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The map label for this gene is cysM [H]

Identifier: 194737913

GI number: 194737913

Start: 523224

End: 524279

Strand: Reverse

Name: cysM [H]

Synonym: SeSA_A0517

Alternate gene names: 194737913

Gene position: 524279-523224 (Counterclockwise)

Preceding gene: 194736105

Following gene: 194738291

Centisome position: 11.13

GC content: 55.02

Gene sequence:

>1056_bases
ATGATGAGTAGCAATTGGGTTAAAAATGCCATTAATGAAATTAACGCTGACCACCAGCGCTCGGCGGATACGCATCTTAT
TCGTTTGCCCCTGTCGGCATTTCCGGGTATCCAGCTTTACCTGAAAGACGAAAGCACGCATCCCACCGGTAGCCTCAAGC
ATCGTCTGGCGCGCTCGCTGTTCCTTTATGGGCTGTGCAATGGCTGGATTAAAGAAGGCACTCCGATTATTGAAGCGTCA
TCAGGCTCAACGGCGATTTCCGAAGCCTGGTTCGCGCGTTTACTGGGACTGCCGTTCATCGCCGTCATGCCCGCCTGTAC
CGCAAAACGTAAAATCGAACAGATTCAATTTTACGGCGGCCACTGTCATTTTGTGGAGAGCGCCTGCGAAATTTATGCCG
CCTCCGAGCGGCTGGCGCATGAACTGAACGGTCACTATATGGACCAGTTTACCTACGCAGAACGAGCTACCGACTGGCGG
GGCAACAATAATATTGCCGACAGTATTTTCCGCCAGATGCGCAACGAACCCCATCCGGTACCGCGATTTATCGTCATGAG
CGCCGGAACGGGCGGAACCTCTGCGACGATTGGGCGCTATATTCGCTGCCAGGGCTATGATACTCAGCTCATGGTGGTGG
ATCCGGAAAATTCCGTCTTTTTACCTTACTGGCAGGATCGCGACGCTTCATTACGCAGCCCGGTGGGCAGTAAAATTGAA
GGAATTGGTCGTCCGCGAGTAGAGCCTTCTTTTATTCCGGATGTCGTGGATGAGATGCTGCGCGTGCCGGACGCCGCCAG
CGTTGCCACCGCACACTGGCTGGAAACGCAGCTAGGCCGTAAAGTCGGCGCCTCTACCGGCACGAATATGTGGGGAGCGC
TGCAGCTTGCGGCCCGGATGCGCGAGGCTGGAGAAACCGGCGCTATCGTGACGTTATTGTGCGATAGCGGCGATCGCTAT
CTGGATACCTATTACCATCCGTCCTGGGTTAGCGACCATATCGGCGATTTGACGCCGTGGTCAGCGGCCATCGCAAAATT
ACTTACCGGCGACTAG

Upstream 100 bases:

>100_bases
GAGAATATTTTTCTCCTTACATTGTAATTTAAAGGTCAAATAGCAACAATTTTTTCCGTACTTTTCGCTACTCTTGGCAC
AAAATGATAAATGGATATTA

Downstream 100 bases:

>100_bases
AAACAAAAAAAAGCCAGACTGAATGTCTGGCTTGCTGGAAGAGATCTCTCATTCGGGGGAATAAGGTAGATGCGGATTGT
CCAGCCAATGCGTCAAAAAG

Product: pyridoxal-5'-phosphate-dependent enzyme, beta subunit

Products: NA

Alternate protein names: CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MMSSNWVKNAINEINADHQRSADTHLIRLPLSAFPGIQLYLKDESTHPTGSLKHRLARSLFLYGLCNGWIKEGTPIIEAS
SGSTAISEAWFARLLGLPFIAVMPACTAKRKIEQIQFYGGHCHFVESACEIYAASERLAHELNGHYMDQFTYAERATDWR
GNNNIADSIFRQMRNEPHPVPRFIVMSAGTGGTSATIGRYIRCQGYDTQLMVVDPENSVFLPYWQDRDASLRSPVGSKIE
GIGRPRVEPSFIPDVVDEMLRVPDAASVATAHWLETQLGRKVGASTGTNMWGALQLAARMREAGETGAIVTLLCDSGDRY
LDTYYHPSWVSDHIGDLTPWSAAIAKLLTGD

Sequences:

>Translated_351_residues
MMSSNWVKNAINEINADHQRSADTHLIRLPLSAFPGIQLYLKDESTHPTGSLKHRLARSLFLYGLCNGWIKEGTPIIEAS
SGSTAISEAWFARLLGLPFIAVMPACTAKRKIEQIQFYGGHCHFVESACEIYAASERLAHELNGHYMDQFTYAERATDWR
GNNNIADSIFRQMRNEPHPVPRFIVMSAGTGGTSATIGRYIRCQGYDTQLMVVDPENSVFLPYWQDRDASLRSPVGSKIE
GIGRPRVEPSFIPDVVDEMLRVPDAASVATAHWLETQLGRKVGASTGTNMWGALQLAARMREAGETGAIVTLLCDSGDRY
LDTYYHPSWVSDHIGDLTPWSAAIAKLLTGD
>Mature_351_residues
MMSSNWVKNAINEINADHQRSADTHLIRLPLSAFPGIQLYLKDESTHPTGSLKHRLARSLFLYGLCNGWIKEGTPIIEAS
SGSTAISEAWFARLLGLPFIAVMPACTAKRKIEQIQFYGGHCHFVESACEIYAASERLAHELNGHYMDQFTYAERATDWR
GNNNIADSIFRQMRNEPHPVPRFIVMSAGTGGTSATIGRYIRCQGYDTQLMVVDPENSVFLPYWQDRDASLRSPVGSKIE
GIGRPRVEPSFIPDVVDEMLRVPDAASVATAHWLETQLGRKVGASTGTNMWGALQLAARMREAGETGAIVTLLCDSGDRY
LDTYYHPSWVSDHIGDLTPWSAAIAKLLTGD

Specific function: Two Cysteine Synthase Enzymes Are Found. Both Catalyze The Same Reaction. Cysteine Synthase B Can Also Use Thiosulfate In Place Of Sulfide To Give Cysteine Thiosulfonate As A Product. [C]

COG id: COG0031

COG function: function code E; Cysteine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cysteine synthase/cystathionine beta- synthase family [H]

Homologues:

Organism=Homo sapiens, GI295821202, Length=300, Percent_Identity=25.3333333333333, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI295821200, Length=300, Percent_Identity=25.3333333333333, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4557415, Length=300, Percent_Identity=25.3333333333333, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI2367138, Length=313, Percent_Identity=28.1150159744409, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71996324, Length=355, Percent_Identity=33.2394366197183, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17539800, Length=356, Percent_Identity=30.8988764044944, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17539640, Length=360, Percent_Identity=28.8888888888889, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI17535051, Length=305, Percent_Identity=28.8524590163934, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562970, Length=310, Percent_Identity=28.0645161290323, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32566674, Length=293, Percent_Identity=28.3276450511945, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI115535073, Length=303, Percent_Identity=29.042904290429, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321449, Length=339, Percent_Identity=25.6637168141593, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24643623, Length=321, Percent_Identity=27.1028037383178, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI20129101, Length=321, Percent_Identity=27.1028037383178, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001216
- InterPro:   IPR005856
- InterPro:   IPR005859
- InterPro:   IPR001926
- InterPro:   IPR000634 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =2.5.1.47 [H]

Molecular weight: Translated: 38889; Mature: 38889

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSSNWVKNAINEINADHQRSADTHLIRLPLSAFPGIQLYLKDESTHPTGSLKHRLARSL
CCCCHHHHHHHHHCCCCHHCCCCCEEEEEEHHHCCCEEEEEECCCCCCCHHHHHHHHHHH
FLYGLCNGWIKEGTPIIEASSGSTAISEAWFARLLGLPFIAVMPACTAKRKIEQIQFYGG
HHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHEECC
HCHFVESACEIYAASERLAHELNGHYMDQFTYAERATDWRGNNNIADSIFRQMRNEPHPV
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCC
PRFIVMSAGTGGTSATIGRYIRCQGYDTQLMVVDPENSVFLPYWQDRDASLRSPVGSKIE
CEEEEEECCCCCCHHHHCCEEEECCCCCEEEEECCCCCEEEEEECCCCCCHHCCCCCHHH
GIGRPRVEPSFIPDVVDEMLRVPDAASVATAHWLETQLGRKVGASTGTNMWGALQLAARM
CCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
REAGETGAIVTLLCDSGDRYLDTYYHPSWVSDHIGDLTPWSAAIAKLLTGD
HHCCCCCCEEEEEECCCCCEEECCCCCCHHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MMSSNWVKNAINEINADHQRSADTHLIRLPLSAFPGIQLYLKDESTHPTGSLKHRLARSL
CCCCHHHHHHHHHCCCCHHCCCCCEEEEEEHHHCCCEEEEEECCCCCCCHHHHHHHHHHH
FLYGLCNGWIKEGTPIIEASSGSTAISEAWFARLLGLPFIAVMPACTAKRKIEQIQFYGG
HHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHEECC
HCHFVESACEIYAASERLAHELNGHYMDQFTYAERATDWRGNNNIADSIFRQMRNEPHPV
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCC
PRFIVMSAGTGGTSATIGRYIRCQGYDTQLMVVDPENSVFLPYWQDRDASLRSPVGSKIE
CEEEEEECCCCCCHHHHCCEEEECCCCCEEEEECCCCCEEEEEECCCCCCHHCCCCCHHH
GIGRPRVEPSFIPDVVDEMLRVPDAASVATAHWLETQLGRKVGASTGTNMWGALQLAARM
CCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
REAGETGAIVTLLCDSGDRYLDTYYHPSWVSDHIGDLTPWSAAIAKLLTGD
HHCCCCCCEEEEEECCCCCEEECCCCCCHHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9034314; 10688204 [H]