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The map label for this gene is gap [H]

Identifier: 194737977

GI number: 194737977

Start: 2069588

End: 2070583

Strand: Reverse

Name: gap [H]

Synonym: SeSA_A2179

Alternate gene names: 194737977

Gene position: 2070583-2069588 (Counterclockwise)

Preceding gene: 194735050

Following gene: 194734789

Centisome position: 43.97

GC content: 43.67

Gene sequence:

>996_bases
ATGGCTATTAAAGTAGGTATTAATGGTTTTGGGCGTATCGGTCGCACGGTTTTTCGTGAAGCGCAAAAACGCTCTGATAT
AGAAATTGTGGCAATTAACGATCTGTTAGATGTTAACTATATGGCGTATATGCTGAAGTATGACTCCACTCATGGTCGCT
TTGATGGCACTATTGAAGTAGATAATGGTCAGTTAATTGTTAACGGTAAAATAATCCGTGTTACCACTGAACGCGATCCG
AATAACCTGAAATGGGGTGAGATCGGTGTTGATGTTGTTGCTGAAGCAACCGGTATTTTCCTGACCGATGAAACTGCTCG
CAAGCATATCACTTCTGGTGCAAGGAAAGTTGTTCTGACTGGTCCGTCAAAAGACAATACTCCAATGTTTGTGAAGGGAG
TAAACTTTGACAAGTATAGAGGGCAGGATATTGTTTCGAATACATCATGTACAACTAACTGTTTGGCTCCACTGGCCAAA
GTCATCAACGACAACTTTGGAATCATTGAGGGGTTAATGACCACCGTCCACGCAACCACGGCGACCCAGAAAACCGTTGA
CGGCCCGTCTCATAAAGACTGGCGTGGTGGTCGCGGTGCGGCTCAGAACATCATCCCTTCCTCTACTGGTGCAGCTAAAG
CCGTAGGTAAAGTTCTACCGGAACTGAACGGAAAATTGACGGGCATGGCGTTCCGCATTCCGACTCCTAACGTTTCTGTT
GTTGATCTGACTGTTCGCCTGGAAAAAGCGGCTTCTTATGAAGATATTAAGAAAGTAATCAAGGCTGCTTCTGAAGGCTC
AATGAAAGGCATTCTGGGTTACACTGAAGATGACGTTGTTTCTACAGACTTCAATGGTGAAGTTTGTACTTCCGTGTTCG
ATGCAAAAGCAAGTATTGCTTTGAACGACAACTTCGTAAAACTGGTTTCCTGGTATGATAATGAAACTGGTTACTCAAAT
AAGGTTCTGGACTTAATCACCCATATTTCCAGATAA

Upstream 100 bases:

>100_bases
GACTAGTCACTAATAGAGATATTGCACCTTTTTTTGAAGAGCTGGTGCAATTATAAGTCTACAGATGACATTTTATTTAC
TGATAAGTAATGGATGAATT

Downstream 100 bases:

>100_bases
GCTAAGATAACCAACGGTTCTAAAAAGGCAGCTTCGGCCGCCTTTTTAGTTCTTATAATATAATTCATATTCCTGAGAGT
CAGACTACTTTCTCTTACCC

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH-A [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MAIKVGINGFGRIGRTVFREAQKRSDIEIVAINDLLDVNYMAYMLKYDSTHGRFDGTIEVDNGQLIVNGKIIRVTTERDP
NNLKWGEIGVDVVAEATGIFLTDETARKHITSGARKVVLTGPSKDNTPMFVKGVNFDKYRGQDIVSNTSCTTNCLAPLAK
VINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGAAQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRIPTPNVSV
VDLTVRLEKAASYEDIKKVIKAASEGSMKGILGYTEDDVVSTDFNGEVCTSVFDAKASIALNDNFVKLVSWYDNETGYSN
KVLDLITHISR

Sequences:

>Translated_331_residues
MAIKVGINGFGRIGRTVFREAQKRSDIEIVAINDLLDVNYMAYMLKYDSTHGRFDGTIEVDNGQLIVNGKIIRVTTERDP
NNLKWGEIGVDVVAEATGIFLTDETARKHITSGARKVVLTGPSKDNTPMFVKGVNFDKYRGQDIVSNTSCTTNCLAPLAK
VINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGAAQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRIPTPNVSV
VDLTVRLEKAASYEDIKKVIKAASEGSMKGILGYTEDDVVSTDFNGEVCTSVFDAKASIALNDNFVKLVSWYDNETGYSN
KVLDLITHISR
>Mature_330_residues
AIKVGINGFGRIGRTVFREAQKRSDIEIVAINDLLDVNYMAYMLKYDSTHGRFDGTIEVDNGQLIVNGKIIRVTTERDPN
NLKWGEIGVDVVAEATGIFLTDETARKHITSGARKVVLTGPSKDNTPMFVKGVNFDKYRGQDIVSNTSCTTNCLAPLAKV
INDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGAAQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRIPTPNVSVV
DLTVRLEKAASYEDIKKVIKAASEGSMKGILGYTEDDVVSTDFNGEVCTSVFDAKASIALNDNFVKLVSWYDNETGYSNK
VLDLITHISR

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=330, Percent_Identity=66.3636363636364, Blast_Score=459, Evalue=1e-129,
Organism=Homo sapiens, GI7657116, Length=330, Percent_Identity=61.2121212121212, Blast_Score=422, Evalue=1e-118,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=89.7280966767372, Blast_Score=623, Evalue=1e-180,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=40.1215805471125, Blast_Score=264, Evalue=7e-72,
Organism=Caenorhabditis elegans, GI17568413, Length=334, Percent_Identity=65.5688622754491, Blast_Score=439, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI32566163, Length=334, Percent_Identity=65.5688622754491, Blast_Score=439, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17534677, Length=334, Percent_Identity=65.2694610778443, Blast_Score=437, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17534679, Length=334, Percent_Identity=64.6706586826347, Blast_Score=435, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=65.2567975830816, Blast_Score=444, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=64.9546827794562, Blast_Score=439, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=63.7462235649547, Blast_Score=436, Evalue=1e-123,
Organism=Drosophila melanogaster, GI17933600, Length=328, Percent_Identity=65.2439024390244, Blast_Score=440, Evalue=1e-124,
Organism=Drosophila melanogaster, GI18110149, Length=328, Percent_Identity=65.2439024390244, Blast_Score=440, Evalue=1e-124,
Organism=Drosophila melanogaster, GI85725000, Length=328, Percent_Identity=65.2439024390244, Blast_Score=439, Evalue=1e-123,
Organism=Drosophila melanogaster, GI22023983, Length=328, Percent_Identity=65.2439024390244, Blast_Score=439, Evalue=1e-123,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=65.0306748466258, Blast_Score=433, Evalue=1e-122,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35896; Mature: 35765

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKVGINGFGRIGRTVFREAQKRSDIEIVAINDLLDVNYMAYMLKYDSTHGRFDGTIEV
CEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHEEEEEEECCCCCCCCCEEEE
DNGQLIVNGKIIRVTTERDPNNLKWGEIGVDVVAEATGIFLTDETARKHITSGARKVVLT
CCCEEEECCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEECHHHHHHHHCCCCEEEEE
GPSKDNTPMFVKGVNFDKYRGQDIVSNTSCTTNCLAPLAKVINDNFGIIEGLMTTVHATT
CCCCCCCCEEEECCCCCHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
ATQKTVDGPSHKDWRGGRGAAQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRIPTPNVSV
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEE
VDLTVRLEKAASYEDIKKVIKAASEGSMKGILGYTEDDVVSTDFNGEVCTSVFDAKASIA
EEEEEEECHHCCHHHHHHHHHHCCCCCCCEEECCCCCCEEECCCCCHHHHHHHCCCEEEE
LNDNFVKLVSWYDNETGYSNKVLDLITHISR
ECCCEEEEEEEECCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AIKVGINGFGRIGRTVFREAQKRSDIEIVAINDLLDVNYMAYMLKYDSTHGRFDGTIEV
EEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHEEEEEEECCCCCCCCCEEEE
DNGQLIVNGKIIRVTTERDPNNLKWGEIGVDVVAEATGIFLTDETARKHITSGARKVVLT
CCCEEEECCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEECHHHHHHHHCCCCEEEEE
GPSKDNTPMFVKGVNFDKYRGQDIVSNTSCTTNCLAPLAKVINDNFGIIEGLMTTVHATT
CCCCCCCCEEEECCCCCHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
ATQKTVDGPSHKDWRGGRGAAQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRIPTPNVSV
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEE
VDLTVRLEKAASYEDIKKVIKAASEGSMKGILGYTEDDVVSTDFNGEVCTSVFDAKASIA
EEEEEEECHHCCHHHHHHHHHHCCCCCCCEEECCCCCCEEECCCCCHHHHHHHCCCEEEE
LNDNFVKLVSWYDNETGYSNKVLDLITHISR
ECCCEEEEEEEECCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]