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The map label for this gene is dsdC [H]

Identifier: 194738266

GI number: 194738266

Start: 3883740

End: 3884678

Strand: Reverse

Name: dsdC [H]

Synonym: SeSA_A4009

Alternate gene names: 194738266

Gene position: 3884678-3883740 (Counterclockwise)

Preceding gene: 194734143

Following gene: 194738160

Centisome position: 82.49

GC content: 53.14

Gene sequence:

>939_bases
ATGACTGAGGTTGCCATGGAACCCCTTCGCGATACCCGAAACCGCTTACTCAACGGCTGGCAGTTATCCAAACTCTATAC
TTTTGAAGTCGCGGCCAGACACCAGTCCTTTGCTCTGGCGGCAGATGAGCTGTCGTTAAGCCCAAGTGCGGTAAGCCATC
GTATCAATCAACTGGAAGCCGAGTTGGGAATCCAGCTATTTGTCTGCTCTCACCGTAAAGTGGAGCTTACCCATGAAGGC
AAACGGGTATTCTGGGCGCTGAAATCGTCGCTGGATACGTTGAATCAGGAAATCCTCGATATCAAAAATCAGGAACTGTC
CGGCACGTTGACCGTGTATTCCCGTCCCTCTATCGCCCAGTGCTGGCTGGTGCCCGCGCTGGGGGACTTTACCCGTCGCT
ATCCGTCAATTTCTCTCACTATGCTGACCGGCAACGATAACGTTAACCTACAGCGTGCCGGCATTGACCTGGCTATCTAT
TTTGACGATGCGCCGTCGGCGCAGCTCACGCACCATTTTTTAATGGATGAGGCGATTTTGCCCGTTTGCAGCCCGGATTA
CGCCCGACGTTTCGCCTTGCAGGACAACCTGAATAACCTGCGGCACTGTACGCTCTTACACGACAGACAAGCGTGGAGTA
ACGATTCGGGCATCGATGAGTGGCACAGTTGGGCGCAGCATTTTGCAGTAAATTTGCCGGATTCATCCGGCATTGGCTTC
GATCGTTCTGATTTAGCGGTGATTGCCGCGATGAACCACATTGGCGTGGCGATGGGGCGTAAACGGCTGGTGCAAAAGCG
TCTCGACAGCGGCGAACTGATTGCGCCTTTTGGTGACATGAGGCTGAAATGTCATCAGCATTATTATGTCACCACTCTGC
CTGGCAGGCAGTGGCCGAAAATCGAGGCATTTATTCGCTGGTTGCAGGAACAGGTGTGA

Upstream 100 bases:

>100_bases
TTCCATCTAATATTGCCTTTATTTTGCGATATGGTTCATTTTGCTTCATCTATGTGCGGATTTTTTCAGCGTGTTTTTTT
ACACTTCGGGAAATTAAAAG

Downstream 100 bases:

>100_bases
AGATTTATTACGCTTTGCCGCTACACCTGCCGGGAGTGAATATGCTAAATACGTGCTATCACCGTGGTAAAAATTTTAGG
GGGCGTCGTGTTTAAACCGC

Product: DNA-binding transcriptional regulator DsdC

Products: NA

Alternate protein names: D-serine deaminase activator [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTEVAMEPLRDTRNRLLNGWQLSKLYTFEVAARHQSFALAADELSLSPSAVSHRINQLEAELGIQLFVCSHRKVELTHEG
KRVFWALKSSLDTLNQEILDIKNQELSGTLTVYSRPSIAQCWLVPALGDFTRRYPSISLTMLTGNDNVNLQRAGIDLAIY
FDDAPSAQLTHHFLMDEAILPVCSPDYARRFALQDNLNNLRHCTLLHDRQAWSNDSGIDEWHSWAQHFAVNLPDSSGIGF
DRSDLAVIAAMNHIGVAMGRKRLVQKRLDSGELIAPFGDMRLKCHQHYYVTTLPGRQWPKIEAFIRWLQEQV

Sequences:

