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The map label for this gene is luxS [H]

Identifier: 194738022

GI number: 194738022

Start: 2873597

End: 2874112

Strand: Reverse

Name: luxS [H]

Synonym: SeSA_A2966

Alternate gene names: 194738022

Gene position: 2874112-2873597 (Counterclockwise)

Preceding gene: 194737520

Following gene: 194738374

Centisome position: 61.03

GC content: 52.91

Gene sequence:

>516_bases
ATGCCATTATTAGATAGCTTCGCAGTCGATCATACCCGGATGCAAGCGCCGGCGGTCCGGGTTGCAAAAACGATGAACAC
CCCGCATGGCGACGCAATCACCGTGTTTGATCTGCGTTTTTGCATTCCGAACAAAGAAGTGATGCCGGAAAAAGGGATTC
ATACGCTTGAGCATCTGTTTGCTGGCTTTATGCGCGACCACCTCAACGGTAACGGCGTTGAGATTATCGATATCTCGCCG
ATGGGCTGCCGTACCGGTTTCTACATGAGCCTGATTGGCACGCCGGACGAGCAGCGTGTTGCCGACGCGTGGAAAGCGGC
GATGGCGGATGTGCTGAAAGTGCAGGATCAAAACCAGATCCCGGAGCTGAACGTTTACCAGTGCGGTACGTATCAGATGC
ACTCGCTCAGTGAAGCGCAGGACATTGCCCGTCATATTCTGGAGCGTGATGTACGCGTGAACAGCAATAAAGAGCTGGCG
CTACCGAAAGAAAAACTGCAGGAACTGCATATTTAG

Upstream 100 bases:

>100_bases
AACAGGGATGATGATAACAAATGCGCGTCTTTCATATACTCAGACTCGCCCCGGAACAAAGAGTTCAGTTTATTTTTAAA
AAATTATCGGAGGTGACTAA

Downstream 100 bases:

>100_bases
TCTTATTGGTAAGCGGTTCCAGTATTTAAATTAACCCCGGTTTATGGCCGGGGTTTTTTATTGCTTAATATAATTTGCGT
TTATTATATTTGCGGCGAGA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MPLLDSFAVDHTRMQAPAVRVAKTMNTPHGDAITVFDLRFCIPNKEVMPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISP
MGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVQDQNQIPELNVYQCGTYQMHSLSEAQDIARHILERDVRVNSNKELA
LPKEKLQELHI

Sequences:

>Translated_171_residues
MPLLDSFAVDHTRMQAPAVRVAKTMNTPHGDAITVFDLRFCIPNKEVMPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISP
MGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVQDQNQIPELNVYQCGTYQMHSLSEAQDIARHILERDVRVNSNKELA
LPKEKLQELHI
>Mature_170_residues
PLLDSFAVDHTRMQAPAVRVAKTMNTPHGDAITVFDLRFCIPNKEVMPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISPM
GCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVQDQNQIPELNVYQCGTYQMHSLSEAQDIARHILERDVRVNSNKELAL
PKEKLQELHI

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=171, Percent_Identity=94.1520467836257, Blast_Score=345, Evalue=8e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 19308; Mature: 19177

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFAVDHTRMQAPAVRVAKTMNTPHGDAITVFDLRFCIPNKEVMPEKGIHTLEHLF
CCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHH
AGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVQDQNQI
HHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
PELNVYQCGTYQMHSLSEAQDIARHILERDVRVNSNKELALPKEKLQELHI
CCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHCCC
>Mature Secondary Structure 
PLLDSFAVDHTRMQAPAVRVAKTMNTPHGDAITVFDLRFCIPNKEVMPEKGIHTLEHLF
CCCHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHH
AGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVQDQNQI
HHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
PELNVYQCGTYQMHSLSEAQDIARHILERDVRVNSNKELALPKEKLQELHI
CCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA