Click here to switch to the map view.

The map label for this gene is frlD [H]

Identifier: 194737047

GI number: 194737047

Start: 3656440

End: 3657285

Strand: Reverse

Name: frlD [H]

Synonym: SeSA_A3794

Alternate gene names: 194737047

Gene position: 3657285-3656440 (Counterclockwise)

Preceding gene: 194734834

Following gene: 194738372

Centisome position: 77.66

GC content: 47.28

Gene sequence:

>846_bases
ATGAGCATCAGCGTATTGGGTATTGGCGACAACGTTGTCGATAAATACCTGCATTCCGGCATCATGTACCCCGGCGGTAA
TGCATTAAATTTTGCTGTCTATGCGAAATTAGCAGACATCCCCAGCGCGTTTATGGGGGCGTTTGGCAATGACGACGCCG
CGCAGCACGTACAGGATGTATTACACCAGCTACAGATAGACATCTCTCACAGCCGCCATTATACCGGCGAAAATGGGTAT
GCCTGTATCCGTCTCACGCATGGCGATCGGCAATTTGTCGCCAGCAACAAAAACGGCGTATTGCGGGAACATCCTTTTAG
CTTGTCTGACGACGATCTTCGTTATATATCACAATTTACCTTAGTCCATTCCAGTATTAACGGCCATCTGGAATCGGAGC
TGGAGAAAATTAAACAACAAACCGTCTTACTCTCTTTTGATTTTTCCGGGCGCGGTACAGACGACTATTTTGAAAAGGTA
TGCCCGTGGGTAGATTATGGATTTGTCTCCTGTAGTGGGTTATCGCCAGATGAAATCAAAATAAAACTCAATAAACTTTA
TCGTTATGGCTGTCGGCATCTTATTGCCACCTGCGGGCATGAAAAAGTTTATTATTTTTCCGGCAGGGATTATCTGGAGT
GGCAACCTGTTTATATCGAACCTGTCGATACGCTGGGCGCAGGCGACGCCTTCTTAACCGGTTTTTTGCTTTCCATTTTG
CAATCGGGTATGGCGGAACCCGATAAAGAAAGCGTGTTACGCGCCATGCGGCAGGGCGGGAAATCGGCGGCGCAGGTGTT
ATCTCATTACGGCGCATTTGGTTTTGGTAAACCGTTTGCACAATAG

Upstream 100 bases:

>100_bases
AACGACGCGCCGCTATATGTGGAAAGTGGAATATTAATTACATCAGGATGGATAAAAAAGCAGGGACGCTTTTTATTGTA
AAGACAAACAAGGAATAATG

Downstream 100 bases:

>100_bases
GTTACGTCCCTCAATGTAAAGCGACACTCACTCCAGATAACCCAGGAGGAAGTATGTTTTGGACGGAATTATGTTTTATC
CTTGTGGCCCTGATGATAGG

Product: PfkB domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSISVLGIGDNVVDKYLHSGIMYPGGNALNFAVYAKLADIPSAFMGAFGNDDAAQHVQDVLHQLQIDISHSRHYTGENGY
ACIRLTHGDRQFVASNKNGVLREHPFSLSDDDLRYISQFTLVHSSINGHLESELEKIKQQTVLLSFDFSGRGTDDYFEKV
CPWVDYGFVSCSGLSPDEIKIKLNKLYRYGCRHLIATCGHEKVYYFSGRDYLEWQPVYIEPVDTLGAGDAFLTGFLLSIL
QSGMAEPDKESVLRAMRQGGKSAAQVLSHYGAFGFGKPFAQ

Sequences:

>Translated_281_residues
MSISVLGIGDNVVDKYLHSGIMYPGGNALNFAVYAKLADIPSAFMGAFGNDDAAQHVQDVLHQLQIDISHSRHYTGENGY
ACIRLTHGDRQFVASNKNGVLREHPFSLSDDDLRYISQFTLVHSSINGHLESELEKIKQQTVLLSFDFSGRGTDDYFEKV
CPWVDYGFVSCSGLSPDEIKIKLNKLYRYGCRHLIATCGHEKVYYFSGRDYLEWQPVYIEPVDTLGAGDAFLTGFLLSIL
QSGMAEPDKESVLRAMRQGGKSAAQVLSHYGAFGFGKPFAQ
>Mature_280_residues
SISVLGIGDNVVDKYLHSGIMYPGGNALNFAVYAKLADIPSAFMGAFGNDDAAQHVQDVLHQLQIDISHSRHYTGENGYA
CIRLTHGDRQFVASNKNGVLREHPFSLSDDDLRYISQFTLVHSSINGHLESELEKIKQQTVLLSFDFSGRGTDDYFEKVC
PWVDYGFVSCSGLSPDEIKIKLNKLYRYGCRHLIATCGHEKVYYFSGRDYLEWQPVYIEPVDTLGAGDAFLTGFLLSILQ
SGMAEPDKESVLRAMRQGGKSAAQVLSHYGAFGFGKPFAQ

Specific function: Catalyzes the phosphorylation of a range of fructosamines to fructosamine 6-phosphates [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1789775, Length=269, Percent_Identity=29.7397769516729, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: NA

Molecular weight: Translated: 31196; Mature: 31065

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISVLGIGDNVVDKYLHSGIMYPGGNALNFAVYAKLADIPSAFMGAFGNDDAAQHVQDV
CEEEEEECCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHCCHHHHHCCCCCHHHHHHHHH
LHQLQIDISHSRHYTGENGYACIRLTHGDRQFVASNKNGVLREHPFSLSDDDLRYISQFT
HHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCEECCCCCCCCHHHHHHHHHH
LVHSSINGHLESELEKIKQQTVLLSFDFSGRGTDDYFEKVCPWVDYGFVSCSGLSPDEIK
HHHHHHCCHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHCCHHHCCCEEECCCCCCCEE
IKLNKLYRYGCRHLIATCGHEKVYYFSGRDYLEWQPVYIEPVDTLGAGDAFLTGFLLSIL
EHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEECCEEECCCCCCCCCHHHHHHHHHHHH
QSGMAEPDKESVLRAMRQGGKSAAQVLSHYGAFGFGKPFAQ
HHCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SISVLGIGDNVVDKYLHSGIMYPGGNALNFAVYAKLADIPSAFMGAFGNDDAAQHVQDV
EEEEEECCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHCCHHHHHCCCCCHHHHHHHHH
LHQLQIDISHSRHYTGENGYACIRLTHGDRQFVASNKNGVLREHPFSLSDDDLRYISQFT
HHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCEECCCCCCCCHHHHHHHHHH
LVHSSINGHLESELEKIKQQTVLLSFDFSGRGTDDYFEKVCPWVDYGFVSCSGLSPDEIK
HHHHHHCCHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHCCHHHCCCEEECCCCCCCEE
IKLNKLYRYGCRHLIATCGHEKVYYFSGRDYLEWQPVYIEPVDTLGAGDAFLTGFLLSIL
EHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEECCEEECCCCCCCCCHHHHHHHHHHHH
QSGMAEPDKESVLRAMRQGGKSAAQVLSHYGAFGFGKPFAQ
HHCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]