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The map label for this gene is oadA [H]

Identifier: 194736505

GI number: 194736505

Start: 64866

End: 66635

Strand: Reverse

Name: oadA [H]

Synonym: SeSA_A0061

Alternate gene names: 194736505

Gene position: 66635-64866 (Counterclockwise)

Preceding gene: 194738402

Following gene: 194737067

Centisome position: 1.42

GC content: 63.39

Gene sequence:

>1770_bases
ATGACTATTGCCATTACCGATGTCGTCCTGCGCGACGCCCACCAGTCCCTGTTCGCCACCCGTCTGCGTCTTGATGATAT
GCTGCCCATTGCCGCCGCGCTCGATAACGTGGGCTACGGCTCCCTCGAATGCTGGGGCGGCGCCACCTTTGACGCCTGCA
TTCGCTTTCTCGGCGAAGACCCGTGGCTGCGCCTGCGCGAACTCAAAAAAGCCATGCCCAAAACCCCGCTGCAGATGCTG
CTGCGTGGCCAGAACCTGCTCGGCTACCGCCACTACGCCGATGACGTGGTGGAGCGTTTTGTCGAACGCGCGGTGAAAAA
CGGCATGGACGTGTTCCGCGTGTTTGATGCCATGAACGACCCGCGCAATATGAAAGCCGCCCTGCAGGCGGTGCGCAGCC
ACGGCGCACACGCCCAGGGCACGCTCTCTTACACCACCAGCCCGGCGCACACCCTGCAGACCTGGCTGGATTTAACGGAG
CAACTGCTGGAAACCGGCGTTGACTCGATTGCCATCAAGGATATGTCCGGCATCCTGACGCCGATGGTCGCCTTTGAGCT
GGTCAGTGAAATCAAAAAACGTTTTGAGGTGCGCCTGCACCTGCACTGTCACGCCACCACCGGGATGGCGGAGATGGCGC
TGCTGAAGGCCATCGAGGCGGGCGTTGACGGCGTCGACACGGCGATTTCCTCCATGAGCGCCACCTACGGCCACCCGGCC
ACCGAGGCGCTGGTGGCGACGTTGGCAGGTACTGAGCACGACACCGGGCTGGATATCCTGAAACTGGAAAACATCGCCGC
GTACTTCCGCGAGGTGCGCAAGAAATACCACGCCTTTGAAGGCCAGCTGAAGGGCTACGACAGCCGCATTCTGGTGGCGC
AGGTGCCGGGCGGAATGCTGACCAACCTCGAAAGCCAGCTGAAGCAGCAGAACGCGGCGGACAAACTCGACCAGGTGCTG
GCGGAAATCCCCCGCGTGCGCGAGGACCTCGGTTTTATCCCGCTGGTGACCCCCACCTCGCAGATTGTCGGCACCCAGGC
GGTGCTCAACGTCCTGACCGGCGAACGCTACAAAACCATTGCCAAAGAAACGGCGGGCATTCTGAAAGGCGAATACGGCC
ACACCCCGGTGCCGGTTAACGCCGCGTTACAGGCCCGCGTGCTGGAAGGGGCAGCCCCGGTGACCTGCCGTCCGGCGGAT
TTACTCAAACCGGAACTGGCTGAACTGGAAGCGGACGTCAGGCGCCAGGCGCAGGAGAAGGGCATCCAGCTTGCGGGAAA
CGCCATCGACGACGTGCTCACCGTGGCGCTGTTCCCGCAAATCGGCCTCAAATTCCTTGAGAACCGCCACAACCCGGCGG
CGTTTGAGCCACTGCCGCAGGCGGAAGCCGCGCAGCCGGTGGCAAAAGCAGAGAAGCCTGCCGCCTCCGGTATCTACACC
GTGGAAGTGGAAGGCAAAGCCTTTGTGGTGAAGGTCAGCGACGGCGGCGATATCAGCCAGCTCACTGCTGCCACCCCGTC
TTCCGCACCGGTTCAGGCAGCCGCCCCGGCAGGCGCAGGCACCCCGGTCACCGCCCCGCTGGCGGGCAACATCTGGAAGG
TGATTGCCACCGAGGGCCAGACGGTGGCCGAAGGCGATGTGCTGCTGATTCTGGAGGCCATGAAGATGGAAACCGAAATC
CGCGCCGCGCAGGCCGGGACGGTACGCGGTATTGCGGTGAAGTCCGGGGACGCGGTTTCCGTCGGCGACACCCTGATGAC
GCTGGCGTAA

Upstream 100 bases:

>100_bases
GCGCGCCGTTCCCGTCGTGGACGACTTCACCCGCTTAAAGCCGGTGATTGCCGCCGCCATTCACCATCACCGCCTTAACG
CTTAATTCCCGGAGGGATCC

Downstream 100 bases:

>100_bases
CGGAGAACTGAAATGGAAAGTCTGAACGCCCTGCTTCAGGGCATGGGGCTGATGCACCTTGGCGCGGGCCAGGCCATCAT
GCTGCTGGTCAGCCTGCTGT

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 588

Protein sequence:

>589_residues
MTIAITDVVLRDAHQSLFATRLRLDDMLPIAAALDNVGYGSLECWGGATFDACIRFLGEDPWLRLRELKKAMPKTPLQML
LRGQNLLGYRHYADDVVERFVERAVKNGMDVFRVFDAMNDPRNMKAALQAVRSHGAHAQGTLSYTTSPAHTLQTWLDLTE
QLLETGVDSIAIKDMSGILTPMVAFELVSEIKKRFEVRLHLHCHATTGMAEMALLKAIEAGVDGVDTAISSMSATYGHPA
TEALVATLAGTEHDTGLDILKLENIAAYFREVRKKYHAFEGQLKGYDSRILVAQVPGGMLTNLESQLKQQNAADKLDQVL
AEIPRVREDLGFIPLVTPTSQIVGTQAVLNVLTGERYKTIAKETAGILKGEYGHTPVPVNAALQARVLEGAAPVTCRPAD
LLKPELAELEADVRRQAQEKGIQLAGNAIDDVLTVALFPQIGLKFLENRHNPAAFEPLPQAEAAQPVAKAEKPAASGIYT
VEVEGKAFVVKVSDGGDISQLTAATPSSAPVQAAAPAGAGTPVTAPLAGNIWKVIATEGQTVAEGDVLLILEAMKMETEI
RAAQAGTVRGIAVKSGDAVSVGDTLMTLA

Sequences:

>Translated_589_residues
MTIAITDVVLRDAHQSLFATRLRLDDMLPIAAALDNVGYGSLECWGGATFDACIRFLGEDPWLRLRELKKAMPKTPLQML
LRGQNLLGYRHYADDVVERFVERAVKNGMDVFRVFDAMNDPRNMKAALQAVRSHGAHAQGTLSYTTSPAHTLQTWLDLTE
QLLETGVDSIAIKDMSGILTPMVAFELVSEIKKRFEVRLHLHCHATTGMAEMALLKAIEAGVDGVDTAISSMSATYGHPA
TEALVATLAGTEHDTGLDILKLENIAAYFREVRKKYHAFEGQLKGYDSRILVAQVPGGMLTNLESQLKQQNAADKLDQVL
AEIPRVREDLGFIPLVTPTSQIVGTQAVLNVLTGERYKTIAKETAGILKGEYGHTPVPVNAALQARVLEGAAPVTCRPAD
LLKPELAELEADVRRQAQEKGIQLAGNAIDDVLTVALFPQIGLKFLENRHNPAAFEPLPQAEAAQPVAKAEKPAASGIYT
VEVEGKAFVVKVSDGGDISQLTAATPSSAPVQAAAPAGAGTPVTAPLAGNIWKVIATEGQTVAEGDVLLILEAMKMETEI
RAAQAGTVRGIAVKSGDAVSVGDTLMTLA
>Mature_588_residues
TIAITDVVLRDAHQSLFATRLRLDDMLPIAAALDNVGYGSLECWGGATFDACIRFLGEDPWLRLRELKKAMPKTPLQMLL
RGQNLLGYRHYADDVVERFVERAVKNGMDVFRVFDAMNDPRNMKAALQAVRSHGAHAQGTLSYTTSPAHTLQTWLDLTEQ
LLETGVDSIAIKDMSGILTPMVAFELVSEIKKRFEVRLHLHCHATTGMAEMALLKAIEAGVDGVDTAISSMSATYGHPAT
EALVATLAGTEHDTGLDILKLENIAAYFREVRKKYHAFEGQLKGYDSRILVAQVPGGMLTNLESQLKQQNAADKLDQVLA
EIPRVREDLGFIPLVTPTSQIVGTQAVLNVLTGERYKTIAKETAGILKGEYGHTPVPVNAALQARVLEGAAPVTCRPADL
LKPELAELEADVRRQAQEKGIQLAGNAIDDVLTVALFPQIGLKFLENRHNPAAFEPLPQAEAAQPVAKAEKPAASGIYTV
EVEGKAFVVKVSDGGDISQLTAATPSSAPVQAAAPAGAGTPVTAPLAGNIWKVIATEGQTVAEGDVLLILEAMKMETEIR
AAQAGTVRGIAVKSGDAVSVGDTLMTLA

Specific function: Lyase and sodium transporter [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=628, Percent_Identity=33.1210191082803, Blast_Score=280, Evalue=3e-75,
Organism=Homo sapiens, GI106049295, Length=628, Percent_Identity=33.1210191082803, Blast_Score=280, Evalue=3e-75,
Organism=Homo sapiens, GI106049292, Length=628, Percent_Identity=33.1210191082803, Blast_Score=280, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI17562816, Length=626, Percent_Identity=33.7060702875399, Blast_Score=307, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6319695, Length=629, Percent_Identity=32.2734499205087, Blast_Score=302, Evalue=8e-83,
Organism=Saccharomyces cerevisiae, GI6321376, Length=629, Percent_Identity=31.4785373608903, Blast_Score=292, Evalue=9e-80,
Organism=Drosophila melanogaster, GI24652212, Length=634, Percent_Identity=31.7034700315457, Blast_Score=285, Evalue=9e-77,
Organism=Drosophila melanogaster, GI24652210, Length=634, Percent_Identity=31.7034700315457, Blast_Score=285, Evalue=9e-77,
Organism=Drosophila melanogaster, GI24652214, Length=634, Percent_Identity=31.7034700315457, Blast_Score=285, Evalue=9e-77,
Organism=Drosophila melanogaster, GI19921944, Length=634, Percent_Identity=31.7034700315457, Blast_Score=285, Evalue=9e-77,
Organism=Drosophila melanogaster, GI24652216, Length=634, Percent_Identity=31.7034700315457, Blast_Score=285, Evalue=9e-77,
Organism=Drosophila melanogaster, GI281363050, Length=634, Percent_Identity=31.7034700315457, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24652224, Length=634, Percent_Identity=31.7034700315457, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24652222, Length=634, Percent_Identity=31.7034700315457, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24652220, Length=634, Percent_Identity=31.7034700315457, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24652218, Length=634, Percent_Identity=31.7034700315457, Blast_Score=284, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR005776
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =4.1.1.3 [H]

Molecular weight: Translated: 63142; Mature: 63011

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAITDVVLRDAHQSLFATRLRLDDMLPIAAALDNVGYGSLECWGGATFDACIRFLGED
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCC
PWLRLRELKKAMPKTPLQMLLRGQNLLGYRHYADDVVERFVERAVKNGMDVFRVFDAMND
CHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
PRNMKAALQAVRSHGAHAQGTLSYTTSPAHTLQTWLDLTEQLLETGVDSIAIKDMSGILT
CHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
PMVAFELVSEIKKRFEVRLHLHCHATTGMAEMALLKAIEAGVDGVDTAISSMSATYGHPA
HHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCH
TEALVATLAGTEHDTGLDILKLENIAAYFREVRKKYHAFEGQLKGYDSRILVAQVPGGML
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHH
TNLESQLKQQNAADKLDQVLAEIPRVREDLGFIPLVTPTSQIVGTQAVLNVLTGERYKTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCHHHHHH
AKETAGILKGEYGHTPVPVNAALQARVLEGAAPVTCRPADLLKPELAELEADVRRQAQEK
HHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHC
GIQLAGNAIDDVLTVALFPQIGLKFLENRHNPAAFEPLPQAEAAQPVAKAEKPAASGIYT
CCEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHCCCCCCCCEEE
VEVEGKAFVVKVSDGGDISQLTAATPSSAPVQAAAPAGAGTPVTAPLAGNIWKVIATEGQ
EEECCEEEEEEECCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEEEECCCC
TVAEGDVLLILEAMKMETEIRAAQAGTVRGIAVKSGDAVSVGDTLMTLA
EEECCCEEEEEHHHHHHHHHHHHHCCCEEEEEEECCCCEECCCHHHHCC
>Mature Secondary Structure 
TIAITDVVLRDAHQSLFATRLRLDDMLPIAAALDNVGYGSLECWGGATFDACIRFLGED
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCC
PWLRLRELKKAMPKTPLQMLLRGQNLLGYRHYADDVVERFVERAVKNGMDVFRVFDAMND
CHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
PRNMKAALQAVRSHGAHAQGTLSYTTSPAHTLQTWLDLTEQLLETGVDSIAIKDMSGILT
CHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
PMVAFELVSEIKKRFEVRLHLHCHATTGMAEMALLKAIEAGVDGVDTAISSMSATYGHPA
HHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCH
TEALVATLAGTEHDTGLDILKLENIAAYFREVRKKYHAFEGQLKGYDSRILVAQVPGGML
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHH
TNLESQLKQQNAADKLDQVLAEIPRVREDLGFIPLVTPTSQIVGTQAVLNVLTGERYKTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCHHHHHH
AKETAGILKGEYGHTPVPVNAALQARVLEGAAPVTCRPADLLKPELAELEADVRRQAQEK
HHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHC
GIQLAGNAIDDVLTVALFPQIGLKFLENRHNPAAFEPLPQAEAAQPVAKAEKPAASGIYT
CCEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHCCCCCCCCEEE
VEVEGKAFVVKVSDGGDISQLTAATPSSAPVQAAAPAGAGTPVTAPLAGNIWKVIATEGQ
EEECCEEEEEEECCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEEEECCCC
TVAEGDVLLILEAMKMETEIRAAQAGTVRGIAVKSGDAVSVGDTLMTLA
EEECCCEEEEEHHHHHHHHHHHHHCCCEEEEEEECCCCEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2454915 [H]