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The map label for this gene is dmsB_2 [H]

Identifier: 194736681

GI number: 194736681

Start: 1541252

End: 1541869

Strand: Reverse

Name: dmsB_2 [H]

Synonym: SeSA_A1599

Alternate gene names: 194736681

Gene position: 1541869-1541252 (Counterclockwise)

Preceding gene: 194737575

Following gene: 194736210

Centisome position: 32.74

GC content: 56.47

Gene sequence:

>618_bases
ATGACAACCCAGTATGGATTTTTTATTGATTCCAGTCGTTGCACCGGTTGCAAAACCTGCGAACTGGCCTGCAAGGACTA
CAAAGATCTCACTCCCGACGTTAGTTTCCGGCGGATATATGAATACGCAGGCGGCGACTGGCAGGAAGATAACGGCGTCT
GGCACCAGAACGTCTTTGCCTACTATCTCTCCATCTCCTGTAACCACTGCGAAGACCCGGCCTGTACGAAAGTCTGCCCG
AGCGGCGCGATGCACAAGCGCGATGACGGTTTTGTGGTGGTGAATGAAGAGGTCTGTATCGGCTGCCGCTACTGCCACAT
GGCCTGCCCGTACGGCGCGCCGCAGTACAACGCCGCCAAAGGTCATATGACCAAGTGCGACGGCTGTTATGACCGGGTGG
CGAAAGGCAAGAAACCAATTTGCGTGGAATCCTGTCCGCTGCGGGCGCTGGACTTTGGTCCGATAGACGAACTGCGCAAA
AAACACGGTGAGCTGGCTGCCGTCGCGCCGCTGCCGCGCGCGCATTTCACGAAGCCGAATATTGTGATTAAACCCAACGC
CAACAGCCGCCCGACCGGGGACACTACCGGTTATCTGGCCAATCCGAAGGAGGTATAA

Upstream 100 bases:

>100_bases
TCCATTAACATTCTGACGTCGCACCGGCCTTCCCCACTGGCGAAAGGTAATCCGTCACACAGTAATCTTGTTCAGGTTGA
AAAGGCGTAAGGAGTAACCC

Downstream 100 bases:

>100_bases
GATGGGAAGTGGATGGCATGAATGGCCGTTGATGATCTTCACGGTCTTTGGTCAGTGCGTGGTCGGCGCGTTAATCGTTA
GCGGACTGGGCTGGCTGACG

Product: dimethylsulfoxide reductase, B subunit

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPDVSFRRIYEYAGGDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCP
SGAMHKRDDGFVVVNEEVCIGCRYCHMACPYGAPQYNAAKGHMTKCDGCYDRVAKGKKPICVESCPLRALDFGPIDELRK
KHGELAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV

Sequences:

>Translated_205_residues
MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPDVSFRRIYEYAGGDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCP
SGAMHKRDDGFVVVNEEVCIGCRYCHMACPYGAPQYNAAKGHMTKCDGCYDRVAKGKKPICVESCPLRALDFGPIDELRK
KHGELAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV
>Mature_204_residues
TTQYGFFIDSSRCTGCKTCELACKDYKDLTPDVSFRRIYEYAGGDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPS
GAMHKRDDGFVVVNEEVCIGCRYCHMACPYGAPQYNAAKGHMTKCDGCYDRVAKGKKPICVESCPLRALDFGPIDELRKK
HGELAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=205, Percent_Identity=96.0975609756098, Blast_Score=417, Evalue=1e-118,
Organism=Escherichia coli, GI1787872, Length=205, Percent_Identity=92.1951219512195, Blast_Score=405, Evalue=1e-115,
Organism=Escherichia coli, GI1787749, Length=164, Percent_Identity=35.3658536585366, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI226510944, Length=155, Percent_Identity=38.7096774193548, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1790326, Length=169, Percent_Identity=31.9526627218935, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1789370, Length=198, Percent_Identity=32.8282828282828, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI2367345, Length=188, Percent_Identity=33.5106382978723, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI2367245, Length=163, Percent_Identity=31.9018404907975, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789067, Length=180, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1787478, Length=99, Percent_Identity=40.4040404040404, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1787740, Length=101, Percent_Identity=38.6138613861386, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI87082179, Length=162, Percent_Identity=30.8641975308642, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788811, Length=158, Percent_Identity=32.9113924050633, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI87082114, Length=188, Percent_Identity=29.2553191489362, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1787963, Length=162, Percent_Identity=27.1604938271605, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789079, Length=111, Percent_Identity=34.2342342342342, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI87082180, Length=153, Percent_Identity=27.4509803921569, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 22779; Mature: 22648

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
9.8 %Cys+Met (Translated Protein)
7.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
9.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPDVSFRRIYEYAGGDWQEDNGVWHQNVFA
CCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHCEEE
YYLSISCNHCEDPACTKVCPSGAMHKRDDGFVVVNEEVCIGCRYCHMACPYGAPQYNAAK
EEEEEECCCCCCCCHHHCCCCCCCCCCCCCEEEECCCEEEEEEEHEEECCCCCCCCCCCC
GHMTKCDGCYDRVAKGKKPICVESCPLRALDFGPIDELRKKHGELAAVAPLPRAHFTKPN
CCCCCCCHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCCCCCCC
IVIKPNANSRPTGDTTGYLANPKEV
EEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTQYGFFIDSSRCTGCKTCELACKDYKDLTPDVSFRRIYEYAGGDWQEDNGVWHQNVFA
CCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHCEEE
YYLSISCNHCEDPACTKVCPSGAMHKRDDGFVVVNEEVCIGCRYCHMACPYGAPQYNAAK
EEEEEECCCCCCCCHHHCCCCCCCCCCCCCEEEECCCEEEEEEEHEEECCCCCCCCCCCC
GHMTKCDGCYDRVAKGKKPICVESCPLRALDFGPIDELRKKHGELAAVAPLPRAHFTKPN
CCCCCCCHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCCCCCCC
IVIKPNANSRPTGDTTGYLANPKEV
EEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 2174699; 1653010 [H]