Click here to switch to the map view.

The map label for this gene is nhaR [H]

Identifier: 194736409

GI number: 194736409

Start: 47417

End: 48316

Strand: Direct

Name: nhaR [H]

Synonym: SeSA_A0045

Alternate gene names: 194736409

Gene position: 47417-48316 (Clockwise)

Preceding gene: 194736826

Following gene: 194734968

Centisome position: 1.01

GC content: 50.56

Gene sequence:

>900_bases
ATGAGCATGTCTCATATTAACTACAACCATCTTTATTACTTCTGGCATGTCTATAAAGAAGGTTCTGTCGTGGGTGCCGC
AGAGGCGCTTTTTCTGACGCCGCAAACCATTACTGGTCAAATTAAAGCCCTGGAAGAGCGTTTACAGGGGAAGCTATTTA
AACGTAAGGGACGCGGTCTTGAGCCCAGCGAACTGGGCGAGCTGGTTTTTCGCTATGCGGATAAAATGTTTACGCTAAGC
CAGGAGATGCTGGATATCGTCAATTACCGCAAAGAATCAAACCTGTTGTTTGATGTCGGCGTCGCCGATGCTTTATCCAA
GCGTCTGGTCAGCAGCGTTCTGGATGCGGCGGTGGTGGTGGACGAACCCATACATCTGCGTTGCTTTGAGTCGACGCACG
AAATGTTGCTCGAACAGCTCAGCCAGCACAAGCTGGATATGATTATCTCCGACTGCCCGATAGATTCCACGCAGCAGGAG
GGGCTATTCTCAGTCAAAATCGGCGAATGCAGCGTCAGTTTCTGGTGTACGAATCCGCTTCCTGAAAAAGCGTTCCCTGC
CTGCCTGGAAGAGCGACGGTTGCTGGTGCCGGGACGTCGCTCAATGCTGGGGCGTAAGTTGTTGAACTGGTTTAATTCGC
AGGGGTTGCAGGTTGAGATCCTCGGTGAATTTGATGACGCGGCCTTAATGAAGGCGTTTGGCGCGACGCATGATGCGATT
TTTGTGGCGCCGAGCCTTTATTCGCTGGATTTTTATGCCGATGAGTCGGTAATAGAGATTGGGCGCGTGGAGAATGTCAT
GGAAGAATATCATGCGATTTTTGCCGAAAGAATGATCCAGCATCCGGCGGTGCAGCGTATTTGCAATGCGGACTACTCGG
CATTGTTTAAGCTTCAGTAG

Upstream 100 bases:

>100_bases
TATAGCTGGTTGCGCGCGCGTTTGAACGCGCCGGCATAACCAGTACGAAGGAAAGGGGGAGCGATGTATCGCTCCCTTAC
GACATTGAACAGGGAGAGAA

Downstream 100 bases:

>100_bases
ACATACCTACCGTAATACTTCCGGCTGCGGTACTAGCCCGCAGCCGGAGTCATTCTACAAATTCAGTAGGCTGCGGTACT
GCCCACCTTCGCGGATAAAC

Product: transcriptional activator NhaR

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSMSHINYNHLYYFWHVYKEGSVVGAAEALFLTPQTITGQIKALEERLQGKLFKRKGRGLEPSELGELVFRYADKMFTLS
QEMLDIVNYRKESNLLFDVGVADALSKRLVSSVLDAAVVVDEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQE
GLFSVKIGECSVSFWCTNPLPEKAFPACLEERRLLVPGRRSMLGRKLLNWFNSQGLQVEILGEFDDAALMKAFGATHDAI
FVAPSLYSLDFYADESVIEIGRVENVMEEYHAIFAERMIQHPAVQRICNADYSALFKLQ

Sequences:

>Translated_299_residues
MSMSHINYNHLYYFWHVYKEGSVVGAAEALFLTPQTITGQIKALEERLQGKLFKRKGRGLEPSELGELVFRYADKMFTLS
QEMLDIVNYRKESNLLFDVGVADALSKRLVSSVLDAAVVVDEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQE
GLFSVKIGECSVSFWCTNPLPEKAFPACLEERRLLVPGRRSMLGRKLLNWFNSQGLQVEILGEFDDAALMKAFGATHDAI
FVAPSLYSLDFYADESVIEIGRVENVMEEYHAIFAERMIQHPAVQRICNADYSALFKLQ
>Mature_298_residues
SMSHINYNHLYYFWHVYKEGSVVGAAEALFLTPQTITGQIKALEERLQGKLFKRKGRGLEPSELGELVFRYADKMFTLSQ
EMLDIVNYRKESNLLFDVGVADALSKRLVSSVLDAAVVVDEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEG
LFSVKIGECSVSFWCTNPLPEKAFPACLEERRLLVPGRRSMLGRKLLNWFNSQGLQVEILGEFDDAALMKAFGATHDAIF
VAPSLYSLDFYADESVIEIGRVENVMEEYHAIFAERMIQHPAVQRICNADYSALFKLQ

Specific function: Plays a role in the positive regulation of nhaA [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=296, Percent_Identity=92.9054054054054, Blast_Score=582, Evalue=1e-168,
Organism=Escherichia coli, GI1788297, Length=248, Percent_Identity=24.5967741935484, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33999; Mature: 33867

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00027 HOMEOBOX_1 ; PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSHINYNHLYYFWHVYKEGSVVGAAEALFLTPQTITGQIKALEERLQGKLFKRKGRGL
CCCCCCCCCEEEEEEEEEECCCEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCC
EPSELGELVFRYADKMFTLSQEMLDIVNYRKESNLLFDVGVADALSKRLVSSVLDAAVVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHC
DEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEGLFSVKIGECSVSFWCTNPL
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCEEEEEEECCCC
PEKAFPACLEERRLLVPGRRSMLGRKLLNWFNSQGLQVEILGEFDDAALMKAFGATHDAI
CHHHHHHHHHCCEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCEE
FVAPSLYSLDFYADESVIEIGRVENVMEEYHAIFAERMIQHPAVQRICNADYSALFKLQ
EEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHEEECC
>Mature Secondary Structure 
SMSHINYNHLYYFWHVYKEGSVVGAAEALFLTPQTITGQIKALEERLQGKLFKRKGRGL
CCCCCCCCEEEEEEEEEECCCEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCC
EPSELGELVFRYADKMFTLSQEMLDIVNYRKESNLLFDVGVADALSKRLVSSVLDAAVVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHC
DEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEGLFSVKIGECSVSFWCTNPL
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCEEEEEEECCCC
PEKAFPACLEERRLLVPGRRSMLGRKLLNWFNSQGLQVEILGEFDDAALMKAFGATHDAI
CHHHHHHHHHCCEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCEE
FVAPSLYSLDFYADESVIEIGRVENVMEEYHAIFAERMIQHPAVQRICNADYSALFKLQ
EEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2429258; 1630901; 9278503; 3413113; 1316901; 8168494 [H]