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The map label for this gene is dtpB [H]

Identifier: 194736456

GI number: 194736456

Start: 3645584

End: 3647056

Strand: Direct

Name: dtpB [H]

Synonym: SeSA_A3785

Alternate gene names: 194736456

Gene position: 3645584-3647056 (Clockwise)

Preceding gene: 194737052

Following gene: 194735285

Centisome position: 77.42

GC content: 51.26

Gene sequence:

>1473_bases
ATGAATACAACTGCACCTACGGGCTTGCTGCAGCAACCTCGTCCATTCTTCATGATCTTTTTTGTAGAATTATGGGAACG
ATTTGGCTATTACGGCGTCCAGGGCATCCTGGCGGTCTTTTTCGTTAAACAATTGGGTTTTTCTCAGGAACAGGCCTTTA
TTACCTTTGGCGCTTTTGCGGCGCTGGTTTATGGCCTGATCTCCATCGGCGGCTATGTTGGCGACCATCTGTTAGGGACT
AAACGCACCCTGGTCCTGGGCGCGATTGTGCTGGCGATTGGCTATTTTATGACCGGCATGTCGCTATTAAATCCCGATCT
GATTTTTATCGCACTGGGTACGATTGCCGTGGGCAACGGGTTATTTAAAGCCAATCCCGCCAGCCTGCTCTCTAAATGCT
ATCAGCCTAAAGATCCCCGGCTGGATGGCGCTTTCACCCTGTTTTATATGTCGATTAACATCGGTTCTTTGTTATCGCTA
TCGCTGGCGCCGGTGATTGCCGATAAATTTGGCTATGCGGTGACCTATAATCTGTGCGGCGCTGGTTTAATTGTTGCGCT
TCTGGTGTACTTCGCCTGCCGTGGCATGGTGAAAAATATCGGTTCTGAACCGGATCATAAACCGCTACGTTTTCGCAATT
TGCTGCTGGTACTGCTCGGCACCATCGTCATGATTTTCCTCTGCGCCTGGCTGATGCACAACGTTAAGATTGCCAATCTG
GTGCTCATCATCCTTTCTATCGTCGTCACTATTTTCTTCTTTCGCGAAGCGTTTCGTCTGGATAAAACCGGCCGCAATAA
AATGTTCGTGGCGTTTATTCTGATGATTGAAGCCGTGCTGTTTTACATTCTGTATGCGCAGATGCCTACCTCGCTGAACT
TCTTTGCGATTAATAACGTGCATCATGAAATTCTTGGATTCGCCATTAACCCGGTGAGTTTTCAGGCGCTGAACCCATTC
TGGGTGGTCGTCGCCAGTCCGGTACTGGCAGCGATTTACACCCGACTGGGTAGCAAAGGCAAAGATCTGACTATGCCGAT
GAAGTTTACGCTTGGCATGTTCCTCTGCGCGCTGGGTTTTCTGACCGCCGCCGCCGCCGGGATGTGGTTTGCCGATGCGC
AAGGATTGACGTCGCCGTGGTTTATCGTGCTGGTGTATCTGTTCCAGAGTCTGGGCGAGCTGCTGATTAGCGCGCTGGGG
CTGGCAATGGTCGCCGCTCTGGTGCCGCAGCATCTGATGGGCTTTATTCTGGGAATGTGGTTCCTGACCCAGGCCGCCGC
CTTCCTGCTCGGCGGTTATGTGGCGACCTTCACTGCCGTACCGGAAAACATCACCGATCCGTTGCAGACGCTGCCAATTT
ATACCGGCGTCTTTAGCAAAATTGGTCTGGTAACGCTGGCGGTCACCGTGGTGATGGCCATTATGGTGCCGTGGTTAAAC
CGAATGATTAATACGCCAGATACCGAACAGTAA

Upstream 100 bases:

>100_bases
ATCAGGCTAATAACCGCAGTCTATATCAGGGTAAGTCTTTTCGGCGCGTTTTGATATACGCGCTCATACGTTTCGGGATG
GCATTAAAAGGCGAAGGAAT

Downstream 100 bases:

>100_bases
TACTCAGTGCCGGATGCGGCTTACGCCTTATCCGGCCTACAAATAATTGAGAATCGTAGGCCCGATAAGCGCAACGCCAT
CGGGCAATCCGTTACTCCGT

Product: inner membrane transporter YhiP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MNTTAPTGLLQQPRPFFMIFFVELWERFGYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGT
KRTLVLGAIVLAIGYFMTGMSLLNPDLIFIALGTIAVGNGLFKANPASLLSKCYQPKDPRLDGAFTLFYMSINIGSLLSL
SLAPVIADKFGYAVTYNLCGAGLIVALLVYFACRGMVKNIGSEPDHKPLRFRNLLLVLLGTIVMIFLCAWLMHNVKIANL
VLIILSIVVTIFFFREAFRLDKTGRNKMFVAFILMIEAVLFYILYAQMPTSLNFFAINNVHHEILGFAINPVSFQALNPF
WVVVASPVLAAIYTRLGSKGKDLTMPMKFTLGMFLCALGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLGELLISALG
LAMVAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPENITDPLQTLPIYTGVFSKIGLVTLAVTVVMAIMVPWLN
RMINTPDTEQ

Sequences:

>Translated_490_residues
MNTTAPTGLLQQPRPFFMIFFVELWERFGYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGT
KRTLVLGAIVLAIGYFMTGMSLLNPDLIFIALGTIAVGNGLFKANPASLLSKCYQPKDPRLDGAFTLFYMSINIGSLLSL
SLAPVIADKFGYAVTYNLCGAGLIVALLVYFACRGMVKNIGSEPDHKPLRFRNLLLVLLGTIVMIFLCAWLMHNVKIANL
VLIILSIVVTIFFFREAFRLDKTGRNKMFVAFILMIEAVLFYILYAQMPTSLNFFAINNVHHEILGFAINPVSFQALNPF
WVVVASPVLAAIYTRLGSKGKDLTMPMKFTLGMFLCALGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLGELLISALG
LAMVAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPENITDPLQTLPIYTGVFSKIGLVTLAVTVVMAIMVPWLN
RMINTPDTEQ
>Mature_490_residues
MNTTAPTGLLQQPRPFFMIFFVELWERFGYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGT
KRTLVLGAIVLAIGYFMTGMSLLNPDLIFIALGTIAVGNGLFKANPASLLSKCYQPKDPRLDGAFTLFYMSINIGSLLSL
SLAPVIADKFGYAVTYNLCGAGLIVALLVYFACRGMVKNIGSEPDHKPLRFRNLLLVLLGTIVMIFLCAWLMHNVKIANL
VLIILSIVVTIFFFREAFRLDKTGRNKMFVAFILMIEAVLFYILYAQMPTSLNFFAINNVHHEILGFAINPVSFQALNPF
WVVVASPVLAAIYTRLGSKGKDLTMPMKFTLGMFLCALGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLGELLISALG
LAMVAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPENITDPLQTLPIYTGVFSKIGLVTLAVTVVMAIMVPWLN
RMINTPDTEQ

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=389, Percent_Identity=23.3933161953728, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI226371746, Length=358, Percent_Identity=24.8603351955307, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI226371748, Length=350, Percent_Identity=24.5714285714286, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1789911, Length=489, Percent_Identity=87.7300613496933, Blast_Score=890, Evalue=0.0,
Organism=Escherichia coli, GI1787922, Length=472, Percent_Identity=51.9067796610169, Blast_Score=513, Evalue=1e-146,
Organism=Escherichia coli, GI1786927, Length=438, Percent_Identity=26.9406392694064, Blast_Score=168, Evalue=8e-43,
Organism=Escherichia coli, GI1790572, Length=481, Percent_Identity=26.8191268191268, Blast_Score=161, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17541704, Length=391, Percent_Identity=24.2966751918159, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17569141, Length=202, Percent_Identity=27.7227722772277, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28571098, Length=389, Percent_Identity=22.879177377892, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639583, Length=342, Percent_Identity=24.5614035087719, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28571102, Length=212, Percent_Identity=25.4716981132075, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28571100, Length=212, Percent_Identity=25.4716981132075, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24639585, Length=331, Percent_Identity=24.773413897281, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24639581, Length=331, Percent_Identity=24.773413897281, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53757; Mature: 53757

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCCC
>Mature Secondary Structure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HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]