Click here to switch to the map view.

The map label for this gene is ydhC [H]

Identifier: 194736724

GI number: 194736724

Start: 1469587

End: 1470792

Strand: Reverse

Name: ydhC [H]

Synonym: SeSA_A1524

Alternate gene names: 194736724

Gene position: 1470792-1469587 (Counterclockwise)

Preceding gene: 194735272

Following gene: 194736258

Centisome position: 31.23

GC content: 55.31

Gene sequence:

>1206_bases
ATGCAACCTGGAAAAGGTTTTTTAGTCTGGTTAGCCGGCCTTAGCGTGCTGGGGTTTCTGGCTACGGACATGTACCTGCC
CGCGTTTGCCGCCATACAGGCGGATTTACAAACGCCTGCCGCCGCGGTCAGCGCCAGCCTCAGCCTGTTTTTAGCTGGCT
TTGCCGTCGCGCAACTCCTCTGGGGACCGCTATCGGATCGTTATGGCCGTAAACCGATTTTACTGCTGGGGTTATCTATC
TTTGCACTCGGAAGTCTGGGGATGCTGTGGGTAGAAAGCGCGGCAGCACTGCTGACGCTGCGCTTTGTGCAGGCCGTCGG
CGTTTGCGCGGCAACGGTAATCTGGCAAGCGCTGGTGACCGATTATTATCCTTCGCAAAAAATTAACCGTATCTTCGCCA
CGATCATGCCACTGGTGGGATTATCCCCGGCGCTTGCGCCCTTACTGGGAAGCTGGATACTGACGCATTTCTCATGGCAG
GCGATTTTCGCCACCCTGTTCGTGATTACGTTGTTGCTGATGTTGCCGGCGCTGCGCTTAAAACCATCGGTAAAAGCGCG
TACCGAGGGACAGGATAAACTCACTTTCGCGACGTTGTTACGCTCTAAAACCTATCGCGGTAATGTGCTGATTTATGCCG
CCTGTTCCGCCAGCTTTTTTGCGTGGCTAACAGGGTCGCCGTTTATTCTCAGCGCGATGGGTTACAGCCCGGCAGTGATT
GGCCTGAGCTATGTTCCGCAAACCATCGCTTTTCTGATTGGCGGATATGGTTGCCGCGCGGCGCTACAAAAATGGCAGGG
CTACCAATTGCTTCCGTGGCTGTTAGGGCTGTACGCGCTGAGCGTTATCGCCACCTGGGGAGCGGGCCTTCTGAATAATG
CCTCACTGGTGGAGATCCTGATTCCTTTCTGCGTAATGGCGATTGCTAATGGCGCCATCTACCCTATCGTCGTCGCGCAA
GCGTTACGCCCTTTCCCTCAAGCCACTGGGCGCGCTGCGGCGCTACAAAATACGCTGCAGCTGGGGTTATGTTTCCTGGC
AAGCCTGGTGGTTTCATGGCTCATCAGCACGCCGCTACTGACTACCACCAGCGTAATGCTCTCTACCGTTGTTCTGGCGG
CGTTAGGTTACAAAATGCAGTCTCATGCAGAGTGCGCTGAGGCCGAATTTCACCATGCCAATGTCGCCCACGACAAGTCT
CACTAA

Upstream 100 bases:

>100_bases
AAAATTTTGAATTCACTGGACAAATATTAACGTTTCACAACCGTAATTTCACTCCCTACACTCTGCGACAATGTCTGTCT
GATAAGAAAGAGAAACAAAT

Downstream 100 bases:

