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The map label for this gene is ruvB [H]

Identifier: 195977191

GI number: 195977191

Start: 49069

End: 50070

Strand: Direct

Name: ruvB [H]

Synonym: Sez_0037

Alternate gene names: 195977191

Gene position: 49069-50070 (Clockwise)

Preceding gene: 195977190

Following gene: 195977193

Centisome position: 2.42

GC content: 43.71

Gene sequence:

>1002_bases
ATGACAAGAATTTTAGATAATGATCTGATAGGCGATGAAGGATCTGTTGAGAGGACACTACGTCCACAGTATTTACGTGA
GTATATTGGTCAGGATAGGGTTAAAGACCAGCTGATGATTTTTATTGAGGCAGCCAAGAGGCGTGAGGAATCCTTGGATC
ATGTCCTGTTATTTGGTCCCCCAGGCTTGGGTAAAACAACGATGGCCTTTGTCATTGCCAATGAATTGGGAGTTCATCTC
AAGCAGACCTCTGGCCCAGCCATTGAAAAAGCTGGCGATTTGGTGGCAATTTTGAATGATTTAGAGCCAGGAGATGTCCT
CTTTATTGATGAAATTCATCGTATGCCGATGACTGTTGAGGAAATCTTGTACAGTGCCATGGAGGATTTTTACATTGATA
TCATGATTGGCGCTGGAGACACTAGCCGGAGTGTGCATTTGGAGCTGCCTCCCTTTACATTAATTGGAGCAACGACTCGT
GCAGGCATGCTGTCAAATCCTTTGAGGGCTCGTTTTGGGATTACTGGGCATATGGAATATTATCAGACAGCTGATTTAAC
AGAGATTGTGGAGCGTACAGCTGATATTTTTGACATGACAATCAAGCATGAGGCCGCTTATGAGCTGGCACGCAGAAGTC
GTGGAACCCCTCGTATTGCTAATCGGCTGTTAAAAAGGGTGCGTGATTATGCTCAAATTATGGGTGATGGAATGATTACG
ACTCAAATCACAGATAAGGCTCTAACGATGTTAGATGTGGATCAAGAAGGTTTAGATTATGTGGACCAAAAGATTCTTCG
TACCATGATTGAGGTGTATCAGGGAGGGCCGGTTGGTCTAGGGACTCTATCTGTCAATATAGCAGAGGAGCGAGATACAG
TAGAAGACATGTACGAGCCTTATTTAATTCAAAAGGGTTTTATCATGCGTACCAGAACAGGTCGAGTTGTAACCGAAAAG
GCCTATCAGCACTTAGGCTATCCCTATGAGAAAAAACACTAA

Upstream 100 bases:

>100_bases
AGCTGCTTTATTTCTACTTCATTCTGCCCAATTACTTAGTGATATTGACTGGTGGCGTGTTGGTTAAAGCTAAATCATCT
ATTTATGCTATAATAGCTCT

Downstream 100 bases:

>100_bases
GACATAAATAGCTATGTAAGACTTGATTCCTTTGTTTTTACCGGTGTCAAGTCTTTTGTATTGTCAATAGCTAGCTTAAT
AAGCCTAATGGCTACTGAGA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEAAKRREESLDHVLLFGPPGLGKTTMAFVIANELGVHL
KQTSGPAIEKAGDLVAILNDLEPGDVLFIDEIHRMPMTVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPRIANRLLKRVRDYAQIMGDGMIT
TQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGGPVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEK
AYQHLGYPYEKKH

Sequences:

>Translated_333_residues
MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEAAKRREESLDHVLLFGPPGLGKTTMAFVIANELGVHL
KQTSGPAIEKAGDLVAILNDLEPGDVLFIDEIHRMPMTVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPRIANRLLKRVRDYAQIMGDGMIT
TQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGGPVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEK
AYQHLGYPYEKKH
>Mature_332_residues
TRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEAAKRREESLDHVLLFGPPGLGKTTMAFVIANELGVHLK
QTSGPAIEKAGDLVAILNDLEPGDVLFIDEIHRMPMTVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTRA
GMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPRIANRLLKRVRDYAQIMGDGMITT
QITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGGPVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEKA
YQHLGYPYEKKH

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=314, Percent_Identity=57.6433121019108, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37709; Mature: 37578

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEAAKRREESLDHVLLFGP
CCCCCCCCCCCCCCCCHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEECC
PGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLEPGDVLFIDEIHRMPMTVE
CCCCHHHHHHHHHHHHCCEEECCCCCCHHHCCCEEEEECCCCCCCEEEEEHHHCCCCCHH
EILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTRAGMLSNPLRARFGITGHMEY
HHHHHHHHCEEEEEEEECCCCCCEEEEECCCEEEEECCHHCCHHCCCHHHHCCCCCCHHH
YQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPRIANRLLKRVRDYAQIMGDGMIT
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEE
TQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGGPVGLGTLSVNIAEERDTVEDMYEP
EEEHHHHHEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECHHHHHHHHHHCC
YLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKKH
HHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEAAKRREESLDHVLLFGP
CCCCCCCCCCCCCCCHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEECC
PGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLEPGDVLFIDEIHRMPMTVE
CCCCHHHHHHHHHHHHCCEEECCCCCCHHHCCCEEEEECCCCCCCEEEEEHHHCCCCCHH
EILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTRAGMLSNPLRARFGITGHMEY
HHHHHHHHCEEEEEEEECCCCCCEEEEECCCEEEEECCHHCCHHCCCHHHHCCCCCCHHH
YQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPRIANRLLKRVRDYAQIMGDGMIT
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEE
TQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGGPVGLGTLSVNIAEERDTVEDMYEP
EEEHHHHHEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECHHHHHHHHHHCC
YLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKKH
HHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA