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The map label for this gene is alr [H]

Identifier: 195977514

GI number: 195977514

Start: 391419

End: 392519

Strand: Direct

Name: alr [H]

Synonym: Sez_0369

Alternate gene names: 195977514

Gene position: 391419-392519 (Clockwise)

Preceding gene: 195977513

Following gene: 195977515

Centisome position: 19.34

GC content: 45.69

Gene sequence:

>1101_bases
ATGATTTCAAGCTTACATCGACCAACAGTAGCTAGAGTTGACTTAGAGGCTATTCAGGCAAATATTGATAAGATTCAAAG
GCATATCCCTAAAAAGGTAAAGACATACGCTGTCGTCAAGGCCAATGCTTATGGTCATGGGGCAGTTGCAGTGTCCAAGG
CAGTTGAGGATCAGGTTGATGGCTATTGCGTATCAAACCTTGATGAAGCCTTGGAATTACGTCAGGCAGGCATTGATAAG
GAAATCCTTATTTTAGGGGTGATTTTAGCAAGTGAATTGCAGCTAGCCATTAAGCATCAGCTGACGATAACGGTGGCCAG
CTTAGAGTGGCTAGAGCTTGCCAAAAAGGAATCGGTTGATTTCAGTCAGCTTCATGTGCATGTCAAGGTTGACTCGGGAA
TGGGGCGCATTGGTGTCAGGTCGCTTGCTGAGGCCAATCAGCTCATCTCAATCTTATCCGATATGGGAGTGCAGCTTGAC
GGGATTTTCACGCATTTTGCAACCGCAGATGAGTCTGACCATGCCATGTTCGATAAGCAGCTGACCTTTTTCAAGCAGTT
GGTGGAGCAGCTAGATAAGAGGCCTGCATTAGTGCATGCAAGCAACTCTGCAACAAGCCTTTGGCATAGTGAAACAATTT
TTAATGCCATTCGTCTTGGGATTGTTATCTATGGACTCAATCCCAGCGGCAATAGCTTGAGTCTACCTTGTCCCTTAAAG
GAAGCCTTGTCCTTAGAGTCGCGTTTGGTTCATGTGAAGCAAATTCAAGCAGGGGATAGCGTTGGCTATGGGGCTAGCTA
TGTAGCAGCAGAGTCAGAGTATGTCGGAACCTTACCTATTGGTTATGCTGACGGTTGGACTCGGAATATGCAGGGCTTTA
AGGTATTGGTAGAAGGGGAATTTTGTGACATTATTGGTCGTGTGTCGATGGATCAATTGACCATTCGTTTGCTTCAAGCC
TATCCTATCGGCACCAAGGTGACCTTGATTGGGCAGCAGGGTAAACAAGTGATCACAGCCACCGATGTTGCCGATTATAG
AGGTACGATTAATTATGAGGTGCTTTGCTTGCTGAGTGATCGTATTCCTAGAGAATATTAG

Upstream 100 bases:

>100_bases
GTCCCGTCATTACAAAATCTCCCTTTCAGGGGAAGGCCTTTATCAGTATTTCACATAGTGGGGGCTATGTTCAAGCAAGT
GTTATTTTGGAGGATTTAGC

Downstream 100 bases:

>100_bases
GAAATTGAGCCTAGGCTCAACTATTGACTGGCCTCAAGGCTGTTTTTCAAATGATTAGTCCTGTAAAGGTCTTGAGATCT
CAGGCTAATAGCGTGAATAA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MISSLHRPTVARVDLEAIQANIDKIQRHIPKKVKTYAVVKANAYGHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDK
EILILGVILASELQLAIKHQLTITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
GIFTHFATADESDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIRLGIVIYGLNPSGNSLSLPCPLK
EALSLESRLVHVKQIQAGDSVGYGASYVAAESEYVGTLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLLQA
YPIGTKVTLIGQQGKQVITATDVADYRGTINYEVLCLLSDRIPREY

Sequences:

>Translated_366_residues
MISSLHRPTVARVDLEAIQANIDKIQRHIPKKVKTYAVVKANAYGHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDK
EILILGVILASELQLAIKHQLTITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
GIFTHFATADESDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIRLGIVIYGLNPSGNSLSLPCPLK
EALSLESRLVHVKQIQAGDSVGYGASYVAAESEYVGTLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLLQA
YPIGTKVTLIGQQGKQVITATDVADYRGTINYEVLCLLSDRIPREY
>Mature_366_residues
MISSLHRPTVARVDLEAIQANIDKIQRHIPKKVKTYAVVKANAYGHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDK
EILILGVILASELQLAIKHQLTITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
GIFTHFATADESDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIRLGIVIYGLNPSGNSLSLPCPLK
EALSLESRLVHVKQIQAGDSVGYGASYVAAESEYVGTLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLLQA
YPIGTKVTLIGQQGKQVITATDVADYRGTINYEVLCLLSDRIPREY

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=367, Percent_Identity=35.6948228882834, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1790487, Length=361, Percent_Identity=31.5789473684211, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 40144; Mature: 40144

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSLHRPTVARVDLEAIQANIDKIQRHIPKKVKTYAVVKANAYGHGAVAVSKAVEDQVD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHEEEEEEECCCCCCHHHHHHHHHHHCC
GYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLTITVASLEWLELAKKESVD
CEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEEEEEEEHHHHHHHHHHCCCC
FSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLDGIFTHFATADESDHAMFDKQ
HHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHEEEEECCCCCCHHHHHHH
LTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIRLGIVIYGLNPSGNSLSLPCPLK
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHEEEEEEEEECCCCCEEECCCCHH
EALSLESRLVHVKQIQAGDSVGYGASYVAAESEYVGTLPIGYADGWTRNMQGFKVLVEGE
HHHCHHHHHEEEEEECCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCEEEEEECC
FCDIIGRVSMDQLTIRLLQAYPIGTKVTLIGQQGKQVITATDVADYRGTINYEVLCLLSD
HHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECHHHHCCCCCEEEEEEEEC
RIPREY
CCCCCC
>Mature Secondary Structure
MISSLHRPTVARVDLEAIQANIDKIQRHIPKKVKTYAVVKANAYGHGAVAVSKAVEDQVD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHEEEEEEECCCCCCHHHHHHHHHHHCC
GYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLTITVASLEWLELAKKESVD
CEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEEEEEEEHHHHHHHHHHCCCC
FSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLDGIFTHFATADESDHAMFDKQ
HHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHEEEEECCCCCCHHHHHHH
LTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIRLGIVIYGLNPSGNSLSLPCPLK
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHEEEEEEEEECCCCCEEECCCCHH
EALSLESRLVHVKQIQAGDSVGYGASYVAAESEYVGTLPIGYADGWTRNMQGFKVLVEGE
HHHCHHHHHEEEEEECCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCEEEEEECC
FCDIIGRVSMDQLTIRLLQAYPIGTKVTLIGQQGKQVITATDVADYRGTINYEVLCLLSD
HHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECHHHHCCCCCEEEEEEEEC
RIPREY
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA