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The map label for this gene is furR [H]

Identifier: 195977331

GI number: 195977331

Start: 200176

End: 200649

Strand: Direct

Name: furR [H]

Synonym: Sez_0184

Alternate gene names: 195977331

Gene position: 200176-200649 (Clockwise)

Preceding gene: 195977330

Following gene: 195977332

Centisome position: 9.89

GC content: 42.41

Gene sequence:

>474_bases
TTGGACATTCATTCACATCAGCAAGCTCTAAATGCCTATGAAAATGTCCTAGAGCATCTACGTGACAAGCATATTCGTAT
TACCGAGACGCGTAAGGCGATCATTTCGTACATGATTCAGTCCACTGAGCACCCTAGCGCAGACAAAATCTATCGTGATT
TACAGCCTCAATACCCTAATATGAGCCTTGCTACGGTGTATAATAATTTGAAGGTTCTTGTTGATGAGGGCTTTGTATCT
GAGCTGAAAATTAGTAATGATTTGACGACCTATTATGACTTTATGGGACATCAGCATGTCAATGTTGTTTGTGAGGTCTG
CGGGACAATCGCTGATTTTATGGACGTAGATGTAATGGATATCGCTAAAGAAGCACACCAGCAAACAGGCTATAAGGTCA
CCCGTATTCCAGTTATAGCCTACGGTGTTTGCCCTAGCTGTCAGGCTAAGCAGGACAAGGATACAGACTATTGA

Upstream 100 bases:

>100_bases
GAATCGCTGTATCAAGATTGACTATTTACAGCTGATCACTAAGCAGGATCAAGATTCCTGCTAGTTAGCGCCACAGTTAC
AAAAGGAGGAGGTTGTAAGC

Downstream 100 bases:

>100_bases
GGGTTGGTTTTTTGGATCTTGGCTGCTCGTGTAGCTGATGATATGGTATAAAGCCTAGAAGAGAGAGTTGGAGACTCGCT
CTTTTTTTGTTGGCTGAAAA

Product: Ferric uptake regulator Fur

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEHPSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVS
ELKISNDLTTYYDFMGHQHVNVVCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQAKQDKDTDY

Sequences:

>Translated_157_residues
MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEHPSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVS
ELKISNDLTTYYDFMGHQHVNVVCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQAKQDKDTDY
>Mature_157_residues
MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEHPSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVS
ELKISNDLTTYYDFMGHQHVNVVCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQAKQDKDTDY

Specific function: Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins. May act as a hydrogen peroxide and organic hydroperoxide sensor [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18001; Mature: 18001

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEHPSADKIYRDLQPQYPN
CCCCHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCC
MSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNVVCEVCGTIADFMDVDVMD
CHHHHHHHHHHEEECCCCHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHH
IAKEAHQQTGYKVTRIPVIAYGVCPSCQAKQDKDTDY
HHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEHPSADKIYRDLQPQYPN
CCCCHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCC
MSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNVVCEVCGTIADFMDVDVMD
CHHHHHHHHHHEEECCCCHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHH
IAKEAHQQTGYKVTRIPVIAYGVCPSCQAKQDKDTDY
HHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA