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The map label for this gene is yfcG [H]

Identifier: 194738260

GI number: 194738260

Start: 2463512

End: 2464159

Strand: Direct

Name: yfcG [H]

Synonym: SeSA_A2578

Alternate gene names: 194738260

Gene position: 2463512-2464159 (Clockwise)

Preceding gene: 194737232

Following gene: 194736673

Centisome position: 52.31

GC content: 52.93

Gene sequence:

>648_bases
ATGATTGACCTTTACTACGCCCCCACGCCCAACGGGCATAAAATAACGCTGTTTCTGGAAGAGGCGGAGCTGGCGTATCG
TTTGCTAAAAGTAGATATCAGCAAGGGCAATCAGTTTCGCCCTGATTTTTTGGCTATCTCTCCCAATAATAAAATTCCTG
CCATCGTCGATCACGCCCCGGCAGACGGCGGTCAACCGCTTAGTCTTTTTGAATCCGGTGAAATTCTTCTCTACCTGGCG
GAAAAAAGCGGCAAACTGCTTAGCGGGGAGCTGCGTGAACGCCATACCACACTGCAATGGCTGTTCTGGCAGGTCGGCGG
GTTAGGGCCGATGCTGGGCCAGAATCATCACTTTAACCATTTTGCGCCGCAGGCCATCCCCTATGCGATTGAACGCTATC
AGGTTGAAACGCAACGCTTATACAACGTCCTGAATAAACGCCTGGAAACCTCCCCGTGGCTGGGCGGCGACCACTACAGT
ATTGCGGATATCGCCAGTTGGCCGTGGGTTAACGCACATCAGCGTCAGCGAATCGATCTTGATACCTACCCGGCGGTGTA
TAACTGGTTTGAACGCATTCGCACGCGTCCTGCGACAGCGCGCGCACTGTTACAAGCGCAACTGCACTGTAACAGTACGA
AAGCGTAA

Upstream 100 bases:

>100_bases
GCGTCTTTCGCCTGCTGTCACCTGATGAAAACTCACACACATCAGGAGGCTTTCTATACTTAATTCAGCCCAGACTCTTT
ACGCACATGCAGGAGCCAAA

Downstream 100 bases:

>100_bases
CGCGGTAGCATACATCATGTATGATGTAGAGGTGTATACACGGAAAAAACCTGCGTCCGGCACCCTTATTCGTATTAAAA
ACCTGACATTAGGGAAGAGG

Product: glutathione S-transferase, N- domain

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MIDLYYAPTPNGHKITLFLEEAELAYRLLKVDISKGNQFRPDFLAISPNNKIPAIVDHAPADGGQPLSLFESGEILLYLA
EKSGKLLSGELRERHTTLQWLFWQVGGLGPMLGQNHHFNHFAPQAIPYAIERYQVETQRLYNVLNKRLETSPWLGGDHYS
IADIASWPWVNAHQRQRIDLDTYPAVYNWFERIRTRPATARALLQAQLHCNSTKA

Sequences:

>Translated_215_residues
MIDLYYAPTPNGHKITLFLEEAELAYRLLKVDISKGNQFRPDFLAISPNNKIPAIVDHAPADGGQPLSLFESGEILLYLA
EKSGKLLSGELRERHTTLQWLFWQVGGLGPMLGQNHHFNHFAPQAIPYAIERYQVETQRLYNVLNKRLETSPWLGGDHYS
IADIASWPWVNAHQRQRIDLDTYPAVYNWFERIRTRPATARALLQAQLHCNSTKA
>Mature_215_residues
MIDLYYAPTPNGHKITLFLEEAELAYRLLKVDISKGNQFRPDFLAISPNNKIPAIVDHAPADGGQPLSLFESGEILLYLA
EKSGKLLSGELRERHTTLQWLFWQVGGLGPMLGQNHHFNHFAPQAIPYAIERYQVETQRLYNVLNKRLETSPWLGGDHYS
IADIASWPWVNAHQRQRIDLDTYPAVYNWFERIRTRPATARALLQAQLHCNSTKA

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=208, Percent_Identity=83.1730769230769, Blast_Score=359, Evalue=1e-101,
Organism=Escherichia coli, GI87082195, Length=217, Percent_Identity=39.63133640553, Blast_Score=151, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6324100, Length=233, Percent_Identity=33.9055793991416, Blast_Score=125, Evalue=4e-30,
Organism=Drosophila melanogaster, GI28571670, Length=167, Percent_Identity=28.7425149700599, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17864592, Length=199, Percent_Identity=26.6331658291457, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI85725204, Length=201, Percent_Identity=27.8606965174129, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17737923, Length=201, Percent_Identity=27.8606965174129, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45549270, Length=199, Percent_Identity=26.1306532663317, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17864598, Length=207, Percent_Identity=28.5024154589372, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17864594, Length=195, Percent_Identity=26.1538461538462, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646249, Length=199, Percent_Identity=27.1356783919598, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 24603; Mature: 24603

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLYYAPTPNGHKITLFLEEAELAYRLLKVDISKGNQFRPDFLAISPNNKIPAIVDHAP
CEEEEECCCCCCCEEEEEEECHHHHHHHHEEECCCCCCCCCCEEEECCCCCCCEEEECCC
ADGGQPLSLFESGEILLYLAEKSGKLLSGELRERHTTLQWLFWQVGGLGPMLGQNHHFNH
CCCCCCEEEECCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
FAPQAIPYAIERYQVETQRLYNVLNKRLETSPWLGGDHYSIADIASWPWVNAHQRQRIDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCC
DTYPAVYNWFERIRTRPATARALLQAQLHCNSTKA
CCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIDLYYAPTPNGHKITLFLEEAELAYRLLKVDISKGNQFRPDFLAISPNNKIPAIVDHAP
CEEEEECCCCCCCEEEEEEECHHHHHHHHEEECCCCCCCCCCEEEECCCCCCCEEEECCC
ADGGQPLSLFESGEILLYLAEKSGKLLSGELRERHTTLQWLFWQVGGLGPMLGQNHHFNH
CCCCCCEEEECCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
FAPQAIPYAIERYQVETQRLYNVLNKRLETSPWLGGDHYSIADIASWPWVNAHQRQRIDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCC
DTYPAVYNWFERIRTRPATARALLQAQLHCNSTKA
CCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]