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The map label for this gene is intZ [H]

Identifier: 194736776

GI number: 194736776

Start: 3804662

End: 3805924

Strand: Direct

Name: intZ [H]

Synonym: SeSA_A3935

Alternate gene names: 194736776

Gene position: 3804662-3805924 (Clockwise)

Preceding gene: 194737026

Following gene: 194735177

Centisome position: 80.79

GC content: 48.61

Gene sequence:

>1263_bases
ATGTCAAAACTGACAGACTTACAAATCAGAGCATGGATAAAATCGGGTGAGCATTTTGCTGGTCGCTCTGATGGGGGTGG
GCTGTATTTGTGCTTCCCAGAAAATTACTCAGTACCCTTTTGGCGTTTGCGTTATCGTTTTGCGGGCAAACAGCGATCGC
TGGTCATAGGCACGTACACCGAGCTGTCACTCGCTAAAGCACGAGCAAAAGCTAAAGAACAGTCAGCACGGGTTGCATTG
GGTTATGACGTTGCGGGGGAAAAGCAAGAACGCAAAGCTGAAGCGCTGAGGAAGATGGAGGATGAAAAGCACGCGCTACG
TGTTTCAGAACTTGCAGCTGAATACTTTGAACGCCAGATTCTCAATCGGTGGAAGCATCCAGACATCCTACGTCGTCGCA
TAGATAAGGACATTAATCCGGCAATCGGTCGCCTCAGAATTGAAGAGGTTAAAGCCAGGGATATTGATGACATGCTGCAA
AAAATAGTTCAGCGTGGTGCACCTACAGTCGCTAACGATGTGCTCAGATGGACTCGTCGTATCTTCGATTACGGGATAAG
ACGGCATATGCTAGAAACGAATCCTACTAGTGCTTTTGAAATTGATGATGCAGGTGGGCAGGAAAAAAGCAGGGAACGCT
GGCTAAGCCGAGAAGAGCTTGCGCGATTCTTACAGGCAATGCCGATGACAAAAGGTTTCTCACGTCAGAACGAACTGACA
ATGAAACTTCTGCTGGTGTTTTGCTGCCGCAAGATGGAGCTTTGCGGTGCTCGTTGGGAAGAGTTCGATTTTAATGAAGC
AGTTTGGCGCTTACCCGCAGAGCGGGTAAAGAATGGCGATGCGATTGATATACCTATCCCGGCAGTAGCTCTTGAATGGC
TGAAGGAACTGCATCAAATGTCCTGCAATAGCCAGTGGGTGCTGCCAGCAAGAAAGATGCAGCACCGGATGATTCCTCAC
ATTCAGGAAAGTACACTCCCCGTAGCATTGAGCAAGGTGAAGGGTAACCTCCCCGACGTACCTAATTTTACTATTCATGA
TTTTCGACGTACCGCGCGATCGCACCTGGCTGCATTAGGGATTGATCCAGTAGTTGCAGAACGCTGCCTGAACCACAGAA
TCAAAGGTGTTGAGGGGATATACAACCGTTATCAGTATTTCGATGAGAGGAAGCAGGCGTTGGAGCTGTGGGCTGACTTG
CTGGTTTCTTTAGAAAGAGGTGAAGGCTATAACGTGACGCCGTTGAGAAAGGGGATTGCATGA

Upstream 100 bases:

>100_bases
TATCGTATCACTAGAGCGCGTGTTTCGTATGTACATAGACGTGTACATACTGGCATTTATGACACGCAGTTTATGTACAC
AGCAATGAGACAAGATAAGC

Downstream 100 bases:

>100_bases
AATTCACCAGTAAGTAATGCACAGTCGGGGGTGTTACATGTCAACAGTTGGGTTTTCAATCTTCTTCTCGCGCCATATCC
TTCTAAATGGTCAGCACTTG

Product: site-specific recombinase, phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSKLTDLQIRAWIKSGEHFAGRSDGGGLYLCFPENYSVPFWRLRYRFAGKQRSLVIGTYTELSLAKARAKAKEQSARVAL
GYDVAGEKQERKAEALRKMEDEKHALRVSELAAEYFERQILNRWKHPDILRRRIDKDINPAIGRLRIEEVKARDIDDMLQ
KIVQRGAPTVANDVLRWTRRIFDYGIRRHMLETNPTSAFEIDDAGGQEKSRERWLSREELARFLQAMPMTKGFSRQNELT
MKLLLVFCCRKMELCGARWEEFDFNEAVWRLPAERVKNGDAIDIPIPAVALEWLKELHQMSCNSQWVLPARKMQHRMIPH
IQESTLPVALSKVKGNLPDVPNFTIHDFRRTARSHLAALGIDPVVAERCLNHRIKGVEGIYNRYQYFDERKQALELWADL
LVSLERGEGYNVTPLRKGIA

Sequences:

>Translated_420_residues
MSKLTDLQIRAWIKSGEHFAGRSDGGGLYLCFPENYSVPFWRLRYRFAGKQRSLVIGTYTELSLAKARAKAKEQSARVAL
GYDVAGEKQERKAEALRKMEDEKHALRVSELAAEYFERQILNRWKHPDILRRRIDKDINPAIGRLRIEEVKARDIDDMLQ
KIVQRGAPTVANDVLRWTRRIFDYGIRRHMLETNPTSAFEIDDAGGQEKSRERWLSREELARFLQAMPMTKGFSRQNELT
MKLLLVFCCRKMELCGARWEEFDFNEAVWRLPAERVKNGDAIDIPIPAVALEWLKELHQMSCNSQWVLPARKMQHRMIPH
IQESTLPVALSKVKGNLPDVPNFTIHDFRRTARSHLAALGIDPVVAERCLNHRIKGVEGIYNRYQYFDERKQALELWADL
LVSLERGEGYNVTPLRKGIA
>Mature_419_residues
SKLTDLQIRAWIKSGEHFAGRSDGGGLYLCFPENYSVPFWRLRYRFAGKQRSLVIGTYTELSLAKARAKAKEQSARVALG
YDVAGEKQERKAEALRKMEDEKHALRVSELAAEYFERQILNRWKHPDILRRRIDKDINPAIGRLRIEEVKARDIDDMLQK
IVQRGAPTVANDVLRWTRRIFDYGIRRHMLETNPTSAFEIDDAGGQEKSRERWLSREELARFLQAMPMTKGFSRQNELTM
KLLLVFCCRKMELCGARWEEFDFNEAVWRLPAERVKNGDAIDIPIPAVALEWLKELHQMSCNSQWVLPARKMQHRMIPHI
QESTLPVALSKVKGNLPDVPNFTIHDFRRTARSHLAALGIDPVVAERCLNHRIKGVEGIYNRYQYFDERKQALELWADLL
VSLERGEGYNVTPLRKGIA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=400, Percent_Identity=26.75, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1788974, Length=413, Percent_Identity=26.8765133171913, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788690, Length=382, Percent_Identity=25.9162303664921, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 48742; Mature: 48611

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLTDLQIRAWIKSGEHFAGRSDGGGLYLCFPENYSVPFWRLRYRFAGKQRSLVIGTYT
CCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCEEEECHH
ELSLAKARAKAKEQSARVALGYDVAGEKQERKAEALRKMEDEKHALRVSELAAEYFERQI
HHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNRWKHPDILRRRIDKDINPAIGRLRIEEVKARDIDDMLQKIVQRGAPTVANDVLRWTRR
HHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHH
IFDYGIRRHMLETNPTSAFEIDDAGGQEKSRERWLSREELARFLQAMPMTKGFSRQNELT
HHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHH
MKLLLVFCCRKMELCGARWEEFDFNEAVWRLPAERVKNGDAIDIPIPAVALEWLKELHQM
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHCCCCCEEECCHHHHHHHHHHHHHHH
SCNSQWVLPARKMQHRMIPHIQESTLPVALSKVKGNLPDVPNFTIHDFRRTARSHLAALG
CCCCCCCCCHHHHHHHHCCCHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHC
IDPVVAERCLNHRIKGVEGIYNRYQYFDERKQALELWADLLVSLERGEGYNVTPLRKGIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCC
>Mature Secondary Structure 
SKLTDLQIRAWIKSGEHFAGRSDGGGLYLCFPENYSVPFWRLRYRFAGKQRSLVIGTYT
CCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCEEEECHH
ELSLAKARAKAKEQSARVALGYDVAGEKQERKAEALRKMEDEKHALRVSELAAEYFERQI
HHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNRWKHPDILRRRIDKDINPAIGRLRIEEVKARDIDDMLQKIVQRGAPTVANDVLRWTRR
HHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHH
IFDYGIRRHMLETNPTSAFEIDDAGGQEKSRERWLSREELARFLQAMPMTKGFSRQNELT
HHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHH
MKLLLVFCCRKMELCGARWEEFDFNEAVWRLPAERVKNGDAIDIPIPAVALEWLKELHQM
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHCCCCCEEECCHHHHHHHHHHHHHHH
SCNSQWVLPARKMQHRMIPHIQESTLPVALSKVKGNLPDVPNFTIHDFRRTARSHLAALG
CCCCCCCCCHHHHHHHHCCCHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHC
IDPVVAERCLNHRIKGVEGIYNRYQYFDERKQALELWADLLVSLERGEGYNVTPLRKGIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]