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The map label for this gene is wecF [H]

Identifier: 194738194

GI number: 194738194

Start: 4015359

End: 4016438

Strand: Direct

Name: wecF [H]

Synonym: SeSA_A4138

Alternate gene names: 194738194

Gene position: 4015359-4016438 (Clockwise)

Preceding gene: 194734150

Following gene: 194735075

Centisome position: 85.27

GC content: 54.54

Gene sequence:

>1080_bases
ATGACTGTACTGATTCACGTCCTGGGATCGGATATCCCTCACCATAACCACACCGTGTTGCGGTTTTTCAATGATACGCT
GGCCGCCACAAGCGAGCACGCGCGTGAATTTATGGTTGCTGGCGAAGATAACGGCTTCACGGAAAGCTGCCCGGCGCTCT
CGCTTCGTTTTTATGGCAGTAAGAAAGCGCTGGCGCAGGCGGTCATCGCCAAAGCGAAAGCAAATCGTCGGCAGAGATTC
TTCTTTCACGGTCAGTTCAACACCAGCCTGTGGCTGGCGCTGTTAAGCGGCGGTATTAAGCCAGCTCAGTTTTACTGGCA
TATCTGGGGCGCGGATCTCTACGAAGTGTCCCACGGGCTGAAATTCCGCCTTTTCTACCCGCTTCGTCGTATCGCGCAGG
GACGAGTAGGGGGCGTATTCGCGACGCGCGGCGATCTCAGCTATTTTGCGCGCCAGCACCCGGGCGTACGCGGCGAGTTG
CTCTATTTCCCGACGCGCATGGATCCTTCCCTGAACTCTATGGCAAAAGAGCGCCAACGTGCGGGAAAATTGACCATTTT
GGTAGGGAACTCCGGCGATCGCAGTAACGAGCATATTACGGCGTTACGGGCGGTGTATCAGCAGTTTGGCGATACGGTAA
ACGTGGTGGTGCCGATGGGCTATCCGGCCAATAACCAGGCCTATATTGATGAGGTTCGTCAGGTCGGTCTGGCGCTATTT
AGCGCCGAAAATCTACAAATTCTTAGCGAAAAAATGGAATTTGATGCCTATCTTGCGCTGTTGCGCCAGTGCGACCTCGG
TTATTTTATTTTTGCCCGCCAACAGGGGATCGGGACGTTGTGCCTGCTAATTCAGGCCGATATCCCGTGCGTGTTGAATC
GCGACAATCCTTTCTGGCAGGATATGGCGGAACAGCATCTGCCCGTTCTGTTTACCACGGACGATCTTAATGAGCAGGTC
GTGCGCGAGGCGCAGCGTCAGCTCGCATCGGTAGATAAAAGCGGCATCACCTTCTTTAGCCCCAACTACCTGCAACCGTG
GCATAATGCGTTGAGAATCGCCGCAGGAGAAGCCGAATGA

Upstream 100 bases:

>100_bases
CCGCTCACGGCGCGCTGGGTGCGGCACAGGCTTATATGGCCACCTATATTGTCTATTTTTCACTTTGTTGCGGCGTATTT
TTACTCTGGCGTAGGCGAGC

Downstream 100 bases:

>100_bases
GTTTAATGCAATTCAGCGGGCTGCTGGTGGTCTGGCTGCTCTCTACGCTGTTTATCGCCACGCTGACCTGGTTTGAATTT
CGCCGCGTGCGTTTTAACTT

Product: 4-alpha-L-fucosyltransferase

Products: NA

Alternate protein names: TDP-Fuc4NAc:lipid II Fuc4NAc transferase; Fuc4NAc transferase [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MTVLIHVLGSDIPHHNHTVLRFFNDTLAATSEHAREFMVAGEDNGFTESCPALSLRFYGSKKALAQAVIAKAKANRRQRF
FFHGQFNTSLWLALLSGGIKPAQFYWHIWGADLYEVSHGLKFRLFYPLRRIAQGRVGGVFATRGDLSYFARQHPGVRGEL
LYFPTRMDPSLNSMAKERQRAGKLTILVGNSGDRSNEHITALRAVYQQFGDTVNVVVPMGYPANNQAYIDEVRQVGLALF
SAENLQILSEKMEFDAYLALLRQCDLGYFIFARQQGIGTLCLLIQADIPCVLNRDNPFWQDMAEQHLPVLFTTDDLNEQV
VREAQRQLASVDKSGITFFSPNYLQPWHNALRIAAGEAE

Sequences:

>Translated_359_residues
MTVLIHVLGSDIPHHNHTVLRFFNDTLAATSEHAREFMVAGEDNGFTESCPALSLRFYGSKKALAQAVIAKAKANRRQRF
FFHGQFNTSLWLALLSGGIKPAQFYWHIWGADLYEVSHGLKFRLFYPLRRIAQGRVGGVFATRGDLSYFARQHPGVRGEL
LYFPTRMDPSLNSMAKERQRAGKLTILVGNSGDRSNEHITALRAVYQQFGDTVNVVVPMGYPANNQAYIDEVRQVGLALF
SAENLQILSEKMEFDAYLALLRQCDLGYFIFARQQGIGTLCLLIQADIPCVLNRDNPFWQDMAEQHLPVLFTTDDLNEQV
VREAQRQLASVDKSGITFFSPNYLQPWHNALRIAAGEAE
>Mature_358_residues
TVLIHVLGSDIPHHNHTVLRFFNDTLAATSEHAREFMVAGEDNGFTESCPALSLRFYGSKKALAQAVIAKAKANRRQRFF
FHGQFNTSLWLALLSGGIKPAQFYWHIWGADLYEVSHGLKFRLFYPLRRIAQGRVGGVFATRGDLSYFARQHPGVRGELL
YFPTRMDPSLNSMAKERQRAGKLTILVGNSGDRSNEHITALRAVYQQFGDTVNVVVPMGYPANNQAYIDEVRQVGLALFS
AENLQILSEKMEFDAYLALLRQCDLGYFIFARQQGIGTLCLLIQADIPCVLNRDNPFWQDMAEQHLPVLFTTDDLNEQVV
REAQRQLASVDKSGITFFSPNYLQPWHNALRIAAGEAE

Specific function: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 56 family [H]

Homologues:

Organism=Escherichia coli, GI48994971, Length=357, Percent_Identity=82.9131652661064, Blast_Score=632, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009993 [H]

Pfam domain/function: PF07429 Fuc4NAc_transf [H]

EC number: NA

Molecular weight: Translated: 40517; Mature: 40386

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLIHVLGSDIPHHNHTVLRFFNDTLAATSEHAREFMVAGEDNGFTESCPALSLRFYGS
CEEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEEECC
KKALAQAVIAKAKANRRQRFFFHGQFNTSLWLALLSGGIKPAQFYWHIWGADLYEVSHGL
HHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCC
KFRLFYPLRRIAQGRVGGVFATRGDLSYFARQHPGVRGELLYFPTRMDPSLNSMAKERQR
EEEEEHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHH
AGKLTILVGNSGDRSNEHITALRAVYQQFGDTVNVVVPMGYPANNQAYIDEVRQVGLALF
CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHH
SAENLQILSEKMEFDAYLALLRQCDLGYFIFARQQGIGTLCLLIQADIPCVLNRDNPFWQ
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCEEECCCCCHHH
DMAEQHLPVLFTTDDLNEQVVREAQRQLASVDKSGITFFSPNYLQPWHNALRIAAGEAE
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHEEECCCCC
>Mature Secondary Structure 
TVLIHVLGSDIPHHNHTVLRFFNDTLAATSEHAREFMVAGEDNGFTESCPALSLRFYGS
EEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEEECC
KKALAQAVIAKAKANRRQRFFFHGQFNTSLWLALLSGGIKPAQFYWHIWGADLYEVSHGL
HHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCC
KFRLFYPLRRIAQGRVGGVFATRGDLSYFARQHPGVRGELLYFPTRMDPSLNSMAKERQR
EEEEEHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHH
AGKLTILVGNSGDRSNEHITALRAVYQQFGDTVNVVVPMGYPANNQAYIDEVRQVGLALF
CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHH
SAENLQILSEKMEFDAYLALLRQCDLGYFIFARQQGIGTLCLLIQADIPCVLNRDNPFWQ
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCEEECCCCCHHH
DMAEQHLPVLFTTDDLNEQVVREAQRQLASVDKSGITFFSPNYLQPWHNALRIAAGEAE
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA