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The map label for this gene is polC [H]

Identifier: 195977438

GI number: 195977438

Start: 313233

End: 313820

Strand: Direct

Name: polC [H]

Synonym: Sez_0293

Alternate gene names: 195977438

Gene position: 313233-313820 (Clockwise)

Preceding gene: 195977437

Following gene: 195977439

Centisome position: 15.47

GC content: 42.01

Gene sequence:

>588_bases
ATGAAACAATTAGAAGCATATATTGCCTTTGATATGGAATTTAATACTGTCAATGAGGTTAGTCATATCATTCAGCTTTC
AGCGGTCAAATGGCACAAGCATCAGGAGGTTGACAGCTTTGACAGCTATGTTTACACTGCTGTTCCCCTGCAAAGCTTTA
TCAATGGCCTGACAGGCATTACCTCAGATAAGATCGTATCAGCACCCAAGGTTGATGAGGTGCTTGCTGCCTTTAAGCAA
TTTGTTGGCGATATGCCTTTGATAGGCTACAATGCTCAAAAATCTGATTTGCCTATCTTAGCAGCAAATGGCTTGGATCT
GTCAGCGCAATATGCAGTCGATGTCTTTGACGAAGCCTATGAGAGACGAAGCAGTGACTTAAATGGAATTGCTAATCTTC
GCCTGCAAACAGTTGCTGATTTTTTAGGGATAAAAGGAAGAGGACATAATAGCTTAGAGGACGCTCGTATGACAGCGCGT
GTCTATGAAGCGTTTGTGGAATTTGACGACAATAAGTCTTACCTAAACAAACAAAAAGAAGCGATTACAGATAACCCCTT
TGCAGCTCTGGGAGGGCTTTTTGACTAG

Upstream 100 bases:

>100_bases
TACAGTCTGAAATGGGACCTAAAAAAGGTTTTTTAAATCGTTTATTTGGTAAATAACAGCATACCAAGACCCTCTAAGGG
TCTTTTTTGAGGAGAGAAGA

Downstream 100 bases:

>100_bases
CAGCGCTAGTCATTTCTCTGAAAAAGAAAAATGACCTAAGGTCAGGGCTTGCTTGTGACCTTGGGTCATATTCTATAATG
AGGACAGAAAGGAGGTGAAA

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYVYTAVPLQSFINGLTGITSDKIVSAPKVDEVLAAFKQ
FVGDMPLIGYNAQKSDLPILAANGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
VYEAFVEFDDNKSYLNKQKEAITDNPFAALGGLFD

Sequences:

>Translated_195_residues
MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYVYTAVPLQSFINGLTGITSDKIVSAPKVDEVLAAFKQ
FVGDMPLIGYNAQKSDLPILAANGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
VYEAFVEFDDNKSYLNKQKEAITDNPFAALGGLFD
>Mature_195_residues
MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYVYTAVPLQSFINGLTGITSDKIVSAPKVDEVLAAFKQ
FVGDMPLIGYNAQKSDLPILAANGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
VYEAFVEFDDNKSYLNKQKEAITDNPFAALGGLFD

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR023223
- InterPro:   IPR016027
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 21696; Mature: 21696

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYVYTAVPLQSFINGLTGI
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
TSDKIVSAPKVDEVLAAFKQFVGDMPLIGYNAQKSDLPILAANGLDLSAQYAVDVFDEAY
CCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
ERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTARVYEAFVEFDDNKSYLNKQKE
HHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AITDNPFAALGGLFD
HHCCCCHHHHCCCCC
>Mature Secondary Structure
MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYVYTAVPLQSFINGLTGI
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
TSDKIVSAPKVDEVLAAFKQFVGDMPLIGYNAQKSDLPILAANGLDLSAQYAVDVFDEAY
CCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
ERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTARVYEAFVEFDDNKSYLNKQKE
HHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AITDNPFAALGGLFD
HHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]