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The map label for this gene is vanYB [H]

Identifier: 195977541

GI number: 195977541

Start: 426422

End: 427165

Strand: Direct

Name: vanYB [H]

Synonym: Sez_0398

Alternate gene names: 195977541

Gene position: 426422-427165 (Clockwise)

Preceding gene: 195977540

Following gene: 195977542

Centisome position: 21.07

GC content: 45.43

Gene sequence:

>744_bases
ATGAAGAATAACGCTATAAGAGTCCTTTTGCAGGCCTTGGTCGTCCTTTTGTTTTTATCAGGGATTTATCTTTTTATCAA
GCCTGAACAACAGGCTGTAGGACAAAAGGCAAACCAAACAGCACCTGCTCCAAAGGCAGTTAAGCAGGCTAAAAAAACTA
CTGATCTGCCAAAGGTATCAGCTACGGACTGGCAGCTGGTCCTCGTCAATCACGATCACCCTCAAGAGGAAAGAAGCCCT
GAGTTGGTTGAGATTAATGGGATTCCTATTGATAAGCGCATTGAGCAGGAGACGGCTGATTTTCTAGCAGCGGCGCAGAC
GATTGAACCTCAGGAGCACTTGATTGCTGGTTATCGTTCGGTTGTCCAGCAAGAAGAGCTTTATCAGTCTTATATTGCCC
AAGAGCTGGCAAATGATCCTAGCCTGACCCAAGAGGCAGCTGAAGCCTTGGTTCGGAAATATGCCCAGCCAGCAGGCACT
AGTGAACATCAGACTGGTCTAGCCATTGATATGAGCACAGTAGATAACTTAAACGCTAGTGATCCTAAGGTGGCACAGGA
GATTCAAAAAATAGCTCCACAATTTGGTTTTATTTTGCGCTATCCAAAAGGGAAGCAGACTAGCACAGGGATTGAGTATG
AGGACTGGCATTATCGCTATGTTGGTAAAGCCTCTGCCCAATACATTACCGCTCATAGCCTCAGCCTAGAAGAATACCTA
ACACGATTGAAGGAGAAAAAATGA

Upstream 100 bases:

>100_bases
GTCACTGTTGTGGAATTTGAAAATGGGCAGTTTACCATCAAGACGATTGGAGATATGAGCTACCGCTATTGTGGTCGTGA
GATAATTGAGTCAATAAGAG

Downstream 100 bases:

>100_bases
GAAAACGACTTAAATTTTCCTATTTTCTAGTGTTTTTAGTGTTCATTATGGTGGCTTTGATTGGTCCCTTGCTGTTCAAT
GCCAAAGGCACATCGGCCAG

Product: D-alanyl-D-alanine carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MKNNAIRVLLQALVVLLFLSGIYLFIKPEQQAVGQKANQTAPAPKAVKQAKKTTDLPKVSATDWQLVLVNHDHPQEERSP
ELVEINGIPIDKRIEQETADFLAAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHYRYVGKASAQYITAHSLSLEEYL
TRLKEKK

Sequences:

>Translated_247_residues
MKNNAIRVLLQALVVLLFLSGIYLFIKPEQQAVGQKANQTAPAPKAVKQAKKTTDLPKVSATDWQLVLVNHDHPQEERSP
ELVEINGIPIDKRIEQETADFLAAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHYRYVGKASAQYITAHSLSLEEYL
TRLKEKK
>Mature_247_residues
MKNNAIRVLLQALVVLLFLSGIYLFIKPEQQAVGQKANQTAPAPKAVKQAKKTTDLPKVSATDWQLVLVNHDHPQEERSP
ELVEINGIPIDKRIEQETADFLAAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHYRYVGKASAQYITAHSLSLEEYL
TRLKEKK

Specific function: Vancomycin-inducible, penicillin-resistant, DD- carboxypeptidase that hydrolyzes depsipeptide- and D-alanyl-D- alanine-containing peptidoglycan precursors. Insensitive to beta- lactams [H]

COG id: COG1876

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M15B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009045
- InterPro:   IPR003709 [H]

Pfam domain/function: PF02557 VanY [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 27670; Mature: 27670

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNAIRVLLQALVVLLFLSGIYLFIKPEQQAVGQKANQTAPAPKAVKQAKKTTDLPKVS
CCCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCC
ATDWQLVLVNHDHPQEERSPELVEINGIPIDKRIEQETADFLAAAQTIEPQEHLIAGYRS
CCCEEEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGTSEHQTGLAIDMSTVDNLNAS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHCCCCCC
DPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHYRYVGKASAQYITAHSLSLEEYL
CCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCHHHHH
TRLKEKK
HHHHCCC
>Mature Secondary Structure
MKNNAIRVLLQALVVLLFLSGIYLFIKPEQQAVGQKANQTAPAPKAVKQAKKTTDLPKVS
CCCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCC
ATDWQLVLVNHDHPQEERSPELVEINGIPIDKRIEQETADFLAAAQTIEPQEHLIAGYRS
CCCEEEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGTSEHQTGLAIDMSTVDNLNAS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHCCCCCC
DPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHYRYVGKASAQYITAHSLSLEEYL
CCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCHHHHH
TRLKEKK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8631706; 12663927 [H]