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The map label for this gene is engD [H]

Identifier: 195977161

GI number: 195977161

Start: 3723

End: 4838

Strand: Direct

Name: engD [H]

Synonym: Sez_0005

Alternate gene names: 195977161

Gene position: 3723-4838 (Clockwise)

Preceding gene: 195977160

Following gene: 195977162

Centisome position: 0.18

GC content: 42.47

Gene sequence:

>1116_bases
ATGGCTTTAACAGCAGGCATCGTTGGTTTGCCAAACGTTGGGAAATCAACCTTATTTAACGCAATTACAAAAGCAGGGGC
AGAGGCTGCTAATTATCCTTTTGCGACAATTGATCCTAATGTTGGTATGGTAGAGGTTCCAGATGAGCGTTTACAGAAGT
TGACAGAGCTTATCACGCCTAAAAAAACAGTACCTACAACCTTTGAATTTACAGATATCGCAGGTATTGTAAAGGGAGCT
TCAAAAGGAGAAGGACTTGGAAATAAGTTCTTAGCCAATATCCGCGAGGTTGATGCTATTGTTCATGTGGTTCGTGCCTT
TGATGATGAAAATGTCATGCGTGAGCAAGGGCGTGAGGATGCCTTTGTGGATCCTTTGGCAGATATTGATACGATTAACC
TTGAATTAATTTTGGCTGACTTAGAATCAATCAATAAACGCTATGCGCGTGTCGAAAAAATGGCCCGTACACAAAAGGAC
AAGGATTCTGTAGCAGAATTTGCTGTTCTTGAAAAAATTAAGCCAGTGCTTGAAGAAGGTAAATCTGCTCGTACCATTAG
CTTTACAGATGATGAGCAAAAAATTGTTAGGCAGTTATTTTTATTAACGACTAAGCCAGTGCTTTATGTGGCAAACGTTG
ATGAGGATAAGGTAGCAACTCCAGACGCTATTGATTATGTGAAGCAGATTCGTGACTTTGCAGCAACTGAAAACGCAGAG
GTCGTTGTGATTTCAGCTCGTGCAGAAGAAGAGATTTCAGAGCTAGATGATGAAGATAAGCTCGAATTTTTAGAGGCTAT
CGGTCTGACAGAATCTGGTGTTGACAAGCTGACACGTGCAGCCTATCATTTGCTTGGACTTGGGACCTACTTTACAGCTG
GTGAAAAGGAAGTGCGTGCATGGACCTTCAAGCGCGGCATTAAGGCACCGCAAGCGGCTGGTATCATTCACTCAGATTTT
GAGCGCGGTTTTATTCGTGCGGTGACGATGAGCTATGATGATTTGATTAAGTATGGCTCAGAAAAGGCTGTTAAAGAGGC
AGGTCGTCTGCGTGAGGAAGGAAAGGAATATATCGTTCAGGATGGCGATATTATGGAGTTTAGATTCAACGTTTAG

Upstream 100 bases:

>100_bases
TGATCTATTTTAGTTAAAGATCATTACTAGGCAAGCTTTTTCTTCTTTTTTTTGCTATAATGATAGGGATTGAAAAAATG
TAACGGAGACCGAAAAAAAT

Downstream 100 bases:

>100_bases
TGATAACAATATCGTGTTCTAGGGTTGGGATAGTATTCCAGCCCTTTTGGTGCCTATCAAAAGCTTAGAAAGGATAAAAA
TAGTGGGGAAGAAGCTGATA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGA
SKGEGLGNKFLANIREVDAIVHVVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKVATPDAIDYVKQIRDFAATENAE
VVVISARAEEEISELDDEDKLEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDF
ERGFIRAVTMSYDDLIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV

Sequences:

>Translated_371_residues
MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGA
SKGEGLGNKFLANIREVDAIVHVVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKVATPDAIDYVKQIRDFAATENAE
VVVISARAEEEISELDDEDKLEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDF
ERGFIRAVTMSYDDLIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV
>Mature_370_residues
ALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGAS
KGEGLGNKFLANIREVDAIVHVVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKDK
DSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKVATPDAIDYVKQIRDFAATENAEV
VVISARAEEEISELDDEDKLEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFE
RGFIRAVTMSYDDLIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=380, Percent_Identity=42.1052631578947, Blast_Score=291, Evalue=7e-79,
Organism=Homo sapiens, GI58761502, Length=226, Percent_Identity=38.9380530973451, Blast_Score=154, Evalue=1e-37,
Organism=Escherichia coli, GI1787454, Length=371, Percent_Identity=54.7169811320755, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1789574, Length=145, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=371, Percent_Identity=42.0485175202156, Blast_Score=289, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6319499, Length=383, Percent_Identity=41.77545691906, Blast_Score=261, Evalue=9e-71,
Organism=Saccharomyces cerevisiae, GI6321773, Length=388, Percent_Identity=36.5979381443299, Blast_Score=207, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6321649, Length=246, Percent_Identity=31.7073170731707, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321962, Length=179, Percent_Identity=28.4916201117318, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24640873, Length=375, Percent_Identity=41.0666666666667, Blast_Score=265, Evalue=4e-71,
Organism=Drosophila melanogaster, GI24640877, Length=375, Percent_Identity=41.0666666666667, Blast_Score=265, Evalue=4e-71,
Organism=Drosophila melanogaster, GI24640875, Length=375, Percent_Identity=41.0666666666667, Blast_Score=265, Evalue=4e-71,
Organism=Drosophila melanogaster, GI24640879, Length=334, Percent_Identity=38.9221556886228, Blast_Score=213, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24585318, Length=174, Percent_Identity=29.8850574712644, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 41133; Mature: 41002

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTELITP
CCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCEEECCCCCEEECCHHHHHHHHHHHCC
KKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVHVVRAFDDENVMREQGRED
CCCCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
AFVDPLADIDTINLELILADLESINKRYARVEKMARTQKDKDSVAEFAVLEKIKPVLEEG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
KSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKVATPDAIDYVKQIRDFAATENAE
CCCEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCC
VVVISARAEEEISELDDEDKLEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRA
EEEEECCCHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
WTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDDLIKYGSEKAVKEAGRLREEGKEYIVQ
HHHHHCCCCCHHCCCHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHCHHHEEC
DGDIMEFRFNV
CCCEEEEEECC
>Mature Secondary Structure 
ALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTELITP
CCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCEEECCCCCEEECCHHHHHHHHHHHCC
KKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVHVVRAFDDENVMREQGRED
CCCCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
AFVDPLADIDTINLELILADLESINKRYARVEKMARTQKDKDSVAEFAVLEKIKPVLEEG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
KSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKVATPDAIDYVKQIRDFAATENAE
CCCEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCC
VVVISARAEEEISELDDEDKLEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRA
EEEEECCCHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
WTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDDLIKYGSEKAVKEAGRLREEGKEYIVQ
HHHHHCCCCCHHCCCHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHCHHHEEC
DGDIMEFRFNV
CCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]