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The map label for this gene is desR [H]

Identifier: 195977721

GI number: 195977721

Start: 609747

End: 610343

Strand: Direct

Name: desR [H]

Synonym: Sez_0583

Alternate gene names: 195977721

Gene position: 609747-610343 (Clockwise)

Preceding gene: 195977720

Following gene: 195977723

Centisome position: 30.12

GC content: 38.53

Gene sequence:

>597_bases
ATGAAACTATTGATTGCTGAGGATCAAGCAATGTTAAGAGATGCCTTAAAGCAGCTACTGTTAATGGAGGAGGGGGTTCA
AACCGTTGCAGCTGTTGCAACTGGTCAGGAGGCTGTAGCTTTTTTGAGTCAGCATCAGGTTGATGTTGCTATTTTAGATG
TGGAAATGCCAGAGAAAAATGGGTTAGATGTCTTAGAATGGATTAAAGCAACCAGTGATACAAAGGTTATCATTGTAACC
ACCTTTAAGCGCCTAGGCTATTTTCAAAGGGCTGTCAAGGCAGGAGCTGACGCTTATGTTCTAAAGGATAGATCAATCTC
AGAGCTGATGACAACAATCAAAACAGTCTTGTCCGGTGGCAAGGAGTATTCGCCAGAGCTTATGGAAAATATAGTTGTCA
ATCCTAACCCATTAAGCAAGCAGGAAATGAATATTCTCTATTTAATTGCTCAAGGCAAAACAAGTAAAGAAATAAGCCAG
ATATTGTTTTTATCTAATGGAACCATCAGAAATTATATTTCGTCTATTTTTAATAAATTCGGAGTTTCTAATAGAATGGA
GGCTATCAGTCTGGCTAAAGAAAATGGTTGGCTATAG

Upstream 100 bases:

>100_bases
TCTATAAAAGAGCGATTGTTATTGGTAGATGGAGACGTTAGGATCGAATCTCCCCAAGCTCCGACCAGAATAGTGGTTTA
TTTAAATGAGGGTGTGAGTG

Downstream 100 bases:

>100_bases
GTGGTAGCTCACTAATAACCCTAAGCCCTAGCTGCTTGATGTAGCTAGGGCTTTTGTGATCTAATGGCCAGTGAGCCTTT
CAAATAGCAATATGGCCATA

Product: TCS response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MKLLIAEDQAMLRDALKQLLLMEEGVQTVAAVATGQEAVAFLSQHQVDVAILDVEMPEKNGLDVLEWIKATSDTKVIIVT
TFKRLGYFQRAVKAGADAYVLKDRSISELMTTIKTVLSGGKEYSPELMENIVVNPNPLSKQEMNILYLIAQGKTSKEISQ
ILFLSNGTIRNYISSIFNKFGVSNRMEAISLAKENGWL

Sequences:

>Translated_198_residues
MKLLIAEDQAMLRDALKQLLLMEEGVQTVAAVATGQEAVAFLSQHQVDVAILDVEMPEKNGLDVLEWIKATSDTKVIIVT
TFKRLGYFQRAVKAGADAYVLKDRSISELMTTIKTVLSGGKEYSPELMENIVVNPNPLSKQEMNILYLIAQGKTSKEISQ
ILFLSNGTIRNYISSIFNKFGVSNRMEAISLAKENGWL
>Mature_198_residues
MKLLIAEDQAMLRDALKQLLLMEEGVQTVAAVATGQEAVAFLSQHQVDVAILDVEMPEKNGLDVLEWIKATSDTKVIIVT
TFKRLGYFQRAVKAGADAYVLKDRSISELMTTIKTVLSGGKEYSPELMENIVVNPNPLSKQEMNILYLIAQGKTSKEISQ
ILFLSNGTIRNYISSIFNKFGVSNRMEAISLAKENGWL

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=194, Percent_Identity=31.9587628865979, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1788222, Length=207, Percent_Identity=26.5700483091787, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788521, Length=197, Percent_Identity=28.4263959390863, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1786747, Length=200, Percent_Identity=27.5, Blast_Score=80, Evalue=6e-17,
Organism=Escherichia coli, GI1788712, Length=203, Percent_Identity=25.615763546798, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787473, Length=198, Percent_Identity=26.7676767676768, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 21971; Mature: 21971

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLIAEDQAMLRDALKQLLLMEEGVQTVAAVATGQEAVAFLSQHQVDVAILDVEMPEKN
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCCC
GLDVLEWIKATSDTKVIIVTTFKRLGYFQRAVKAGADAYVLKDRSISELMTTIKTVLSGG
CCHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCC
KEYSPELMENIVVNPNPLSKQEMNILYLIAQGKTSKEISQILFLSNGTIRNYISSIFNKF
CCCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
GVSNRMEAISLAKENGWL
CCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLLIAEDQAMLRDALKQLLLMEEGVQTVAAVATGQEAVAFLSQHQVDVAILDVEMPEKN
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCCC
GLDVLEWIKATSDTKVIIVTTFKRLGYFQRAVKAGADAYVLKDRSISELMTTIKTVLSGG
CCHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCC
KEYSPELMENIVVNPNPLSKQEMNILYLIAQGKTSKEISQILFLSNGTIRNYISSIFNKF
CCCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
GVSNRMEAISLAKENGWL
CCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]