>100_bases
AAGCTTGTTAACCGCTGGTAATTAGCACGCTAACAATTTTCGGTTGAATCATCAAAAATTGCGGCCTATACTGATTCACG
GTTGTTTATATTACGATAAT

Product: inner membrane transport protein YdhC

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MQPGKGFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPAAAVSASLSLFLAGFAVAQLLWGPLSDRYGRKPILLLGLSI
FALGSLGMLWVESAAALLTLRFVQAVGVCAATVIWQALVTDYYPSQKINRIFATIMPLVGLSPALAPLLGSWILTHFSWQ
AIFATLFVITLLLMLPALRLKPSVKARTEGQDKLTFATLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSAMGYSPAVI
GLSYVPQTIAFLIGGYGCRAALQKWQGYQLLPWLLGLYALSVIATWGAGLLNNASLVEILIPFCVMAIANGAIYPIVVAQ
ALRPFPQATGRAAALQNTLQLGLCFLASLVVSWLISTPLLTTTSVMLSTVVLAALGYKMQSHAECAEAEFHHANVAHDKS
H

Sequences:

>Translated_401_residues
MQPGKGFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPAAAVSASLSLFLAGFAVAQLLWGPLSDRYGRKPILLLGLSI
FALGSLGMLWVESAAALLTLRFVQAVGVCAATVIWQALVTDYYPSQKINRIFATIMPLVGLSPALAPLLGSWILTHFSWQ
AIFATLFVITLLLMLPALRLKPSVKARTEGQDKLTFATLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSAMGYSPAVI
GLSYVPQTIAFLIGGYGCRAALQKWQGYQLLPWLLGLYALSVIATWGAGLLNNASLVEILIPFCVMAIANGAIYPIVVAQ
ALRPFPQATGRAAALQNTLQLGLCFLASLVVSWLISTPLLTTTSVMLSTVVLAALGYKMQSHAECAEAEFHHANVAHDKS
H
>Mature_401_residues
MQPGKGFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPAAAVSASLSLFLAGFAVAQLLWGPLSDRYGRKPILLLGLSI
FALGSLGMLWVESAAALLTLRFVQAVGVCAATVIWQALVTDYYPSQKINRIFATIMPLVGLSPALAPLLGSWILTHFSWQ
AIFATLFVITLLLMLPALRLKPSVKARTEGQDKLTFATLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSAMGYSPAVI
GLSYVPQTIAFLIGGYGCRAALQKWQGYQLLPWLLGLYALSVIATWGAGLLNNASLVEILIPFCVMAIANGAIYPIVVAQ
ALRPFPQATGRAAALQNTLQLGLCFLASLVVSWLISTPLLTTTSVMLSTVVLAALGYKMQSHAECAEAEFHHANVAHDKS
H

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=403, Percent_Identity=85.3598014888337, Blast_Score=675, Evalue=0.0,
Organism=Escherichia coli, GI1788509, Length=344, Percent_Identity=28.7790697674419, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082312, Length=346, Percent_Identity=27.4566473988439, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790146, Length=217, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790794, Length=223, Percent_Identity=26.457399103139, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787065, Length=220, Percent_Identity=24.5454545454545, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319657, Length=163, Percent_Identity=27.6073619631902, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324264, Length=179, Percent_Identity=23.463687150838, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42939; Mature: 42939

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPGKGFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPAAAVSASLSLFLAGFAVAQLL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
WGPLSDRYGRKPILLLGLSIFALGSLGMLWVESAAALLTLRFVQAVGVCAATVIWQALVT
HCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DYYPSQKINRIFATIMPLVGLSPALAPLLGSWILTHFSWQAIFATLFVITLLLMLPALRL
HCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KPSVKARTEGQDKLTFATLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSAMGYSPAVI
CCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCCCHHHHHCCCCCHHH
GLSYVPQTIAFLIGGYGCRAALQKWQGYQLLPWLLGLYALSVIATWGAGLLNNASLVEIL
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IPFCVMAIANGAIYPIVVAQALRPFPQATGRAAALQNTLQLGLCFLASLVVSWLISTPLL
HHHHHHHHHCCCHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
TTTSVMLSTVVLAALGYKMQSHAECAEAEFHHANVAHDKSH
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]