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The map label for this gene is yeiR [H]

Identifier: 194736397

GI number: 194736397

Start: 2331948

End: 2332961

Strand: Direct

Name: yeiR [H]

Synonym: SeSA_A2452

Alternate gene names: 194736397

Gene position: 2331948-2332961 (Clockwise)

Preceding gene: 194734607

Following gene: 194735858

Centisome position: 49.52

GC content: 55.33

Gene sequence:

>1014_bases
ATGTTGTATCAATATTCTGGAGCTGACGTGACCAAAACCAATCTTATTACTGGATTTCTCGGTAGCGGAAAAACCACCTC
TATCCTTCATTTATTAGCCCATAAAGATCCGGCTGAAAAGTGGGCCGTCCTGGTCAATGAATTTGGCGAAGTGGGTATTG
ACGGCGCGCTGCTTGCCGACAGCGGCGCACTGCTAAAAGAGATCCCCGGCGGCTGCATGTGCTGCGTCAACGGATTGCCT
ATGCAGGTGGGGCTCAACACGCTGCTACGCCAGGGCAAACCTGACCGGTTGCTGATTGAACCAACCGGACTGGGGCACCC
AAAACAGATTCTGGATTTATTAACTGCGCCGGTTTATGAGCCGTGGATTGATTTACGCGCTACGCTCTGCATCCTTGACC
CTCGCCTGCTACTGGACCAACAGAGCGTCGCCAATGAAAATTTCCGCGATCAGCTCGCCTCAGCCGATATTATCATCGCC
AATAAGACCGATCGCGCCACGGCGCAGAGCGATGCCGCCCTGCAACAGTGGTGGCGACAGTACGGCGGCGATCGCCAACT
GATTCATGCCGAACATGGACAGATAGACGGTAAGCTTCTGGATTTACCGCGACAAAATCTGGCGGAACTGCCAGCCAGCG
CCGCGCATTCTCACACTCATGCCAGTAAAAAAGGACTCGCCGCGCTAAATCTGCCCGCACAGCAGCGCTGGCGACGCAGC
CTCAATAGCGGACAAGGTCATCAGGCCTGCGGCTGGATTTTCGATGCCGATACCGTGTTTGACACCATTGGCCTCCTCGA
ATGGGCTCGTCTGGCGCCGGTGGGCCGGGTGAAAGGCGTTATGCGCATACAAGAGGGGCTGGTACGCATCAATCGCCAGG
GCGATGACCTGCACATCGAAACACAGAGTGTCGCGCCGCCGGATAGCCGGGTTGAACTTATCTCAAGCACAGAAACCGAC
TGGAATACGTTACAGACGGCCTTGTTGAAGCTTCGTTTAACGACGCACGCGTAA

Upstream 100 bases:

>100_bases
AAAATTTAACATTTTCTGCTCTTAAGATGGCAGAAGCACGACTTCGTCAACTCAGCGCTTCTCTTTTTCACGTTTATTCG
CCAGGATTATTAAAGTTGTT

Downstream 100 bases:

>100_bases
GGTTGCCACCGTTTAAAAACTATGGCGAAATGACGATGAAAACCCGCTATTCCTTGATAATTCTGCTTAATGCCGCCGGT
CTGGCGCTGTTTTTGTCATG

Product: cobalamin synthesis protein, P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MLYQYSGADVTKTNLITGFLGSGKTTSILHLLAHKDPAEKWAVLVNEFGEVGIDGALLADSGALLKEIPGGCMCCVNGLP
MQVGLNTLLRQGKPDRLLIEPTGLGHPKQILDLLTAPVYEPWIDLRATLCILDPRLLLDQQSVANENFRDQLASADIIIA
NKTDRATAQSDAALQQWWRQYGGDRQLIHAEHGQIDGKLLDLPRQNLAELPASAAHSHTHASKKGLAALNLPAQQRWRRS
LNSGQGHQACGWIFDADTVFDTIGLLEWARLAPVGRVKGVMRIQEGLVRINRQGDDLHIETQSVAPPDSRVELISSTETD
WNTLQTALLKLRLTTHA

Sequences:

>Translated_337_residues
MLYQYSGADVTKTNLITGFLGSGKTTSILHLLAHKDPAEKWAVLVNEFGEVGIDGALLADSGALLKEIPGGCMCCVNGLP
MQVGLNTLLRQGKPDRLLIEPTGLGHPKQILDLLTAPVYEPWIDLRATLCILDPRLLLDQQSVANENFRDQLASADIIIA
NKTDRATAQSDAALQQWWRQYGGDRQLIHAEHGQIDGKLLDLPRQNLAELPASAAHSHTHASKKGLAALNLPAQQRWRRS
LNSGQGHQACGWIFDADTVFDTIGLLEWARLAPVGRVKGVMRIQEGLVRINRQGDDLHIETQSVAPPDSRVELISSTETD
WNTLQTALLKLRLTTHA
>Mature_337_residues
MLYQYSGADVTKTNLITGFLGSGKTTSILHLLAHKDPAEKWAVLVNEFGEVGIDGALLADSGALLKEIPGGCMCCVNGLP
MQVGLNTLLRQGKPDRLLIEPTGLGHPKQILDLLTAPVYEPWIDLRATLCILDPRLLLDQQSVANENFRDQLASADIIIA
NKTDRATAQSDAALQQWWRQYGGDRQLIHAEHGQIDGKLLDLPRQNLAELPASAAHSHTHASKKGLAALNLPAQQRWRRS
LNSGQGHQACGWIFDADTVFDTIGLLEWARLAPVGRVKGVMRIQEGLVRINRQGDDLHIETQSVAPPDSRVELISSTETD
WNTLQTALLKLRLTTHA

Specific function: Unknown

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI223941779, Length=242, Percent_Identity=28.5123966942149, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI126722884, Length=217, Percent_Identity=29.9539170506912, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI33469141, Length=217, Percent_Identity=29.9539170506912, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI146231952, Length=217, Percent_Identity=29.9539170506912, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI148727351, Length=217, Percent_Identity=29.9539170506912, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI223941776, Length=203, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1788499, Length=328, Percent_Identity=87.1951219512195, Blast_Score=596, Evalue=1e-172,
Organism=Escherichia coli, GI87082430, Length=194, Percent_Identity=31.4432989690722, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 36934; Mature: 36934

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYQYSGADVTKTNLITGFLGSGKTTSILHLLAHKDPAEKWAVLVNEFGEVGIDGALLAD
CCEECCCCCCCHHHHEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEC
SGALLKEIPGGCMCCVNGLPMQVGLNTLLRQGKPDRLLIEPTGLGHPKQILDLLTAPVYE
CCHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCHHH
PWIDLRATLCILDPRLLLDQQSVANENFRDQLASADIIIANKTDRATAQSDAALQQWWRQ
HHHHHHHHHEEECCHHHHCCHHHCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHH
YGGDRQLIHAEHGQIDGKLLDLPRQNLAELPASAAHSHTHASKKGLAALNLPAQQRWRRS
HCCCCEEEEECCCCCCCEEECCCHHHHHHCCCHHHHHHHHHHHCCCEEECCCHHHHHHHH
LNSGQGHQACGWIFDADTVFDTIGLLEWARLAPVGRVKGVMRIQEGLVRINRQGDDLHIE
HCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
TQSVAPPDSRVELISSTETDWNTLQTALLKLRLTTHA
ECCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLYQYSGADVTKTNLITGFLGSGKTTSILHLLAHKDPAEKWAVLVNEFGEVGIDGALLAD
CCEECCCCCCCHHHHEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEC
SGALLKEIPGGCMCCVNGLPMQVGLNTLLRQGKPDRLLIEPTGLGHPKQILDLLTAPVYE
CCHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCHHH
PWIDLRATLCILDPRLLLDQQSVANENFRDQLASADIIIANKTDRATAQSDAALQQWWRQ
HHHHHHHHHEEECCHHHHCCHHHCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHH
YGGDRQLIHAEHGQIDGKLLDLPRQNLAELPASAAHSHTHASKKGLAALNLPAQQRWRRS
HCCCCEEEEECCCCCCCEEECCCHHHHHHCCCHHHHHHHHHHHCCCEEECCCHHHHHHHH
LNSGQGHQACGWIFDADTVFDTIGLLEWARLAPVGRVKGVMRIQEGLVRINRQGDDLHIE
HCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
TQSVAPPDSRVELISSTETDWNTLQTALLKLRLTTHA
ECCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]