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The map label for this gene is nanE [H]

Identifier: 195977392

GI number: 195977392

Start: 267380

End: 268105

Strand: Direct

Name: nanE [H]

Synonym: Sez_0245

Alternate gene names: 195977392

Gene position: 267380-268105 (Clockwise)

Preceding gene: 195977391

Following gene: 195977393

Centisome position: 13.21

GC content: 50.14

Gene sequence:

>726_bases
ATGCTTGAAAAACCAAGCAAGGCAGAGCTACTGGCAGCTCTGAAGGACGGGCTGATCGTTTCCTGTCAAGCTCTGCCGGG
CGAGCCTCTCTATTCAGAGGCAGGAGGTATCATGCCTCTGATGGCAAAGGCAGCAGAGGAAGCAGGAGCAGTAGGGATAC
GAGCCAATGGTGTTCGAGATATTAAGGAAATCCAAGCGGTGACGGATCTGCCAATCATAGGGATCATCAAAAAGGAGTAT
CCTCCGCAAGCGCCCTTTATCACGCCAACCATGGTAGAGGTAGATGCCTTAGCGGCCTTAGGTGTAGCGGTGATAGCCTT
GGATTGTACGCAAAGGGAGCGTCATGATGGCTTAGCGATAGTGGATTTTATTCGAGCGATAAGGAAGAAGTACCCAGAGC
AGCTGTTTATGGCAGACATCAGTACGCTTGAAGAGGGTCTAGCAGCCTATGAGGCTGGTATAGATTTTGTAGGGACGACC
TTATCAGGGTATACGCCCTATAGTCGTCAGGGGACAGGTCCGGATATGGAGCTGATAAGTGCCTTGTGTGATGCAGGGGT
ATCAGTGATAGCTGAGGGCAAGATTCATAGTCCAGAGGAGGCCAGGGCTGTTCAGGCCTTGGGAGTAGCTGGTATTGTGG
TTGGTGGTGCTATTACCAGACCAAAGGAAATTGCAGAGCGCTTTGTGGCGGCTTTGACATCGTCATTGTCTATAAAAAAA
TATTAA

Upstream 100 bases:

>100_bases
AAAGTAGTTTCTAAAACCAGAGGAAGTATTGAAAACGCTTTAATATCTGCTACAATAAAGATGTGAACGTTCTCTAAAAC
TAATAAAAGGAGTAGAAAGC

Downstream 100 bases:

>100_bases
TATAAAGGAGAATTTACAATGAAAATGAAGAAATTAGCTTCATTTGTGATGCTTGGAGCATCTGTTTTAGGGTTAGCAGC
CTGTGGCAGTAGCAGCAAGG

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MLEKPSKAELLAALKDGLIVSCQALPGEPLYSEAGGIMPLMAKAAEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEY
PPQAPFITPTMVEVDALAALGVAVIALDCTQRERHDGLAIVDFIRAIRKKYPEQLFMADISTLEEGLAAYEAGIDFVGTT
LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAITRPKEIAERFVAALTSSLSIKK
Y

Sequences:

>Translated_241_residues
MLEKPSKAELLAALKDGLIVSCQALPGEPLYSEAGGIMPLMAKAAEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEY
PPQAPFITPTMVEVDALAALGVAVIALDCTQRERHDGLAIVDFIRAIRKKYPEQLFMADISTLEEGLAAYEAGIDFVGTT
LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAITRPKEIAERFVAALTSSLSIKK
Y
>Mature_241_residues
MLEKPSKAELLAALKDGLIVSCQALPGEPLYSEAGGIMPLMAKAAEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEY
PPQAPFITPTMVEVDALAALGVAVIALDCTQRERHDGLAIVDFIRAIRKKYPEQLFMADISTLEEGLAAYEAGIDFVGTT
LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAITRPKEIAERFVAALTSSLSIKK
Y

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential) [H]

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family [H]

Homologues:

Organism=Escherichia coli, GI1789617, Length=225, Percent_Identity=40.8888888888889, Blast_Score=124, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060 [H]

Pfam domain/function: PF04131 NanE [H]

EC number: =5.1.3.9 [H]

Molecular weight: Translated: 25392; Mature: 25392

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKPSKAELLAALKDGLIVSCQALPGEPLYSEAGGIMPLMAKAAEEAGAVGIRANGVRD
CCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHCCCCEECCCHHH
IKEIQAVTDLPIIGIIKKEYPPQAPFITPTMVEVDALAALGVAVIALDCTQRERHDGLAI
HHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHH
VDFIRAIRKKYPEQLFMADISTLEEGLAAYEAGIDFVGTTLSGYTPYSRQGTGPDMELIS
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCHHHHH
ALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAITRPKEIAERFVAALTSSLSIKK
HHHHCCHHEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
Y
C
>Mature Secondary Structure
MLEKPSKAELLAALKDGLIVSCQALPGEPLYSEAGGIMPLMAKAAEEAGAVGIRANGVRD
CCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHCCCCEECCCHHH
IKEIQAVTDLPIIGIIKKEYPPQAPFITPTMVEVDALAALGVAVIALDCTQRERHDGLAI
HHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHH
VDFIRAIRKKYPEQLFMADISTLEEGLAAYEAGIDFVGTTLSGYTPYSRQGTGPDMELIS
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCHHHHH
ALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAITRPKEIAERFVAALTSSLSIKK
HHHHCCHHEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]