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The map label for this gene is nusG [H]

Identifier: 195952631

GI number: 195952631

Start: 224187

End: 224924

Strand: Direct

Name: nusG [H]

Synonym: HY04AAS1_0253

Alternate gene names: 195952631

Gene position: 224187-224924 (Clockwise)

Preceding gene: 195952630

Following gene: 195952632

Centisome position: 14.38

GC content: 36.86

Gene sequence:

>738_bases
ATGACTGATATGAAGTGGTATGCTCTGCAGGTTGAAGCCGGAAAGGAGACCACCGCTAAAGAATCTCTTATGAAGGTTAT
AGAACTTGACAAGATAAACGATCTGGTAGAAGATATAGTGTTGCCTGCAGAGGAAAAAGTAGTTATAAAAGCCCTAGGGA
AAGAAAAATATAGATTATCTTTAAGAGGAAACAACAGGGATATAAGTGTTTTGGGTAAAAAATGCGTAACTGTATTTAGA
ATAGAAGAAGGCACTGTAAAGGTTGTGCCATCGGAAGATGATGAAGACTGTAACCATGACTGTATAAGGGCTGGAGAAAT
ATCTAAACCGGGGCAAAAAATTACTTGCAAGGACAATAAAACTGAAGCAAAAATAGTTTTGGATAATAAAATGTTTCCAG
GGTATATATTGTTAAAAGCTCATATGGACGACAGGCTTTTAAGAGCAATAGAAAAGGCACCGCACGTTTACAAGCCGGTC
TTGGTGGGTGGCAAAATAGCCCCTTTGAAAGAGGAAGAAGTAAATAAAATATTGGCACATGCTCAGAGAGGATTCAAAAC
CAAAAAAGCGGTATTTGAAAAAGGTGAGCAGGTTAGAATTATAGAAGGTCCTTTTATGAGTTTTACCGGTACTATAGAAG
AAGTGAACTTAGAAAGAGAAAAGTTAAATGTGCTTATTAGCATATTTGGAAGGTTAACACCTGTGGAGCTTGATTTTTCA
CAGGTAGAAAAGATATAA

Upstream 100 bases:

>100_bases
TTATAATATTTTCCTTATTTTTTGGAATTTATTTATGGATTGTAGATTTGAGTTTTACGAAGATTTTGTCGTTTATATTT
GGTATTTGGGGTGGTAGTTT

Downstream 100 bases:

>100_bases
GGAGTAGCATATGGCTAAAAAGTTAACAGCTACAGTTGAATTGATGCTTCCAGCGGGGCAAGCGACACCGGCTCCTCCTG
TTGGGCCTGCTTTAGGTCAG

Product: NusG antitermination factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MTDMKWYALQVEAGKETTAKESLMKVIELDKINDLVEDIVLPAEEKVVIKALGKEKYRLSLRGNNRDISVLGKKCVTVFR
IEEGTVKVVPSEDDEDCNHDCIRAGEISKPGQKITCKDNKTEAKIVLDNKMFPGYILLKAHMDDRLLRAIEKAPHVYKPV
LVGGKIAPLKEEEVNKILAHAQRGFKTKKAVFEKGEQVRIIEGPFMSFTGTIEEVNLEREKLNVLISIFGRLTPVELDFS
QVEKI

Sequences:

>Translated_245_residues
MTDMKWYALQVEAGKETTAKESLMKVIELDKINDLVEDIVLPAEEKVVIKALGKEKYRLSLRGNNRDISVLGKKCVTVFR
IEEGTVKVVPSEDDEDCNHDCIRAGEISKPGQKITCKDNKTEAKIVLDNKMFPGYILLKAHMDDRLLRAIEKAPHVYKPV
LVGGKIAPLKEEEVNKILAHAQRGFKTKKAVFEKGEQVRIIEGPFMSFTGTIEEVNLEREKLNVLISIFGRLTPVELDFS
QVEKI
>Mature_244_residues
TDMKWYALQVEAGKETTAKESLMKVIELDKINDLVEDIVLPAEEKVVIKALGKEKYRLSLRGNNRDISVLGKKCVTVFRI
EEGTVKVVPSEDDEDCNHDCIRAGEISKPGQKITCKDNKTEAKIVLDNKMFPGYILLKAHMDDRLLRAIEKAPHVYKPVL
VGGKIAPLKEEEVNKILAHAQRGFKTKKAVFEKGEQVRIIEGPFMSFTGTIEEVNLEREKLNVLISIFGRLTPVELDFSQ
VEKI

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase [H]

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain [H]

Homologues:

Organism=Escherichia coli, GI1790414, Length=122, Percent_Identity=45.0819672131148, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF00467 KOW; PF02357 NusG [H]

EC number: NA

Molecular weight: Translated: 27678; Mature: 27546

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDMKWYALQVEAGKETTAKESLMKVIELDKINDLVEDIVLPAEEKVVIKALGKEKYRLS
CCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEE
LRGNNRDISVLGKKCVTVFRIEEGTVKVVPSEDDEDCNHDCIRAGEISKPGQKITCKDNK
ECCCCCCHHHHHCCEEEEEEECCCEEEEECCCCCCCCCCHHEECCCCCCCCCEEEECCCC
TEAKIVLDNKMFPGYILLKAHMDDRLLRAIEKAPHVYKPVLVGGKIAPLKEEEVNKILAH
CEEEEEEECCCCCCEEEEEECCCHHHHHHHHHCCCHHCCEEECCEECCCCHHHHHHHHHH
AQRGFKTKKAVFEKGEQVRIIEGPFMSFTGTIEEVNLEREKLNVLISIFGRLTPVELDFS
HHHCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCEEECHH
QVEKI
HHHCC
>Mature Secondary Structure 
TDMKWYALQVEAGKETTAKESLMKVIELDKINDLVEDIVLPAEEKVVIKALGKEKYRLS
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEE
LRGNNRDISVLGKKCVTVFRIEEGTVKVVPSEDDEDCNHDCIRAGEISKPGQKITCKDNK
ECCCCCCHHHHHCCEEEEEEECCCEEEEECCCCCCCCCCHHEECCCCCCCCCEEEECCCC
TEAKIVLDNKMFPGYILLKAHMDDRLLRAIEKAPHVYKPVLVGGKIAPLKEEEVNKILAH
CEEEEEEECCCCCCEEEEEECCCHHHHHHHHHCCCHHCCEEECCEECCCCHHHHHHHHHH
AQRGFKTKKAVFEKGEQVRIIEGPFMSFTGTIEEVNLEREKLNVLISIFGRLTPVELDFS
HHHCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCEEECHH
QVEKI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320; 12198166 [H]