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The map label for this gene is dtpD [H]

Identifier: 194736313

GI number: 194736313

Start: 842038

End: 843519

Strand: Reverse

Name: dtpD [H]

Synonym: SeSA_A0867

Alternate gene names: 194736313

Gene position: 843519-842038 (Counterclockwise)

Preceding gene: 194734580

Following gene: 194737630

Centisome position: 17.91

GC content: 54.86

Gene sequence:

>1482_bases
ATGAATAAACAAGCATCTCAACCCCGCGCTATTTACTACGTTGTCGCCCTGCAAATTTGGGAGTACTTCAGCTTTTATGG
TATGCGCGCCCTACTGATTCTTTATCTCACCAATCAGCTAAAATACGACGATAACCACGCCTATGAGTTATTCAGCGCTT
ATTGTTCGCTGGTCTACGTAACGCCGATTCTTGGCGGCTATCTGGCGGATAAGGTGCTTGGCAACCGAATGGCAGTCATG
CTGGGCGCATTTTTAATGGCTATAGGTCATTTAGTGCTGGGCGCCAGTGAGATCGCGCCGACATTCCTTTATCTGTCGCT
GGCGATCATTGTCTGCGGCTACGGCCTGTTTAAATCGAATATTAGCTGCCTGCTGGGCGAACTGTACCAGCCGGAAGATC
CGCGCCGCGACGGCGGGTTCTCGCTGCTTTACGCAGCGGGCAATATTGGTTCGATCGTGGCGCCTATCGCCTGCGGCTAT
GTGCAAGAGGAGTACAGTTGGGCGATGGGCTTTGCGCTCGCCGCCATTGGTATGCTGGCGGGGTTAGTGATCTTCCTGTG
TGGAAATCGTCATTTCACCCACACCACCGGCGTGAATAAAGCCGTGTTGTGCGCCAGAAACTACCTGCTGCCGAACTGGG
GCTGGCTGTTAATTCTGCTGGTAGCGGCGCCGTTGCTGATTACCGTTCTGTTCTGGAAAGAATGGTCTGTCTATGCCTTA
ATCGTGGCGACCGCGATCGGCCTGGTCGTGCTGGCAAAAATTTATCGTCAGGCGCAAACGGCCAAACAGCGCAAAGAACT
GGGGCTGATTGTCACCCTGACCCTGTTCAGTATGCTGTTCTGGGCGTTTGCCCAGCAGGGCGGCAGTTCTATCAGCCTGT
ATATCGACCGCTTTGTGAACCGCGATATTCTGGGCTATTCCGTTCCTACCGCCATGTTCCAGTCGGTGAACGCCTTTGCC
GTGATGCTGTGTGGGGTCGTCCTGGCCTGGCTGGTTAAAGAGAGCGTAAGCGGTAATCGCACCGTGCGTATCTGGGGCAA
ATTCGCGCTGGGTCTCGGTCTGATGAGCGCCGGATTCTGTATTCTGACCCTGAGCGCACGCTGGTCCGCCGCTTACGGAC
ACTCTTCAATGCCGCTAATGGTGCTGGGACTGGCGGTGATGGGCTTTGCCGAGCTGTTTATCGACCCGGTCGCCATGTCG
CAAATTACGCGCATTGATATCCCCGGCGTCACCGGCGTATTAACCGGAATTTATATGCTGCTGTCCGGCGCGATAGCTAA
CTATCTGGCAGGCGTCATCGCTGACCAGACCTCGCAAAGCGCCTTCGACGCCAGCAGCGCGGTTAATTACGCCATCAACG
CCTATGTGGATGTTTTTGAACAGATCACCTGGGGCGCGTTAGCCTGCGTAGGGGTTGTCCTGCTGATTTGGCTGTATCAG
TCCTTCAAATTCAAAAGCCGCGCGCTGGCCGTCGAATCCTGA

Upstream 100 bases:

>100_bases
AAGGAAACACGGCGATACGGCAGGCTTAATAAGCCCACAAAGAAAGGCATTATCTGAGAATGCCGCGTTCTTGCCGCAGC
GTCTCTATCCCGGAAATACG

Downstream 100 bases:

>100_bases
TAGCAGAAGGCCCGGTAGTTTGCGCTACCGGGCCTGTATCACGCCCCTTTTCTCGCCGCCTCATAGGCGGAAAGCGTCGC
GATTCTCGCCTGTTTGTGTT

Product: inner membrane transporter YbgH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MNKQASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYDDNHAYELFSAYCSLVYVTPILGGYLADKVLGNRMAVM
LGAFLMAIGHLVLGASEIAPTFLYLSLAIIVCGYGLFKSNISCLLGELYQPEDPRRDGGFSLLYAAGNIGSIVAPIACGY
VQEEYSWAMGFALAAIGMLAGLVIFLCGNRHFTHTTGVNKAVLCARNYLLPNWGWLLILLVAAPLLITVLFWKEWSVYAL
IVATAIGLVVLAKIYRQAQTAKQRKELGLIVTLTLFSMLFWAFAQQGGSSISLYIDRFVNRDILGYSVPTAMFQSVNAFA
VMLCGVVLAWLVKESVSGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAAYGHSSMPLMVLGLAVMGFAELFIDPVAMS
QITRIDIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQSAFDASSAVNYAINAYVDVFEQITWGALACVGVVLLIWLYQ
SFKFKSRALAVES

Sequences:

>Translated_493_residues
MNKQASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYDDNHAYELFSAYCSLVYVTPILGGYLADKVLGNRMAVM
LGAFLMAIGHLVLGASEIAPTFLYLSLAIIVCGYGLFKSNISCLLGELYQPEDPRRDGGFSLLYAAGNIGSIVAPIACGY
VQEEYSWAMGFALAAIGMLAGLVIFLCGNRHFTHTTGVNKAVLCARNYLLPNWGWLLILLVAAPLLITVLFWKEWSVYAL
IVATAIGLVVLAKIYRQAQTAKQRKELGLIVTLTLFSMLFWAFAQQGGSSISLYIDRFVNRDILGYSVPTAMFQSVNAFA
VMLCGVVLAWLVKESVSGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAAYGHSSMPLMVLGLAVMGFAELFIDPVAMS
QITRIDIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQSAFDASSAVNYAINAYVDVFEQITWGALACVGVVLLIWLYQ
SFKFKSRALAVES
>Mature_493_residues
MNKQASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYDDNHAYELFSAYCSLVYVTPILGGYLADKVLGNRMAVM
LGAFLMAIGHLVLGASEIAPTFLYLSLAIIVCGYGLFKSNISCLLGELYQPEDPRRDGGFSLLYAAGNIGSIVAPIACGY
VQEEYSWAMGFALAAIGMLAGLVIFLCGNRHFTHTTGVNKAVLCARNYLLPNWGWLLILLVAAPLLITVLFWKEWSVYAL
IVATAIGLVVLAKIYRQAQTAKQRKELGLIVTLTLFSMLFWAFAQQGGSSISLYIDRFVNRDILGYSVPTAMFQSVNAFA
VMLCGVVLAWLVKESVSGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAAYGHSSMPLMVLGLAVMGFAELFIDPVAMS
QITRIDIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQSAFDASSAVNYAINAYVDVFEQITWGALACVGVVLLIWLYQ
SFKFKSRALAVES

Specific function: Probable proton-dependent permease that transports dipeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=208, Percent_Identity=30.7692307692308, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI226371746, Length=201, Percent_Identity=28.3582089552239, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI226371748, Length=193, Percent_Identity=27.979274611399, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1786927, Length=493, Percent_Identity=88.0324543610548, Blast_Score=904, Evalue=0.0,
Organism=Escherichia coli, GI1790572, Length=484, Percent_Identity=57.6446280991736, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI1787922, Length=472, Percent_Identity=29.6610169491525, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1789911, Length=481, Percent_Identity=27.8586278586279, Blast_Score=186, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17569141, Length=196, Percent_Identity=29.5918367346939, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71987453, Length=175, Percent_Identity=28, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17541704, Length=300, Percent_Identity=25, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639581, Length=330, Percent_Identity=26.0606060606061, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24639583, Length=330, Percent_Identity=26.0606060606061, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24639585, Length=330, Percent_Identity=26.0606060606061, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28571098, Length=204, Percent_Identity=26.9607843137255, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28571102, Length=203, Percent_Identity=27.0935960591133, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28571100, Length=203, Percent_Identity=27.0935960591133, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53849; Mature: 53849

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYDDNHAYELFSAYCSLVYV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
TPILGGYLADKVLGNRMAVMLGAFLMAIGHLVLGASEIAPTFLYLSLAIIVCGYGLFKSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
ISCLLGELYQPEDPRRDGGFSLLYAAGNIGSIVAPIACGYVQEEYSWAMGFALAAIGMLA
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVIFLCGNRHFTHTTGVNKAVLCARNYLLPNWGWLLILLVAAPLLITVLFWKEWSVYAL
HHHHHHHCCCCEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IVATAIGLVVLAKIYRQAQTAKQRKELGLIVTLTLFSMLFWAFAQQGGSSISLYIDRFVN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHC
RDILGYSVPTAMFQSVNAFAVMLCGVVLAWLVKESVSGNRTVRIWGKFALGLGLMSAGFC
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCE
ILTLSARWSAAYGHSSMPLMVLGLAVMGFAELFIDPVAMSQITRIDIPGVTGVLTGIYML
EEEEECCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LSGAIANYLAGVIADQTSQSAFDASSAVNYAINAYVDVFEQITWGALACVGVVLLIWLYQ
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFKFKSRALAVES
HHCHHHHHCCCCC
>Mature Secondary Structure
MNKQASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYDDNHAYELFSAYCSLVYV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
TPILGGYLADKVLGNRMAVMLGAFLMAIGHLVLGASEIAPTFLYLSLAIIVCGYGLFKSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
ISCLLGELYQPEDPRRDGGFSLLYAAGNIGSIVAPIACGYVQEEYSWAMGFALAAIGMLA
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVIFLCGNRHFTHTTGVNKAVLCARNYLLPNWGWLLILLVAAPLLITVLFWKEWSVYAL
HHHHHHHCCCCEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IVATAIGLVVLAKIYRQAQTAKQRKELGLIVTLTLFSMLFWAFAQQGGSSISLYIDRFVN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHC
RDILGYSVPTAMFQSVNAFAVMLCGVVLAWLVKESVSGNRTVRIWGKFALGLGLMSAGFC
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCE
ILTLSARWSAAYGHSSMPLMVLGLAVMGFAELFIDPVAMSQITRIDIPGVTGVLTGIYML
EEEEECCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LSGAIANYLAGVIADQTSQSAFDASSAVNYAINAYVDVFEQITWGALACVGVVLLIWLYQ
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFKFKSRALAVES
HHCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA