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The map label for this gene is sopD [H]

Identifier: 194738039

GI number: 194738039

Start: 2992197

End: 2993279

Strand: Direct

Name: sopD [H]

Synonym: SeSA_A3099

Alternate gene names: 194738039

Gene position: 2992197-2993279 (Clockwise)

Preceding gene: 194736786

Following gene: 194738118

Centisome position: 63.54

GC content: 39.43

Gene sequence:

>1083_bases
ATGTGCTGTATTGATAATGCCGTTCAAATTCTCTCCTGTAGTAAACCTTGTCTATTTAATAAAAAAGAGGGAGTTGAACG
ATATATTTTACTCCGGATATTGAATAATATAAATTTGAAGGAAAATATTATGCCAGTCACTTTAAGCTTCGGTAATCATC
AAAATTATACGCTTAATGAAAGTCGGCTTGCTCATCTGTTAAGCGCAGATAAAGAAAAAGCAATCCATATGGGGGGCTGG
GATAAAGTCCAGGATCATTTTAGAGCGGAAAAAAAGGACCATGCGCTGGAAGTGTTACACTCCATCATTCACGGTCAGGG
CCGTGGTGAACCTGGAGAGATGGAAGTTAACGTAGAGGATATAAATAAAATTTACGCCTTTAAACGGCTACAACATCTGG
CCTGCCCGGCTCATCAGGATCTGTTTACTATCAAGATGGATGCCTCTCAGACACAATTTTTACTTATGGTCGGCGACACG
ATGATCAGCCAAAGCAATATTAAGGACATCCTCAATATATCAGATGATACAGTGATAGAATCTATGAGTAGAGAGGAGAG
ACAGTTATTTTTACAAATATGTGAGGTGATTGGTTCGAAGATGACCTGGCACCCGGAATTACTTCAGGAGTCGATTTCAA
CTCTACGAAAAGAAGTGACGAGCAATGCACAAATCAAAGTGGCGGTTTATGAGATGATGCGTCCCGCAGAGGCTCCAGAC
CACCCGCTTGTCGAATGGCAGGACTCACTTACTGCAGATGAAAAATCGATGCTGGCCTGTATTAATGCCGGTAACTTTGA
GCCTACAACTCAGTTTTGCAAAATAGGTTATCAGGAGGTACAAGGTGAAGTCGCTTTTAGCATGATGCATCCGTGCATCT
CCTATTTACTACATAGCTATTCACCGTTTGCAGAGTTTAAACCAACAAATTCTGGTTTTTTAAAAAAACTTAATCAGGAT
TATAACGACTATCATGCAAAAAAAATGTTTATTGATGTAATTCTTGAAAAGATATATCTAACGCATGAACGTTCTTTGCA
CATTGGTAAAGATGGGTGCAGTCGTAATATATTACTGACATAA

Upstream 100 bases:

>100_bases
ACCATTCATGACAAACCAAAATTTAAAAAAACGACCATTTGCGGCGAATCATCTACCTTTTGTCTGAATTATCGTCACCA
CAAAGGATTACCAACCATAA

Downstream 100 bases:

>100_bases
AGATAGTCAGTAAAATAACTAATTTAAAATCCGGCTGCCTGCCGGATTTTTCATAGCAGCAAGTATAATTATACCGCGTA
AGGACAATTACCCTTCATGC

Product: Sop effector protein SopD

Products: NA

Alternate protein names: Salmonella outer protein D [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MCCIDNAVQILSCSKPCLFNKKEGVERYILLRILNNINLKENIMPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGW
DKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDT
MISQSNIKDILNISDDTVIESMSREERQLFLQICEVIGSKMTWHPELLQESISTLRKEVTSNAQIKVAVYEMMRPAEAPD
HPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHSYSPFAEFKPTNSGFLKKLNQD
YNDYHAKKMFIDVILEKIYLTHERSLHIGKDGCSRNILLT

Sequences:

>Translated_360_residues
MCCIDNAVQILSCSKPCLFNKKEGVERYILLRILNNINLKENIMPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGW
DKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDT
MISQSNIKDILNISDDTVIESMSREERQLFLQICEVIGSKMTWHPELLQESISTLRKEVTSNAQIKVAVYEMMRPAEAPD
HPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHSYSPFAEFKPTNSGFLKKLNQD
YNDYHAKKMFIDVILEKIYLTHERSLHIGKDGCSRNILLT
>Mature_360_residues
MCCIDNAVQILSCSKPCLFNKKEGVERYILLRILNNINLKENIMPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGW
DKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDT
MISQSNIKDILNISDDTVIESMSREERQLFLQICEVIGSKMTWHPELLQESISTLRKEVTSNAQIKVAVYEMMRPAEAPD
HPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHSYSPFAEFKPTNSGFLKKLNQD
YNDYHAKKMFIDVILEKIYLTHERSLHIGKDGCSRNILLT

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Contributes to replication in macrophages. Plays a role, cooperatively with sopB, in membrane fission and macropinosome formation during invasion [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cytoplasm. Host cell membrane. Note=Secreted via type III secretion systems 1 and 2 (SPI-1 and SPI-2 TTSS), and delivered into the host cell (Probable). Membrane-associated in transfected cells. Recruited to the bacterial invasion site, and

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sopD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022747
- ProDom:   PD040905 [H]

Pfam domain/function: PF11047 SopD [H]

EC number: NA

Molecular weight: Translated: 41166; Mature: 41166

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCCIDNAVQILSCSKPCLFNKKEGVERYILLRILNNINLKENIMPVTLSFGNHQNYTLNE
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEECH
SRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVED
HHHHHHHHCCHHCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHH
INKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTMISQSNIKDILNISDDTVIE
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHH
SMSREERQLFLQICEVIGSKMTWHPELLQESISTLRKEVTSNAQIKVAVYEMMRPAEAPD
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCCC
HPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHSY
CCCHHHHHHCCCCHHHHEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
SPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKIYLTHERSLHIGKDGCSRNILLT
CCCHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEC
>Mature Secondary Structure
MCCIDNAVQILSCSKPCLFNKKEGVERYILLRILNNINLKENIMPVTLSFGNHQNYTLNE
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEECH
SRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVED
HHHHHHHHCCHHCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHH
INKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTMISQSNIKDILNISDDTVIE
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHH
SMSREERQLFLQICEVIGSKMTWHPELLQESISTLRKEVTSNAQIKVAVYEMMRPAEAPD
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCCC
HPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHSY
CCCHHHHHHCCCCHHHHEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
SPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKIYLTHERSLHIGKDGCSRNILLT
CCCHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2670946; 11677609 [H]