Click here to switch to the map view.

The map label for this gene is yihQ [H]

Identifier: 194737357

GI number: 194737357

Start: 4107002

End: 4109038

Strand: Reverse

Name: yihQ [H]

Synonym: SeSA_A4229

Alternate gene names: 194737357

Gene position: 4109038-4107002 (Counterclockwise)

Preceding gene: 194737983

Following gene: 194735020

Centisome position: 87.26

GC content: 55.42

Gene sequence:

>2037_bases
ATGAATTCTCTACCACAACGGTCAACCGATTTTGAACTGACAACATCACAGGATGGTTTTGCACTTAGCTGGCAGCAGCG
CCTGATTTTACGCCACAGCGCCGAAACCCCCTGTCTGTGGATTGGCGCGGGCGTTGCCGACATTGATATGTTTCGCGGCA
ACTTTAGTATCAAAGACAAACTTAACGAGAAGATTGCATTAACGGAGGCCACGGTCAGCGAGCTACCCGACGGCTGGCTG
GTACAATTCAGCCGTGGCGCAACAATTAGCGCCACCCTTCGCATCTCCGCCGATGAGGCGGGACGCCTGACGTTGGATCT
GCAAAACGACGACCTGCACCATAACCGTATCTGGTTACGCCTCGCAGCTAATCCAGACGACCATATCTACGGCTGCGGCG
AACAGTTCTCTTATTTCGATTTGCGCGGCAAGCCGTTCCCGCTGTGGACCAGCGAACAGGGCGTTGGCCGTAATAAAACC
AGCTATGTCACCTGGCAGGCAGACTGCAAAGAGAACGCCGGCGGCGACTATTACTGGACCTTCTTCCCGCAACCGACCTT
TGTCAGCACGCAAAAATACTACTGCCACGTTGAAAATAGCTGTTATATGAATTTCGACTTCAGCGCGCCGGAGTATCACG
AACTGGCGCTGTGGGAAGATAAAACTACGCTGCGTTTTGAGTGTGCCGACACCTACATCGCCCTGCTGGAAAAACTGACT
GCGCTGTTAGGCCGCCAGCCGGAGCTGCCGGACTGGGTTTACGACGGCGTCACGTTAGGCATTCAGGGCGGTACGGAAGT
TTGCCAGAAAAAACTGGATACCATGCGCAACGCTGGCGTAAAAGTGAACGGTATTTGGGCGCAGGACTGGTCCGGTATCC
GCATGACCTCCTTTGGCAAGCGCGTGATGTGGAACTGGAAGTGGAATAGCGACAACTATCCGCAACTGGATAGCCGGATC
AAACAGTGGAAAGAAGAAGGCGTCCAGTTCCTCTCTTATATCAATCCATACGTCGCCAGTGATAAAGACCTCTGCGCCGA
GGCGGCGAAACACGGCTATCTGGCGAAAGACGCCACGGGCGGCGACTATCTGGTCGAGTTTGGCGAATTCTATGGCGGCG
TGGTCGATCTGACCAATCCTGAAGCTTACGACTGGTTCAAAGACGTCATCAAAAAGAACATGATCGCGCTCGGCTGCAGC
GGCTGGATGGCGGATTTCGGCGAATATCTGCCGACCGACACGTATCTGCACAACGGCGTCAGCGCCGAGATCATGCATAA
CGCCTGGCCTGCGCTGTGGGCGAAATGTAACTACGAAGCGCTACAGGAGACCGGCAAACTCGGCGAGATCCTGTTCTTTA
TGCGTGCGGGTTACACCGGTAGCCAGAAGTATTCCACCATGATGTGGGCAGGTGACCAGAACGTTGACTGGAGCCTTGAT
GATGGTCTGGCCTCGGTAGTACCTGCGGCATTGTCGCTGGCGATGACCGGCCATGGTCTGCATCACAGCGATATCGGCGG
CTACACCACCCTGTTTGACATGAAACGCAGCAAAGAGTTGCTGCTGCGCTGGTGCGATTTCAGCGCCTTTACGCCGATGA
TGCGCACCCATGAAGGCAACCGCCCCGGCGATAACTGGCAGTTCGACGGCGACGCGGAAACTATTGCCCACTTTGCCCGC
ATGACCACCGTCTTTACCACGCTGAAACCGTATCTCAAGCAGGCGGTGGCGCAAAACGCGGCTACCGGTCTGCCGGTCAT
GCGTCCGCTATTCCTGCACTACGAGAACGATGCCGCAACCTACGCCCTGAAATATCAATATCTGCTCGGTCAGGATCTGC
TGGTCGCGCCGGTTTATGAGCAGGGGCGTTGCGATTGGACGCTGTACCTGCCGGAAGATCACTGGGTGAATATCTGGACC
GGCGAAGCTCACCACGGCGGTGAAATTACCGTGGATGCGCCCATTGGCAAGCCGCCGGTCTTCTATCGCGCGAAGAGCGA
GTGGGCTTCACTTTTTGCTTCTTTACGGAATATCTAA

Upstream 100 bases:

>100_bases
ATTCATCTTGCCCCAAAAGCGATCCATCAACTGCATTTTTCCATCGGCTGCGACTAGCCCAAATGGATTACCGAATTACC
CTACATTCACGGAGATTACA

Downstream 100 bases:

>100_bases
TACGGCTCGCCCGCAGGGAAACCTGCGGGCAGATGGAGAAGAATAATGAGTCAAACATCATCGAATCCGGCAACCCTACG
CTTGCCGTTTAAAGAAAAAC

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MNSLPQRSTDFELTTSQDGFALSWQQRLILRHSAETPCLWIGAGVADIDMFRGNFSIKDKLNEKIALTEATVSELPDGWL
VQFSRGATISATLRISADEAGRLTLDLQNDDLHHNRIWLRLAANPDDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKT
SYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVENSCYMNFDFSAPEYHELALWEDKTTLRFECADTYIALLEKLT
ALLGRQPELPDWVYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSDNYPQLDSRI
KQWKEEGVQFLSYINPYVASDKDLCAEAAKHGYLAKDATGGDYLVEFGEFYGGVVDLTNPEAYDWFKDVIKKNMIALGCS
GWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALQETGKLGEILFFMRAGYTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFDMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTTVFTTLKPYLKQAVAQNAATGLPVMRPLFLHYENDAATYALKYQYLLGQDLLVAPVYEQGRCDWTLYLPEDHWVNIWT
GEAHHGGEITVDAPIGKPPVFYRAKSEWASLFASLRNI

Sequences:

>Translated_678_residues
MNSLPQRSTDFELTTSQDGFALSWQQRLILRHSAETPCLWIGAGVADIDMFRGNFSIKDKLNEKIALTEATVSELPDGWL
VQFSRGATISATLRISADEAGRLTLDLQNDDLHHNRIWLRLAANPDDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKT
SYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVENSCYMNFDFSAPEYHELALWEDKTTLRFECADTYIALLEKLT
ALLGRQPELPDWVYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSDNYPQLDSRI
KQWKEEGVQFLSYINPYVASDKDLCAEAAKHGYLAKDATGGDYLVEFGEFYGGVVDLTNPEAYDWFKDVIKKNMIALGCS
GWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALQETGKLGEILFFMRAGYTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFDMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTTVFTTLKPYLKQAVAQNAATGLPVMRPLFLHYENDAATYALKYQYLLGQDLLVAPVYEQGRCDWTLYLPEDHWVNIWT
GEAHHGGEITVDAPIGKPPVFYRAKSEWASLFASLRNI
>Mature_678_residues
MNSLPQRSTDFELTTSQDGFALSWQQRLILRHSAETPCLWIGAGVADIDMFRGNFSIKDKLNEKIALTEATVSELPDGWL
VQFSRGATISATLRISADEAGRLTLDLQNDDLHHNRIWLRLAANPDDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKT
SYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVENSCYMNFDFSAPEYHELALWEDKTTLRFECADTYIALLEKLT
ALLGRQPELPDWVYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSDNYPQLDSRI
KQWKEEGVQFLSYINPYVASDKDLCAEAAKHGYLAKDATGGDYLVEFGEFYGGVVDLTNPEAYDWFKDVIKKNMIALGCS
GWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALQETGKLGEILFFMRAGYTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFDMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTTVFTTLKPYLKQAVAQNAATGLPVMRPLFLHYENDAATYALKYQYLLGQDLLVAPVYEQGRCDWTLYLPEDHWVNIWT
GEAHHGGEITVDAPIGKPPVFYRAKSEWASLFASLRNI

Specific function: Exhibits hydrolysis activity against alpha-glucosyl fluoride, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed [H]

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI153791946, Length=340, Percent_Identity=25.5882352941176, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI88900491, Length=387, Percent_Identity=25.5813953488372, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI38202257, Length=387, Percent_Identity=25.5813953488372, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI66346737, Length=398, Percent_Identity=25.8793969849246, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI119393895, Length=450, Percent_Identity=22.4444444444444, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI119393893, Length=450, Percent_Identity=22.4444444444444, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI119393891, Length=450, Percent_Identity=22.4444444444444, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI310115361, Length=257, Percent_Identity=28.0155642023346, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI221316699, Length=257, Percent_Identity=28.0155642023346, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI2367323, Length=678, Percent_Identity=87.4631268436578, Blast_Score=1263, Evalue=0.0,
Organism=Escherichia coli, GI2367256, Length=549, Percent_Identity=23.6794171220401, Blast_Score=172, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI17560800, Length=380, Percent_Identity=23.6842105263158, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17560798, Length=380, Percent_Identity=23.6842105263158, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71991189, Length=343, Percent_Identity=25.6559766763848, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32563849, Length=231, Percent_Identity=30.7359307359307, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71985706, Length=237, Percent_Identity=30.379746835443, Blast_Score=85, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319706, Length=381, Percent_Identity=22.0472440944882, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24650054, Length=364, Percent_Identity=23.6263736263736, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24643749, Length=400, Percent_Identity=25, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24643753, Length=400, Percent_Identity=25, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24643751, Length=400, Percent_Identity=25, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24643746, Length=400, Percent_Identity=25, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21357605, Length=400, Percent_Identity=25, Blast_Score=90, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 76966; Mature: 76966

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLPQRSTDFELTTSQDGFALSWQQRLILRHSAETPCLWIGAGVADIDMFRGNFSIKDK
CCCCCCCCCCEEEEECCCCEEEHHHHHHHHHCCCCCCEEEEECCHHEEEEECCCCEEHHH
LNEKIALTEATVSELPDGWLVQFSRGATISATLRISADEAGRLTLDLQNDDLHHNRIWLR
CCCEEEEEHHHHHHCCCCEEEEEECCCEEEEEEEEECCCCCEEEEEECCCCCCCCEEEEE
LAANPDDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKTSYVTWQADCKENAGGDYYWT
EECCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEE
FFPQPTFVSTQKYYCHVENSCYMNFDFSAPEYHELALWEDKTTLRFECADTYIALLEKLT
ECCCCCEEECCEEEEEECCCEEEEECCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHH
ALLGRQPELPDWVYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGK
HHHCCCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCEEECCCC
RVMWNWKWNSDNYPQLDSRIKQWKEEGVQFLSYINPYVASDKDLCAEAAKHGYLAKDATG
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHCCCEEECCCC
GDYLVEFGEFYGGVVDLTNPEAYDWFKDVIKKNMIALGCSGWMADFGEYLPTDTYLHNGV
CHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCCHHHHCCC
SAEIMHNAWPALWAKCNYEALQETGKLGEILFFMRAGYTGSQKYSTMMWAGDQNVDWSLD
CHHHHHCCCHHHHHCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCC
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFDMKRSKELLLRWCDFSAFTPMMRTHEGN
CCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHCCCHHHHCCCC
RPGDNWQFDGDAETIAHFARMTTVFTTLKPYLKQAVAQNAATGLPVMRPLFLHYENDAAT
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCEEEEEECCCCEE
YALKYQYLLGQDLLVAPVYEQGRCDWTLYLPEDHWVNIWTGEAHHGGEITVDAPIGKPPV
EEEEEEECCCCCEEEEECCCCCCCCEEEECCCCCEEEEEECCCCCCCEEEEECCCCCCCE
FYRAKSEWASLFASLRNI
EEECHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSLPQRSTDFELTTSQDGFALSWQQRLILRHSAETPCLWIGAGVADIDMFRGNFSIKDK
CCCCCCCCCCEEEEECCCCEEEHHHHHHHHHCCCCCCEEEEECCHHEEEEECCCCEEHHH
LNEKIALTEATVSELPDGWLVQFSRGATISATLRISADEAGRLTLDLQNDDLHHNRIWLR
CCCEEEEEHHHHHHCCCCEEEEEECCCEEEEEEEEECCCCCEEEEEECCCCCCCCEEEEE
LAANPDDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKTSYVTWQADCKENAGGDYYWT
EECCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEE
FFPQPTFVSTQKYYCHVENSCYMNFDFSAPEYHELALWEDKTTLRFECADTYIALLEKLT
ECCCCCEEECCEEEEEECCCEEEEECCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHH
ALLGRQPELPDWVYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGK
HHHCCCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCEEECCCC
RVMWNWKWNSDNYPQLDSRIKQWKEEGVQFLSYINPYVASDKDLCAEAAKHGYLAKDATG
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHCCCEEECCCC
GDYLVEFGEFYGGVVDLTNPEAYDWFKDVIKKNMIALGCSGWMADFGEYLPTDTYLHNGV
CHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCCHHHHCCC
SAEIMHNAWPALWAKCNYEALQETGKLGEILFFMRAGYTGSQKYSTMMWAGDQNVDWSLD
CHHHHHCCCHHHHHCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCC
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFDMKRSKELLLRWCDFSAFTPMMRTHEGN
CCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHCCCHHHHCCCC
RPGDNWQFDGDAETIAHFARMTTVFTTLKPYLKQAVAQNAATGLPVMRPLFLHYENDAAT
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCEEEEEECCCCEE
YALKYQYLLGQDLLVAPVYEQGRCDWTLYLPEDHWVNIWTGEAHHGGEITVDAPIGKPPV
EEEEEEECCCCCEEEEECCCCCCCCEEEECCCCCEEEEEECCCCCCCEEEEECCCCCCCE
FYRAKSEWASLFASLRNI
EEECHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503 [H]