Click here to switch to the map view.

The map label for this gene is plsB [H]

Identifier: 194737294

GI number: 194737294

Start: 4306689

End: 4309109

Strand: Reverse

Name: plsB [H]

Synonym: SeSA_A4427

Alternate gene names: 194737294

Gene position: 4309109-4306689 (Counterclockwise)

Preceding gene: 194734694

Following gene: 194737658

Centisome position: 91.51

GC content: 54.69

Gene sequence:

>2421_bases
ATGTCCGGCTGGCCACGAATTTACTACAAATTACTGAATTTACCATTAAGCATACTGGTAAAAAGCAAGTCTATTCCGGC
GGAACCCGCCCAGGAATTGGGGCTCGATACTTCTCGCCCCATTATGTATGTCTTGCCATACAACTCAAAAGCGGACTTAC
TGACGCTGCGGGCTCAATGTCTGGCGCACGATCTCCCGGATCCGCTGGAGCCGCTGGAGATCGACGGCGCGCTGTTGCCA
CGCTATGTATTTATTCACGGCGGACCGCGTGTCTTTACCTATTACACGCCAAAAGAAGAGTCGGTGAAACTTTTTCACGA
TTATCTCGATCTGCATCGGAGTAATCCGGCTTTGGACGTGCAGATGGTGCCCGTTTCCGTGATGTTTGGCCGCGCGCCGG
GTCGTGAAAAGGGAGAAGATAACCCGCCTTTACGTATGCTGAACGGCGTACAGAAATTCTTTGCCATCTCCTGGCTGGGT
CGCGATAGCTTTGTCCGATTCTCGCCGTCCGTCTCATTGCGTCGTATGGCTGATGAACACGGCACCGATAAAATCATCGC
GCAGAAGCTGGCTCGCGTGGCGCGTATGCACTTTGCTCGCCAGCGCCTGGCGGCGGTTGGCCCACGCCTGCCCGCTCGTC
AGGATCTGTTTAACAAACTGCTGGCCTCGAAAGTGATCGCTCGCGCGGTAGAAGACGAAGCGCGCAGTAAGAAAATCTCT
CATGAAAAAGCGCAGCAAAACGCCATTGCGCTGATGGAAGAGATCGCGGCGAACTTCTCTTACGAGATGATTCGTTTGAC
CGACAGGATTTTGGGGTTTACCTGGAACCGACTGTACCAGGGGATTAACGTGCATAACGCCGAGCGCGTACGCCAACTGG
CGCACGACGGGCATGAAATCGTCTATGTACCCTGTCACCGCAGCCATATGGACTATTTGCTCCTTTCTTATGTGCTGTAC
CATCAGGGACTGGTTCCGCCGCACATTGCCGCCGGTATTAACCTTAATTTCTGGCCCGCTGGCCCAATTTTCCGTCGTCT
GGGCGCGTTCTTTATTCGTCGCACCTTTAAGGGGAATAAACTCTATTCCACCGTCTTTCGCGAATACCTGGGCGAGCTGT
TCAGCCGCGGCTACTCGGTTGAGTATTTTGTCGAAGGAGGACGTTCGCGTACCGGACGTTTGTTAGATCCGAAAACCGGC
ACCCTGTCGATGACTATCCAGGCGATGCTGCGCGGCGGTACCCGTCCAATTACGTTAGTGCCTATTTACATCGGCTATGA
GCACGTCATGGAAGTGGGCACCTATGCGAAAGAACTGCGCGGCGCGACAAAAGAGAAAGAGAGCCTGCCGCAGATGCTGA
AAGGCTTGAGCAAGCTGCGCAATCTGGGTCAGGGCTACGTTAACTTTGGCGAACCGATGCCGCTCATGACGTACCTGAAC
CAGCATGTGCCGGAGTGGCGCGAATCTATAGACCCTATAGAGGCCATACGCCCAGCCTGGCTGACGCCGACGGTAAATAG
TATCGCCGCCGATCTGATGGTGCGTATTAACAACGCTGGCGCGGCAAACGCGATGAACCTGTGTTGTACCGCGCTGTTAG
CGTCGCGTCAGCGCTCGCTCACCCGCGAGCAGCTCACCGAGCAGCTTGATTGCTATCTCGATCTGATGCGCAATGTCCCT
TATTCCACAGACTCAACCGTTCCTGCCGCCAGCGCTGGCGAGCTCATCGCTCACGCGCTGCAGATGAATAAGTTTGAGGT
CGAGAAAGACACCATTGGCGATATCATCATTCTGCCGCGCGAGCAGGCGGTGTTGATGACCTACTATCGTAACAATATCG
CGCATATGTTGATTATGCCTTCGCTGATGGCGGCGATTATCACCCAGCATCGTCGCATTTCGCGTGATGCGTTGCAGCAG
CATGTTGAAGCGCTCTATCCGATGTTAAAAGCGGAGCTGTTCCTGCGCTGGGAGCGCGAGGAGTTAGCCTCGGTCATTGA
CGCTCTGGCCAGTGAAATGCAGCGTCAGGGGCTAATCACCCTGCAGGATGATGAACTGCATATCAACCCGGCGCATTCCC
GTACGCTGCAGCTGCTGGCGGCAGGCGCGCGTGAAACGCTACAGCGTTATGCCATTACGTTCTGGCTGTTGAGCGCCAAT
CCGTCCATCAACCGCAGTACGCTGGAGAAAGAAAGCCGTACCGTGGCGCAACGTCTGTCTGTCCTGCACGGTATTAACGC
GCCGGAGTTTTTCGACAAAGCGGTGTTCAGTTCACTCGTGTTGACGCTACGGGATGAGGGTTATATCAGTGATACGGGCG
ATGCCGAACCGGCAGAAACGATGAAGATATATCAGATGCTTGCCGATCTGATTACCTCTGATGTCCGTCTGACGATTGAA
AGCGCGACGCAGGGCGAGTAA

Upstream 100 bases:

>100_bases
AACGCAGCGCGAAGTATGACGGGATACAACAGAAATTCGCTAAACTTTCTGATATCCTTGCACCGCATTTGCATTATTAA
CCAGAGGCTTTACATCGTTT

Downstream 100 bases:

>100_bases
GCCAGTGCCTGAAATGCCCGATGGCGTAAGCTTATCGGGCAACTGATATGACGTATTGAAAATTTTGGCTTTGTAGGCCG
GGTCCGCCCGGCATGACATC

Product: glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: GPAT [H]

Number of amino acids: Translated: 806; Mature: 805

Protein sequence:

>806_residues
MSGWPRIYYKLLNLPLSILVKSKSIPAEPAQELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGALLP
RYVFIHGGPRVFTYYTPKEESVKLFHDYLDLHRSNPALDVQMVPVSVMFGRAPGREKGEDNPPLRMLNGVQKFFAISWLG
RDSFVRFSPSVSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKVIARAVEDEARSKKIS
HEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHEIVYVPCHRSHMDYLLLSYVLY
HQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTG
TLSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLKGLSKLRNLGQGYVNFGEPMPLMTYLN
QHVPEWRESIDPIEAIRPAWLTPTVNSIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLDCYLDLMRNVP
YSTDSTVPAASAGELIAHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLIMPSLMAAIITQHRRISRDALQQ
HVEALYPMLKAELFLRWEREELASVIDALASEMQRQGLITLQDDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSAN
PSINRSTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDTGDAEPAETMKIYQMLADLITSDVRLTIE
SATQGE

Sequences:

>Translated_806_residues
MSGWPRIYYKLLNLPLSILVKSKSIPAEPAQELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGALLP
RYVFIHGGPRVFTYYTPKEESVKLFHDYLDLHRSNPALDVQMVPVSVMFGRAPGREKGEDNPPLRMLNGVQKFFAISWLG
RDSFVRFSPSVSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKVIARAVEDEARSKKIS
HEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHEIVYVPCHRSHMDYLLLSYVLY
HQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTG
TLSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLKGLSKLRNLGQGYVNFGEPMPLMTYLN
QHVPEWRESIDPIEAIRPAWLTPTVNSIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLDCYLDLMRNVP
YSTDSTVPAASAGELIAHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLIMPSLMAAIITQHRRISRDALQQ
HVEALYPMLKAELFLRWEREELASVIDALASEMQRQGLITLQDDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSAN
PSINRSTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDTGDAEPAETMKIYQMLADLITSDVRLTIE
SATQGE
>Mature_805_residues
SGWPRIYYKLLNLPLSILVKSKSIPAEPAQELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGALLPR
YVFIHGGPRVFTYYTPKEESVKLFHDYLDLHRSNPALDVQMVPVSVMFGRAPGREKGEDNPPLRMLNGVQKFFAISWLGR
DSFVRFSPSVSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKVIARAVEDEARSKKISH
EKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHEIVYVPCHRSHMDYLLLSYVLYH
QGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGT
LSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLKGLSKLRNLGQGYVNFGEPMPLMTYLNQ
HVPEWRESIDPIEAIRPAWLTPTVNSIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLDCYLDLMRNVPY
STDSTVPAASAGELIAHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLIMPSLMAAIITQHRRISRDALQQH
VEALYPMLKAELFLRWEREELASVIDALASEMQRQGLITLQDDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSANP
SINRSTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDTGDAEPAETMKIYQMLADLITSDVRLTIES
ATQGE

Specific function: De novo phospholipid biosynthesis; first step. [C]

COG id: COG2937

COG function: function code I; Glycerol-3-phosphate O-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPAT/DAPAT family [H]

Homologues:

Organism=Homo sapiens, GI7657134, Length=434, Percent_Identity=27.6497695852535, Blast_Score=153, Evalue=5e-37,
Organism=Homo sapiens, GI190358539, Length=272, Percent_Identity=32.7205882352941, Blast_Score=132, Evalue=9e-31,
Organism=Escherichia coli, GI87082362, Length=806, Percent_Identity=94.9131513647643, Blast_Score=1574, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988723, Length=302, Percent_Identity=31.7880794701987, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI25147672, Length=279, Percent_Identity=30.8243727598566, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71988728, Length=190, Percent_Identity=37.8947368421053, Blast_Score=134, Evalue=3e-31,
Organism=Drosophila melanogaster, GI17864692, Length=270, Percent_Identity=31.4814814814815, Blast_Score=146, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24650752, Length=499, Percent_Identity=25.8517034068136, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24650754, Length=499, Percent_Identity=25.8517034068136, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21357731, Length=493, Percent_Identity=25.9634888438134, Blast_Score=144, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR022284 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.15 [H]

Molecular weight: Translated: 91227; Mature: 91096

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGWPRIYYKLLNLPLSILVKSKSIPAEPAQELGLDTSRPIMYVLPYNSKADLLTLRAQC
CCCCHHHHHHHHHCCCEEEEECCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHH
LAHDLPDPLEPLEIDGALLPRYVFIHGGPRVFTYYTPKEESVKLFHDYLDLHRSNPALDV
HHCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEE
QMVPVSVMFGRAPGREKGEDNPPLRMLNGVQKFFAISWLGRDSFVRFSPSVSLRRMADEH
EEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHC
GTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKVIARAVEDEARSKKIS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHEI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEE
VYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNK
EEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
LYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLV
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCHHHHHHHHHHCCCCCCEEEE
PIYIGYEHVMEVGTYAKELRGATKEKESLPQMLKGLSKLRNLGQGYVNFGEPMPLMTYLN
EEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
QHVPEWRESIDPIEAIRPAWLTPTVNSIAADLMVRINNAGAANAMNLCCTALLASRQRSL
HCCHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHH
TREQLTEQLDCYLDLMRNVPYSTDSTVPAASAGELIAHALQMNKFEVEKDTIGDIIILPR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHEECCCCCCCEEEECC
EQAVLMTYYRNNIAHMLIMPSLMAAIITQHRRISRDALQQHVEALYPMLKAELFLRWERE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHH
ELASVIDALASEMQRQGLITLQDDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSAN
HHHHHHHHHHHHHHHCCCEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHEEEEECC
PSINRSTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDTGDAEPAET
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
MKIYQMLADLITSDVRLTIESATQGE
HHHHHHHHHHHCCCCEEEEECCCCCC
>Mature Secondary Structure 
SGWPRIYYKLLNLPLSILVKSKSIPAEPAQELGLDTSRPIMYVLPYNSKADLLTLRAQC
CCCHHHHHHHHHCCCEEEEECCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHH
LAHDLPDPLEPLEIDGALLPRYVFIHGGPRVFTYYTPKEESVKLFHDYLDLHRSNPALDV
HHCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEE
QMVPVSVMFGRAPGREKGEDNPPLRMLNGVQKFFAISWLGRDSFVRFSPSVSLRRMADEH
EEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHC
GTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKVIARAVEDEARSKKIS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHEI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEE
VYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNK
EEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
LYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLV
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCHHHHHHHHHHCCCCCCEEEE
PIYIGYEHVMEVGTYAKELRGATKEKESLPQMLKGLSKLRNLGQGYVNFGEPMPLMTYLN
EEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
QHVPEWRESIDPIEAIRPAWLTPTVNSIAADLMVRINNAGAANAMNLCCTALLASRQRSL
HCCHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHH
TREQLTEQLDCYLDLMRNVPYSTDSTVPAASAGELIAHALQMNKFEVEKDTIGDIIILPR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHEECCCCCCCEEEECC
EQAVLMTYYRNNIAHMLIMPSLMAAIITQHRRISRDALQQHVEALYPMLKAELFLRWERE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHH
ELASVIDALASEMQRQGLITLQDDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSAN
HHHHHHHHHHHHHHHCCCEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHEEEEECC
PSINRSTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDTGDAEPAET
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
MKIYQMLADLITSDVRLTIESATQGE
HHHHHHHHHHHCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA