| Definition | Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633 chromosome, complete genome. |
|---|---|
| Accession | NC_011094 |
| Length | 4,709,075 |
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The map label for this gene is sopA [H]
Identifier: 194737724
GI number: 194737724
Start: 2121305
End: 2123653
Strand: Direct
Name: sopA [H]
Synonym: SeSA_A2237
Alternate gene names: 194737724
Gene position: 2121305-2123653 (Clockwise)
Preceding gene: 194734860
Following gene: 194735988
Centisome position: 45.05
GC content: 47.0
Gene sequence:
>2349_bases ATGAAAATATCATCAGGCACAATTAATTTTTCTACTATTCCTAACCAGGTTAAAAAATTAATTACCTCTATTCGTGAACA TACGAAAAACGGGCTCGCCTCAAAAATAACCAGTGTTAAAAACACGCATACATCTTTAAATGAAAAATTTAAAACAGGAA AGGACTCACCGATTGAGTTCACGTTACCACAAAAAATAAAAGACTTCTTTCAGCCGAAAGATAAAAACACCTTAAACAAA ACATTGATTACTGTTAAAAATATTAAAGATACAAATAATACAGGTAAGAAAAATATTTCAGAAGAAGATGCCTCAAAAAT GACTGCAGCATTCATGCGTAAGCATATAGCAAATCAATCACGTGATTATAATTACAGAGTGACAGGTGCGGCCCCGCTCC CCGGTGGAGTCTCTGTATCAGCCAATAACAGGCCAACGGTTTCTGAAGGTAGAACACCACCAGTATCCCCCTCCCTCTCA CTTCAGGCTACGTCTTCCCCGTCATCACCTGCCGACTGGGCTAAGAAACTCACGGATGCAGTTTTACGACAGCAAGCCGG AGAACCCCTTACGACCGCAGATCGCGATTTTTCAAACGCAGATTTCCGTAATATTAAATTCAGCAAAATATTGCCCCCCA ACTTCATGAAGCGAGACGGCGATATTATCAAGGGGTTCAACTTTTCAAATTCAAAATTTACTTATTCTGATATATCTCAT TTACATTTTGACGAATGCCGATTCACTTATTCGACACTGAATGATGTAGTCTGCAGTAATACGAAATTTAGTAATTCAGA CATGAATGAAGTGTCTTTACTGTATTCAATTACTACACAACAACAGCCCTCTTTTATTAATACAACCTTAAAAAATACGC TTATACCTCACAAAGCCAACCTCTCCGACGTTATTTTAAATGAACCGGATAATTCATCACCTCCGTCAGTGTCAGGGGGC GGAAATTTTATTCGTCTAGGTGATATCTGGCTGCAAATGCCACTCCTTTGGACTGAGAACGCTGTGGATGGATTTTTAAA TCATGAACATAATAATGGTAAAAGTATTCTGATGACCATTAACAACCTGCCCGATAAATACAGACAGGAAAAAGTCCGGG CAATGGAAGATCTGGTAAAGTCATTTCGGAGTGGCCGCTTAACAGAGGCACGTATCCGGCCAGTTGAAAGCTCGCTGGTG AGCGTACTGGCCCACCCCCCCTATACGCAAAGTGCGCTTATCAGCGAGTGGATCAGGCCTGTTCAGGAACGTTTTTTTGC CCACCAGTGCCAGACCTATAATGACGTTCCCCTGCCGGCTCCTGACACATATTATCAGCAGCGCATACTGCCTGTGTTGC TGGATTCGTTTGACAGGAACAGCGCCGCCATGACCACTCACAGCGGACTCTTTAATCAGGTGATTTTACACTGTATGACA GGCGTGGACTGCACTGATGGCATCCGCCAGAAAGCTGCAGCGCTTTATGAACAGTATCTTGCTCACCCGGCGGTGTCTCC CCACATCCATAATGGGCTCTTCGGCAATTATGACGGCAGCCCGGACTGGACAACCCGCGCTGCAGATAATTTCCTGCTGC TTTCCTCCCAGGATTCAGACACGGCGATGATGCTCTCCACTGACACGCTGTTAACAATGCTAAACCCTACTCCTGACACT GCATGGGACAACTTTTACCTGCTGCGAGCCGGAGAGAACGTTTCCACCGCGCAAATCTCTCCGGTAGAGTTATTCCGTCA TGACTTTCCGGTGTTTCTCGCCGCATTTAATCAGCAGGCCGTGCAGCGACGCTTTGGGGAACTGATTGATATCATCCTCA