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The map label for this gene is oxaA1 [H]

Identifier: 195977384

GI number: 195977384

Start: 260613

End: 261422

Strand: Direct

Name: oxaA1 [H]

Synonym: Sez_0237

Alternate gene names: 195977384

Gene position: 260613-261422 (Clockwise)

Preceding gene: 195977383

Following gene: 195977385

Centisome position: 12.88

GC content: 44.57

Gene sequence:

>810_bases
TTGAAAAAAAGAGTTAAAACAGCAGCCCTAGTGCCGCTTGTCTTGCTCCTAGTAGCCTGTGGGCGTGGAGAGGTGACAGC
ACAATCATCTAGCAGCTGGGAGCAATTGGTTTATTTTTTTGCCAAGGCGATCCAATGGTTGTCCTTTGATGGATCGACTG
GGATTGGGATTATCCTATTTACGATAATGATTCGCTTACTTTTACTGCCATTGTTTAACATGCAAATCAAGTCAGGGCAG
AAAATGCAGGACATTCAGCCAGAGCTAAAGGCCCTGCAGAAAAAATACGCCGCTAAGGACACAGCAACTCGTATGAAGCT
AGCTGAGGAAAGTCAAGCTCTGTACAAAAAGTATGGTGTCAATCCTTACATGAGCCTTTTGCCCTTGCTGATTCAGATGC
CGGTGATGTTCGCCTTGTTTCAGTCCCTGTCTCGTGTGGCCTTCTTAAGAGAAGGAACCTTTTTATGGGTTGAGCTGGCG
CGACACGATCATCTCTTTATCCTGCCTATTTTAGCGGCTGTCTTTACCTTTTTATCAACATGGCTAACCAATCTAGCGGC
TAGAGAAAAGACGGCTATGATAACGATCATGACCTACGTGATGCCTATATTCATCTTCTTTATGGGCTTTAATCTGGCCA
GTGGTGTGGTGCTTTATTGGGCGGTTTCCAATGCCTTTCAGGTTGTTCAGCTCTTGTTGTTTAATAATCCCTTTAAAGTT
ATTGCCGAAAGGCAGCGTTTAGCAGATGAAGAAAAAGAGCGTCGAGCTAAGGAACGTCGCGCTCGTAAGAGAGCAATGAA
AAGAAAATAG

Upstream 100 bases:

>100_bases
ATTGCTAGGAGAGGTGCAGAGGAATTAGATTATCAAGCAGTCAAACAAAATTTACATCATGTTTTAAAGCTAGCAAAATT
GCTTGAGGAAGGTTTTGAGA

Downstream 100 bases:

>100_bases
GAGTTTAGGATATGGTATTGTTTACAGGTAAGACTGTTGAAGAAGCAATTGAAAAAGGACTTCAAGAGTTGGGGTTGTCA
CGTCTAAAAGCACATATCAA

Product: membrane protein OxaA 1 precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAIQWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQ
KMQDIQPELKALQKKYAAKDTATRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLSRVAFLREGTFLWVELA
RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPIFIFFMGFNLASGVVLYWAVSNAFQVVQLLLFNNPFKV
IAERQRLADEEKERRAKERRARKRAMKRK

Sequences:

>Translated_269_residues
MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAIQWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQ
KMQDIQPELKALQKKYAAKDTATRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLSRVAFLREGTFLWVELA
RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPIFIFFMGFNLASGVVLYWAVSNAFQVVQLLLFNNPFKV
IAERQRLADEEKERRAKERRARKRAMKRK
>Mature_269_residues
MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAIQWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQ
KMQDIQPELKALQKKYAAKDTATRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLSRVAFLREGTFLWVELA
RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPIFIFFMGFNLASGVVLYWAVSNAFQVVQLLLFNNPFKV
IAERQRLADEEKERRAKERRARKRAMKRK

Specific function: Required for the insertion of integral membrane proteins into the membrane. May also be involved in protein secretion processes [H]

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=228, Percent_Identity=32.4561403508772, Blast_Score=100, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321002, Length=184, Percent_Identity=27.7173913043478, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24662345, Length=194, Percent_Identity=25.7731958762887, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356443, Length=194, Percent_Identity=25.7731958762887, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001708
- InterPro:   IPR023060 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 30899; Mature: 30899

Theoretical pI: Translated: 10.86; Mature: 10.86

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAIQWLSFDGSTGIGIILF
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
TIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTATRMKLAEESQALYKKYGV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NPYMSLLPLLIQMPVMFALFQSLSRVAFLREGTFLWVELARHDHLFILPILAAVFTFLST
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
WLTNLAAREKTAMITIMTYVMPIFIFFMGFNLASGVVLYWAVSNAFQVVQLLLFNNPFKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IAERQRLADEEKERRAKERRARKRAMKRK
HHHHHHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAIQWLSFDGSTGIGIILF
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
TIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTATRMKLAEESQALYKKYGV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NPYMSLLPLLIQMPVMFALFQSLSRVAFLREGTFLWVELARHDHLFILPILAAVFTFLST
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
WLTNLAAREKTAMITIMTYVMPIFIFFMGFNLASGVVLYWAVSNAFQVVQLLLFNNPFKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IAERQRLADEEKERRAKERRARKRAMKRK
HHHHHHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]