Click here to switch to the map view.

The map label for this gene is modF [H]

Identifier: 194737990

GI number: 194737990

Start: 899029

End: 900504

Strand: Reverse

Name: modF [H]

Synonym: SeSA_A0928

Alternate gene names: 194737990

Gene position: 900504-899029 (Counterclockwise)

Preceding gene: 194736128

Following gene: 194737516

Centisome position: 19.12

GC content: 54.61

Gene sequence:

>1476_bases
ATGTCATCGTTGCAAATTTCGCAAGGCACGTTTCGTCTGAGCGATACAAAAACACTTCATCTGGATTCGCTGACGCTCAA
TGCGGGCGATAGCTGGGCATTCGTTGGGGCTAACGGGAGCGGGAAGTCGGCGCTCGCCCGCGCGCTGGCGGGTGAACTGC
CATTATTAACAGGCGAGCGCCAGTGTCAGTTTACCCGCATTACTCGTCTGTCCTTTGAACAATTGCAAAAGCTGGTCAGC
GATGAATGGCAACGTAATAACACCGATATGCTCAGTCCTGGCGAAGACGATACCGGGCGCACTACCGCGGAAATTATTCA
GGATGATGTTCACCATCCTGCCCGCTGTGCGATGCTGGCGCAGCAGTTCGGCATTTCCGCTTTACTCAACAGGCGTTTTA
AATACCTTTCTACCGGCGAGACGCGAAAAGCGCTGCTGTGTCAGGCGATGATGTCTGAGCCGGAGTTATTGATCCTTGAT
GAACCGTTCGACGGGCTTGACGTGACCGCCCGTCAACAACTGGCGCAACGCCTGACGGCGTTGAACCAGGCGGGTATTAC
CCTGGCGCTGGTACTCAACCGTTTTGATGAAATCCCGGACTTCGTGCAGTTTGCCGGCGTGCTTGCCGACTGTACGCTGG
CGGAAACCGGAACGACGACAGAGTTACTGCAACGGGCGTTGGTCGCTCAACTCGCGCACAGCGAGCGTCTGACAGACGTA
CAATTACCCGAACCGGACCAACCTTCCGCCCGCCATGCGTTACCCGATGGCGAACCACGGATCGTACTTAACGATGGCGT
AGTCTCGTATAACGATCGCCCTATCCTCCACCACCTAAGCTGGCGAGTAAATCCAGGCGAACACTGGCAGATCGTCGGTC
CTAACGGAGCGGGTAAGTCTACGTTGCTTAGCCTTATTACTGGCGATCATCCGCAAGGCTACAGCAACGATCTTACGCTG
TTCGGGCGGCGGCGAGGAAGCGGCGAAACAATCTGGGATATCAAAAAACATATCGGCTACGTCAGCAGCAGTTTACATCT
GGATTACCGCGTCAGTACCACGGTACGCAATGTCATTCTCTCCGGCTATTTCGATTCTATCGGCATTTACCAGGCCGTTT
CAGACAGGCAACGAAAACTGGCGCAACAGTGGCTGGATATTCTGGGAATCGATAAGCGCACGGCGGATGCCCCTTTCCAC
AGTCTCTCCTGGGGACAGCAGCGGCTGGCGCTGATCGTGCGCGCGCTGGTTAAACATCCGACAGTGTTGATTCTGGATGA
ACCGCTGCAAGGGTTGGATCCGCTGAACCGCCAACTGGTACGCCGTTTTGTGGATGTATTAATTCGCCAGGGAGAGACCC
AACTGCTGTTCGTTTCCCATCATGCAGAGGATGCGCCTGCCTGTATTACCCACCGACTGGAATTTGTACCAGAGGGCGAA
AGCTATAAGTACGTTTCCGGACGATGCAATAATTAA

Upstream 100 bases:

>100_bases
GCGGACAGAGTGATTATTGCAACGTTGTGCTAAGCACATTGACATCCGTTGCCGAAAGACGTATCCCTGTCATTCATCGC
TGCAAAAAATGGGATGCAAA

Downstream 100 bases:

>100_bases
ATGTATTATCAGAATGGCGCCGCGCGCCATTCTGGAACCACTCTCCTTTTATTATGAATAATAATAACGGTCGATAAGCT
TACTATCTCTTGAATCGCTG

Product: putative molybdenum transport ATP-binding protein ModF

Products: NA

Alternate protein names: Photorepair protein PhrA [H]

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MSSLQISQGTFRLSDTKTLHLDSLTLNAGDSWAFVGANGSGKSALARALAGELPLLTGERQCQFTRITRLSFEQLQKLVS
DEWQRNNTDMLSPGEDDTGRTTAEIIQDDVHHPARCAMLAQQFGISALLNRRFKYLSTGETRKALLCQAMMSEPELLILD
EPFDGLDVTARQQLAQRLTALNQAGITLALVLNRFDEIPDFVQFAGVLADCTLAETGTTTELLQRALVAQLAHSERLTDV
QLPEPDQPSARHALPDGEPRIVLNDGVVSYNDRPILHHLSWRVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQRKLAQQWLDILGIDKRTADAPFH
SLSWGQQRLALIVRALVKHPTVLILDEPLQGLDPLNRQLVRRFVDVLIRQGETQLLFVSHHAEDAPACITHRLEFVPEGE
SYKYVSGRCNN

Sequences:

>Translated_491_residues
MSSLQISQGTFRLSDTKTLHLDSLTLNAGDSWAFVGANGSGKSALARALAGELPLLTGERQCQFTRITRLSFEQLQKLVS
DEWQRNNTDMLSPGEDDTGRTTAEIIQDDVHHPARCAMLAQQFGISALLNRRFKYLSTGETRKALLCQAMMSEPELLILD
EPFDGLDVTARQQLAQRLTALNQAGITLALVLNRFDEIPDFVQFAGVLADCTLAETGTTTELLQRALVAQLAHSERLTDV
QLPEPDQPSARHALPDGEPRIVLNDGVVSYNDRPILHHLSWRVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQRKLAQQWLDILGIDKRTADAPFH
SLSWGQQRLALIVRALVKHPTVLILDEPLQGLDPLNRQLVRRFVDVLIRQGETQLLFVSHHAEDAPACITHRLEFVPEGE
SYKYVSGRCNN
>Mature_490_residues
SSLQISQGTFRLSDTKTLHLDSLTLNAGDSWAFVGANGSGKSALARALAGELPLLTGERQCQFTRITRLSFEQLQKLVSD
EWQRNNTDMLSPGEDDTGRTTAEIIQDDVHHPARCAMLAQQFGISALLNRRFKYLSTGETRKALLCQAMMSEPELLILDE
PFDGLDVTARQQLAQRLTALNQAGITLALVLNRFDEIPDFVQFAGVLADCTLAETGTTTELLQRALVAQLAHSERLTDVQ
LPEPDQPSARHALPDGEPRIVLNDGVVSYNDRPILHHLSWRVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLF
GRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQRKLAQQWLDILGIDKRTADAPFHS
LSWGQQRLALIVRALVKHPTVLILDEPLQGLDPLNRQLVRRFVDVLIRQGETQLLFVSHHAEDAPACITHRLEFVPEGES
YKYVSGRCNN

Specific function: Involved in the transport of molybdenum into the cell. Involved in photorepair. Could act on UV-induced DNA damage other than pyrimidine dimers [H]

COG id: COG1119

COG function: function code P; ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI27262624, Length=193, Percent_Identity=26.4248704663212, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI27262626, Length=193, Percent_Identity=26.4248704663212, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1786975, Length=485, Percent_Identity=88.4536082474227, Blast_Score=884, Evalue=0.0,
Organism=Escherichia coli, GI48994943, Length=380, Percent_Identity=27.3684210526316, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1788897, Length=499, Percent_Identity=23.0460921843687, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787041, Length=521, Percent_Identity=22.4568138195777, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789991, Length=484, Percent_Identity=22.1074380165289, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48995001, Length=463, Percent_Identity=24.1900647948164, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693107, Length=501, Percent_Identity=25.1497005988024, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87081782, Length=534, Percent_Identity=24.1573033707865, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1790525, Length=489, Percent_Identity=21.4723926380368, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787792, Length=481, Percent_Identity=24.1164241164241, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788165, Length=228, Percent_Identity=29.8245614035088, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786253, Length=209, Percent_Identity=33.4928229665072, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790190, Length=469, Percent_Identity=23.8805970149254, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790544, Length=228, Percent_Identity=30.2631578947368, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787029, Length=206, Percent_Identity=30.5825242718447, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788225, Length=209, Percent_Identity=28.2296650717703, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789593, Length=222, Percent_Identity=27.9279279279279, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786319, Length=192, Percent_Identity=29.6875, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1786703, Length=200, Percent_Identity=31.5, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788472, Length=454, Percent_Identity=20.9251101321586, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789864, Length=216, Percent_Identity=25, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786563, Length=234, Percent_Identity=26.9230769230769, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787089, Length=213, Percent_Identity=28.169014084507, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1787112, Length=229, Percent_Identity=28.3842794759825, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=281, Percent_Identity=27.7580071174377, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6320266, Length=393, Percent_Identity=29.2620865139949, Blast_Score=157, Evalue=5e-39,
Organism=Drosophila melanogaster, GI19920532, Length=183, Percent_Identity=30.6010928961749, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24580930, Length=183, Percent_Identity=30.6010928961749, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24650853, Length=197, Percent_Identity=29.9492385786802, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24650855, Length=197, Percent_Identity=29.9492385786802, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI28574744, Length=235, Percent_Identity=25.9574468085106, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281362751, Length=197, Percent_Identity=29.9492385786802, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221512771, Length=200, Percent_Identity=27.5, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 54647; Mature: 54515

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLQISQGTFRLSDTKTLHLDSLTLNAGDSWAFVGANGSGKSALARALAGELPLLTGER
CCCCCCCCCEEEECCCCEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCC
QCQFTRITRLSFEQLQKLVSDEWQRNNTDMLSPGEDDTGRTTAEIIQDDVHHPARCAMLA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
QQFGISALLNRRFKYLSTGETRKALLCQAMMSEPELLILDEPFDGLDVTARQQLAQRLTA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LNQAGITLALVLNRFDEIPDFVQFAGVLADCTLAETGTTTELLQRALVAQLAHSERLTDV
HHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCEECCCCCHHHHHHHHHHHHHHHHCCCCCC
QLPEPDQPSARHALPDGEPRIVLNDGVVSYNDRPILHHLSWRVNPGEHWQIVGPNGAGKS
CCCCCCCCCCCCCCCCCCCEEEEECCEEEECCCCEEEEEEEEECCCCCEEEECCCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVIL
HHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHH
SGYFDSIGIYQAVSDRQRKLAQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TVLILDEPLQGLDPLNRQLVRRFVDVLIRQGETQLLFVSHHAEDAPACITHRLEFVPEGE
EEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCC
SYKYVSGRCNN
CEEEECCCCCC
>Mature Secondary Structure 
SSLQISQGTFRLSDTKTLHLDSLTLNAGDSWAFVGANGSGKSALARALAGELPLLTGER
CCCCCCCCEEEECCCCEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCC
QCQFTRITRLSFEQLQKLVSDEWQRNNTDMLSPGEDDTGRTTAEIIQDDVHHPARCAMLA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
QQFGISALLNRRFKYLSTGETRKALLCQAMMSEPELLILDEPFDGLDVTARQQLAQRLTA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LNQAGITLALVLNRFDEIPDFVQFAGVLADCTLAETGTTTELLQRALVAQLAHSERLTDV
HHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCEECCCCCHHHHHHHHHHHHHHHHCCCCCC
QLPEPDQPSARHALPDGEPRIVLNDGVVSYNDRPILHHLSWRVNPGEHWQIVGPNGAGKS
CCCCCCCCCCCCCCCCCCCEEEEECCEEEECCCCEEEEEEEEECCCCCEEEECCCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVIL
HHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHH
SGYFDSIGIYQAVSDRQRKLAQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TVLILDEPLQGLDPLNRQLVRRFVDVLIRQGETQLLFVSHHAEDAPACITHRLEFVPEGE
EEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCC
SYKYVSGRCNN
CEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8564363; 8550508; 8905232; 9278503; 8310005 [H]