GCACTGAAGAGCACGGGGAGCTGAACCAGCAGTTTATTGCCGCCACGAACCAGAAACATTCCACCGTGAAGTTGATTGAT GATGCCTCAGTGTCGCGTCTGAACACCATTTTTGACCCCCTGCTTCCTGAAGGCAAACTCAGCCCGGCACACTACCAGCA CATCCTCAGTGCTTATCACCTGACTGACGCCACCCCACAGAAGCAGGCGGAAACCCTGTTCTGTCTCAGTACCGCATTCG CACGCTATTCCTCCAGCGCCATTTTCGGCACTGAGCATGACTCTCCGCCGGCCCTGAGAGGCTATGCGGAGGCGCTGATG CAGAAAGCCTGGGAGCTGTCTCCGGCGATCTTCCCGTCCAGCGAACAGTTTACCGACTGGTCCGACCGTTTTCACGGCCT CCATGGCGCCTTTACCTGTACCAGCGTTGTGGCGGATAGTATGCAACGTCATGCCAGAAAATATTTCCCGAGTGTTCTGT CATCCATCCTGCCACTGGCCTGGGCGTAG
Upstream 100 bases:
>100_bases TGAATTGTGATCTCCATCGCCATACCGACATATGAAACTTACTTCTAAGGCGTTAAAAATCCAGACCGTTTTTCCATAAT GATGTTGATAAGGAATTCTA
Downstream 100 bases:
>100_bases TCCAGCCTTAACCCGTATGGAATTAAGGGACACAGCGTTGTGTCCCTCTGTAAATAGACCCGTTTTAGTCCATGCATTTT TTGAGATCCCGGCCAGATTG
Product: secreted effector protein
Products: NA
Alternate protein names: Salmonella outer protein A; Secreted effector protein SopA [H]
Number of amino acids: Translated: 782; Mature: 782
Protein sequence:
>782_residues MKISSGTINFSTIPNQVKKLITSIREHTKNGLASKITSVKNTHTSLNEKFKTGKDSPIEFTLPQKIKDFFQPKDKNTLNK TLITVKNIKDTNNTGKKNISEEDASKMTAAFMRKHIANQSRDYNYRVTGAAPLPGGVSVSANNRPTVSEGRTPPVSPSLS LQATSSPSSPADWAKKLTDAVLRQQAGEPLTTADRDFSNADFRNIKFSKILPPNFMKRDGDIIKGFNFSNSKFTYSDISH LHFDECRFTYSTLNDVVCSNTKFSNSDMNEVSLLYSITTQQQPSFINTTLKNTLIPHKANLSDVILNEPDNSSPPSVSGG GNFIRLGDIWLQMPLLWTENAVDGFLNHEHNNGKSILMTINNLPDKYRQEKVRAMEDLVKSFRSGRLTEARIRPVESSLV SVLAHPPYTQSALISEWIRPVQERFFAHQCQTYNDVPLPAPDTYYQQRILPVLLDSFDRNSAAMTTHSGLFNQVILHCMT GVDCTDGIRQKAAALYEQYLAHPAVSPHIHNGLFGNYDGSPDWTTRAADNFLLLSSQDSDTAMMLSTDTLLTMLNPTPDT AWDNFYLLRAGENVSTAQISPVELFRHDFPVFLAAFNQQAVQRRFGELIDIILSTEEHGELNQQFIAATNQKHSTVKLID DASVSRLNTIFDPLLPEGKLSPAHYQHILSAYHLTDATPQKQAETLFCLSTAFARYSSSAIFGTEHDSPPALRGYAEALM QKAWELSPAIFPSSEQFTDWSDRFHGLHGAFTCTSVVADSMQRHARKYFPSVLSSILPLAWA
Sequences:
>Translated_782_residues MKISSGTINFSTIPNQVKKLITSIREHTKNGLASKITSVKNTHTSLNEKFKTGKDSPIEFTLPQKIKDFFQPKDKNTLNK TLITVKNIKDTNNTGKKNISEEDASKMTAAFMRKHIANQSRDYNYRVTGAAPLPGGVSVSANNRPTVSEGRTPPVSPSLS LQATSSPSSPADWAKKLTDAVLRQQAGEPLTTADRDFSNADFRNIKFSKILPPNFMKRDGDIIKGFNFSNSKFTYSDISH LHFDECRFTYSTLNDVVCSNTKFSNSDMNEVSLLYSITTQQQPSFINTTLKNTLIPHKANLSDVILNEPDNSSPPSVSGG GNFIRLGDIWLQMPLLWTENAVDGFLNHEHNNGKSILMTINNLPDKYRQEKVRAMEDLVKSFRSGRLTEARIRPVESSLV SVLAHPPYTQSALISEWIRPVQERFFAHQCQTYNDVPLPAPDTYYQQRILPVLLDSFDRNSAAMTTHSGLFNQVILHCMT GVDCTDGIRQKAAALYEQYLAHPAVSPHIHNGLFGNYDGSPDWTTRAADNFLLLSSQDSDTAMMLSTDTLLTMLNPTPDT AWDNFYLLRAGENVSTAQISPVELFRHDFPVFLAAFNQQAVQRRFGELIDIILSTEEHGELNQQFIAATNQKHSTVKLID DASVSRLNTIFDPLLPEGKLSPAHYQHILSAYHLTDATPQKQAETLFCLSTAFARYSSSAIFGTEHDSPPALRGYAEALM QKAWELSPAIFPSSEQFTDWSDRFHGLHGAFTCTSVVADSMQRHARKYFPSVLSSILPLAWA >Mature_782_residues MKISSGTINFSTIPNQVKKLITSIREHTKNGLASKITSVKNTHTSLNEKFKTGKDSPIEFTLPQKIKDFFQPKDKNTLNK TLITVKNIKDTNNTGKKNISEEDASKMTAAFMRKHIANQSRDYNYRVTGAAPLPGGVSVSANNRPTVSEGRTPPVSPSLS LQATSSPSSPADWAKKLTDAVLRQQAGEPLTTADRDFSNADFRNIKFSKILPPNFMKRDGDIIKGFNFSNSKFTYSDISH LHFDECRFTYSTLNDVVCSNTKFSNSDMNEVSLLYSITTQQQPSFINTTLKNTLIPHKANLSDVILNEPDNSSPPSVSGG GNFIRLGDIWLQMPLLWTENAVDGFLNHEHNNGKSILMTINNLPDKYRQEKVRAMEDLVKSFRSGRLTEARIRPVESSLV SVLAHPPYTQSALISEWIRPVQERFFAHQCQTYNDVPLPAPDTYYQQRILPVLLDSFDRNSAAMTTHSGLFNQVILHCMT GVDCTDGIRQKAAALYEQYLAHPAVSPHIHNGLFGNYDGSPDWTTRAADNFLLLSSQDSDTAMMLSTDTLLTMLNPTPDT AWDNFYLLRAGENVSTAQISPVELFRHDFPVFLAAFNQQAVQRRFGELIDIILSTEEHGELNQQFIAATNQKHSTVKLID DASVSRLNTIFDPLLPEGKLSPAHYQHILSAYHLTDATPQKQAETLFCLSTAFARYSSSAIFGTEHDSPPALRGYAEALM QKAWELSPAIFPSSEQFTDWSDRFHGLHGAFTCTSVVADSMQRHARKYFPSVLSSILPLAWA
Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway [H]
COG id: COG1357
COG function: function code S; Uncharacterized low-complexity proteins
Gene ontology:
Cell location: Secreted. Host cell (By similarity). Note=Secreted via type III secretion system 1 (SPI-1 TTSS), and delivered into the host cell (By similarity) [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the SopA E3 ligase family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
NA
Pfam domain/function: NA
EC number: NA
Molecular weight: Translated: 87275; Mature: 87275
Theoretical pI: Translated: 7.29; Mature: 7.29
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKISSGTINFSTIPNQVKKLITSIREHTKNGLASKITSVKNTHTSLNEKFKTGKDSPIEF CCCCCCCEEHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE TLPQKIKDFFQPKDKNTLNKTLITVKNIKDTNNTGKKNISEEDASKMTAAFMRKHIANQS ECHHHHHHHHCCCCCCCHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC RDYNYRVTGAAPLPGGVSVSANNRPTVSEGRTPPVSPSLSLQATSSPSSPADWAKKLTDA CCCCEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHH VLRQQAGEPLTTADRDFSNADFRNIKFSKILPPNFMKRDGDIIKGFNFSNSKFTYSDISH HHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHCCCCEEECCCCCCCEEEHHHHCH LHFDECRFTYSTLNDVVCSNTKFSNSDMNEVSLLYSITTQQQPSFINTTLKNTLIPHKAN HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEEECCCCCCCHHHHHHHHCCCCCCCC LSDVILNEPDNSSPPSVSGGGNFIRLGDIWLQMPLLWTENAVDGFLNHEHNNGKSILMTI CCHHEECCCCCCCCCCCCCCCCEEEECHHHHHCCHHCCCHHHHHHHCCCCCCCCEEEEEE NNLPDKYRQEKVRAMEDLVKSFRSGRLTEARIRPVESSLVSVLAHPPYTQSALISEWIRP CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH VQERFFAHQCQTYNDVPLPAPDTYYQQRILPVLLDSFDRNSAAMTTHSGLFNQVILHCMT HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHC GVDCTDGIRQKAAALYEQYLAHPAVSPHIHNGLFGNYDGSPDWTTRAADNFLLLSSQDSD CCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCHHCCCCEEEEECCCCC TAMMLSTDTLLTMLNPTPDTAWDNFYLLRAGENVSTAQISPVELFRHDFPVFLAAFNQQA CEEEEECCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHHH VQRRFGELIDIILSTEEHGELNQQFIAATNQKHSTVKLIDDASVSRLNTIFDPLLPEGKL HHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCC SPAHYQHILSAYHLTDATPQKQAETLFCLSTAFARYSSSAIFGTEHDSPPALRGYAEALM CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHH QKAWELSPAIFPSSEQFTDWSDRFHGLHGAFTCTSVVADSMQRHARKYFPSVLSSILPLA HHHHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC WA CC >Mature Secondary Structure MKISSGTINFSTIPNQVKKLITSIREHTKNGLASKITSVKNTHTSLNEKFKTGKDSPIEF CCCCCCCEEHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE TLPQKIKDFFQPKDKNTLNKTLITVKNIKDTNNTGKKNISEEDASKMTAAFMRKHIANQS ECHHHHHHHHCCCCCCCHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC RDYNYRVTGAAPLPGGVSVSANNRPTVSEGRTPPVSPSLSLQATSSPSSPADWAKKLTDA CCCCEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHH VLRQQAGEPLTTADRDFSNADFRNIKFSKILPPNFMKRDGDIIKGFNFSNSKFTYSDISH HHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHCCCCEEECCCCCCCEEEHHHHCH LHFDECRFTYSTLNDVVCSNTKFSNSDMNEVSLLYSITTQQQPSFINTTLKNTLIPHKAN HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEEECCCCCCCHHHHHHHHCCCCCCCC LSDVILNEPDNSSPPSVSGGGNFIRLGDIWLQMPLLWTENAVDGFLNHEHNNGKSILMTI CCHHEECCCCCCCCCCCCCCCCEEEECHHHHHCCHHCCCHHHHHHHCCCCCCCCEEEEEE NNLPDKYRQEKVRAMEDLVKSFRSGRLTEARIRPVESSLVSVLAHPPYTQSALISEWIRP CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH VQERFFAHQCQTYNDVPLPAPDTYYQQRILPVLLDSFDRNSAAMTTHSGLFNQVILHCMT HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHC GVDCTDGIRQKAAALYEQYLAHPAVSPHIHNGLFGNYDGSPDWTTRAADNFLLLSSQDSD CCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCHHCCCCEEEEECCCCC TAMMLSTDTLLTMLNPTPDTAWDNFYLLRAGENVSTAQISPVELFRHDFPVFLAAFNQQA CEEEEECCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHHH VQRRFGELIDIILSTEEHGELNQQFIAATNQKHSTVKLIDDASVSRLNTIFDPLLPEGKL HHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCC SPAHYQHILSAYHLTDATPQKQAETLFCLSTAFARYSSSAIFGTEHDSPPALRGYAEALM CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHH QKAWELSPAIFPSSEQFTDWSDRFHGLHGAFTCTSVVADSMQRHARKYFPSVLSSILPLA HHHHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC WA CC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA