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The map label for this gene is pheC [H]

Identifier: 194737334

GI number: 194737334

Start: 689969

End: 690739

Strand: Reverse

Name: pheC [H]

Synonym: SeSA_A0714

Alternate gene names: 194737334

Gene position: 690739-689969 (Counterclockwise)

Preceding gene: 194736810

Following gene: 194737548

Centisome position: 14.67

GC content: 42.28

Gene sequence:

>771_bases
ATGAAAAAAGTATATTTTATGTTTGTTATCTTGTTGTCACTTTCAGGTATTCATTCCGCGATGGCAAAACCCTGGCAGGA
GATTAAAGAAAGCAAAGAGTTACGTGTGGGGGTGCCTAGTGACTATGCTCCCCTCGCATTTCACAACAGACAAAATAAAT
TAATCGGTTTTGATATTGATATGGCATATTCACTGGGCAAAGCTCTGCACCTGAATATCCTGTTTGTACCTAGCAGTTGG
CCTACGCTGTCAACTGACCTGGCAGCAGACAAATTTGATATTGCAATGGGAGGGATTACAGAAACTCCCGGCAGAAGAAA
ACAGTTCGCACTTTCTTCTCCGGTACTTAAAAATGGGAAAATAGCGCTGACGCAATGTAACAGGATTAATGACTTCAAAT
CTCTTGAAGATATTGACCGTAAGGGCGTGCGGATTGTTGTTAATCCAGGTGGTACAAATCAGGACTATGTTGACAAGCAT
ATCAGGTATGCAGATGTTATTCGCGAAAAAGATAATGATGCCACTCTGCAGAGGATTCGTGAACGCAGCGCTGATGTCAT
GTTTACCGACTTGCTCGAAGGTAATTATTACCAGAACAAAGAGCCAGGTGTCTTCTGCGTATCAACCAGGAGTATCCTCC
CCGACACTGCCGGTAATAAAGTCTATATGATGGCGAAGGATAATCAGTATCTTCTTGACGCTGTAAATAGCTGGTTATCT
GATGAAAACAGAATCATACTTGCCAGAAAGTGGCAGATAAATCCAGAGTAG

Upstream 100 bases:

>100_bases
ACCACTATTATTGGATTCCCTGTCCGGTAAAGGTTACCGGCGCAATGGAGAGAAGACAATCTCATCTGTAGTCTACTGAT
CAAACATTAGGGTAAGAGTA

Downstream 100 bases:

>100_bases
CCGCCACAAAGTTTTGACAAGCACCATTGCCGACTGACGAACAGAACTGGCGCGGGGTGAAAGATGTGACGATGATAAAG
CCAGCCAGGCTAAATGGATG

Product: polar amino acid ABC transporter periplasmic amino acid-binding protein

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKKVYFMFVILLSLSGIHSAMAKPWQEIKESKELRVGVPSDYAPLAFHNRQNKLIGFDIDMAYSLGKALHLNILFVPSSW
PTLSTDLAADKFDIAMGGITETPGRRKQFALSSPVLKNGKIALTQCNRINDFKSLEDIDRKGVRIVVNPGGTNQDYVDKH
IRYADVIREKDNDATLQRIRERSADVMFTDLLEGNYYQNKEPGVFCVSTRSILPDTAGNKVYMMAKDNQYLLDAVNSWLS
DENRIILARKWQINPE

Sequences:

>Translated_256_residues
MKKVYFMFVILLSLSGIHSAMAKPWQEIKESKELRVGVPSDYAPLAFHNRQNKLIGFDIDMAYSLGKALHLNILFVPSSW
PTLSTDLAADKFDIAMGGITETPGRRKQFALSSPVLKNGKIALTQCNRINDFKSLEDIDRKGVRIVVNPGGTNQDYVDKH
IRYADVIREKDNDATLQRIRERSADVMFTDLLEGNYYQNKEPGVFCVSTRSILPDTAGNKVYMMAKDNQYLLDAVNSWLS
DENRIILARKWQINPE
>Mature_256_residues
MKKVYFMFVILLSLSGIHSAMAKPWQEIKESKELRVGVPSDYAPLAFHNRQNKLIGFDIDMAYSLGKALHLNILFVPSSW
PTLSTDLAADKFDIAMGGITETPGRRKQFALSSPVLKNGKIALTQCNRINDFKSLEDIDRKGVRIVVNPGGTNQDYVDKH
IRYADVIREKDNDATLQRIRERSADVMFTDLLEGNYYQNKEPGVFCVSTRSILPDTAGNKVYMMAKDNQYLLDAVNSWLS
DENRIILARKWQINPE

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=229, Percent_Identity=24.4541484716157, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787085, Length=212, Percent_Identity=25, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787031, Length=182, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 29077; Mature: 29077

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVYFMFVILLSLSGIHSAMAKPWQEIKESKELRVGVPSDYAPLAFHNRQNKLIGFDID
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEECCCCCEEEEEHH
MAYSLGKALHLNILFVPSSWPTLSTDLAADKFDIAMGGITETPGRRKQFALSSPVLKNGK
HHHHCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCC
IALTQCNRINDFKSLEDIDRKGVRIVVNPGGTNQDYVDKHIRYADVIREKDNDATLQRIR
EEEEECCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
ERSADVMFTDLLEGNYYQNKEPGVFCVSTRSILPDTAGNKVYMMAKDNQYLLDAVNSWLS
HHCCCEEEEEHHCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHC
DENRIILARKWQINPE
CCCEEEEEEEECCCCC
>Mature Secondary Structure
MKKVYFMFVILLSLSGIHSAMAKPWQEIKESKELRVGVPSDYAPLAFHNRQNKLIGFDID
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEECCCCCEEEEEHH
MAYSLGKALHLNILFVPSSWPTLSTDLAADKFDIAMGGITETPGRRKQFALSSPVLKNGK
HHHHCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCC
IALTQCNRINDFKSLEDIDRKGVRIVVNPGGTNQDYVDKHIRYADVIREKDNDATLQRIR
EEEEECCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
ERSADVMFTDLLEGNYYQNKEPGVFCVSTRSILPDTAGNKVYMMAKDNQYLLDAVNSWLS
HHCCCEEEEEHHCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHC
DENRIILARKWQINPE
CCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]