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The map label for this gene is gcp [H]

Identifier: 195977433

GI number: 195977433

Start: 308433

End: 309449

Strand: Direct

Name: gcp [H]

Synonym: Sez_0288

Alternate gene names: 195977433

Gene position: 308433-309449 (Clockwise)

Preceding gene: 195977432

Following gene: 195977434

Centisome position: 15.24

GC content: 47.89

Gene sequence:

>1017_bases
ATGACAGATAGATATATTTTAGCGGTAGAGAGCTCTTGTGATGAGACAAGTGTTGCTGTCTTAAAAAACGATAACGTCTT
ATTGACCAATATTATTGCTAGTCAGGTTGAAAGTCACAAGCGTTTTGGTGGGGTGGTTCCTGAGGTAGCAAGTCGTCATC
ATGTGGAGGTGATTACGACTTGCTTTGATGACGCACTGAAGGAGGCCCAGCTTGAGGCTTCTGACTTGACTGCGGTTGCG
GTTACCTATGGCCCAGGTCTGGTGGGGGCCTTGCTAGTCGGCCTAGCAGCAGCCAAGGCCTTTGCTTGGGCTAATGATTT
GCCCTTGATTCCAGTCAATCATATGGCAGGGCACCTGATGGCGGCACGCGAGCAAGGAGAGCTGGAATACCCTCTTATGG
CTCTCTTGGTTTCTGGTGGGCATACAGAGCTTGTCTATGTGACCGAGCCAGGAGAATATCATATTGTTGGAGAAACACGT
GATGACGCAGTTGGTGAGGCCTATGATAAGGTAGGACGTGTGATGGGCTTGCCCTATCCTGCTGGTCGTGAGATTGATCA
GCTAGCTCACCAAGGGACAGATACCTATCATTTTCCTCGTGCCATGATGAAAGAGGATCATTTAGAATTTTCTTTTTCAG
GCCTACAATCAGCCTTTATCAACCTGCACCATAATGCGCAGCAAAAGGGTGAGGAGCTTGTGCTTGAGGATCTTTGTGCT
TCCTTTCAGGCTGCGGTGTTAGATATATTGTTAGCAAAAACGAAGAAGGCACTCAAGCAGTACCCATCAAAAATGCTAGT
CGTTGCAGGTGGAGTGGCAGCTAATCAGGGACTTCGTGAGCGTTTGGCCAAGGAAATAACGGATTTAGCTGTGGTTATTC
CTCCATTAAGGTTGTGTGGGGATAACGCTGGTATGATTGCCTTAGCAGCGGCTGTTGAGTATGATAAAGGGCATGTGGCA
GACTTGGACCTAAATGCTAAGCCAAGTCTAGCCTTTGAGAGCTTTCATCAGCAGTAG

Upstream 100 bases:

>100_bases
CAGCTTTATCTCAAGCATGGCTTTGAGGTGATAGGCCAGCGTAACAATTATTACCATGATCCAATAGAAGCAGCCTTGAT
CATGAGGCGGGAAGGAAAGA

Downstream 100 bases:

>100_bases
TATTAGTATGAGGAGATTGTCATGTTTTATTTATTGCTTCCCCCATTGATTTGCAGTGTGGTATTTTTGGCTGTCTATAT
TAAGGAGCCAAGAACGCTGT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTDRYILAVESSCDETSVAVLKNDNVLLTNIIASQVESHKRFGGVVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVA
VTYGPGLVGALLVGLAAAKAFAWANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLQSAFINLHHNAQQKGEELVLEDLCA
SFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQGLRERLAKEITDLAVVIPPLRLCGDNAGMIALAAAVEYDKGHVA
DLDLNAKPSLAFESFHQQ

Sequences:

>Translated_338_residues
MTDRYILAVESSCDETSVAVLKNDNVLLTNIIASQVESHKRFGGVVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVA
VTYGPGLVGALLVGLAAAKAFAWANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLQSAFINLHHNAQQKGEELVLEDLCA
SFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQGLRERLAKEITDLAVVIPPLRLCGDNAGMIALAAAVEYDKGHVA
DLDLNAKPSLAFESFHQQ
>Mature_337_residues
TDRYILAVESSCDETSVAVLKNDNVLLTNIIASQVESHKRFGGVVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVAV
TYGPGLVGALLVGLAAAKAFAWANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETRD
DAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLQSAFINLHHNAQQKGEELVLEDLCAS
FQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQGLRERLAKEITDLAVVIPPLRLCGDNAGMIALAAAVEYDKGHVAD
LDLNAKPSLAFESFHQQ

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=329, Percent_Identity=32.8267477203647, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI8923380, Length=323, Percent_Identity=32.8173374613003, Blast_Score=132, Evalue=5e-31,
Organism=Escherichia coli, GI1789445, Length=327, Percent_Identity=44.954128440367, Blast_Score=267, Evalue=7e-73,
Organism=Caenorhabditis elegans, GI17557464, Length=329, Percent_Identity=30.3951367781155, Blast_Score=134, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI71995670, Length=324, Percent_Identity=31.1728395061728, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320099, Length=353, Percent_Identity=33.1444759206799, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6322891, Length=296, Percent_Identity=30.7432432432432, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI20129063, Length=333, Percent_Identity=34.2342342342342, Blast_Score=178, Evalue=4e-45,
Organism=Drosophila melanogaster, GI21357207, Length=326, Percent_Identity=30.9815950920245, Blast_Score=137, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36478; Mature: 36347

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRYILAVESSCDETSVAVLKNDNVLLTNIIASQVESHKRFGGVVPEVASRHHVEVITT
CCCCEEEEEECCCCCCEEEEEECCCEEEHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHH
CFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFAWANDLPLIPVNHMAGHLM
HHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHH
AAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETRDDAVGEAYDKVGRVMGLPYP
HHHCCCCCCCCHHHHEECCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCC
AGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLQSAFINLHHNAQQKGEELVLEDLCA
CCCCHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQGLRERLAKEITDLAVVIPPLRLCG
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
DNAGMIALAAAVEYDKGHVADLDLNAKPSLAFESFHQQ
CCCCCEEEEEEEECCCCCEEEECCCCCCCHHHHHHCCC
>Mature Secondary Structure 
TDRYILAVESSCDETSVAVLKNDNVLLTNIIASQVESHKRFGGVVPEVASRHHVEVITT
CCCEEEEEECCCCCCEEEEEECCCEEEHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHH
CFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFAWANDLPLIPVNHMAGHLM
HHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHH
AAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETRDDAVGEAYDKVGRVMGLPYP
HHHCCCCCCCCHHHHEECCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCC
AGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLQSAFINLHHNAQQKGEELVLEDLCA
CCCCHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQGLRERLAKEITDLAVVIPPLRLCG
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
DNAGMIALAAAVEYDKGHVADLDLNAKPSLAFESFHQQ
CCCCCEEEEEEEECCCCCEEEECCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA