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The map label for this gene is codA [H]

Identifier: 194737042

GI number: 194737042

Start: 3402211

End: 3403491

Strand: Direct

Name: codA [H]

Synonym: SeSA_A3527

Alternate gene names: 194737042

Gene position: 3402211-3403491 (Clockwise)

Preceding gene: 194736575

Following gene: 194735949

Centisome position: 72.25

GC content: 55.19

Gene sequence:

>1281_bases
ATGCAGAACAATAACATCACCATTCTTCAGGCGCGTCTGCAGGGACACGAAGGATTATGGCAGATTACGATTGAAAACGG
GCGCTTTAGCCGGATTGAGCCTCAGGAAGCCGCATCGTTACCGCAGGGCGAAGTGCTTGATGCCGAAGGCGGTCTGGCTA
TTCCACCGTTTGTTGAGCCACATATCCACCTGGATACCACGCAAACGGCGGGTGAACCGAGCTGGAACCAGTCCGGCACA
CTGTTTGAAGGGATTGAGCGCTGGGCAGAACGTAAAGCAATGCTCACGCATGAAGATGTGAAAGCGCGCGCGATGCAGAC
CCTGAAATGGCAGATGGCTAACGGCATCCAGTACGTTCGTACTCACGTTGACGTTTCAGATCCTACGCTCACCGCGCTGA
AAGCCATGCTGGAAGTGAAGCAAGAGGTTGCGCCGTGGGTAGACCTACAAATCGTCGCCTTTCCGCAAGAAGGTATTCTG
TCTTATCCCAACGGTGAAGCGCTGTTAGAGGAAGCCGTGCGTTTGGGCGCTGACGTTATTGGTGCCATTCCGCACTTTGA
GTTCACGCGCGAATATGGCGTTGAATCGCTGCACAAAATCTTTGCACTGGCGCAGAAATACGATCGCTTGATCGATGTGC
ACTGCGACGAAATTGATGACGAGCAGTCTCGCTTTGTCGAAACGGTCGCGGCGCTGGCGCATCGTGATGGCATGGGGGCG
CGCGTGACCGCCAGCCACACCACGGCTATGCACTCGTACAACGGCGCGTATGCGTCACGCCTGTTCCGCCTGTTGAAAAT
GTCGGGGATTAACTTCGTCGCCAACCCGCTGGTGAATATTCATCTGCAAGGGCGGTTTGACACTTACCCGAAACGTCGTG
GCGTCACGCGGGTGAAAGAGATGCTGGAAGCGGGGATCAACGTCTGCTTTGGCCATGATGACGTCTTCGATCCGTGGTAT
CCATTAGGCACGGCAAATATGCTGCAGGTGCTGCATATGGGGTTACACGTTTGCCAGTTGATGGGGTATGGGCAAATCAA
CGATGGGTTAAATCTGATCACTACCCACAGCGCAAAAACCCTGCATTTACAGGACTACAGTCTGAGCGTCGGCAATGCCG
CGAATCTGGTTATCTTACCCGCTGAGAATGGATTCGATGCGGTACGTCGCCAGACGCCTGCCCGTTACTCGATTCGCCAC
GGGCGGGTAATTGCCGAGACGGTGCCGAGCCAGACGACGCTGCACCTGCCCCAGCCGGAAGCCGTGACGTTTAAGCGTTA
A

Upstream 100 bases:

>100_bases
GGTATTGTGCCCGTCAACGCCGTACTCGGCGGCGTCTTCAGCTATATCCTGCTGAATCCACTTTTCAACCGCAGCCTTGC
TAAATCACCAGAGGTCAGCC

Downstream 100 bases:

>100_bases
CCCGTCATACCCGCGCTCTCCGGCACATTCACCACGCAGCCCGTAAGGGGCTGCGTTCGGAAGACTGCTCCGGCAAGAGA
TTCAGGCCGCCAGCAGACTG

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MQNNNITILQARLQGHEGLWQITIENGRFSRIEPQEAASLPQGEVLDAEGGLAIPPFVEPHIHLDTTQTAGEPSWNQSGT
LFEGIERWAERKAMLTHEDVKARAMQTLKWQMANGIQYVRTHVDVSDPTLTALKAMLEVKQEVAPWVDLQIVAFPQEGIL
SYPNGEALLEEAVRLGADVIGAIPHFEFTREYGVESLHKIFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHRDGMGA
RVTASHTTAMHSYNGAYASRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGVTRVKEMLEAGINVCFGHDDVFDPWY
PLGTANMLQVLHMGLHVCQLMGYGQINDGLNLITTHSAKTLHLQDYSLSVGNAANLVILPAENGFDAVRRQTPARYSIRH
GRVIAETVPSQTTLHLPQPEAVTFKR

Sequences:

>Translated_426_residues
MQNNNITILQARLQGHEGLWQITIENGRFSRIEPQEAASLPQGEVLDAEGGLAIPPFVEPHIHLDTTQTAGEPSWNQSGT
LFEGIERWAERKAMLTHEDVKARAMQTLKWQMANGIQYVRTHVDVSDPTLTALKAMLEVKQEVAPWVDLQIVAFPQEGIL
SYPNGEALLEEAVRLGADVIGAIPHFEFTREYGVESLHKIFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHRDGMGA
RVTASHTTAMHSYNGAYASRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGVTRVKEMLEAGINVCFGHDDVFDPWY
PLGTANMLQVLHMGLHVCQLMGYGQINDGLNLITTHSAKTLHLQDYSLSVGNAANLVILPAENGFDAVRRQTPARYSIRH
GRVIAETVPSQTTLHLPQPEAVTFKR
>Mature_426_residues
MQNNNITILQARLQGHEGLWQITIENGRFSRIEPQEAASLPQGEVLDAEGGLAIPPFVEPHIHLDTTQTAGEPSWNQSGT
LFEGIERWAERKAMLTHEDVKARAMQTLKWQMANGIQYVRTHVDVSDPTLTALKAMLEVKQEVAPWVDLQIVAFPQEGIL
SYPNGEALLEEAVRLGADVIGAIPHFEFTREYGVESLHKIFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHRDGMGA
RVTASHTTAMHSYNGAYASRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGVTRVKEMLEAGINVCFGHDDVFDPWY
PLGTANMLQVLHMGLHVCQLMGYGQINDGLNLITTHSAKTLHLQDYSLSVGNAANLVILPAENGFDAVRRQTPARYSIRH
GRVIAETVPSQTTLHLPQPEAVTFKR

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=427, Percent_Identity=83.3723653395785, Blast_Score=753, Evalue=0.0,
Organism=Escherichia coli, GI1786517, Length=315, Percent_Identity=26.3492063492064, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 47552; Mature: 47552

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNNNITILQARLQGHEGLWQITIENGRFSRIEPQEAASLPQGEVLDAEGGLAIPPFVEP
CCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHCCCCCCEEECCCCEECCCCCCC
HIHLDTTQTAGEPSWNQSGTLFEGIERWAERKAMLTHEDVKARAMQTLKWQMANGIQYVR
CEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEHH
THVDVSDPTLTALKAMLEVKQEVAPWVDLQIVAFPQEGILSYPNGEALLEEAVRLGADVI
EECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCHHHH
GAIPHFEFTREYGVESLHKIFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHRDGMGA
HCCCCHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
RVTASHTTAMHSYNGAYASRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGVTRVKE
EEEECHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCHHCCHHHHHH
MLEAGINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQLMGYGQINDGLNLITTHSAKT
HHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEE
LHLQDYSLSVGNAANLVILPAENGFDAVRRQTPARYSIRHGRVIAETVPSQTTLHLPQPE
EEEEECEEECCCCCCEEEEECCCCHHHHHHCCCCCEECCCCEEEEECCCCCCEEECCCCC
AVTFKR
CCCCCC
>Mature Secondary Structure
MQNNNITILQARLQGHEGLWQITIENGRFSRIEPQEAASLPQGEVLDAEGGLAIPPFVEP
CCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHCCCCCCEEECCCCEECCCCCCC
HIHLDTTQTAGEPSWNQSGTLFEGIERWAERKAMLTHEDVKARAMQTLKWQMANGIQYVR
CEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEHH
THVDVSDPTLTALKAMLEVKQEVAPWVDLQIVAFPQEGILSYPNGEALLEEAVRLGADVI
EECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCHHHH
GAIPHFEFTREYGVESLHKIFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHRDGMGA
HCCCCHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
RVTASHTTAMHSYNGAYASRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGVTRVKE
EEEECHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCHHCCHHHHHH
MLEAGINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQLMGYGQINDGLNLITTHSAKT
HHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEE
LHLQDYSLSVGNAANLVILPAENGFDAVRRQTPARYSIRHGRVIAETVPSQTTLHLPQPE
EEEEECEEECCCCCCEEEEECCCCHHHHHHCCCCCEECCCCEEEEECCCCCCEEECCCCC
AVTFKR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]