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The map label for this gene is torA [H]

Identifier: 194737793

GI number: 194737793

Start: 3902601

End: 3905153

Strand: Reverse

Name: torA [H]

Synonym: SeSA_A4033

Alternate gene names: 194737793

Gene position: 3905153-3902601 (Counterclockwise)

Preceding gene: 194737058

Following gene: 194738141

Centisome position: 82.93

GC content: 56.05

Gene sequence:

>2553_bases
ATGAAAAATAAGGACACGCTACACGTCTCTCGTCGACGTTTTCTGGCGCAGCTTGGCGGTTTGACGGTGGCAGGAATGCT
GGGGCCGTCACTGCTGACGCCCCGTAGCGCCCGCGCAGCGGATGCCGCTGCGCCAGGCGCCGCGACGAAAGAGGGTATCC
TTACCGGTTCTCACTGGGGGGCTATTCGCGCCACGGTGGTTGACGGTCGATTTGTGGCGGCAAAACCGTTTGAACAGGAT
AAATACCCGTCCAAAATGATCGCTGGTCTGCCCGATCACGTCCACAACGCGGCGCGTATTCGCTATCCGATGGTGCGCGT
CGACTGGATGCGCAAAGGTCATCAAAGCGACACCTCGCAGCGCGGCGATAATCGTTTTGTGCGCGTCTCCTGGGATGAAG
CGCTGGATCTGTTCTATCAGGAACTGGAGCGGGTGCAAAAAACCTACGGGCCGAGCGCGTTACTGACGGCGAGCGGCTGG
CAATCTACCGGCATGTTCCATAACGCCTCCGGGATGCTGGCGCGCGCGATTGCGCTACATGGCAATAGCGTCAGCACGGG
AGGGGACTATTCGACCGGCGCGGCGCAGGTGATTCTGCCGCGCGTGGTGGGTTCAATGGAAGTGTACGAGCAGCAAACGT
CATGGCCTCTGGTTTTACAGAACAGTAAAACGATTGTGCTATGGGGTTCTGATATGGTGAAAAACCAGCAGGCAAACTGG
TGGTGCCCGGATCACGATGTCTATCAGTACTATGAACAATTAAAAGAGAAGGTTGCCAGCGGCGCTATCTCGGTCATCAG
CATCGACCCGGTCGTCACCTCCACGCACGATTATCTGGGGCGCGATAAGGTCAAACATATCGCCATTAACCCGCAGACGG
ATGTCCCGTTACAACTGGCGCTGGCACATACGCTGTACAGCGAGAAACTGTACGATAAAAATTTCCTCGATAACTACTGC
GTCGGTTTTGACCAGTTCCTCCCCTATTTGCTGGGCGAAAAAGATGGACAGCCCAAAGATGCCGCCTGGGCGGAAAAACT
GTGCGGTATTGACGCCGACACCATCCGCGCGTTGGCGCGGCAGATGGCGGGCGACAGAACGCAAATCATCGCTGGCTGGT
GCGTACAACGTATGCAGCATGGCGAACAGTGGTCATGGATGGTCGTCGTGCTGGCGGCAATGCTGGGACAGATTGGTTTA
CCGGGCGGCGGCTTTGGTTTTGGCTGGCACTACAACGGCGCCGGGACGCCTGGCCGTAAAGGGATCATTTTAAGCGGCTT
TTCCGGTTCGACGACCGTTCCGCCAGTACACGACAGCACGGATTACAAAGGCTACAGCAGCACCATTCCTATTGCACGTT
TTATGGATGCCATTCTTGAACCGGGCAAGGTCATTAACTGGAACGGCAAATCGGTTAAATTACCGCCGCTGAAGATGTGC
GTGTTCGCCGGGACCAACCCGTTCCACCGACACCAACAAATTAACCGCATAATTGAAGGCTGGCGCAAGCTGGAAACGGT
CATCGCTATTGATAACCAGTGGACGTCGACCTGCCGTTTTGCGGATATCGTTTTGCCGGCTACCACCCAATTTGAGCGTA
ACGACCTCGATCAGTTCGGCAACCACTCTAACCGCGGCATTATCGCCATGAAACAGGTGGTGTCGCCGCAGTTTGAAGCG
CGTAACGACTTTGATATTTTCCGCGATCTCTGCCGACGCTTTAACCGTGAAGCGGCATTCACGGAAGGTCTTGATGAAAT
GGGCTGGCTGAAACGCATCTGGCAGGAAGGGAGCCAGCAGGGAAAAGGTCGCGGTATCCACTTACCGACTTTCGAGGTGT
TCTGGAATCAACAGGAGTACATCGAGTTTGATCATCCGCAGATGTTTGTGCGCCATCAGGCTTTCCGTGAAGATCCGGAC
CTGGAGCCGTTGGGCACGCCAAGCGGTTTGATCGAGATTTACTCCAAAACGATCGCCGACATGCAATACGACGATTGTCA
GGGCCATCCCATGTGGTTCGAAAAAATCGAACGCTCGCATGGCGGGCCGGGATCGCAGCGCTGGCCGCTGCACTTACAAT
CCGTCCACCCTGATTTCCGTCTGCATTCCCAACTGTGCGAGTCGGAAGCGCTGCGTCAGCAATATGCCGTTGGCGGCAAG
GAGCCGGTCTTTATTAACCCACAGGATGCCAGCGCGCGCGGGATCCGCAACGGTGACATCGTGCGGGTATTCAATGCACG
CGGGCAGGTACTGGCGGGGGCGGTAGTTTCCGATCGCTATGCGCCGGGCGTGGCGCGAATTCATGAAGGCGCCTGGTACG
ATCCTGATAAAGGCGGCGACATCAATGCGTTGTGTAAGTACGGCAACCCTAACGTATTAACGCTGGATATCGGTACATCA
CAGCTCGCGCAGGCGACCAGCGCGCATACGACGCTGGTGGAAATTGAAAAATATACCGGCCCTATTGATAACGTCACGGC
GTTTAACGGTCCGGTCGAGATGGTCGCGCAGTGTGAATATGTACCCGCATCGCAGGGGAATCCGCATGAATAA

Upstream 100 bases:

>100_bases
ACCAGTCTGGATAAGCGTGAAGAACGTACCTTGTTGAAATATCTCCAGATGAATGCGTCTGATACCACCAATACGCCGCA
CAGCGATAAGGGAGAACACA

Downstream 100 bases:

>100_bases
GCAGCCAGCGCTTGCTCAGGAACAGTACGCCTGCGTATATGCATGGCTGGCGTTACTCTTTTTCCGGGAAGTGGATGATG
AAGGGTTAATACAATTACAG

Product: trimethylamine-N-oxide reductase TorA

Products: NA

Alternate protein names: TMAO reductase; Trimethylamine oxidase [H]

Number of amino acids: Translated: 850; Mature: 850

Protein sequence:

>850_residues
MKNKDTLHVSRRRFLAQLGGLTVAGMLGPSLLTPRSARAADAAAPGAATKEGILTGSHWGAIRATVVDGRFVAAKPFEQD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWMRKGHQSDTSQRGDNRFVRVSWDEALDLFYQELERVQKTYGPSALLTASGW
QSTGMFHNASGMLARAIALHGNSVSTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDMVKNQQANW
WCPDHDVYQYYEQLKEKVASGAISVISIDPVVTSTHDYLGRDKVKHIAINPQTDVPLQLALAHTLYSEKLYDKNFLDNYC
VGFDQFLPYLLGEKDGQPKDAAWAEKLCGIDADTIRALARQMAGDRTQIIAGWCVQRMQHGEQWSWMVVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGIILSGFSGSTTVPPVHDSTDYKGYSSTIPIARFMDAILEPGKVINWNGKSVKLPPLKMC
VFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQFGNHSNRGIIAMKQVVSPQFEA
RNDFDIFRDLCRRFNREAAFTEGLDEMGWLKRIWQEGSQQGKGRGIHLPTFEVFWNQQEYIEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMQYDDCQGHPMWFEKIERSHGGPGSQRWPLHLQSVHPDFRLHSQLCESEALRQQYAVGGK
EPVFINPQDASARGIRNGDIVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGDINALCKYGNPNVLTLDIGTS
QLAQATSAHTTLVEIEKYTGPIDNVTAFNGPVEMVAQCEYVPASQGNPHE

Sequences:

>Translated_850_residues
MKNKDTLHVSRRRFLAQLGGLTVAGMLGPSLLTPRSARAADAAAPGAATKEGILTGSHWGAIRATVVDGRFVAAKPFEQD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWMRKGHQSDTSQRGDNRFVRVSWDEALDLFYQELERVQKTYGPSALLTASGW
QSTGMFHNASGMLARAIALHGNSVSTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDMVKNQQANW
WCPDHDVYQYYEQLKEKVASGAISVISIDPVVTSTHDYLGRDKVKHIAINPQTDVPLQLALAHTLYSEKLYDKNFLDNYC
VGFDQFLPYLLGEKDGQPKDAAWAEKLCGIDADTIRALARQMAGDRTQIIAGWCVQRMQHGEQWSWMVVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGIILSGFSGSTTVPPVHDSTDYKGYSSTIPIARFMDAILEPGKVINWNGKSVKLPPLKMC
VFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQFGNHSNRGIIAMKQVVSPQFEA
RNDFDIFRDLCRRFNREAAFTEGLDEMGWLKRIWQEGSQQGKGRGIHLPTFEVFWNQQEYIEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMQYDDCQGHPMWFEKIERSHGGPGSQRWPLHLQSVHPDFRLHSQLCESEALRQQYAVGGK
EPVFINPQDASARGIRNGDIVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGDINALCKYGNPNVLTLDIGTS
QLAQATSAHTTLVEIEKYTGPIDNVTAFNGPVEMVAQCEYVPASQGNPHE
>Mature_850_residues
MKNKDTLHVSRRRFLAQLGGLTVAGMLGPSLLTPRSARAADAAAPGAATKEGILTGSHWGAIRATVVDGRFVAAKPFEQD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWMRKGHQSDTSQRGDNRFVRVSWDEALDLFYQELERVQKTYGPSALLTASGW
QSTGMFHNASGMLARAIALHGNSVSTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDMVKNQQANW
WCPDHDVYQYYEQLKEKVASGAISVISIDPVVTSTHDYLGRDKVKHIAINPQTDVPLQLALAHTLYSEKLYDKNFLDNYC
VGFDQFLPYLLGEKDGQPKDAAWAEKLCGIDADTIRALARQMAGDRTQIIAGWCVQRMQHGEQWSWMVVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGIILSGFSGSTTVPPVHDSTDYKGYSSTIPIARFMDAILEPGKVINWNGKSVKLPPLKMC
VFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQFGNHSNRGIIAMKQVVSPQFEA
RNDFDIFRDLCRRFNREAAFTEGLDEMGWLKRIWQEGSQQGKGRGIHLPTFEVFWNQQEYIEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMQYDDCQGHPMWFEKIERSHGGPGSQRWPLHLQSVHPDFRLHSQLCESEALRQQYAVGGK
EPVFINPQDASARGIRNGDIVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGDINALCKYGNPNVLTLDIGTS
QLAQATSAHTTLVEIEKYTGPIDNVTAFNGPVEMVAQCEYVPASQGNPHE

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787231, Length=845, Percent_Identity=90.1775147928994, Blast_Score=1591, Evalue=0.0,
Organism=Escherichia coli, GI87081994, Length=831, Percent_Identity=43.5619735258724, Blast_Score=662, Evalue=0.0,
Organism=Escherichia coli, GI145693196, Length=797, Percent_Identity=43.1618569636136, Blast_Score=622, Evalue=1e-179,
Organism=Escherichia coli, GI87081797, Length=862, Percent_Identity=31.0904872389791, Blast_Score=314, Evalue=2e-86,
Organism=Escherichia coli, GI1787870, Length=862, Percent_Identity=28.8863109048724, Blast_Score=269, Evalue=6e-73,
Organism=Escherichia coli, GI171474008, Length=750, Percent_Identity=29.7333333333333, Blast_Score=262, Evalue=6e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311
- InterPro:   IPR011887 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 94654; Mature: 94654

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2 ; PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKDTLHVSRRRFLAQLGGLTVAGMLGPSLLTPRSARAADAAAPGAATKEGILTGSHWG
CCCCCHHHHHHHHHHHHHCCCEEEHHCCCHHCCCCCCCCCCCCCCCCCCCCCCEECCCCC
AIRATVVDGRFVAAKPFEQDKYPSKMIAGLPDHVHNAARIRYPMVRVDWMRKGHQSDTSQ
EEEEEEECCEEEECCCCCCCCCCHHHHHCCCHHHCCHHHEECCCEEEHHHHCCCCCCCCC
RGDNRFVRVSWDEALDLFYQELERVQKTYGPSALLTASGWQSTGMFHNASGMLARAIALH
CCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCHHHHHHHHCC
GNSVSTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDMVKNQQANW
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCHHHCCCCCCC
WCPDHDVYQYYEQLKEKVASGAISVISIDPVVTSTHDYLGRDKVKHIAINPQTDVPLQLA
CCCCCHHHHHHHHHHHHHHCCCEEEEEECCEEECCHHHHCCCCEEEEEECCCCCCCHHHH
LAHTLYSEKLYDKNFLDNYCVGFDQFLPYLLGEKDGQPKDAAWAEKLCGIDADTIRALAR
HHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHH
QMAGDRTQIIAGWCVQRMQHGEQWSWMVVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRK
HHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCC
GIILSGFSGSTTVPPVHDSTDYKGYSSTIPIARFMDAILEPGKVINWNGKSVKLPPLKMC
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCEEECCHHEEE
VFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQFG
EEECCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHC
NHSNRGIIAMKQVVSPQFEARNDFDIFRDLCRRFNREAAFTEGLDEMGWLKRIWQEGSQQ
CCCCCCEEEEHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHCC
GKGRGIHLPTFEVFWNQQEYIEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIAD
CCCCCCCCCCHHEEECCHHHEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
MQYDDCQGHPMWFEKIERSHGGPGSQRWPLHLQSVHPDFRLHSQLCESEALRQQYAVGGK
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
EPVFINPQDASARGIRNGDIVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGD
CCEEECCCCCCCCCCCCCCEEEEECCCCCEEECHHHHCCCCCCHHHHCCCCCCCCCCCCC
INALCKYGNPNVLTLDIGTSQLAQATSAHTTLVEIEKYTGPIDNVTAFNGPVEMVAQCEY
CEEEEECCCCCEEEEECCHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCCHHHHHHHCCC
VPASQGNPHE
CCCCCCCCCC
>Mature Secondary Structure
MKNKDTLHVSRRRFLAQLGGLTVAGMLGPSLLTPRSARAADAAAPGAATKEGILTGSHWG
CCCCCHHHHHHHHHHHHHCCCEEEHHCCCHHCCCCCCCCCCCCCCCCCCCCCCEECCCCC
AIRATVVDGRFVAAKPFEQDKYPSKMIAGLPDHVHNAARIRYPMVRVDWMRKGHQSDTSQ
EEEEEEECCEEEECCCCCCCCCCHHHHHCCCHHHCCHHHEECCCEEEHHHHCCCCCCCCC
RGDNRFVRVSWDEALDLFYQELERVQKTYGPSALLTASGWQSTGMFHNASGMLARAIALH
CCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCHHHHHHHHCC
GNSVSTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDMVKNQQANW
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCHHHCCCCCCC
WCPDHDVYQYYEQLKEKVASGAISVISIDPVVTSTHDYLGRDKVKHIAINPQTDVPLQLA
CCCCCHHHHHHHHHHHHHHCCCEEEEEECCEEECCHHHHCCCCEEEEEECCCCCCCHHHH
LAHTLYSEKLYDKNFLDNYCVGFDQFLPYLLGEKDGQPKDAAWAEKLCGIDADTIRALAR
HHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHH
QMAGDRTQIIAGWCVQRMQHGEQWSWMVVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRK
HHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCC
GIILSGFSGSTTVPPVHDSTDYKGYSSTIPIARFMDAILEPGKVINWNGKSVKLPPLKMC
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCEEECCHHEEE
VFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQFG
EEECCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHC
NHSNRGIIAMKQVVSPQFEARNDFDIFRDLCRRFNREAAFTEGLDEMGWLKRIWQEGSQQ
CCCCCCEEEEHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHCC
GKGRGIHLPTFEVFWNQQEYIEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIAD
CCCCCCCCCCHHEEECCHHHEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
MQYDDCQGHPMWFEKIERSHGGPGSQRWPLHLQSVHPDFRLHSQLCESEALRQQYAVGGK
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
EPVFINPQDASARGIRNGDIVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGD
CCEEECCCCCCCCCCCCCCEEEEECCCCCEEECHHHHCCCCCCHHHHCCCCCCCCCCCCC
INALCKYGNPNVLTLDIGTSQLAQATSAHTTLVEIEKYTGPIDNVTAFNGPVEMVAQCEY
CEEEEECCCCCEEEEECCHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCCHHHHHHHCCC
VPASQGNPHE
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]