATCAGAGA
TTATCTCGGCTCGTGTTCGCCATATTCTAGATCGTGTTAAGCAGGATTTAGAAAGAGGACGCCTGCTTGATTTACCTGGT
GGCATTGTGCTGATAGGTGGCGGCGCCATTATGCCGGGCGTGGTTGAGGTTGCTCAAGAGATTTTTGGAACCAATGTTAA
GCTTCATATTCCAAATCAGGTTGGTATTCGTAACCCAATGTTTGCCAATGTCATTAGCTTGGTCGAGTACGTTGGTATGA
TGTCAGAGGTGGACGTTTTAGCGCAAAATGCTGTATCAGGCGAGGAATTGCTAAGACGTAAGCCGATCGACTTTACTGGC
CAAGAAGCTTACTTACCAGACTACAATGAAACTAGAGGGTTTGAGCCGGCTCCTAATTATGAGCAGCAAGTGCCCCAAGC
AGACTACGAGCCTCAAGAACCCGCTGAACCAAAGCAAAAGATTTCAGAGCGTGTTCGTGGCATTTTTGGAAGTATGTTTG
ATTAA

Upstream 100 bases:

>100_bases
CATTTTACGTTTTTTTATGATATAATATTCCCTGAATAATTCTGCTTTTTAGCAGTGTTTTTGAATAGTAAAAGTTTGGA
AAGTAAGTGAGGTCGAGTGA

Downstream 100 bases:

>100_bases
AAGTAATAAAGTGAGGAAATAAAATGGCATTTTCATTTGATACGGCATCCATTCAAGGTGCAATCATTAAGGTAATCGGT
GTTGGTGGAGGTGGCGGAAA

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKDGIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLP
ANLLQIEPTQGMIPVPSESKEIKDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
GPSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVASMRAQELQYTNIYAEGGEYITKD
ISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVDVVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPG
GIVLIGGGAIMPGVVEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLRRKPIDFTG
QEAYLPDYNETRGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFGSMFD

Sequences:

>Translated_454_residues
MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKDGIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLP
ANLLQIEPTQGMIPVPSESKEIKDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
GPSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVASMRAQELQYTNIYAEGGEYITKD
ISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVDVVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPG
GIVLIGGGAIMPGVVEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLRRKPIDFTG
QEAYLPDYNETRGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFGSMFD
>Mature_453_residues
ARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKDGIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLPA
NLLQIEPTQGMIPVPSESKEIKDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYTG
PSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVASMRAQELQYTNIYAEGGEYITKDI
SKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVDVVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPGG
IVLIGGGAIMPGVVEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLRRKPIDFTGQ
EAYLPDYNETRGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFGSMFD

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=379, Percent_Identity=31.6622691292876, Blast_Score=198, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494
- InterPro:   IPR021873 [H]

Pfam domain/function: PF11983 DUF3484; PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 49400; Mature: 49269

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKDGIIIDIEAAAAAIKTA
CCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEHHHHHHHHHH
VEQAEEKAGMTIERVNVGLPANLLQIEPTQGMIPVPSESKEIKDEDVDSVVKSALTKSIT
HHHHHHHHCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
PEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYTGPSTILHNLRKTVERAGIKV
CHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEECEEEEECHHHHHHHHHHHHHHHCCEE
ENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVASMRAQELQYTNIYAEGGEYITKD
EHHHHHHHHHHHHHHHCCCHHHCCEEEECCCCCHHHHHHHHHHHHHHEEEECCCHHHHHH
ISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVDVVGSDEPVEVTERYLSEIISARVR
HHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
HILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGVVEVAQEIFGTNVKLHIPNQVGIRNPM
HHHHHHHHHHHCCCEEECCCCEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCH
FANVISLVEYVGMMSEVDVLAQNAVSGEELLRRKPIDFTGQEAYLPDYNETRGFEPAPNY
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCH
EQQVPQADYEPQEPAEPKQKISERVRGIFGSMFD
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKDGIIIDIEAAAAAIKTA
CCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEHHHHHHHHHH
VEQAEEKAGMTIERVNVGLPANLLQIEPTQGMIPVPSESKEIKDEDVDSVVKSALTKSIT
HHHHHHHHCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
PEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYTGPSTILHNLRKTVERAGIKV
CHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEECEEEEECHHHHHHHHHHHHHHHCCEE
ENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVASMRAQELQYTNIYAEGGEYITKD
EHHHHHHHHHHHHHHHCCCHHHCCEEEECCCCCHHHHHHHHHHHHHHEEEECCCHHHHHH
ISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVDVVGSDEPVEVTERYLSEIISARVR
HHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
HILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGVVEVAQEIFGTNVKLHIPNQVGIRNPM
HHHHHHHHHHHCCCEEECCCCEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCH
FANVISLVEYVGMMSEVDVLAQNAVSGEELLRRKPIDFTGQEAYLPDYNETRGFEPAPNY
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCH
EQQVPQADYEPQEPAEPKQKISERVRGIFGSMFD
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10520745 [H]