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The map label for this gene is tadA [H]

Identifier: 195977341

GI number: 195977341

Start: 214126

End: 214620

Strand: Direct

Name: tadA [H]

Synonym: Sez_0194

Alternate gene names: 195977341

Gene position: 214126-214620 (Clockwise)

Preceding gene: 195977340

Following gene: 195977344

Centisome position: 10.58

GC content: 48.28

Gene sequence:

>495_bases
ATGAGCTATTCCAAACAAGAGCAAGAGTATTTTATGCGAGAAGCCCTCAAGGAGGCTAAGAAATCTCTGCTAAAGGACGA
GATACCGATCGGCTGCGTTATTGTGAAGGCTGGTCACATTATCGGGCGTGGTCACAATGCTCGTGAGGAGCGCAATCAGG
CGATTATGCATGCTGAGATCATGGCTATTAGTGAAGCCAATGTGCATGAAGGCAATTGGCGTCTCTTGGATACGACTCTT
TTTGTGACGATTGAGCCTTGTGTCATGTGCAGCGGAGCCATTGGGCTAGCCCGAATTCCTCATGTGGTCTATGGCGCTAG
CAATCAAAAATTTGGCGGTGCTGGTAGTCTTTATCAGATCTTAACCGATGAGCGCCTGAACCATCGTGTGCAGCTTGAAA
CGGGTCTTTTAGCTGACGACTGTGCCAAGCTCATGCAGACCTTTTTCCAGCAAAAGCGTGACCAGAAAAAGCAGGATAAG
GAAAGCAAGACCTAG

Upstream 100 bases:

>100_bases
ATTTGGAGGTGCTGCGACAGCAAGCTCAAAGCTATGCTGGTCAGATTCCTGTTGATCTTGCTCTGCCACATCGAACTTGG
GATTTGGGGAGCCTATCTCA

Downstream 100 bases:

>100_bases
CCCGTTGAGCGATTAGCAAGAAAAAAGCCCCTTGAGAGCTTAGCATAGCTTTTTAATGGCTGGTAGAGCCATGTTATAAG
CGTTTGCGCTTGTCTGTCAG

Product: tRNA-specific adenosine-34 deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MSYSKQEQEYFMREALKEAKKSLLKDEIPIGCVIVKAGHIIGRGHNAREERNQAIMHAEIMAISEANVHEGNWRLLDTTL
FVTIEPCVMCSGAIGLARIPHVVYGASNQKFGGAGSLYQILTDERLNHRVQLETGLLADDCAKLMQTFFQQKRDQKKQDK
ESKT

Sequences:

>Translated_164_residues
MSYSKQEQEYFMREALKEAKKSLLKDEIPIGCVIVKAGHIIGRGHNAREERNQAIMHAEIMAISEANVHEGNWRLLDTTL
FVTIEPCVMCSGAIGLARIPHVVYGASNQKFGGAGSLYQILTDERLNHRVQLETGLLADDCAKLMQTFFQQKRDQKKQDK
ESKT
>Mature_163_residues
SYSKQEQEYFMREALKEAKKSLLKDEIPIGCVIVKAGHIIGRGHNAREERNQAIMHAEIMAISEANVHEGNWRLLDTTLF
VTIEPCVMCSGAIGLARIPHVVYGASNQKFGGAGSLYQILTDERLNHRVQLETGLLADDCAKLMQTFFQQKRDQKKQDKE
SKT

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=176, Percent_Identity=34.0909090909091, Blast_Score=111, Evalue=3e-25,
Organism=Escherichia coli, GI145693172, Length=164, Percent_Identity=43.2926829268293, Blast_Score=147, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17541138, Length=148, Percent_Identity=35.1351351351351, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17554608, Length=128, Percent_Identity=34.375, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322425, Length=168, Percent_Identity=29.7619047619048, Blast_Score=83, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325319, Length=160, Percent_Identity=34.375, Blast_Score=73, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355527, Length=148, Percent_Identity=32.4324324324324, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 18506; Mature: 18374

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSKQEQEYFMREALKEAKKSLLKDEIPIGCVIVKAGHIIGRGHNAREERNQAIMHAEI
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEECCCCCHHHHHHHHHHHHH
MAISEANVHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHVVYGASNQKFGGAGSLYQI
HEECCCCCCCCCEEEEEEEEEEEECHHHHHCCCHHHHHCCHHEECCCCCCCCCCCHHHHH
LTDERLNHRVQLETGLLADDCAKLMQTFFQQKRDQKKQDKESKT
HHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SYSKQEQEYFMREALKEAKKSLLKDEIPIGCVIVKAGHIIGRGHNAREERNQAIMHAEI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEECCCCCHHHHHHHHHHHHH
MAISEANVHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHVVYGASNQKFGGAGSLYQI
HEECCCCCCCCCEEEEEEEEEEEECHHHHHCCCHHHHHCCHHEECCCCCCCCCCCHHHHH
LTDERLNHRVQLETGLLADDCAKLMQTFFQQKRDQKKQDKESKT
HHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]