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The map label for this gene is fabZ [H]

Identifier: 195977556

GI number: 195977556

Start: 440836

End: 441258

Strand: Direct

Name: fabZ [H]

Synonym: Sez_0413

Alternate gene names: 195977556

Gene position: 440836-441258 (Clockwise)

Preceding gene: 195977555

Following gene: 195977557

Centisome position: 21.78

GC content: 43.74

Gene sequence:

>423_bases
ATGATGGATATAAAACAGATTCAAGAAGCACTGCCACATCGTTACCCAATGCTGCTTGTTGATAGGATTTTAGAGGCTTC
AGACGATGAAATTGTTGCCATCAAAAATGTCACTATCAATGAGCCCTTCTTTAACGGTCATTTTCCTCAGTATCCAGTCA
TGCCAGGTGTTTTGATCATGGAGGCCTTGGCACAAACTGCTGGCGTCTTGGAGCTATCAAAAGAGGAAAATAAAGGCAAG
CTTGTTTTTTACGCTGGTATGGACAAGGTAAAATTTAAAAAGCAGGTGGTTCCGGGAGACCAGCTAGTCATGACAGCTAG
GTTTATTAAGCGTCGTGGGACAATAGCAGTTGTTGAGGCCAAGGCAGAGGTTGATGGCAAATTAGCAGCTAGTGGGACCT
TGACCTTTGCTTTTGGGCAGTAA

Upstream 100 bases:

>100_bases
TCATGAACGAGATTCCTGCTCCTTGCGACGGTATCGTGACAGAGATTTTAGTGGCCAATGAGGACGTGGTTGAGTTTGGA
CAAGGATTGGTACGCATTAA

Downstream 100 bases:

>100_bases
AAGACTAATCGTCTGTGGAGGAAAAAAGAAACCTATGTTTAACAAAATCTTAATTGCCAATCGTGGTGAAATAGCAGTGC
GGATTATTCGTGCAGCACGA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: 2-decenoyl-[acyl-carrier protein]; 3-decenoyl-[acyl-carrier protein]; H2O

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFFNGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGK
LVFYAGMDKVKFKKQVVPGDQLVMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ

Sequences:

>Translated_140_residues
MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFFNGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGK
LVFYAGMDKVKFKKQVVPGDQLVMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ
>Mature_140_residues
MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFFNGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGK
LVFYAGMDKVKFKKQVVPGDQLVMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=139, Percent_Identity=45.3237410071942, Blast_Score=131, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.60

Molecular weight: Translated: 15524; Mature: 15524

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFFNGHFPQYPVMPGVLIM
CCCHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECEEECCCCCCCCCCCCCCCCHHHHH
EALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQLVMTARFIKRRGTIAVVEA
HHHHHHCCCEEECCCCCCCCEEEEECCCCHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEE
KAEVDGKLAASGTLTFAFGQ
CCCCCCEEECCCEEEEEECC
>Mature Secondary Structure
MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFFNGHFPQYPVMPGVLIM
CCCHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECEEECCCCCCCCCCCCCCCCHHHHH
EALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQLVMTARFIKRRGTIAVVEA
HHHHHHCCCEEECCCCCCCCEEEEECCCCHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEE
KAEVDGKLAASGTLTFAFGQ
CCCCCCEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxydecanoyl-[acyl-carrier protein]

Specific reaction: (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2-decenoyl-[acyl- $carrier protein] (or 3-decenoyl-[acyl-carrier protein]) + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA