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The map label for this gene is yaaU [H]

Identifier: 195953069

GI number: 195953069

Start: 627302

End: 628681

Strand: Direct

Name: yaaU [H]

Synonym: HY04AAS1_0694

Alternate gene names: 195953069

Gene position: 627302-628681 (Clockwise)

Preceding gene: 195953049

Following gene: 195953070

Centisome position: 40.22

GC content: 39.28

Gene sequence:

>1380_bases
ATGGCAAAAGTTGTCAAAGGTAGTATAGCAGAAGCTTTAAACACTTCGCAGTTTAGTCTTTTTCACATCAAGGCTATGTT
TGCTTCAGCCATGGGATTTTTTACATCGGCTTACGACTTGTTCATAATAGGTACTGCCCTTGTGCTAATAAAAGATGAAT
GGCACCTAAGCGCCCAACAAGTAGGTCTTATAGGTTCTATATCTCTTATAGCTACTTTCTTTGGTGCTTTTATCTTTGGA
AATCTCGCAGACAGGCTTGGTAGAAAATCTGTTTACGGCATAGAAGCTATTTTGATGGTTTTAGGCGCTTTAATGTCCGC
TTTTTCTTTTAACGTAGGCTTTTTACTTTTATCTCGTTTTATATTGGGCTTAGGAGTAGGGGGAGATTATCCTCTTTCTG
CGGTTATAATGAGCGAGTATGCAAACACTACCACAAGAGGTAGAATGGTTACATTGGTATTTAGCGCTCAGGCACTGGGT
TTGATAGCTGGACCTATGGTGGCGCTCACTCTTTTGGCGGCTGGAGTAGACAAAGATTTAGCCTGGAGAATAATGCTTGG
GCTAGGTGCCTTACCAGCAGCTACGGTTATATATTTAAGAAGAAGGTTACCAGAATCCCCAAGATGGCTTGCAAGAGTTA
AAGGTGAGAAAGAAGTGGCGGCAAAAGATTTAGCATCGTTTTCACTTGGTGATATAGTCATAGAAGAAGTCAAAGACCAG
ATAGTCAAAAAACCTTTATCAAAATATTGGTTACAGCTTTTAGGTACCGCTGGTACATGGTTTTTGTTTGACTACGCTTA
CTATGGCAACACTATATCAACACCTTTAGTACTAAAACATATAGCAACCCATGCAAATTTAATACAAAGTACAGCTATAA
GCTTTCTAATATTTGTGGTATTTGCTGTACCTGGTTATTTCATAGCCGCTGCCACTATAGACAAAATAGGACATAAATTT
TTGCAAATGCTTGGATTTTTCATGATGGGTCTTATGTTTTTCATAATAGGAATGTTTCCTTCAATAGTACACAATTTTCC
TCTTTTCGTAACGTTGTATGGTTTGTCTTACTTCTTTGCAGAGTTTGGCCCAAATACCACCACCTTTGTATTGCCAGCGG
AGGTATTTCCAGTAAACGTTAGAACCACAGCCCATGGTATATCTGCTGGCGTAGCTAAGATAGGCGCATTCATAGGAGCT
TACTTCTTCCCAATCTTGTTAAAGTCGTTGGGATTAAGCCATACCTTGCTTTTGACATTTGTATTCTCGTTAGCTGGACT
AATACTTACTTATATAGCAATCCCAGAACCAAAAGGAAAATCTTTGGAAGAAGTATCTCAAGAAGATACGACCCTTTCAA
AGCCCTCACCTGCTACCTAA

Upstream 100 bases:

>100_bases
ATTTTTATATTTTTCCTTTATAATTTTTTTACAAGTTTTTAATCAAATATTAACAATAAACCTTTAAAATGCTAAAGTAT
TAAGCGTTAGGAGGTTTAAT

Downstream 100 bases:

>100_bases
CATATAAAAATAGCCCCGTTTGGGGCTTTTAAAATTAACAAAAAATTAAAAATAAAAGTTTAATATAAAGATATGAAATA
TGTAAAGTTTTTTTACAAAA

Product: General substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MAKVVKGSIAEALNTSQFSLFHIKAMFASAMGFFTSAYDLFIIGTALVLIKDEWHLSAQQVGLIGSISLIATFFGAFIFG
NLADRLGRKSVYGIEAILMVLGALMSAFSFNVGFLLLSRFILGLGVGGDYPLSAVIMSEYANTTTRGRMVTLVFSAQALG
LIAGPMVALTLLAAGVDKDLAWRIMLGLGALPAATVIYLRRRLPESPRWLARVKGEKEVAAKDLASFSLGDIVIEEVKDQ
IVKKPLSKYWLQLLGTAGTWFLFDYAYYGNTISTPLVLKHIATHANLIQSTAISFLIFVVFAVPGYFIAAATIDKIGHKF
LQMLGFFMMGLMFFIIGMFPSIVHNFPLFVTLYGLSYFFAEFGPNTTTFVLPAEVFPVNVRTTAHGISAGVAKIGAFIGA
YFFPILLKSLGLSHTLLLTFVFSLAGLILTYIAIPEPKGKSLEEVSQEDTTLSKPSPAT

Sequences:

>Translated_459_residues
MAKVVKGSIAEALNTSQFSLFHIKAMFASAMGFFTSAYDLFIIGTALVLIKDEWHLSAQQVGLIGSISLIATFFGAFIFG
NLADRLGRKSVYGIEAILMVLGALMSAFSFNVGFLLLSRFILGLGVGGDYPLSAVIMSEYANTTTRGRMVTLVFSAQALG
LIAGPMVALTLLAAGVDKDLAWRIMLGLGALPAATVIYLRRRLPESPRWLARVKGEKEVAAKDLASFSLGDIVIEEVKDQ
IVKKPLSKYWLQLLGTAGTWFLFDYAYYGNTISTPLVLKHIATHANLIQSTAISFLIFVVFAVPGYFIAAATIDKIGHKF
LQMLGFFMMGLMFFIIGMFPSIVHNFPLFVTLYGLSYFFAEFGPNTTTFVLPAEVFPVNVRTTAHGISAGVAKIGAFIGA
YFFPILLKSLGLSHTLLLTFVFSLAGLILTYIAIPEPKGKSLEEVSQEDTTLSKPSPAT
>Mature_458_residues
AKVVKGSIAEALNTSQFSLFHIKAMFASAMGFFTSAYDLFIIGTALVLIKDEWHLSAQQVGLIGSISLIATFFGAFIFGN
LADRLGRKSVYGIEAILMVLGALMSAFSFNVGFLLLSRFILGLGVGGDYPLSAVIMSEYANTTTRGRMVTLVFSAQALGL
IAGPMVALTLLAAGVDKDLAWRIMLGLGALPAATVIYLRRRLPESPRWLARVKGEKEVAAKDLASFSLGDIVIEEVKDQI
VKKPLSKYWLQLLGTAGTWFLFDYAYYGNTISTPLVLKHIATHANLIQSTAISFLIFVVFAVPGYFIAAATIDKIGHKFL
QMLGFFMMGLMFFIIGMFPSIVHNFPLFVTLYGLSYFFAEFGPNTTTFVLPAEVFPVNVRTTAHGISAGVAKIGAFIGAY
FFPILLKSLGLSHTLLLTFVFSLAGLILTYIAIPEPKGKSLEEVSQEDTTLSKPSPAT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=472, Percent_Identity=23.728813559322, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI68226420, Length=472, Percent_Identity=25, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI190684655, Length=472, Percent_Identity=25, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI68226418, Length=472, Percent_Identity=25, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI47933389, Length=511, Percent_Identity=22.3091976516634, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI47933387, Length=428, Percent_Identity=23.5981308411215, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI213021148, Length=472, Percent_Identity=22.4576271186441, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI166064021, Length=422, Percent_Identity=23.696682464455, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI4507005, Length=382, Percent_Identity=23.5602094240838, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4506999, Length=419, Percent_Identity=25.0596658711217, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI203098995, Length=220, Percent_Identity=31.8181818181818, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI7662270, Length=293, Percent_Identity=24.2320819112628, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4557851, Length=429, Percent_Identity=27.7389277389277, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI24497490, Length=372, Percent_Identity=21.2365591397849, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI216548223, Length=284, Percent_Identity=23.943661971831, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI23510410, Length=304, Percent_Identity=27.6315789473684, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI8923870, Length=444, Percent_Identity=23.8738738738739, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI262399383, Length=257, Percent_Identity=24.5136186770428, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1786229, Length=433, Percent_Identity=25.8660508083141, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87082159, Length=426, Percent_Identity=23.4741784037559, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1789207, Length=445, Percent_Identity=26.0674157303371, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790463, Length=431, Percent_Identity=24.5939675174014, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789312, Length=441, Percent_Identity=25.6235827664399, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082404, Length=199, Percent_Identity=26.6331658291457, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788074, Length=407, Percent_Identity=24.5700245700246, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87082231, Length=208, Percent_Identity=24.5192307692308, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788942, Length=365, Percent_Identity=26.3013698630137, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=426, Percent_Identity=22.3004694835681, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323512, Length=508, Percent_Identity=33.0708661417323, Blast_Score=243, Evalue=6e-65,
Organism=Saccharomyces cerevisiae, GI6319941, Length=435, Percent_Identity=25.7471264367816, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324011, Length=464, Percent_Identity=24.3534482758621, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320766, Length=444, Percent_Identity=26.5765765765766, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324400, Length=444, Percent_Identity=25.9009009009009, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319956, Length=444, Percent_Identity=25.4504504504505, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323653, Length=449, Percent_Identity=24.2761692650334, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6320595, Length=176, Percent_Identity=29.5454545454545, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322618, Length=444, Percent_Identity=25.4504504504505, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323110, Length=439, Percent_Identity=23.0068337129841, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324469, Length=482, Percent_Identity=23.2365145228216, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320745, Length=424, Percent_Identity=22.6415094339623, Blast_Score=66, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6324417, Length=445, Percent_Identity=24.0449438202247, Blast_Score=66, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320705, Length=490, Percent_Identity=23.469387755102, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322242, Length=445, Percent_Identity=23.8202247191011, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319718, Length=187, Percent_Identity=30.4812834224599, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI161080349, Length=393, Percent_Identity=25.6997455470738, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24654932, Length=393, Percent_Identity=25.6997455470738, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17737517, Length=393, Percent_Identity=25.6997455470738, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI161080351, Length=399, Percent_Identity=25.5639097744361, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161080353, Length=393, Percent_Identity=25.6997455470738, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19922874, Length=427, Percent_Identity=21.3114754098361, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17737451, Length=419, Percent_Identity=25.2983293556086, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24652312, Length=419, Percent_Identity=25.2983293556086, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19920644, Length=411, Percent_Identity=23.6009732360097, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI19922616, Length=434, Percent_Identity=23.7327188940092, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640198, Length=201, Percent_Identity=27.363184079602, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640196, Length=201, Percent_Identity=27.363184079602, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640200, Length=201, Percent_Identity=27.363184079602, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24668456, Length=427, Percent_Identity=22.0140515222482, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24649618, Length=379, Percent_Identity=22.6912928759894, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI62484254, Length=446, Percent_Identity=21.9730941704036, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 49797; Mature: 49665

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVVKGSIAEALNTSQFSLFHIKAMFASAMGFFTSAYDLFIIGTALVLIKDEWHLSAQQ
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHH
VGLIGSISLIATFFGAFIFGNLADRLGRKSVYGIEAILMVLGALMSAFSFNVGFLLLSRF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ILGLGVGGDYPLSAVIMSEYANTTTRGRMVTLVFSAQALGLIAGPMVALTLLAAGVDKDL
HHHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHH
AWRIMLGLGALPAATVIYLRRRLPESPRWLARVKGEKEVAAKDLASFSLGDIVIEEVKDQ
HHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IVKKPLSKYWLQLLGTAGTWFLFDYAYYGNTISTPLVLKHIATHANLIQSTAISFLIFVV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAVPGYFIAAATIDKIGHKFLQMLGFFMMGLMFFIIGMFPSIVHNFPLFVTLYGLSYFFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EFGPNTTTFVLPAEVFPVNVRTTAHGISAGVAKIGAFIGAYFFPILLKSLGLSHTLLLTF
HHCCCCEEEEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VFSLAGLILTYIAIPEPKGKSLEEVSQEDTTLSKPSPAT
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AKVVKGSIAEALNTSQFSLFHIKAMFASAMGFFTSAYDLFIIGTALVLIKDEWHLSAQQ
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHH
VGLIGSISLIATFFGAFIFGNLADRLGRKSVYGIEAILMVLGALMSAFSFNVGFLLLSRF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ILGLGVGGDYPLSAVIMSEYANTTTRGRMVTLVFSAQALGLIAGPMVALTLLAAGVDKDL
HHHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHH
AWRIMLGLGALPAATVIYLRRRLPESPRWLARVKGEKEVAAKDLASFSLGDIVIEEVKDQ
HHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IVKKPLSKYWLQLLGTAGTWFLFDYAYYGNTISTPLVLKHIATHANLIQSTAISFLIFVV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAVPGYFIAAATIDKIGHKFLQMLGFFMMGLMFFIIGMFPSIVHNFPLFVTLYGLSYFFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EFGPNTTTFVLPAEVFPVNVRTTAHGISAGVAKIGAFIGAYFFPILLKSLGLSHTLLLTF
HHCCCCEEEEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VFSLAGLILTYIAIPEPKGKSLEEVSQEDTTLSKPSPAT
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503 [H]