>Translated_312_residues
MTEVAMEPLRDTRNRLLNGWQLSKLYTFEVAARHQSFALAADELSLSPSAVSHRINQLEAELGIQLFVCSHRKVELTHEG
KRVFWALKSSLDTLNQEILDIKNQELSGTLTVYSRPSIAQCWLVPALGDFTRRYPSISLTMLTGNDNVNLQRAGIDLAIY
FDDAPSAQLTHHFLMDEAILPVCSPDYARRFALQDNLNNLRHCTLLHDRQAWSNDSGIDEWHSWAQHFAVNLPDSSGIGF
DRSDLAVIAAMNHIGVAMGRKRLVQKRLDSGELIAPFGDMRLKCHQHYYVTTLPGRQWPKIEAFIRWLQEQV
>Mature_311_residues
TEVAMEPLRDTRNRLLNGWQLSKLYTFEVAARHQSFALAADELSLSPSAVSHRINQLEAELGIQLFVCSHRKVELTHEGK
RVFWALKSSLDTLNQEILDIKNQELSGTLTVYSRPSIAQCWLVPALGDFTRRYPSISLTMLTGNDNVNLQRAGIDLAIYF
DDAPSAQLTHHFLMDEAILPVCSPDYARRFALQDNLNNLRHCTLLHDRQAWSNDSGIDEWHSWAQHFAVNLPDSSGIGFD
RSDLAVIAAMNHIGVAMGRKRLVQKRLDSGELIAPFGDMRLKCHQHYYVTTLPGRQWPKIEAFIRWLQEQV

Specific function: Regulates the expression of the dsd operon for D-serine deaminase (dsdA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788706, Length=307, Percent_Identity=90.228013029316, Blast_Score=582, Evalue=1e-168,
Organism=Escherichia coli, GI1786448, Length=296, Percent_Identity=32.0945945945946, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1789173, Length=288, Percent_Identity=30.9027777777778, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=25.3378378378378, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787128, Length=285, Percent_Identity=28.4210526315789, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI145693193, Length=177, Percent_Identity=30.5084745762712, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI145693105, Length=172, Percent_Identity=26.1627906976744, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788748, Length=181, Percent_Identity=28.1767955801105, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789440, Length=268, Percent_Identity=24.6268656716418, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87081978, Length=193, Percent_Identity=29.0155440414508, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011781
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35519; Mature: 35388

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVAMEPLRDTRNRLLNGWQLSKLYTFEVAARHQSFALAADELSLSPSAVSHRINQLEA
CCCHHHHHHHHHHHHHCCCEEEEEEEEEEEHHCCCCEEEEHHHCCCCHHHHHHHHHHHHH
ELGIQLFVCSHRKVELTHEGKRVFWALKSSLDTLNQEILDIKNQELSGTLTVYSRPSIAQ
HCCEEEEEECCCEEEEEECCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHH
CWLVPALGDFTRRYPSISLTMLTGNDNVNLQRAGIDLAIYFDDAPSAQLTHHFLMDEAIL
EEEEHHHHHHHHHCCCEEEEEEECCCCCEEEECCEEEEEEECCCCCHHHHHHHHHHHHCC
PVCSPDYARRFALQDNLNNLRHCTLLHDRQAWSNDSGIDEWHSWAQHFAVNLPDSSGIGF
CCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCC
DRSDLAVIAAMNHIGVAMGRKRLVQKRLDSGELIAPFGDMRLKCHQHYYVTTLPGRQWPK
CCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECEEEEEECCCCCCCH
IEAFIRWLQEQV
HHHHHHHHHHCC
>Mature Secondary Structure 
TEVAMEPLRDTRNRLLNGWQLSKLYTFEVAARHQSFALAADELSLSPSAVSHRINQLEA
CCHHHHHHHHHHHHHCCCEEEEEEEEEEEHHCCCCEEEEHHHCCCCHHHHHHHHHHHHH
ELGIQLFVCSHRKVELTHEGKRVFWALKSSLDTLNQEILDIKNQELSGTLTVYSRPSIAQ
HCCEEEEEECCCEEEEEECCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHH
CWLVPALGDFTRRYPSISLTMLTGNDNVNLQRAGIDLAIYFDDAPSAQLTHHFLMDEAIL
EEEEHHHHHHHHHCCCEEEEEEECCCCCEEEECCEEEEEEECCCCCHHHHHHHHHHHHCC
PVCSPDYARRFALQDNLNNLRHCTLLHDRQAWSNDSGIDEWHSWAQHFAVNLPDSSGIGF
CCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCC
DRSDLAVIAAMNHIGVAMGRKRLVQKRLDSGELIAPFGDMRLKCHQHYYVTTLPGRQWPK
CCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECEEEEEECCCCCCCH
IEAFIRWLQEQV
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592420; 9205837; 9278503 [H]