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The map label for this gene is accA [H]

Identifier: 195977558

GI number: 195977558

Start: 443528

End: 444298

Strand: Direct

Name: accA [H]

Synonym: Sez_0417

Alternate gene names: 195977558

Gene position: 443528-444298 (Clockwise)

Preceding gene: 195977557

Following gene: 195977560

Centisome position: 21.91

GC content: 45.78

Gene sequence:

>771_bases
ATGACAGACGTCGCAAGAATATTAAAGGAAGCGCGTGACCAGGGTCGAATGACAGCTCTAGATTATGCCAGCCTGATTTT
TGATGAGTTTATGGAGTTGCATGGGGATCGTCAGTTTGCTGATGATGGCTCTATTGTTGGTGGGATTGCCTATTTGGCTG
ATCAGCCAGTCACAGTGATTGGTATTCAAAAAGGAAAAAATCTTCAAGATAATCTGGCTAGAAATTTTGGGCAACCGCAT
CCTGAGGGCTACCGTAAGGCTTTACGCTTAATGAAGCAGGCTGAAAAATTTGGCCGTCCGGTGATTACCTTTATCAATAC
AGCAGGGGCTTATCCGGGCGTCGGTGCTGAGGAGCGCGGTCAAGGTGAAGCTATTGCCAGAAACTTGATGGAAATGAGTG
ACCTCAAGGTTCCTATCATTGCTATTATTATTGGCGAGGGCGGATCAGGCGGTGCTTTAGCCTTAGCTGTTGCTGATCAG
GTTTGGATGCTGGAAAACACCATGTACGCTGTTCTTAGTCCAGAAGGCTTTGCCTCTATCCTCTGGAAGGATGGCTCTAG
GGCTACTGAAGCTGCTGAGCTCATGAAAATTACCGCAGCTGAGCTGTATCAAATGGGTGTCATTGATCGGATTATTCCAG
AGCGGGGTTATTTTTCGAGTGAGATTATTGAGATGATAAGATCACACTTAATTGACGAAATCACTCAGCTGCAGGCTAAG
TCCTTGGAGGAATTACTGGATCAGCGTTACCAGCGCTTTAGAAAATATTAA

Upstream 100 bases:

>100_bases
CAGAGTTCTTAAAAGAGCATGGCTTTGTTGACGCTATTGTGAAGCGGACTGACCTGCGTGATCGGATTGCTCATTTGGTG
GCATTTCATGGAGGTGTATC

Downstream 100 bases:

>100_bases
GGACATCAAAAAGACCTCTGTAAGGCTAGCAGTTAGCTAGGCGTTACAGAGGTCTTCTTTATTGTTAGGATCAATCTCAT
TAATCGGCTCTTTGTCCCCC

Product: acetyl-CoA carboxylase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGSIVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPH
PEGYRKALRLMKQAEKFGRPVITFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYFSSEIIEMIRSHLIDEITQLQAK
SLEELLDQRYQRFRKY

Sequences:

>Translated_256_residues
MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGSIVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPH
PEGYRKALRLMKQAEKFGRPVITFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYFSSEIIEMIRSHLIDEITQLQAK
SLEELLDQRYQRFRKY
>Mature_255_residues
TDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGSIVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPHP
EGYRKALRLMKQAEKFGRPVITFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQV
WMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYFSSEIIEMIRSHLIDEITQLQAKS
LEELLDQRYQRFRKY

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=255, Percent_Identity=54.1176470588235, Blast_Score=265, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 28433; Mature: 28302

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGSIVGGIAYLADQPVTVI
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEE
GIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVITFINTAGAYPGVGAEERG
EECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCCCCCCCCC
QGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQVWMLENTMYAVLSPEGFASI
CHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEHHHHHHHHHHHHCEEEEECCCCHHHH
LWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYFSSEIIEMIRSHLIDEITQLQAK
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SLEELLDQRYQRFRKY
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGSIVGGIAYLADQPVTVI
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEE
GIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVITFINTAGAYPGVGAEERG
EECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCCCCCCCCC
QGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQVWMLENTMYAVLSPEGFASI
CHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEHHHHHHHHHHHHCEEEEECCCCHHHH
LWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYFSSEIIEMIRSHLIDEITQLQAK
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SLEELLDQRYQRFRKY
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA