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The map label for this gene is yjcC [H]

Identifier: 194736945

GI number: 194736945

Start: 4392941

End: 4394542

Strand: Direct

Name: yjcC [H]

Synonym: SeSA_A4515

Alternate gene names: 194736945

Gene position: 4392941-4394542 (Clockwise)

Preceding gene: 194735935

Following gene: 194737432

Centisome position: 93.29

GC content: 47.63

Gene sequence:

>1602_bases
ATGAGTCAAAGCACACGACGCAAGGTGTTGAGATTTCTCGGAACGATCATTGTGGTGTTACTTCCTGTATTGCTGGCGAT
CTGGTTTGCTCATATCCGGGCAGTCTCTGAAACCAGAAATCAGTTACATTCATTTGCGCAGTTGGTATTAGATAAAACGG
AGCGGGTTATCCTGCAAGCAGATTTAGCCCGCGATGCCGCTGAACAATATCAGGGGCAAGCCTGTACGCCAGCCCATCAA
CAGCGAATGCTGAATATTATCCGCGGTCGTTTGTACATTTATGAGTTGATTTATGCTAAGGGCCAGCGTTTTCTATGCTC
TACGGTTATGACGCCAACAAGTCCTTATTTTATTCCCCGCGCTGACTATAAACGAAAGCCTGACATCGCTATTTATTACT
ATCGTGATACGCCTTTTTTCAACGGTTATAAAATGACATATATGCAGCGGGGAAACTATGTCGCGGTTATCAATCCCTTA
TCTTATAGCGAGGTGATGTCAGACGATCCGGCGTTGGCCTGGGGAATGTATGATACGGTGACCAACACCTTTTTCTCTCT
GAGTGAACAGGCGCAGGCTGATCACCTATTACCTTTGGTACGACGGAGTGAACCTGTGTTCCAACAGGGTGAGCGTTTTT
ATACTCTGGTTAAATCAGCAAAACGACCGGTTGCCGCGATTGTGTCAACCTCAAAGCAACGCTTTTACCAGAACCTCTTT
CATCAGCTTACGTTAACGCTACCGTTAGGGATCATCTGTAGCATTATCGTCTTATTTATGTGGTCACGATCCCGGCAGGC
ATATTACTCACCGCGTCGATTGCTGCAACGGGCCATTACCAGGCACCAGCTTTGCCTTCATTATCAGCCGATCATTGATA
TCCGAAACGGGACATGTGTAGGTGCCGAAGCGCTATTGCGTTGGCCGGGCTATCACGGTCCGGTGATGAGCCCGTGCGAA
TTTATTCCGCTGGCGGAAAAAGAGGGGATGATTGAGCAGATCACCGATTATGTCGTCGAAGAGGTATTTAATGATTTAGG
TGGTTTTCTGGCCGCGCACCCGCATCTTTATGTCTCTATCAATCTCTCTGCCGCCGATTTTCTCTCTTCCCGACTAATTG
TGATGATTCATGAAAAAACGCGTCAGCATTCAGTGCTTGCGCAACAGATAAAGGTTGAAGTGACCGAGCGCGGATTTATT
GATGTGCCTAAAATGACGCCGATTATTCAGGCGTTTCGCCAGGCGGGATACGAGGTGGCAATTGATGACTTTGGTACCGG
CTATTCGAACTTGCATAACCTGTACTCATTAAATGTCGACCTTTTAAAAATTGATAAATCTTTTGTCGACACGCTAACCA
CTAATAGCGCCAGCCATTTGATTGTGGAACATATTATTGAAATGGCGCAAAGTTTGCGGCTAAAAATCATTGCGGAGGGG
GTTGAAACGGCTGAACAGGTTAGCTGGTTGCTAAAACGCGGCGTTCAGTATTGTCAGGGATGGCACTTTGCGAAGGCGTT
ACCACCGCAGGAATTCATCTCCTGGCTACAACAAACGCCCGCGCCTCTGACGATACGCGGGCAGACGCCCTACAGGCGGT
GA

Upstream 100 bases:

>100_bases
GTTGCTAATATTGATAAATTCATGCACCGTAAACCTCCGTTTGGTTCACGTCTTATTTTGCCAACAATAGTCACAAATAA
TGCAGGGAAATAGGCTGAAA

Downstream 100 bases:

>100_bases
CGGTAATCGCTGGGAGTGCGATCGAACTCGCGGCGGAATACACGCGAGAAGGTTTGCTGCGATACATAGCCCAGGTCCAT
CGCGATATCAAAAATCGGGC

Product: cyclic diguanylate phosphodiesterase (EAL) domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MSQSTRRKVLRFLGTIIVVLLPVLLAIWFAHIRAVSETRNQLHSFAQLVLDKTERVILQADLARDAAEQYQGQACTPAHQ
QRMLNIIRGRLYIYELIYAKGQRFLCSTVMTPTSPYFIPRADYKRKPDIAIYYYRDTPFFNGYKMTYMQRGNYVAVINPL
SYSEVMSDDPALAWGMYDTVTNTFFSLSEQAQADHLLPLVRRSEPVFQQGERFYTLVKSAKRPVAAIVSTSKQRFYQNLF
HQLTLTLPLGIICSIIVLFMWSRSRQAYYSPRRLLQRAITRHQLCLHYQPIIDIRNGTCVGAEALLRWPGYHGPVMSPCE
FIPLAEKEGMIEQITDYVVEEVFNDLGGFLAAHPHLYVSINLSAADFLSSRLIVMIHEKTRQHSVLAQQIKVEVTERGFI
DVPKMTPIIQAFRQAGYEVAIDDFGTGYSNLHNLYSLNVDLLKIDKSFVDTLTTNSASHLIVEHIIEMAQSLRLKIIAEG
VETAEQVSWLLKRGVQYCQGWHFAKALPPQEFISWLQQTPAPLTIRGQTPYRR

Sequences:

>Translated_533_residues
MSQSTRRKVLRFLGTIIVVLLPVLLAIWFAHIRAVSETRNQLHSFAQLVLDKTERVILQADLARDAAEQYQGQACTPAHQ
QRMLNIIRGRLYIYELIYAKGQRFLCSTVMTPTSPYFIPRADYKRKPDIAIYYYRDTPFFNGYKMTYMQRGNYVAVINPL
SYSEVMSDDPALAWGMYDTVTNTFFSLSEQAQADHLLPLVRRSEPVFQQGERFYTLVKSAKRPVAAIVSTSKQRFYQNLF
HQLTLTLPLGIICSIIVLFMWSRSRQAYYSPRRLLQRAITRHQLCLHYQPIIDIRNGTCVGAEALLRWPGYHGPVMSPCE
FIPLAEKEGMIEQITDYVVEEVFNDLGGFLAAHPHLYVSINLSAADFLSSRLIVMIHEKTRQHSVLAQQIKVEVTERGFI
DVPKMTPIIQAFRQAGYEVAIDDFGTGYSNLHNLYSLNVDLLKIDKSFVDTLTTNSASHLIVEHIIEMAQSLRLKIIAEG
VETAEQVSWLLKRGVQYCQGWHFAKALPPQEFISWLQQTPAPLTIRGQTPYRR
>Mature_532_residues
SQSTRRKVLRFLGTIIVVLLPVLLAIWFAHIRAVSETRNQLHSFAQLVLDKTERVILQADLARDAAEQYQGQACTPAHQQ
RMLNIIRGRLYIYELIYAKGQRFLCSTVMTPTSPYFIPRADYKRKPDIAIYYYRDTPFFNGYKMTYMQRGNYVAVINPLS
YSEVMSDDPALAWGMYDTVTNTFFSLSEQAQADHLLPLVRRSEPVFQQGERFYTLVKSAKRPVAAIVSTSKQRFYQNLFH
QLTLTLPLGIICSIIVLFMWSRSRQAYYSPRRLLQRAITRHQLCLHYQPIIDIRNGTCVGAEALLRWPGYHGPVMSPCEF
IPLAEKEGMIEQITDYVVEEVFNDLGGFLAAHPHLYVSINLSAADFLSSRLIVMIHEKTRQHSVLAQQIKVEVTERGFID
VPKMTPIIQAFRQAGYEVAIDDFGTGYSNLHNLYSLNVDLLKIDKSFVDTLTTNSASHLIVEHIIEMAQSLRLKIIAEGV
ETAEQVSWLLKRGVQYCQGWHFAKALPPQEFISWLQQTPAPLTIRGQTPYRR

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=528, Percent_Identity=64.9621212121212, Blast_Score=705, Evalue=0.0,
Organism=Escherichia coli, GI87081743, Length=519, Percent_Identity=33.5260115606936, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI87081845, Length=279, Percent_Identity=31.1827956989247, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI87081921, Length=254, Percent_Identity=38.9763779527559, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1788502, Length=253, Percent_Identity=32.0158102766798, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1787541, Length=245, Percent_Identity=33.469387755102, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87081980, Length=252, Percent_Identity=33.3333333333333, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI226510982, Length=239, Percent_Identity=36.8200836820084, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1786507, Length=244, Percent_Identity=32.7868852459016, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788849, Length=245, Percent_Identity=32.6530612244898, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87082096, Length=239, Percent_Identity=31.3807531380753, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787055, Length=247, Percent_Identity=29.5546558704453, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787410, Length=151, Percent_Identity=29.8013245033113, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 61167; Mature: 61035

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSTRRKVLRFLGTIIVVLLPVLLAIWFAHIRAVSETRNQLHSFAQLVLDKTERVILQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLARDAAEQYQGQACTPAHQQRMLNIIRGRLYIYELIYAKGQRFLCSTVMTPTSPYFIPR
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEECC
ADYKRKPDIAIYYYRDTPFFNGYKMTYMQRGNYVAVINPLSYSEVMSDDPALAWGMYDTV
CCCCCCCCEEEEEEECCCCCCCEEEEEEECCCEEEEECCCCHHHHHCCCCCEEHHHHHHH
TNTFFSLSEQAQADHLLPLVRRSEPVFQQGERFYTLVKSAKRPVAAIVSTSKQRFYQNLF
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
HQLTLTLPLGIICSIIVLFMWSRSRQAYYSPRRLLQRAITRHQLCLHYQPIIDIRNGTCV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEE
GAEALLRWPGYHGPVMSPCEFIPLAEKEGMIEQITDYVVEEVFNDLGGFLAAHPHLYVSI
CHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
NLSAADFLSSRLIVMIHEKTRQHSVLAQQIKVEVTERGFIDVPKMTPIIQAFRQAGYEVA
ECCHHHHHHCCEEEEEECHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHCCCEEE
IDDFGTGYSNLHNLYSLNVDLLKIDKSFVDTLTTNSASHLIVEHIIEMAQSLRLKIIAEG
ECCCCCCHHHHHHHHCCCEEHEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VETAEQVSWLLKRGVQYCQGWHFAKALPPQEFISWLQQTPAPLTIRGQTPYRR
HHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure 
SQSTRRKVLRFLGTIIVVLLPVLLAIWFAHIRAVSETRNQLHSFAQLVLDKTERVILQA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLARDAAEQYQGQACTPAHQQRMLNIIRGRLYIYELIYAKGQRFLCSTVMTPTSPYFIPR
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEECC
ADYKRKPDIAIYYYRDTPFFNGYKMTYMQRGNYVAVINPLSYSEVMSDDPALAWGMYDTV
CCCCCCCCEEEEEEECCCCCCCEEEEEEECCCEEEEECCCCHHHHHCCCCCEEHHHHHHH
TNTFFSLSEQAQADHLLPLVRRSEPVFQQGERFYTLVKSAKRPVAAIVSTSKQRFYQNLF
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
HQLTLTLPLGIICSIIVLFMWSRSRQAYYSPRRLLQRAITRHQLCLHYQPIIDIRNGTCV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEE
GAEALLRWPGYHGPVMSPCEFIPLAEKEGMIEQITDYVVEEVFNDLGGFLAAHPHLYVSI
CHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
NLSAADFLSSRLIVMIHEKTRQHSVLAQQIKVEVTERGFIDVPKMTPIIQAFRQAGYEVA
ECCHHHHHHCCEEEEEECHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHCCCEEE
IDDFGTGYSNLHNLYSLNVDLLKIDKSFVDTLTTNSASHLIVEHIIEMAQSLRLKIIAEG
ECCCCCCHHHHHHHHCCCEEHEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VETAEQVSWLLKRGVQYCQGWHFAKALPPQEFISWLQQTPAPLTIRGQTPYRR
HHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]