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The map label for this gene is lacT [H]

Identifier: 195977599

GI number: 195977599

Start: 480030

End: 480881

Strand: Direct

Name: lacT [H]

Synonym: Sez_0458

Alternate gene names: 195977599

Gene position: 480030-480881 (Clockwise)

Preceding gene: 195977598

Following gene: 195977600

Centisome position: 23.71

GC content: 41.31

Gene sequence:

>852_bases
ATGTTAAAAAAGGAGGTAAGAATGTTCCGACTGATTCGTCCATTGAATAACAATGCCGCCTTGGTTAAGAATGCTGCCAA
CGAGCAGGCAGTAGTTATGGGGGCAGGAATTGCTTTTCAGAAGAAAAAAGGAGACTTGATTCGAGAAGAAGCCGTTGAAA
AAACATTTTTATTAAAAAATGATGAAGCAAGGGAAAACTTACTGCTCTTGCTAAAAGATGTGCCGTTAGATGTCATTACG
GTGACCTATGATGTGATTGATTGGCTGGTCTTGACCTATCATTACCCGGTCCAGCAGTACCTTTATGTGACATTGACCGA
TCATATCTATGCTGCTTATCACATGCTGCAAAAGGGGACCTATTCGGTTAATCGCTTGCCTGACATTTCTAAAGAATTTG
GTCAGGAATATGAGATGGCACAGGCTGCTCTGGAGATGTTTCGGCAAAGGCTAAGGACAACCTTTCCAGATGATGAGGTG
ACAAAGATTGCCCTGCATTTTATTAATGCTAAGGGTGAAGAATCTAGTCCTCAACGAGAGCATAGCAGCACCAAAAAGCT
GCTTAATCAGGTGGAAGCAGCCTTGATGGCTAATGGGATTACACGAACAAGCACTAACAGTCATTTTTATGATCGACTGA
TGATCCATTTGACCTATTTTATCCAGTCGCTAGACCGTAAGAATCAAGGCTATCATGCTATGGGGAGCTTGGAACAGCAG
ATCAAAAAGGAATACCCAAAAGCCTATGAGATAGGCAATGCTATCTATCAGCTGATGACAGATTTAACAGGTCAAGAGTT
GGTAGAGTCTGAAAAAATCTACATTGTAATCCATATTCAACGCTTACTATAA

Upstream 100 bases:

>100_bases
TTACAATGACAAACGTATATGGTGGATTGTGACTAAAGCTGATTTAGGCAAGACCGCAAACGAATTGGGAGCTTTTTTCT
GATTGGTTTGTGGTCTTTTT

Downstream 100 bases:

>100_bases
AGGAGACAAAATGACTAAAGACGAAATAACCATGCTTGGCTTTGAAATTGTTGCTTATGCTGGTGAAGCCAGATCGAAGC
TGATTGAGGCCTTAGAGGCC

Product: transcription antiterminator LacT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MLKKEVRMFRLIRPLNNNAALVKNAANEQAVVMGAGIAFQKKKGDLIREEAVEKTFLLKNDEARENLLLLLKDVPLDVIT
VTYDVIDWLVLTYHYPVQQYLYVTLTDHIYAAYHMLQKGTYSVNRLPDISKEFGQEYEMAQAALEMFRQRLRTTFPDDEV
TKIALHFINAKGEESSPQREHSSTKKLLNQVEAALMANGITRTSTNSHFYDRLMIHLTYFIQSLDRKNQGYHAMGSLEQQ
IKKEYPKAYEIGNAIYQLMTDLTGQELVESEKIYIVIHIQRLL

Sequences:

>Translated_283_residues
MLKKEVRMFRLIRPLNNNAALVKNAANEQAVVMGAGIAFQKKKGDLIREEAVEKTFLLKNDEARENLLLLLKDVPLDVIT
VTYDVIDWLVLTYHYPVQQYLYVTLTDHIYAAYHMLQKGTYSVNRLPDISKEFGQEYEMAQAALEMFRQRLRTTFPDDEV
TKIALHFINAKGEESSPQREHSSTKKLLNQVEAALMANGITRTSTNSHFYDRLMIHLTYFIQSLDRKNQGYHAMGSLEQQ
IKKEYPKAYEIGNAIYQLMTDLTGQELVESEKIYIVIHIQRLL
>Mature_283_residues
MLKKEVRMFRLIRPLNNNAALVKNAANEQAVVMGAGIAFQKKKGDLIREEAVEKTFLLKNDEARENLLLLLKDVPLDVIT
VTYDVIDWLVLTYHYPVQQYLYVTLTDHIYAAYHMLQKGTYSVNRLPDISKEFGQEYEMAQAALEMFRQRLRTTFPDDEV
TKIALHFINAKGEESSPQREHSSTKKLLNQVEAALMANGITRTSTNSHFYDRLMIHLTYFIQSLDRKNQGYHAMGSLEQQ
IKKEYPKAYEIGNAIYQLMTDLTGQELVESEKIYIVIHIQRLL

Specific function: Mediates positive regulation of the lac operon by functioning as an antiterminator factor of transcription [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PRD domains [H]

Homologues:

Organism=Escherichia coli, GI1790160, Length=275, Percent_Identity=27.2727272727273, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004341
- InterPro:   IPR011608
- InterPro:   IPR001550 [H]

Pfam domain/function: PF03123 CAT_RBD; PF00874 PRD [H]

EC number: NA

Molecular weight: Translated: 32779; Mature: 32779

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKEVRMFRLIRPLNNNAALVKNAANEQAVVMGAGIAFQKKKGDLIREEAVEKTFLLKN
CCHHHHHHHHHHHCCCCCHHEEECCCCCCEEEEECCEEEECCCCCHHHHHHHHHHHHCCC
DEARENLLLLLKDVPLDVITVTYDVIDWLVLTYHYPVQQYLYVTLTDHIYAAYHMLQKGT
CCHHHHHEEHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHHHHHHHHHHHHCCC
YSVNRLPDISKEFGQEYEMAQAALEMFRQRLRTTFPDDEVTKIALHFINAKGEESSPQRE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHH
HSSTKKLLNQVEAALMANGITRTSTNSHFYDRLMIHLTYFIQSLDRKNQGYHAMGSLEQQ
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
IKKEYPKAYEIGNAIYQLMTDLTGQELVESEKIYIVIHIQRLL
HHHHCCHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEEEEECC
>Mature Secondary Structure
MLKKEVRMFRLIRPLNNNAALVKNAANEQAVVMGAGIAFQKKKGDLIREEAVEKTFLLKN
CCHHHHHHHHHHHCCCCCHHEEECCCCCCEEEEECCEEEECCCCCHHHHHHHHHHHHCCC
DEARENLLLLLKDVPLDVITVTYDVIDWLVLTYHYPVQQYLYVTLTDHIYAAYHMLQKGT
CCHHHHHEEHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHHHHHHHHHHHHCCC
YSVNRLPDISKEFGQEYEMAQAALEMFRQRLRTTFPDDEVTKIALHFINAKGEESSPQRE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHH
HSSTKKLLNQVEAALMANGITRTSTNSHFYDRLMIHLTYFIQSLDRKNQGYHAMGSLEQQ
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
IKKEYPKAYEIGNAIYQLMTDLTGQELVESEKIYIVIHIQRLL
HHHHCCHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9045813; 9066115; 2125053 [H]