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The map label for this gene is yfeA [H]

Identifier: 194736553

GI number: 194736553

Start: 2529240

End: 2531429

Strand: Reverse

Name: yfeA [H]

Synonym: SeSA_A2644

Alternate gene names: 194736553

Gene position: 2531429-2529240 (Counterclockwise)

Preceding gene: 194736951

Following gene: 194735091

Centisome position: 53.76

GC content: 50.96

Gene sequence:

>2190_bases
ATGCCGGATAAGTGTAACGTATTAAAAAATATAAAAATATTTTTACTGGCTTTCTGCCTGACCGTTCCGGCTATTCTGCT
ATCTCGTCTCATTTCTCCCCGCGCCACAATTGATTCCAGCTATATCTTTCTGGCCTGGCTACCGCTCTGCGTCATGTTTT
CCGTGCTGTTCTTATTTGGCCGCCGTGGCGTCGCGCCGATGGTAGGCGGAATGATGTTGACTAATGAATGGAATTTTCAT
TTACCTCTGCCACAGGCGATGGTGCTGCTATTTTGCCAGACGTTTCCCGTGTTGCTGGTTTGCGCTATCGTTCGCTGGCA
GCTGGGCGCGCGCTGGCGCTACGGAATACCCAACCAAGGCATCTGGCTACGCGTTTTCTGGTTAGGGTTAATGACGCCGT
TTGGCATAAAAATCAGTATGCATCTGGCGGGGCACTACCTGGCTTTCCCGGTGACAATCTCTACCTTCTTTGGCACCGGC
ACCGCTATTTTCTCGATTGTCGATTTATTGAGTCTGATTTCTGCCGCGCTTATTTTTACCCTCTTTTTCTATTATCCGCT
GCGGATGATAGTCAGCCCGCACTATATTCGTATTTTCTGGCGGAGGGATATCGCTCCTTATCTCGCCAAAGAAAAACGCC
TGTTTACGCTTCTCTGGTTTGCCACTCTGGCGACGCTATTAGCGGTGCTGTGTACGCCTTTCGAGACAAAGTATATTGCT
GGCTATCTGGTGCCAGTCCTGTTCATTGGATTTACCATCGGCGTGGGGAAAATCAGTTATCCGCTGTTGAATTTTAGTTG
GGCTCTCACTGCGCTATTCCTGCTTAGCTATAACCGCAATTTTCTGCAGGGCGTGGGCTCAGAATATTCGCTGGCATTTA
TCCTTTCAGTTCTCATTTCTTTTAGTATTTGTTTGTTGTACATGGCGCGGATTAATCAGCGTAGCGAATGGTTGAATCGA
CAATGGCACTCGCAGGCGTTGACCGATCCGTTGACGCAGCTGCCTAACCTGCGTGCGCTGGAGCAGTTTCTTTTACAGGA
TGCCGGGCAAAGCGTGTGTTATTTACGCATGGAAAACCTGGAATTTCTGAGCCGTCATTACGGTATGCAGATGCGCGTGC
ATTGCGAACGCGAGGTGTTTCGCGTGTTGCAGCCGCTGCTGCTGGAAAAGGAGAAAATTTTCCATCTGCCGGGCAGTGAG
TTATTGCTGGTATTGACGGGACCGGAGACGGAAGCCCGCCTGCAATATATGCTTAATGTGCTTAATAACCGCAAAATTTA
CTGGAACAATACCGGTCTGGACATGGAATACGGCGCATCGTGGGGAACATTCGATGGTCGCCAGGAAACCTTGCAACCGC
TGTTGGGGCAGTTAAGCTGGCTGGCGGAGCAATCCTGCTCGCACCGTCGGGTGCTTGCACTAACCCAGAGTATTGAAGCC
GCTTCCGGTCAGACGACGGAACGGGTGCTGCGGTTGCAGAAAATCCGTCAGGCGCTGGAACGCGGCGCGCTTGTTTTGTA
TGCGCAACCCATTCGCGACGCGCAGGGAAAAGGGTATGACGAGATTCTGACGCGGCTTCGGTGCGACGACGGTATCATGA
TGCCCAATCAGTTCATTCCGCTTATCGCCCAGTTTAACCTGAGCGTACGGTTTGATATGCAGGTGATGGAAGCGCTCCTG
CAATGGTTGTCCGCGCATCCTTCGGCGGAGCAGGGGGCGCGTTTCTCGGTTAATTTGATGCCGCTGACGCTGCTGCAAAA
AGAGACGGCGTCGCGCATTATGCAGCTTTTTAAACGCTATGGCGTCCCGCCTGCTTCGGTCATCATCGAAATTACTGAAG
AACAGGCCTTCTCTCATTCCGAAATCAGTATGCACAATATCAACCAGCTGCGTAAGTTTGGCCTAAAAATCGCCATTGAT
GATTTCGGCACCGGCTATGCAAACTATGAACGGCTAAAACGCCTCAAGGCGGACATCATTAAAATCGACGGCTGTTTCGT
GAAAGATATTCTGACGGACTCCCTGGATGCGATGATCGTGAAATCCATCACTGATTTAGCGAAAGCGAAATCGTTGAGCG
TCGTGGCTGAGTTTGTTGAAACGCCTGCGCAGCGCGATCTGCTATTGCAGCTTGGCGTACACAGTTTGCAGGGATATCTG
ATTGGCCGCCCGCGCCCGTTAGGCAAATAA

Upstream 100 bases:

>100_bases
CGCTGCTTTTGCGGTCAATATGAGCTTTTGTTAGATTGCTTCATAATGCGAATATACTTATTATTCATGCGCCTTATATA
ATGATGTGAGCATTAAAGCA

Downstream 100 bases:

>100_bases
GCGGCATAAAAAAAACCGGGGATAGCTCCCCGGTTTTTACATTAAACGCAGACTTACAGTACCAGCGCCGCGATAGAGGC
GGACAGTACGCTCACCAGCG

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 729; Mature: 728

Protein sequence:

>729_residues
MPDKCNVLKNIKIFLLAFCLTVPAILLSRLISPRATIDSSYIFLAWLPLCVMFSVLFLFGRRGVAPMVGGMMLTNEWNFH
LPLPQAMVLLFCQTFPVLLVCAIVRWQLGARWRYGIPNQGIWLRVFWLGLMTPFGIKISMHLAGHYLAFPVTISTFFGTG
TAIFSIVDLLSLISAALIFTLFFYYPLRMIVSPHYIRIFWRRDIAPYLAKEKRLFTLLWFATLATLLAVLCTPFETKYIA
GYLVPVLFIGFTIGVGKISYPLLNFSWALTALFLLSYNRNFLQGVGSEYSLAFILSVLISFSICLLYMARINQRSEWLNR
QWHSQALTDPLTQLPNLRALEQFLLQDAGQSVCYLRMENLEFLSRHYGMQMRVHCEREVFRVLQPLLLEKEKIFHLPGSE
LLLVLTGPETEARLQYMLNVLNNRKIYWNNTGLDMEYGASWGTFDGRQETLQPLLGQLSWLAEQSCSHRRVLALTQSIEA
ASGQTTERVLRLQKIRQALERGALVLYAQPIRDAQGKGYDEILTRLRCDDGIMMPNQFIPLIAQFNLSVRFDMQVMEALL
QWLSAHPSAEQGARFSVNLMPLTLLQKETASRIMQLFKRYGVPPASVIIEITEEQAFSHSEISMHNINQLRKFGLKIAID
DFGTGYANYERLKRLKADIIKIDGCFVKDILTDSLDAMIVKSITDLAKAKSLSVVAEFVETPAQRDLLLQLGVHSLQGYL
IGRPRPLGK

Sequences:

>Translated_729_residues
MPDKCNVLKNIKIFLLAFCLTVPAILLSRLISPRATIDSSYIFLAWLPLCVMFSVLFLFGRRGVAPMVGGMMLTNEWNFH
LPLPQAMVLLFCQTFPVLLVCAIVRWQLGARWRYGIPNQGIWLRVFWLGLMTPFGIKISMHLAGHYLAFPVTISTFFGTG
TAIFSIVDLLSLISAALIFTLFFYYPLRMIVSPHYIRIFWRRDIAPYLAKEKRLFTLLWFATLATLLAVLCTPFETKYIA
GYLVPVLFIGFTIGVGKISYPLLNFSWALTALFLLSYNRNFLQGVGSEYSLAFILSVLISFSICLLYMARINQRSEWLNR
QWHSQALTDPLTQLPNLRALEQFLLQDAGQSVCYLRMENLEFLSRHYGMQMRVHCEREVFRVLQPLLLEKEKIFHLPGSE
LLLVLTGPETEARLQYMLNVLNNRKIYWNNTGLDMEYGASWGTFDGRQETLQPLLGQLSWLAEQSCSHRRVLALTQSIEA
ASGQTTERVLRLQKIRQALERGALVLYAQPIRDAQGKGYDEILTRLRCDDGIMMPNQFIPLIAQFNLSVRFDMQVMEALL
QWLSAHPSAEQGARFSVNLMPLTLLQKETASRIMQLFKRYGVPPASVIIEITEEQAFSHSEISMHNINQLRKFGLKIAID
DFGTGYANYERLKRLKADIIKIDGCFVKDILTDSLDAMIVKSITDLAKAKSLSVVAEFVETPAQRDLLLQLGVHSLQGYL
IGRPRPLGK
>Mature_728_residues
PDKCNVLKNIKIFLLAFCLTVPAILLSRLISPRATIDSSYIFLAWLPLCVMFSVLFLFGRRGVAPMVGGMMLTNEWNFHL
PLPQAMVLLFCQTFPVLLVCAIVRWQLGARWRYGIPNQGIWLRVFWLGLMTPFGIKISMHLAGHYLAFPVTISTFFGTGT
AIFSIVDLLSLISAALIFTLFFYYPLRMIVSPHYIRIFWRRDIAPYLAKEKRLFTLLWFATLATLLAVLCTPFETKYIAG
YLVPVLFIGFTIGVGKISYPLLNFSWALTALFLLSYNRNFLQGVGSEYSLAFILSVLISFSICLLYMARINQRSEWLNRQ
WHSQALTDPLTQLPNLRALEQFLLQDAGQSVCYLRMENLEFLSRHYGMQMRVHCEREVFRVLQPLLLEKEKIFHLPGSEL
LLVLTGPETEARLQYMLNVLNNRKIYWNNTGLDMEYGASWGTFDGRQETLQPLLGQLSWLAEQSCSHRRVLALTQSIEAA
SGQTTERVLRLQKIRQALERGALVLYAQPIRDAQGKGYDEILTRLRCDDGIMMPNQFIPLIAQFNLSVRFDMQVMEALLQ
WLSAHPSAEQGARFSVNLMPLTLLQKETASRIMQLFKRYGVPPASVIIEITEEQAFSHSEISMHNINQLRKFGLKIAIDD
FGTGYANYERLKRLKADIIKIDGCFVKDILTDSLDAMIVKSITDLAKAKSLSVVAEFVETPAQRDLLLQLGVHSLQGYLI
GRPRPLGK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87082096, Length=724, Percent_Identity=68.646408839779, Blast_Score=1025, Evalue=0.0,
Organism=Escherichia coli, GI1788849, Length=717, Percent_Identity=28.3124128312413, Blast_Score=285, Evalue=6e-78,
Organism=Escherichia coli, GI226510982, Length=258, Percent_Identity=32.9457364341085, Blast_Score=116, Evalue=6e-27,
Organism=Escherichia coli, GI1790496, Length=237, Percent_Identity=32.9113924050633, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787055, Length=329, Percent_Identity=28.2674772036474, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI87081743, Length=245, Percent_Identity=31.8367346938775, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1787541, Length=421, Percent_Identity=24.4655581947743, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1786507, Length=263, Percent_Identity=30.0380228136882, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI87081845, Length=235, Percent_Identity=29.7872340425532, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI1788502, Length=244, Percent_Identity=30.7377049180328, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87081980, Length=238, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI87081921, Length=256, Percent_Identity=29.6875, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787410, Length=151, Percent_Identity=28.476821192053, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1789650, Length=234, Percent_Identity=22.6495726495727, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895 [H]

Pfam domain/function: PF00563 EAL; PF05231 MASE1 [H]

EC number: NA

Molecular weight: Translated: 83147; Mature: 83016

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDKCNVLKNIKIFLLAFCLTVPAILLSRLISPRATIDSSYIFLAWLPLCVMFSVLFLFG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
RRGVAPMVGGMMLTNEWNFHLPLPQAMVLLFCQTFPVLLVCAIVRWQLGARWRYGIPNQG
CCCCCHHHCCEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
IWLRVFWLGLMTPFGIKISMHLAGHYLAFPVTISTFFGTGTAIFSIVDLLSLISAALIFT
HHHHHHHHHHCCCCCEEEEEEECCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LFFYYPLRMIVSPHYIRIFWRRDIAPYLAKEKRLFTLLWFATLATLLAVLCTPFETKYIA
HHHHHHHHHHHCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GYLVPVLFIGFTIGVGKISYPLLNFSWALTALFLLSYNRNFLQGVGSEYSLAFILSVLIS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHH
FSICLLYMARINQRSEWLNRQWHSQALTDPLTQLPNLRALEQFLLQDAGQSVCYLRMENL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEHHHH
EFLSRHYGMQMRVHCEREVFRVLQPLLLEKEKIFHLPGSELLLVLTGPETEARLQYMLNV
HHHHHHCCCEEEEHHHHHHHHHHHHHHHCHHHHEECCCCCEEEEEECCCHHHHHHHHHHH
LNNRKIYWNNTGLDMEYGASWGTFDGRQETLQPLLGQLSWLAEQSCSHRRVLALTQSIEA
HCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ASGQTTERVLRLQKIRQALERGALVLYAQPIRDAQGKGYDEILTRLRCDDGIMMPNQFIP
CCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHH
LIAQFNLSVRFDMQVMEALLQWLSAHPSAEQGARFSVNLMPLTLLQKETASRIMQLFKRY
HHHHCCCEEEECHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
GVPPASVIIEITEEQAFSHSEISMHNINQLRKFGLKIAIDDFGTGYANYERLKRLKADII
CCCHHHEEEEEHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHE
KIDGCFVKDILTDSLDAMIVKSITDLAKAKSLSVVAEFVETPAQRDLLLQLGVHSLQGYL
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEE
IGRPRPLGK
ECCCCCCCC
>Mature Secondary Structure 
PDKCNVLKNIKIFLLAFCLTVPAILLSRLISPRATIDSSYIFLAWLPLCVMFSVLFLFG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
RRGVAPMVGGMMLTNEWNFHLPLPQAMVLLFCQTFPVLLVCAIVRWQLGARWRYGIPNQG
CCCCCHHHCCEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
IWLRVFWLGLMTPFGIKISMHLAGHYLAFPVTISTFFGTGTAIFSIVDLLSLISAALIFT
HHHHHHHHHHCCCCCEEEEEEECCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LFFYYPLRMIVSPHYIRIFWRRDIAPYLAKEKRLFTLLWFATLATLLAVLCTPFETKYIA
HHHHHHHHHHHCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GYLVPVLFIGFTIGVGKISYPLLNFSWALTALFLLSYNRNFLQGVGSEYSLAFILSVLIS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHH
FSICLLYMARINQRSEWLNRQWHSQALTDPLTQLPNLRALEQFLLQDAGQSVCYLRMENL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEHHHH
EFLSRHYGMQMRVHCEREVFRVLQPLLLEKEKIFHLPGSELLLVLTGPETEARLQYMLNV
HHHHHHCCCEEEEHHHHHHHHHHHHHHHCHHHHEECCCCCEEEEEECCCHHHHHHHHHHH
LNNRKIYWNNTGLDMEYGASWGTFDGRQETLQPLLGQLSWLAEQSCSHRRVLALTQSIEA
HCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ASGQTTERVLRLQKIRQALERGALVLYAQPIRDAQGKGYDEILTRLRCDDGIMMPNQFIP
CCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHH
LIAQFNLSVRFDMQVMEALLQWLSAHPSAEQGARFSVNLMPLTLLQKETASRIMQLFKRY
HHHHCCCEEEECHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
GVPPASVIIEITEEQAFSHSEISMHNINQLRKFGLKIAIDDFGTGYANYERLKRLKADII
CCCHHHEEEEEHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHE
KIDGCFVKDILTDSLDAMIVKSITDLAKAKSLSVVAEFVETPAQRDLLLQLGVHSLQGYL
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEE
IGRPRPLGK
ECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 2201776 [H]