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The map label for this gene is yyaE [H]

Identifier: 194737142

GI number: 194737142

Start: 747030

End: 749309

Strand: Direct

Name: yyaE [H]

Synonym: SeSA_A0769

Alternate gene names: 194737142

Gene position: 747030-749309 (Clockwise)

Preceding gene: 194736538

Following gene: 194736674

Centisome position: 15.86

GC content: 54.91

Gene sequence:

>2280_bases
ATGAGTAATGAGACAGGACATCTGAACAGACGTTCTTTTTTAAAGGGGATAGTGGCACTGGGCGCCGTTGCGGCTTTACC
CGGAGGATTACTGACCTCCCGATGCGCGCTTGCGCAGCCGCCTGTTCCCTTTAACCCTAAAACGTACAAAATTTATCGTA
ACGCGTGTCCGCGTAACTGCTATGACACCTGTAGCCTCAAGACATGGGTAAAGGACGGGGTCATTACTTTCGTGGAAGGC
GCGCCGGAATCAACATTTACTCACGGTACCCCTTGCGTCAAAGGGTTAAGCTATCCGCGCCGGGTTTATAGCCCCGATCG
TATTAAATATCCCATGGCGCAGGACGTTCGCGGTAGCGGCAACTGGCGTCGCATCTCATGGGAAGAGGCGATGCAGCGCA
TTGCCGCCAAAATGCTGGAGATTAAGAAAAAAGACGGTTCTATGCTCGGTCTGGCGCTGACCAAATATTCCGGTAAGTTT
GGCGTGCTGAACTATGCCGTTGAAGGGATGATGTCCTCGCTTGGCTACACCACCCGTTTCGCCGGTACGCCGTGCTGGCC
TGCCGGTATCGACGCGCAAAACTACGACATGGGCGACATGTGGTGTAACGACCCGGAAGATATGGTGAAAGCGAAATACA
TCATTATCTGGGGCGCGAACCCTGCCTGGTGCTCAATGCACAGCATGAAGTACATCTATCAGGCGCGCGAGAAAGGGGCG
AAGGTCGTGGTTATCGACCCGCTGCTGTCGCAGACTGCCGCCAAAGCCGATCTCTACCTGCGCGTACGGCCTGGCTCAGA
CGGCGCGCTGGCGCTGGGAATGGCGCGCCACCTGGTGGATAAAGGCCTGGTGGATCAAGATTTTGTCAACAACGATGCTC
ACGGCTATCCGGAATTTGAAGCCTATCTGCGTAACCATGTGACCGTGGAGTGGGCATCAGAAATCTGCGGCCTGTCTGCG
GATGTCATTCGCCAGCTGGCGGAAGAGTTTACGGCGGTTAAGCCGGCCACGGTCTGGATTGGTTACGGGATGCAGCGTCA
TGTCAACGGCGGTGCCAACGTTCGCGCTATCGATGCCTTTGTCGCTATGTCCGGCAACATCGGTGTCGAAGGCGGCGGCG
CGCGTTATGGTCATCTGCACACCTGGGGCTTTAACTACAGCGCCATGCTGCAGAAGCCGCCGGAGGGCGCTATTGGTATA
CCGGGAGCGGCGGGCACCACCAGTGAATTCGGGGCTGCCGCTGGCAGCGACGCCGTGCAGTACTCCGATCGCTCTCTGAA
TATCAACCAAACGGCGCAGGGGATTCTGGAGGCCAACGATCCGCCGGTTCGTATGCTGTGGGTCGCCTGTAAAAACCCGT
TTGCCCAGGATTTCGATCGCAGCAAGATGAAAAAAGCGTTTGAAAAACTGGAAATGGTGGTCTGCGCCGATCAGTTCTTC
AACGAAACGGTGCAACACGCTGATATCGTGCTGCCCGTTACCACCGCGTTTGAAGAGTGGAACGTGGATGCTTCTTACTG
GCACTACTGGCTTTCCATTAATCAGCCGACGATTAAGCCGATGTATGAAGCAAAATGCGACCTTGAAATCGCTACCATGC
TGTCGCGCGCCATTAATAAGATGGCGCCGGGTTCCTGTACTTTCCCGCAAGAGTTCGATCATAAGCGCTGGCTGGATCAG
GAGTTCAACGACGGTATGGCGAAAATGTTCGGCATCTCTTCCTGGGACGATCTGCTGGACGGGCCGAAAAAAGCGATCCT
GCCAAGCTCTGCCGCCTGGTATGACCGCAAGTTCAAAACGCCGTCAGGCAAGTATGAATTTAAATCTGAACTGGCGGAGA
AAAACGGCCACACCGCGCTGCCGGAATACAAACCGGAAGCCGAGAGCAAACTGCCGTTCCATCTGTTTACGCCGCACGTG
CAGTTTGGCCTGCACTCGCAGTTTATCAACCTGGACTGGATGCAGGTGTTCTACCCGGAACCGTTCGTTTATATCCATCC
TTCTTCCGCACAGAAAAAAGGCATCAGCGAGAACGATCTGGTCAAAGTTTTCAATGGCACCGGTGAAGTTGAGCTGCGGG
CAAAAGTCACCACCAACGTGCCGGAAGATTTTCTGGTGATGTATGAAGCCTGGTTCCCGAAACGGCAGTACAACGTGCAA
AACGTCGTGGCTGATACGCCTGCTGATATGGGGCTGATGAAAACTGGCGCGCCGGGCGCCGCTATCCACAGTCAGTTTGC
TGACGTTGTATTGATCGGTAAAGGGGAGTCCGTAGCATGA

Upstream 100 bases:

>100_bases
TATATCGAAAAAATAAAAACTCATGCGCAAACGACCACGTTATATACGGTGGCGGACATCTTATTTTATTGGCTTGATGA
ATTAAAACGAGAGTATCAAT

Downstream 100 bases:

>100_bases
GACGTGCGTTTTTAGTGAATAGCGATAAGTGCATCGGCTGCCGCGGCTGTGCTATGGCGTGTAAAAGCTTTAACCAACTG
GAGCCGGATCGCTTCTGGCG

Product: molybdopterin-containing oxidoreductase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 759; Mature: 758

Protein sequence:

>759_residues
MSNETGHLNRRSFLKGIVALGAVAALPGGLLTSRCALAQPPVPFNPKTYKIYRNACPRNCYDTCSLKTWVKDGVITFVEG
APESTFTHGTPCVKGLSYPRRVYSPDRIKYPMAQDVRGSGNWRRISWEEAMQRIAAKMLEIKKKDGSMLGLALTKYSGKF
GVLNYAVEGMMSSLGYTTRFAGTPCWPAGIDAQNYDMGDMWCNDPEDMVKAKYIIIWGANPAWCSMHSMKYIYQAREKGA
KVVVIDPLLSQTAAKADLYLRVRPGSDGALALGMARHLVDKGLVDQDFVNNDAHGYPEFEAYLRNHVTVEWASEICGLSA
DVIRQLAEEFTAVKPATVWIGYGMQRHVNGGANVRAIDAFVAMSGNIGVEGGGARYGHLHTWGFNYSAMLQKPPEGAIGI
PGAAGTTSEFGAAAGSDAVQYSDRSLNINQTAQGILEANDPPVRMLWVACKNPFAQDFDRSKMKKAFEKLEMVVCADQFF
NETVQHADIVLPVTTAFEEWNVDASYWHYWLSINQPTIKPMYEAKCDLEIATMLSRAINKMAPGSCTFPQEFDHKRWLDQ
EFNDGMAKMFGISSWDDLLDGPKKAILPSSAAWYDRKFKTPSGKYEFKSELAEKNGHTALPEYKPEAESKLPFHLFTPHV
QFGLHSQFINLDWMQVFYPEPFVYIHPSSAQKKGISENDLVKVFNGTGEVELRAKVTTNVPEDFLVMYEAWFPKRQYNVQ
NVVADTPADMGLMKTGAPGAAIHSQFADVVLIGKGESVA

Sequences:

>Translated_759_residues
MSNETGHLNRRSFLKGIVALGAVAALPGGLLTSRCALAQPPVPFNPKTYKIYRNACPRNCYDTCSLKTWVKDGVITFVEG
APESTFTHGTPCVKGLSYPRRVYSPDRIKYPMAQDVRGSGNWRRISWEEAMQRIAAKMLEIKKKDGSMLGLALTKYSGKF
GVLNYAVEGMMSSLGYTTRFAGTPCWPAGIDAQNYDMGDMWCNDPEDMVKAKYIIIWGANPAWCSMHSMKYIYQAREKGA
KVVVIDPLLSQTAAKADLYLRVRPGSDGALALGMARHLVDKGLVDQDFVNNDAHGYPEFEAYLRNHVTVEWASEICGLSA
DVIRQLAEEFTAVKPATVWIGYGMQRHVNGGANVRAIDAFVAMSGNIGVEGGGARYGHLHTWGFNYSAMLQKPPEGAIGI
PGAAGTTSEFGAAAGSDAVQYSDRSLNINQTAQGILEANDPPVRMLWVACKNPFAQDFDRSKMKKAFEKLEMVVCADQFF
NETVQHADIVLPVTTAFEEWNVDASYWHYWLSINQPTIKPMYEAKCDLEIATMLSRAINKMAPGSCTFPQEFDHKRWLDQ
EFNDGMAKMFGISSWDDLLDGPKKAILPSSAAWYDRKFKTPSGKYEFKSELAEKNGHTALPEYKPEAESKLPFHLFTPHV
QFGLHSQFINLDWMQVFYPEPFVYIHPSSAQKKGISENDLVKVFNGTGEVELRAKVTTNVPEDFLVMYEAWFPKRQYNVQ
NVVADTPADMGLMKTGAPGAAIHSQFADVVLIGKGESVA
>Mature_758_residues
SNETGHLNRRSFLKGIVALGAVAALPGGLLTSRCALAQPPVPFNPKTYKIYRNACPRNCYDTCSLKTWVKDGVITFVEGA
PESTFTHGTPCVKGLSYPRRVYSPDRIKYPMAQDVRGSGNWRRISWEEAMQRIAAKMLEIKKKDGSMLGLALTKYSGKFG
VLNYAVEGMMSSLGYTTRFAGTPCWPAGIDAQNYDMGDMWCNDPEDMVKAKYIIIWGANPAWCSMHSMKYIYQAREKGAK
VVVIDPLLSQTAAKADLYLRVRPGSDGALALGMARHLVDKGLVDQDFVNNDAHGYPEFEAYLRNHVTVEWASEICGLSAD
VIRQLAEEFTAVKPATVWIGYGMQRHVNGGANVRAIDAFVAMSGNIGVEGGGARYGHLHTWGFNYSAMLQKPPEGAIGIP
GAAGTTSEFGAAAGSDAVQYSDRSLNINQTAQGILEANDPPVRMLWVACKNPFAQDFDRSKMKKAFEKLEMVVCADQFFN
ETVQHADIVLPVTTAFEEWNVDASYWHYWLSINQPTIKPMYEAKCDLEIATMLSRAINKMAPGSCTFPQEFDHKRWLDQE
FNDGMAKMFGISSWDDLLDGPKKAILPSSAAWYDRKFKTPSGKYEFKSELAEKNGHTALPEYKPEAESKLPFHLFTPHVQ
FGLHSQFINLDWMQVFYPEPFVYIHPSSAQKKGISENDLVKVFNGTGEVELRAKVTTNVPEDFLVMYEAWFPKRQYNVQN
VVADTPADMGLMKTGAPGAAIHSQFADVVLIGKGESVA

Specific function: Terminal Reductase During Anaerobic Growth On Various Sulfoxide And N-Oxide Compounds (By Similarity). [C]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm Face Of The Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787870, Length=772, Percent_Identity=29.5336787564767, Blast_Score=248, Evalue=8e-67,
Organism=Escherichia coli, GI87081797, Length=785, Percent_Identity=28.6624203821656, Blast_Score=244, Evalue=2e-65,
Organism=Escherichia coli, GI171474008, Length=770, Percent_Identity=28.961038961039, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI87081994, Length=716, Percent_Identity=26.1173184357542, Blast_Score=182, Evalue=6e-47,
Organism=Escherichia coli, GI145693196, Length=712, Percent_Identity=26.9662921348315, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI1787231, Length=735, Percent_Identity=26.530612244898, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI3868721, Length=682, Percent_Identity=24.7800586510264, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI3868720, Length=490, Percent_Identity=24.8979591836735, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787778, Length=220, Percent_Identity=26.8181818181818, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 84240; Mature: 84109

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNETGHLNRRSFLKGIVALGAVAALPGGLLTSRCALAQPPVPFNPKTYKIYRNACPRNC
CCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCC
YDTCSLKTWVKDGVITFVEGAPESTFTHGTPCVKGLSYPRRVYSPDRIKYPMAQDVRGSG
HHCCCHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCCCCHHCCCCCCCCCCCHHCCCCCC
NWRRISWEEAMQRIAAKMLEIKKKDGSMLGLALTKYSGKFGVLNYAVEGMMSSLGYTTRF
CEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEC
AGTPCWPAGIDAQNYDMGDMWCNDPEDMVKAKYIIIWGANPAWCSMHSMKYIYQAREKGA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCC
KVVVIDPLLSQTAAKADLYLRVRPGSDGALALGMARHLVDKGLVDQDFVNNDAHGYPEFE
EEEEECHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHH
AYLRNHVTVEWASEICGLSADVIRQLAEEFTAVKPATVWIGYGMQRHVNGGANVRAIDAF
HHHHHCCEEEEHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCHHEECCCCCCEEEEEEE
VAMSGNIGVEGGGARYGHLHTWGFNYSAMLQKPPEGAIGIPGAAGTTSEFGAAAGSDAVQ
EEECCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCEE
YSDRSLNINQTAQGILEANDPPVRMLWVACKNPFAQDFDRSKMKKAFEKLEMVVCADQFF
ECCCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NETVQHADIVLPVTTAFEEWNVDASYWHYWLSINQPTIKPMYEAKCDLEIATMLSRAINK
HHHHHHCEEEEEEEHHHHHCCCCCEEEEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHH
MAPGSCTFPQEFDHKRWLDQEFNDGMAKMFGISSWDDLLDGPKKAILPSSAAWYDRKFKT
CCCCCCCCCHHHCHHHHHHHHHCCCHHHHHCCCCHHHHHCCCCHHCCCCCCHHHCCEECC
PSGKYEFKSELAEKNGHTALPEYKPEAESKLPFHLFTPHVQFGLHSQFINLDWMQVFYPE
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCHHCCCHHHEECCCEEEEECCC
PFVYIHPSSAQKKGISENDLVKVFNGTGEVELRAKVTTNVPEDFLVMYEAWFPKRQYNVQ
CEEEECCCCHHHCCCCCCCEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCHH
NVVADTPADMGLMKTGAPGAAIHSQFADVVLIGKGESVA
HHCCCCCCCCCEEECCCCCHHHHHCCCCEEEEECCCCCC
>Mature Secondary Structure 
SNETGHLNRRSFLKGIVALGAVAALPGGLLTSRCALAQPPVPFNPKTYKIYRNACPRNC
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCC
YDTCSLKTWVKDGVITFVEGAPESTFTHGTPCVKGLSYPRRVYSPDRIKYPMAQDVRGSG
HHCCCHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCCCCHHCCCCCCCCCCCHHCCCCCC
NWRRISWEEAMQRIAAKMLEIKKKDGSMLGLALTKYSGKFGVLNYAVEGMMSSLGYTTRF
CEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEC
AGTPCWPAGIDAQNYDMGDMWCNDPEDMVKAKYIIIWGANPAWCSMHSMKYIYQAREKGA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCC
KVVVIDPLLSQTAAKADLYLRVRPGSDGALALGMARHLVDKGLVDQDFVNNDAHGYPEFE
EEEEECHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHH
AYLRNHVTVEWASEICGLSADVIRQLAEEFTAVKPATVWIGYGMQRHVNGGANVRAIDAF
HHHHHCCEEEEHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCHHEECCCCCCEEEEEEE
VAMSGNIGVEGGGARYGHLHTWGFNYSAMLQKPPEGAIGIPGAAGTTSEFGAAAGSDAVQ
EEECCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCEE
YSDRSLNINQTAQGILEANDPPVRMLWVACKNPFAQDFDRSKMKKAFEKLEMVVCADQFF
ECCCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NETVQHADIVLPVTTAFEEWNVDASYWHYWLSINQPTIKPMYEAKCDLEIATMLSRAINK
HHHHHHCEEEEEEEHHHHHCCCCCEEEEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHH
MAPGSCTFPQEFDHKRWLDQEFNDGMAKMFGISSWDDLLDGPKKAILPSSAAWYDRKFKT
CCCCCCCCCHHHCHHHHHHHHHCCCHHHHHCCCCHHHHHCCCCHHCCCCCCHHHCCEECC
PSGKYEFKSELAEKNGHTALPEYKPEAESKLPFHLFTPHVQFGLHSQFINLDWMQVFYPE
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCHHCCCHHHEECCCEEEEECCC
PFVYIHPSSAQKKGISENDLVKVFNGTGEVELRAKVTTNVPEDFLVMYEAWFPKRQYNVQ
CEEEECCCCHHHCCCCCCCEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCHH
NVVADTPADMGLMKTGAPGAAIHSQFADVVLIGKGESVA
HHCCCCCCCCCEEECCCCCHHHHHCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1552862 [H]