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The map label for this gene is ynfE [H]

Identifier: 194738045

GI number: 194738045

Start: 1544414

End: 1546852

Strand: Reverse

Name: ynfE [H]

Synonym: SeSA_A1601

Alternate gene names: 194738045

Gene position: 1546852-1544414 (Counterclockwise)

Preceding gene: 194734287

Following gene: 194737575

Centisome position: 32.85

GC content: 54.33

Gene sequence:

>2439_bases
ATGCCCGGAGAAAAGCAACAAACAGGCGTTAGCCGCAGGACGTTAGTGAAATCAGCGGCGCTTGGCTCACTGGCGCTGGC
TGCCGGAGGCGTATCTTTACCGTTTGGGATGCGTACCGCGGCCGCGGCGGTGCAGCAGGCCATGCGCAACGAAGAAGATA
AAATCGTCTGGGGCGCCTGTTCGGTCAACTGCGGCAGTCGCTGCGCCCTGCGTCTGCATGTAAAAGATAATGAAGTCTGG
TGGGTTGAAACTGATAATACTGGCGACGATGTCTACGGCAATCATCAGGTTCGCGCCTGTCTGCGGGGCCGTTCAATCCG
TCGGCGCATTAACCATCCGGATCGCCTTAACTATCCCATGAAACGCGTTGGCCGCCGCGGCGAAGGCAAATTTGAACGCA
TTAGCTGGCAGGAAGCGCTGGACACCATTAGCGCCAGCCTGAAAAAGACCGTAGAGACCTACGGCAATGAAGCCGTTTAT
ATCCACTATTCATCCGGCATCGTAGGCGGCAACATAACCCGCTCGTCGCCTGCCGCCTCGCCGGTGAAGCGTTTGATGAA
CTGCTACGGCGGTTCGTTGAATCAATACGGCTCATACAGTACCGCGCAAATTTCTTGCGCCATGCCCTACACCTATGGCT
CCAACGACGGCAACAGCACGTCTGATATCGAAAACAGTAAACTGGTGGTCATGTTCGGCAATAATCCGGCTGAAACACGC
ATGAGCGGCGGCGGCATTACCTGGTTTCTGGAGCAAGCGCGTGAACGCTCAAATGCGCGCATGATCGTGATAGATCCGCG
CTATACCGATACCGCTGCCGGACGTGAAGACGAGTGGATACCGATTCGCCCCGGCACCGACGCCGCGCTGGTGGCGGGAA
TTGCCTGGGTATTGATTAACGAAAATCTCGTTGACCAGCCTTTTCTCGACAACTATTGCATCGGCTACGATGAAAAGACC
CTTCCGGCTGACGCGCCCCCCAATGGCCATTATAAGGCTTATATTTTGGGCCAGGGCGAGGACGGTATCGCCAAAACGCC
GCAGTGGGCGTCACACATTACCGGCATCCCCGCCGATCGGATTATCAAACTGGCGCGCGAGATAGGTAGCGTCAAGCCGG
CCTACATCTGTCAGGGTTGGGGGCCGCAGCGTCAGGCGAACGGCGAACAAACCGCTCGCGCCATCGCCATGTTACCGATT
CTGACCGGCAACGTCGGCATTCATGGCGGTAACAGCGGCGCACGCGAATCTACTTACACCATTACCATTGAACGTCTGCC
GGTCCTGGAGAATCCCGTTAAAACCGCCATCTCCTGCTTTAGCTGGACGGACGCCATTGCGCGCGGTCCGGAAATGACCG
CCCTGCGCGACGGCGTACGCGGCAAAGATAAACTGGATGTTCCGATCAAATTTCTATGGAACTACGCTGGCAACACCCTG
ATTAATCAGCATTCGGATATTAATAAAACCCATGAAATTCTTCAGGATGAAGCGAAATGCGAAATGATTGTGGTCATCGA
CAATTTTATGACCTCTTCCGCGAAGTACGCCGATATTTTACTGCCGGATCTCATGACCGTCGAACAGGAAGATATCATCC
CCAATGATTACGCCGGCAATATGGGATATCTGATTTTTATCCAACCGGCGACGACGCCTAAGTTCGAGCGCAAGCCCATC
TACTGGGTACTCAGCGAAATCGCCAGACGCCTCGGCGACGATGTGTATCAGCGGTTTACCGAAGGCCGTACCCAGGCGCA
ATGGCTGCAATATCTGTACGCCAAAATGCAGGCAAGAGATCCGGCATTGCCCGCGTATGACGAGCTGAAAAAAATGGGCA
TCTATAAACGCAAAGATCCCAACGGCCATTTTGTCGCCTATAAAAAATTTCGTGAAGATCCGCAGGCCAATCCGTTAAAA
ACGCCGTCCGGTAAAATCGAAATCTACTCAAGCAAACTCGCTCATATCGCCAGTACCTGGGAGCTGGCGGAAGGCGACGT
GATAAGCCCACTGCCGATTTATACCCCTACTTTTGAAGGATGGGACGATCCGAAGCGGAGCACCTTCCCGCTACAGCTGT
TTGGCTTTCACTATAAATCCCGTACCCATTCAAGCTACGGCAATATTGATGTTCTGCAGGCCGCCTGTCGCCAGGAGGTG
TGGATAAATCCGCTCGATGCGCAAAAACGCGGTATCGCGAATGGCGATAAGGTTCGCGTCTTTAACGATCGTGGAGAGGT
GCGTCTACCCGCCAAAGTCACGCCGCGTATTCTGCCCGGCGTCAGCGCGATGGGTCAGGGCGCATGGCATAATGCGGATA
TGGCTGGCGATAAAATTGACCACGGCGCCTGCATCAATACGCTCACGACGCTGCGTCCTTCCCCCCTGGCAAAAGGGAAT
CCTCAACATACAAATCTGGTGGAAATCGAAAAAATCTAA

Upstream 100 bases:

>100_bases
CTTACTCCCAAAGGGGTAAACTCATTACATCATTAGCATGTTAATAATTTCGTTATAGTTATCAATATATAGCGAAATAA
TAACGACAATGGAGTGAGTG

Downstream 100 bases:

>100_bases
GCCGCCTGCTCCGGGACGTTTTTACGCGCCCGGGGCTCCCCGTTTTGCGAACACAACAACATTTAAAACTCTTTTTTGGA
TGAGCATAGTGAGCTGTTAT

Product: anaerobic dimethyl sulfoxide reductase chain a

Products: NA

Alternate protein names: DMSO reductase [H]

Number of amino acids: Translated: 812; Mature: 811

Protein sequence:

>812_residues
MPGEKQQTGVSRRTLVKSAALGSLALAAGGVSLPFGMRTAAAAVQQAMRNEEDKIVWGACSVNCGSRCALRLHVKDNEVW
WVETDNTGDDVYGNHQVRACLRGRSIRRRINHPDRLNYPMKRVGRRGEGKFERISWQEALDTISASLKKTVETYGNEAVY
IHYSSGIVGGNITRSSPAASPVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDGNSTSDIENSKLVVMFGNNPAETR
MSGGGITWFLEQARERSNARMIVIDPRYTDTAAGREDEWIPIRPGTDAALVAGIAWVLINENLVDQPFLDNYCIGYDEKT
LPADAPPNGHYKAYILGQGEDGIAKTPQWASHITGIPADRIIKLAREIGSVKPAYICQGWGPQRQANGEQTARAIAMLPI
LTGNVGIHGGNSGARESTYTITIERLPVLENPVKTAISCFSWTDAIARGPEMTALRDGVRGKDKLDVPIKFLWNYAGNTL
INQHSDINKTHEILQDEAKCEMIVVIDNFMTSSAKYADILLPDLMTVEQEDIIPNDYAGNMGYLIFIQPATTPKFERKPI
YWVLSEIARRLGDDVYQRFTEGRTQAQWLQYLYAKMQARDPALPAYDELKKMGIYKRKDPNGHFVAYKKFREDPQANPLK
TPSGKIEIYSSKLAHIASTWELAEGDVISPLPIYTPTFEGWDDPKRSTFPLQLFGFHYKSRTHSSYGNIDVLQAACRQEV
WINPLDAQKRGIANGDKVRVFNDRGEVRLPAKVTPRILPGVSAMGQGAWHNADMAGDKIDHGACINTLTTLRPSPLAKGN
PQHTNLVEIEKI

Sequences:

>Translated_812_residues
MPGEKQQTGVSRRTLVKSAALGSLALAAGGVSLPFGMRTAAAAVQQAMRNEEDKIVWGACSVNCGSRCALRLHVKDNEVW
WVETDNTGDDVYGNHQVRACLRGRSIRRRINHPDRLNYPMKRVGRRGEGKFERISWQEALDTISASLKKTVETYGNEAVY
IHYSSGIVGGNITRSSPAASPVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDGNSTSDIENSKLVVMFGNNPAETR
MSGGGITWFLEQARERSNARMIVIDPRYTDTAAGREDEWIPIRPGTDAALVAGIAWVLINENLVDQPFLDNYCIGYDEKT
LPADAPPNGHYKAYILGQGEDGIAKTPQWASHITGIPADRIIKLAREIGSVKPAYICQGWGPQRQANGEQTARAIAMLPI
LTGNVGIHGGNSGARESTYTITIERLPVLENPVKTAISCFSWTDAIARGPEMTALRDGVRGKDKLDVPIKFLWNYAGNTL
INQHSDINKTHEILQDEAKCEMIVVIDNFMTSSAKYADILLPDLMTVEQEDIIPNDYAGNMGYLIFIQPATTPKFERKPI
YWVLSEIARRLGDDVYQRFTEGRTQAQWLQYLYAKMQARDPALPAYDELKKMGIYKRKDPNGHFVAYKKFREDPQANPLK
TPSGKIEIYSSKLAHIASTWELAEGDVISPLPIYTPTFEGWDDPKRSTFPLQLFGFHYKSRTHSSYGNIDVLQAACRQEV
WINPLDAQKRGIANGDKVRVFNDRGEVRLPAKVTPRILPGVSAMGQGAWHNADMAGDKIDHGACINTLTTLRPSPLAKGN
PQHTNLVEIEKI
>Mature_811_residues
PGEKQQTGVSRRTLVKSAALGSLALAAGGVSLPFGMRTAAAAVQQAMRNEEDKIVWGACSVNCGSRCALRLHVKDNEVWW
VETDNTGDDVYGNHQVRACLRGRSIRRRINHPDRLNYPMKRVGRRGEGKFERISWQEALDTISASLKKTVETYGNEAVYI
HYSSGIVGGNITRSSPAASPVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDGNSTSDIENSKLVVMFGNNPAETRM
SGGGITWFLEQARERSNARMIVIDPRYTDTAAGREDEWIPIRPGTDAALVAGIAWVLINENLVDQPFLDNYCIGYDEKTL
PADAPPNGHYKAYILGQGEDGIAKTPQWASHITGIPADRIIKLAREIGSVKPAYICQGWGPQRQANGEQTARAIAMLPIL
TGNVGIHGGNSGARESTYTITIERLPVLENPVKTAISCFSWTDAIARGPEMTALRDGVRGKDKLDVPIKFLWNYAGNTLI
NQHSDINKTHEILQDEAKCEMIVVIDNFMTSSAKYADILLPDLMTVEQEDIIPNDYAGNMGYLIFIQPATTPKFERKPIY
WVLSEIARRLGDDVYQRFTEGRTQAQWLQYLYAKMQARDPALPAYDELKKMGIYKRKDPNGHFVAYKKFREDPQANPLKT
PSGKIEIYSSKLAHIASTWELAEGDVISPLPIYTPTFEGWDDPKRSTFPLQLFGFHYKSRTHSSYGNIDVLQAACRQEVW
INPLDAQKRGIANGDKVRVFNDRGEVRLPAKVTPRILPGVSAMGQGAWHNADMAGDKIDHGACINTLTTLRPSPLAKGNP
QHTNLVEIEKI

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787870, Length=812, Percent_Identity=87.0689655172414, Blast_Score=1504, Evalue=0.0,
Organism=Escherichia coli, GI171474008, Length=805, Percent_Identity=71.4285714285714, Blast_Score=1230, Evalue=0.0,
Organism=Escherichia coli, GI87081797, Length=806, Percent_Identity=68.2382133995037, Blast_Score=1149, Evalue=0.0,
Organism=Escherichia coli, GI145693196, Length=779, Percent_Identity=30.2952503209243, Blast_Score=283, Evalue=3e-77,
Organism=Escherichia coli, GI1787231, Length=763, Percent_Identity=30.9305373525557, Blast_Score=273, Evalue=4e-74,
Organism=Escherichia coli, GI87081994, Length=856, Percent_Identity=28.3878504672897, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI3868721, Length=791, Percent_Identity=23.7673830594185, Blast_Score=128, Evalue=2e-30,
Organism=Escherichia coli, GI3868720, Length=460, Percent_Identity=25.6521739130435, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI3868719, Length=466, Percent_Identity=24.2489270386266, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1787741, Length=443, Percent_Identity=26.1851015801354, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788534, Length=887, Percent_Identity=22.435174746336, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011888
- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 90018; Mature: 89887

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGEKQQTGVSRRTLVKSAALGSLALAAGGVSLPFGMRTAAAAVQQAMRNEEDKIVWGAC
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEE
SVNCGSRCALRLHVKDNEVWWVETDNTGDDVYGNHQVRACLRGRSIRRRINHPDRLNYPM
ECCCCCEEEEEEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCH
KRVGRRGEGKFERISWQEALDTISASLKKTVETYGNEAVYIHYSSGIVGGNITRSSPAAS
HHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEECCCCCCCCCCHH
PVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDGNSTSDIENSKLVVMFGNNPAETR
HHHHHHHHHCCCCHHCCCCCCEEEEEEECEEECCCCCCCCCCCCCCEEEEEECCCCHHCE
MSGGGITWFLEQARERSNARMIVIDPRYTDTAAGREDEWIPIRPGTDAALVAGIAWVLIN
ECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHEEEEEEC
ENLVDQPFLDNYCIGYDEKTLPADAPPNGHYKAYILGQGEDGIAKTPQWASHITGIPADR
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHCCCCHHH
IIKLAREIGSVKPAYICQGWGPQRQANGEQTARAIAMLPILTGNVGIHGGNSGARESTYT
HHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHEEEEEECCEEEECCCCCCCCCEEE
ITIERLPVLENPVKTAISCFSWTDAIARGPEMTALRDGVRGKDKLDVPIKFLWNYAGNTL
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCHHHEEHHCCCCE
INQHSDINKTHEILQDEAKCEMIVVIDNFMTSSAKYADILLPDLMTVEQEDIIPNDYAGN
ECCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCC
MGYLIFIQPATTPKFERKPIYWVLSEIARRLGDDVYQRFTEGRTQAQWLQYLYAKMQARD
CEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
PALPAYDELKKMGIYKRKDPNGHFVAYKKFREDPQANPLKTPSGKIEIYSSKLAHIASTW
CCCCCHHHHHHCCCEECCCCCCCEEEEHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHH
ELAEGDVISPLPIYTPTFEGWDDPKRSTFPLQLFGFHYKSRTHSSYGNIDVLQAACRQEV
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
WINPLDAQKRGIANGDKVRVFNDRGEVRLPAKVTPRILPGVSAMGQGAWHNADMAGDKID
CCCCCCHHHCCCCCCCEEEEECCCCCEEECCCCCCHHCCCCHHHCCCCCCCCCCCCCCCC
HGACINTLTTLRPSPLAKGNPQHTNLVEIEKI
CCHHHHHHHHCCCCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
PGEKQQTGVSRRTLVKSAALGSLALAAGGVSLPFGMRTAAAAVQQAMRNEEDKIVWGAC
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEE
SVNCGSRCALRLHVKDNEVWWVETDNTGDDVYGNHQVRACLRGRSIRRRINHPDRLNYPM
ECCCCCEEEEEEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCH
KRVGRRGEGKFERISWQEALDTISASLKKTVETYGNEAVYIHYSSGIVGGNITRSSPAAS
HHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEECCCCCCCCCCHH
PVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDGNSTSDIENSKLVVMFGNNPAETR
HHHHHHHHHCCCCHHCCCCCCEEEEEEECEEECCCCCCCCCCCCCCEEEEEECCCCHHCE
MSGGGITWFLEQARERSNARMIVIDPRYTDTAAGREDEWIPIRPGTDAALVAGIAWVLIN
ECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHEEEEEEC
ENLVDQPFLDNYCIGYDEKTLPADAPPNGHYKAYILGQGEDGIAKTPQWASHITGIPADR
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHCCCCHHH
IIKLAREIGSVKPAYICQGWGPQRQANGEQTARAIAMLPILTGNVGIHGGNSGARESTYT
HHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHEEEEEECCEEEECCCCCCCCCEEE
ITIERLPVLENPVKTAISCFSWTDAIARGPEMTALRDGVRGKDKLDVPIKFLWNYAGNTL
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCHHHEEHHCCCCE
INQHSDINKTHEILQDEAKCEMIVVIDNFMTSSAKYADILLPDLMTVEQEDIIPNDYAGN
ECCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCC
MGYLIFIQPATTPKFERKPIYWVLSEIARRLGDDVYQRFTEGRTQAQWLQYLYAKMQARD
CEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
PALPAYDELKKMGIYKRKDPNGHFVAYKKFREDPQANPLKTPSGKIEIYSSKLAHIASTW
CCCCCHHHHHHCCCEECCCCCCCEEEEHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHH
ELAEGDVISPLPIYTPTFEGWDDPKRSTFPLQLFGFHYKSRTHSSYGNIDVLQAACRQEV
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
WINPLDAQKRGIANGDKVRVFNDRGEVRLPAKVTPRILPGVSAMGQGAWHNADMAGDKID
CCCCCCHHHCCCCCCCEEEEECCCCCEEECCCCCCHHCCCCHHHCCCCCCCCCCCCCCCC
HGACINTLTTLRPSPLAKGNPQHTNLVEIEKI
CCHHHHHHHHCCCCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]